NO20066077L - Behandlingsmetode for cancer - Google Patents

Behandlingsmetode for cancer

Info

Publication number
NO20066077L
NO20066077L NO20066077A NO20066077A NO20066077L NO 20066077 L NO20066077 L NO 20066077L NO 20066077 A NO20066077 A NO 20066077A NO 20066077 A NO20066077 A NO 20066077A NO 20066077 L NO20066077 L NO 20066077L
Authority
NO
Norway
Prior art keywords
cancer
administering
relates
treating
treatment
Prior art date
Application number
NO20066077A
Other languages
English (en)
Inventor
Mark S Berger
Iman El-Hariry
Tona Morgan Gilmer
Arundathy Nirmalini Pandite
David Rusnak
Neil L Spector
Original Assignee
Smithkline Beecham Cork Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Cork Ltd filed Critical Smithkline Beecham Cork Ltd
Publication of NO20066077L publication Critical patent/NO20066077L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/86Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/94Nitrogen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Foreliggende oppfinnelse angår en metode for behandling av kreft hos et pattedyr ved administrering av 4-kinazolinaminer, og farmasøytiske preparater inneholdende samme. Spesielt angår metoden en metode for behandling av en krefttype som blir mediert av tyrosinkinasene EGFR og/eller erbB2, ved administrering av N-{3-klor-4-[(3-fluorbenzyl)oksy]fenyl}-6-[5-({[2-(metansulfonyl)etyl]amino}metyl)-2-furyl]-4-kinazolinamin, og salter og solvater derav.
NO20066077A 2004-06-03 2006-12-29 Behandlingsmetode for cancer NO20066077L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US57682504P 2004-06-03 2004-06-03
US60679004P 2004-09-02 2004-09-02
PCT/US2005/019053 WO2005120504A2 (en) 2004-06-03 2005-06-01 Cancer treatment method

Publications (1)

Publication Number Publication Date
NO20066077L true NO20066077L (no) 2007-01-31

Family

ID=35503647

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20066077A NO20066077L (no) 2004-06-03 2006-12-29 Behandlingsmetode for cancer

Country Status (14)

Country Link
US (1) US20100063074A1 (no)
EP (1) EP1768963A4 (no)
JP (1) JP2008501690A (no)
KR (1) KR20070030240A (no)
AU (1) AU2005251722B2 (no)
BR (1) BRPI0511754A (no)
CA (1) CA2569132A1 (no)
IL (1) IL179359A0 (no)
MA (1) MA28691B1 (no)
MX (1) MXPA06013635A (no)
NO (1) NO20066077L (no)
NZ (1) NZ551622A (no)
RU (1) RU2006142420A (no)
WO (1) WO2005120504A2 (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080051422A1 (en) * 2006-08-22 2008-02-28 Concert Pharmaceuticals Inc. 4-Aminoquinazoline derivatives and methods of use thereof
WO2009137714A2 (en) 2008-05-07 2009-11-12 Teva Pharmaceutical Industries Ltd. Forms of lapatinib ditosylate and processes for preparation thereof
US20100197915A1 (en) * 2008-08-06 2010-08-05 Leonid Metsger Lapatinib intermediates
EP2158912A1 (en) * 2008-08-25 2010-03-03 Ratiopharm GmbH Pharmaceutical composition comprising N-[3-chhloro-4-[3-fluorophenyl)methoxy)phenyl]6-[5[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furyl]-4-quinazolinamine
EP2158913A1 (en) 2008-08-25 2010-03-03 Ratiopharm GmbH Pharmaceutical composition comprising N-[3-chhloro-4-[(3-fluorophenyl)methoxy]phenyl]6-(5[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furyl]-4-quinazolinamine
SI2827900T1 (en) 2012-03-23 2018-06-29 Array Biopharma, Inc. Amorphous solid dispersion for use in the treatment of brain cancer
KR20200014298A (ko) 2017-04-28 2020-02-10 시애틀 지네틱스, 인크. Her2 양성 암의 치료

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS49779B (sr) * 1998-01-12 2008-06-05 Glaxo Group Limited, Biciklična heteroaromatična jedinjenja kao inhibitori protein tirozin kinaze
CN1305872C (zh) * 2000-06-30 2007-03-21 葛兰素集团有限公司 喹唑啉类化合物的制备方法
AU2002236765A1 (en) * 2001-01-16 2002-07-30 Glaxo Group Limited Pharmaceutical combination for the treatment of cancer containing a 4-quinazolineamine and another anti-neoplastic agent
JP2004002211A (ja) * 2001-04-27 2004-01-08 Takeda Chem Ind Ltd 癌の予防・治療方法
JP2004002210A (ja) * 2001-04-27 2004-01-08 Takeda Chem Ind Ltd 癌の予防・治療方法
CN100352441C (zh) * 2002-04-16 2007-12-05 阿斯特拉曾尼卡有限公司 用于治疗肿瘤的zd6126和zd1839的联合药物
EP1810034A4 (en) * 2002-06-19 2008-06-25 Smithkline Beecham Corp PREDICTIVE MARKERS IN CANCER THERAPY
CN100522955C (zh) * 2002-08-02 2009-08-05 伊缪诺金公司 含有新型强效紫杉烷的细胞毒性剂及其治疗用途
JP2004144680A (ja) * 2002-10-25 2004-05-20 Nanko Kyo 細胞増殖を制御する物質のスクリーニング方法、及びSp1分子等をヌクレオリン(nucleolin)分子から解離させる物質のスクリーニング方法

Also Published As

Publication number Publication date
US20100063074A1 (en) 2010-03-11
CA2569132A1 (en) 2005-12-22
RU2006142420A (ru) 2008-07-20
NZ551622A (en) 2010-01-29
WO2005120504A3 (en) 2006-02-23
MXPA06013635A (es) 2007-02-28
EP1768963A4 (en) 2009-06-10
JP2008501690A (ja) 2008-01-24
EP1768963A2 (en) 2007-04-04
KR20070030240A (ko) 2007-03-15
MA28691B1 (fr) 2007-06-01
WO2005120504A2 (en) 2005-12-22
AU2005251722B2 (en) 2009-11-12
IL179359A0 (en) 2007-03-08
BRPI0511754A (pt) 2008-01-02
AU2005251722A1 (en) 2005-12-22

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application