NO20064854L - Anvendelse av anti-CTLA-4-antistoffer - Google Patents
Anvendelse av anti-CTLA-4-antistofferInfo
- Publication number
- NO20064854L NO20064854L NO20064854A NO20064854A NO20064854L NO 20064854 L NO20064854 L NO 20064854L NO 20064854 A NO20064854 A NO 20064854A NO 20064854 A NO20064854 A NO 20064854A NO 20064854 L NO20064854 L NO 20064854L
- Authority
- NO
- Norway
- Prior art keywords
- ctla
- antibody
- stem cell
- treatment
- cancer
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Genetics & Genomics (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Mycology (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Transplantation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55680104P | 2004-03-26 | 2004-03-26 | |
| PCT/IB2005/000671 WO2005092380A2 (en) | 2004-03-26 | 2005-03-14 | Uses of anti-ctla-4 antibodies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20064854L true NO20064854L (no) | 2006-12-22 |
Family
ID=35056778
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20064854A NO20064854L (no) | 2004-03-26 | 2006-10-25 | Anvendelse av anti-CTLA-4-antistoffer |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20050226875A1 (https=) |
| EP (1) | EP1732600A2 (https=) |
| JP (1) | JP2007530526A (https=) |
| KR (1) | KR100845354B1 (https=) |
| CN (1) | CN1964739A (https=) |
| AR (1) | AR049480A1 (https=) |
| AU (1) | AU2005225227A1 (https=) |
| BR (1) | BRPI0509274A (https=) |
| CA (1) | CA2560919A1 (https=) |
| IL (1) | IL177602A0 (https=) |
| NO (1) | NO20064854L (https=) |
| RU (1) | RU2346702C2 (https=) |
| TW (2) | TW200829271A (https=) |
| WO (1) | WO2005092380A2 (https=) |
| ZA (1) | ZA200607544B (https=) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006101691A1 (en) * | 2005-03-23 | 2006-09-28 | Pfizer Products Inc. | Therapy of prostate cancer with ctla4 antibodies and hormonal therapy |
| KR20070104673A (ko) * | 2005-03-23 | 2007-10-26 | 화이자 프로덕츠 인코포레이티드 | 암의 치료를 위한 항-ctla4 항체와 인돌리논병용요법 |
| CA2603093A1 (en) | 2005-03-31 | 2006-10-05 | Agensys, Inc. | Antibodies and related molecules that bind to 161p2f10b proteins |
| WO2010014784A2 (en) | 2008-08-01 | 2010-02-04 | Bristol-Myers Squibb Company | Combination of anti-ctla4 antibody with diverse therapeutic regimens for the synergistic treatment of proliferative diseases |
| EP2365823B1 (en) | 2008-10-30 | 2016-11-30 | Yeda Research And Development Company Ltd. | Anti third party central memory t cells, methods of producing same and use of same in transplantation and disease treatment |
| SMT201700293T1 (it) * | 2009-07-20 | 2017-07-18 | Bristol Myers Squibb Co | Combinazione di un anticorpo anti-ctla-4 con etoposide per il trattamento sinergico di malattie proliferative |
| AU2011213609B2 (en) | 2010-02-08 | 2016-11-03 | Agensys, Inc. | Antibody drug conjugates (ADC) that bind to 161P2F10B proteins |
| KR20130105652A (ko) * | 2010-09-08 | 2013-09-25 | 예다 리서치 앤드 디벨럽먼트 캄파니 리미티드 | 안정하고 장기간의 인그래프트먼트를 위한 면역억제 약물의 조합 |
| MX357746B (es) | 2010-09-08 | 2018-07-23 | Yeda Res And Development Co Ltd Star | Uso de células t de memoria central anti-tercera parte para el tratamiento anti-leucemia/linfoma. |
| EP3409287B9 (en) | 2010-09-29 | 2021-07-21 | Agensys, Inc. | Antibody drug conjugates (adc) that bind to 191p4d12 proteins |
| WO2013013029A1 (en) | 2011-07-19 | 2013-01-24 | The Board Of Trustees Of The University Of Illinois | Anti-clta4, anti-glut2 protein for the treatment of type 1 diabetes |
| AU2012305931B2 (en) | 2011-09-08 | 2017-09-07 | Yeda Research And Development Co. Ltd | Anti third party central memory T cells, methods of producing same and use of same in transplantation and disease treatment |
| AU2013255511B2 (en) | 2012-05-04 | 2016-01-28 | Pfizer Inc. | Prostate-associated antigens and vaccine-based immunotherapy regimens |
| EP3494996B1 (en) | 2012-08-23 | 2026-04-15 | Agensys, Inc. | Antibody drug conjugates (adc) that bind to 158p1d7 proteins |
| JP6510518B2 (ja) | 2013-08-01 | 2019-05-08 | アジェンシス,インコーポレイテッド | Cd37タンパク質に結合する抗体薬物結合体(adc) |
| SG10201912986PA (en) | 2014-05-28 | 2020-02-27 | Agenus Inc | Anti-gitr antibodies and methods of use thereof |
| CN105296433B (zh) | 2014-08-01 | 2018-02-09 | 中山康方生物医药有限公司 | 一种ctla4抗体、其药物组合物及其用途 |
| JP6991857B2 (ja) | 2014-10-10 | 2022-01-13 | イデラ ファーマシューティカルズ インコーポレイテッド | Tlr9アゴニストをチェックポイント阻害剤と共に用いるがんの治療 |
| CN108271359B (zh) * | 2015-02-13 | 2021-11-09 | 索伦托药业有限公司 | 结合ctla4的抗体治疗剂 |
| ES2884844T3 (es) | 2015-03-09 | 2021-12-13 | Agensys Inc | Conjugados de anticuerpo fármaco (ADC) que se unen a proteínas FLT3 |
| WO2016187354A1 (en) | 2015-05-18 | 2016-11-24 | Agensys, Inc. | Antibodies that bind to axl proteins |
| WO2016187356A1 (en) | 2015-05-18 | 2016-11-24 | Agensys, Inc. | Antibodies that bind to axl proteins |
| MA44594B1 (fr) | 2015-05-29 | 2020-09-30 | Memorial Sloan Kettering Cancer Center | Anticorps anti-ctla-4 et méthodes d'utilisation de ceux-ci |
| JP7057748B2 (ja) | 2015-07-16 | 2022-04-20 | イェダ リサーチ アンド ディベロップメント カンパニー リミテッド | 遺伝子改変された抗第三者中枢性メモリーt細胞および免疫療法におけるその使用 |
| RU2619208C2 (ru) * | 2015-10-08 | 2017-05-12 | ДИАМОНДЗЛИТЕ ЛИМИТЕД Тридент Чамберс | Способ профилактического лечения при развитии неопластических процессов кожной ткани, таких как меланома, базально-клеточный рак, плоскоклеточный рак |
| IL299072A (en) | 2015-12-02 | 2023-02-01 | Memorial Sloan Kettering Cancer Center | Antibodies and methods for using them |
| CN109310885B (zh) | 2016-03-15 | 2022-05-31 | 梅尔莎纳医疗公司 | NaPi2b靶向抗体-药物缀合物及其使用方法 |
| RU2021127872A (ru) | 2016-06-30 | 2021-11-09 | Онкорус, Инк. | Доставка терапевтических полипептидов посредством псевдотипированных онколитических вирусов |
| WO2018035710A1 (en) | 2016-08-23 | 2018-03-01 | Akeso Biopharma, Inc. | Anti-ctla4 antibodies |
| WO2018098352A2 (en) | 2016-11-22 | 2018-05-31 | Jun Oishi | Targeting kras induced immune checkpoint expression |
| US11135307B2 (en) | 2016-11-23 | 2021-10-05 | Mersana Therapeutics, Inc. | Peptide-containing linkers for antibody-drug conjugates |
| WO2018106862A1 (en) | 2016-12-07 | 2018-06-14 | Agenus Inc. | Anti-ctla-4 antibodies and methods of use thereof |
| US10751368B2 (en) | 2017-01-18 | 2020-08-25 | Yeda Research And Development Co. Ltd. | Methods of transplantation and disease treatment |
| CN110392736A (zh) | 2017-01-18 | 2019-10-29 | 耶达研究及发展有限公司 | 遗传修饰的反抑细胞及其在免疫治疗中的用途 |
| TW201834697A (zh) | 2017-02-28 | 2018-10-01 | 美商梅爾莎納醫療公司 | Her2標靶抗體-藥物結合物之組合療法 |
| CA3073984A1 (en) | 2017-09-21 | 2019-03-28 | Eucure (Beijing) Biopharma Co., Ltd | Anti-ctla4 antibodies and uses thereof |
| EP3717021A1 (en) | 2017-11-27 | 2020-10-07 | Mersana Therapeutics, Inc. | Pyrrolobenzodiazepine antibody conjugates |
| BR112020012364A2 (pt) | 2017-12-20 | 2020-11-24 | Harbour Biomed (Shanghai) Co., Ltd | anticorpos de ligação a ctla-4 e usos dos mesmos |
| EP3727463A1 (en) | 2017-12-21 | 2020-10-28 | Mersana Therapeutics, Inc. | Pyrrolobenzodiazepine antibody conjugates |
| US11865081B2 (en) | 2017-12-29 | 2024-01-09 | Virogin Biotech Canada Ltd. | Oncolytic viral delivery of therapeutic polypeptides |
| US12391746B2 (en) | 2018-02-20 | 2025-08-19 | Emory University | HPV proteins, antibodies, and uses in managing abnormal epithelial cell growth |
| AU2019369340A1 (en) | 2018-10-29 | 2021-05-20 | Mersana Therapeutics, Inc. | Cysteine engineered antibody-drug conjugates with peptide-containing linkers |
| IL283522B2 (en) | 2018-12-03 | 2025-03-01 | Agensys Inc | Pharmaceutical compositions containing anti-191P4D12 antibody drug conjugates and methods of using them |
| WO2020214690A1 (en) | 2019-04-15 | 2020-10-22 | Qwixel Therapeutics | Fusion protein composition(s) comprising targeted masked type i interferons (ifna and ifnb) and an antibody against tumor antigen, for use in the treatment of cancer |
| CA3145347A1 (en) | 2019-07-15 | 2021-01-21 | Intervet International B.V. | Caninized antibodies to human and canine ctla-4 |
| WO2021066869A1 (en) | 2019-10-04 | 2021-04-08 | TAE Life Sciences | Antibody compositions comprising fc mutations and site-specific conjugation properties |
| US12159700B2 (en) | 2020-04-22 | 2024-12-03 | Iovance Biotherapeutics, Inc. | Systems and methods for coordinating manufacturing of cells for patient-specific immunotherapy |
| AR122043A1 (es) * | 2020-05-12 | 2022-08-03 | Bristol Myers Squibb Co | Dosificación y administración del anticuerpo anti-ctla-4 activable |
| US20230372397A1 (en) | 2020-10-06 | 2023-11-23 | Iovance Biotherapeutics, Inc. | Treatment of nsclc patients with tumor infiltrating lymphocyte therapies |
| JP2023545099A (ja) | 2020-10-08 | 2023-10-26 | アフィメド ゲーエムベーハー | 三重特異性バインダー |
| AU2022246174A1 (en) | 2021-03-25 | 2023-09-14 | Iovance Biotherapeutics, Inc. | Methods and compositions for t-cell coculture potency assays and use with cell therapy products |
| JP2024523290A (ja) | 2021-06-18 | 2024-06-28 | ナミ セラピューティクス, インコーポレイテッド | がんの処置およびその方法における使用のための、マスクされたI型インターフェロン(IFNαおよびIFNβ)を含む融合タンパク質組成物 |
| CA3216098A1 (en) | 2021-07-30 | 2023-02-02 | Uwe Reusch | Duplexbodies |
| CA3248034A1 (en) | 2022-04-15 | 2023-10-19 | Iovance Biotherapeutics, Inc. | METHODS FOR EXPANSION OF TIL CELLS BY MEANS OF SPECIFIC CYTOKINE COMBINATIONS AND/OR AKT INHIBITOR TREATMENT |
| EP4623072A2 (en) | 2022-11-21 | 2025-10-01 | Iovance Biotherapeutics, Inc. | Two-dimensional processes for the expansion of tumor infiltrating lymphocytes and therapies therefrom |
| EP4727971A1 (en) | 2023-06-13 | 2026-04-22 | Adcentrx Therapeutics Inc. | Methods and compositions related to antibodies and antibody drug conjugates (adcs) that bind nectin-4 proteins |
| WO2025034812A2 (en) | 2023-08-07 | 2025-02-13 | Tae Life Sciences Llc | Trifluoroborate (bf3) compositions for use in boron neutron capture therapy and methods thereof |
| WO2025264533A1 (en) | 2024-06-17 | 2025-12-26 | Adcentrx Therapeutics Inc. | Methods and compositions related to antibody drug conjugates (adcs) that bind steap-1 proteins |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5811097A (en) * | 1995-07-25 | 1998-09-22 | The Regents Of The University Of California | Blockade of T lymphocyte down-regulation associated with CTLA-4 signaling |
| DK1141028T3 (da) * | 1998-12-23 | 2010-05-25 | Pfizer | Humane monoklonale antistoffer til CTLA-4 |
| US6682736B1 (en) * | 1998-12-23 | 2004-01-27 | Abgenix, Inc. | Human monoclonal antibodies to CTLA-4 |
| IL148079A0 (en) * | 1999-08-24 | 2002-09-12 | Medarex Inc | Human ctla-4 antibodies and compositions containing the same |
| US7605238B2 (en) * | 1999-08-24 | 2009-10-20 | Medarex, Inc. | Human CTLA-4 antibodies and their uses |
| JP3871503B2 (ja) * | 1999-08-30 | 2007-01-24 | 日本たばこ産業株式会社 | 免疫性疾患治療剤 |
| IL149701A0 (en) * | 2001-05-23 | 2002-11-10 | Pfizer Prod Inc | Use of anti-ctla-4 antibodies |
| BR0309254A (pt) * | 2002-04-12 | 2005-03-01 | Medarex Inc | Uso de um anticorpo anti-ctla-4 |
-
2005
- 2005-03-14 EP EP05708756A patent/EP1732600A2/en not_active Withdrawn
- 2005-03-14 CA CA002560919A patent/CA2560919A1/en not_active Abandoned
- 2005-03-14 AU AU2005225227A patent/AU2005225227A1/en not_active Abandoned
- 2005-03-14 RU RU2006134045/14A patent/RU2346702C2/ru not_active IP Right Cessation
- 2005-03-14 WO PCT/IB2005/000671 patent/WO2005092380A2/en not_active Ceased
- 2005-03-14 CN CNA2005800098282A patent/CN1964739A/zh active Pending
- 2005-03-14 KR KR1020067019856A patent/KR100845354B1/ko not_active Expired - Fee Related
- 2005-03-14 BR BRPI0509274-4A patent/BRPI0509274A/pt not_active IP Right Cessation
- 2005-03-14 JP JP2007504498A patent/JP2007530526A/ja not_active Withdrawn
- 2005-03-21 US US11/085,368 patent/US20050226875A1/en not_active Abandoned
- 2005-03-22 AR ARP050101117A patent/AR049480A1/es unknown
- 2005-03-25 TW TW097102213A patent/TW200829271A/zh unknown
- 2005-03-25 TW TW094109392A patent/TW200602078A/zh unknown
-
2006
- 2006-08-21 IL IL177602A patent/IL177602A0/en unknown
- 2006-09-08 ZA ZA200607544A patent/ZA200607544B/en unknown
- 2006-10-25 NO NO20064854A patent/NO20064854L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| RU2006134045A (ru) | 2008-03-27 |
| US20050226875A1 (en) | 2005-10-13 |
| CN1964739A (zh) | 2007-05-16 |
| RU2346702C2 (ru) | 2009-02-20 |
| ZA200607544B (en) | 2008-07-30 |
| KR100845354B1 (ko) | 2008-07-09 |
| IL177602A0 (en) | 2006-12-10 |
| CA2560919A1 (en) | 2005-10-06 |
| JP2007530526A (ja) | 2007-11-01 |
| WO2005092380A2 (en) | 2005-10-06 |
| WO2005092380A3 (en) | 2006-06-15 |
| KR20070007114A (ko) | 2007-01-12 |
| AR049480A1 (es) | 2006-08-09 |
| BRPI0509274A (pt) | 2007-09-04 |
| TW200829271A (en) | 2008-07-16 |
| AU2005225227A1 (en) | 2005-10-06 |
| TW200602078A (en) | 2006-01-16 |
| EP1732600A2 (en) | 2006-12-20 |
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