NO20063958L - HIV integrase inhibitorer - Google Patents

HIV integrase inhibitorer

Info

Publication number
NO20063958L
NO20063958L NO20063958A NO20063958A NO20063958L NO 20063958 L NO20063958 L NO 20063958L NO 20063958 A NO20063958 A NO 20063958A NO 20063958 A NO20063958 A NO 20063958A NO 20063958 L NO20063958 L NO 20063958L
Authority
NO
Norway
Prior art keywords
integrase inhibitors
hiv integrase
hiv
treatment
aids
Prior art date
Application number
NO20063958A
Other languages
English (en)
Norwegian (no)
Inventor
Eric Eugene Boros
Ronald George Sherrill
Brian A Johns
Cecilia Koble
Takashi Kawasuji
Noriyuki Kurose
Hitoshi Mural
Jason Gordon Weatherhead
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of NO20063958L publication Critical patent/NO20063958L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO20063958A 2004-02-11 2006-09-05 HIV integrase inhibitorer NO20063958L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54367004P 2004-02-11 2004-02-11
PCT/US2005/004085 WO2005077050A2 (en) 2004-02-11 2005-02-10 Hiv integrase inhibitors

Publications (1)

Publication Number Publication Date
NO20063958L true NO20063958L (no) 2006-09-22

Family

ID=34860447

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20063958A NO20063958L (no) 2004-02-11 2006-09-05 HIV integrase inhibitorer

Country Status (15)

Country Link
US (3) US8691991B2 (ja)
EP (1) EP1720856B1 (ja)
JP (1) JP4859676B2 (ja)
KR (1) KR20070002006A (ja)
CN (1) CN1976915A (ja)
AU (1) AU2005211733A1 (ja)
BR (1) BRPI0507628A (ja)
CA (1) CA2555176A1 (ja)
ES (1) ES2433477T3 (ja)
IL (1) IL177189A0 (ja)
MA (1) MA28358A1 (ja)
MX (1) MXPA06009132A (ja)
NO (1) NO20063958L (ja)
RU (1) RU2006128848A (ja)
WO (1) WO2005077050A2 (ja)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1720856B1 (en) 2004-02-11 2013-08-14 GlaxoSmithKline LLC Hiv integrase inhibitors
DK2465580T3 (en) 2005-04-28 2014-03-10 Viiv Healthcare Co POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVES WITH HIV INTEGRASE INHIBITIVE ACTIVITY
US20080194523A1 (en) * 2005-08-04 2008-08-14 Smithkline Beecham Corporation Hiv Integrase Inhibitors
WO2007019130A2 (en) * 2005-08-04 2007-02-15 Smithkline Beecham Corporation Hiv integrase inhibitors
JP2009503081A (ja) * 2005-08-04 2009-01-29 スミスクライン ビーチャム コーポレーション Ｈｉｖインテグラーゼ阻害薬
WO2007019101A2 (en) * 2005-08-04 2007-02-15 Smithkline Beecham Corporation Hiv integrase inhibitors
TW200808793A (en) * 2006-03-07 2008-02-16 Smithkline Beecham Corp Prolyl hydroxylase inhibitors
CN101454319B (zh) 2006-05-26 2012-06-27 富山化学工业株式会社 新杂环化合物或其盐及其中间体
EP1956016A1 (en) * 2006-12-15 2008-08-13 Bayer Schering Pharma Aktiengesellschaft Bicyclic acyltryptophanols
EP2111399A2 (en) 2006-12-18 2009-10-28 Amgen Inc. Naphthalenone compounds exhibiting prolyl hydroxylase inhibitory activity, compositions, and uses thereof
ES2393326T3 (es) 2006-12-18 2012-12-20 Amgen, Inc Compuestos basados en azaquinolona que presentan actividad inhibidora de prolil hidroxilasas, composiciones y usos de los mismos
CA2683956C (en) 2007-04-18 2012-12-18 Amgen Inc. Quinolones and azaquinolones that inhibit prolyl hydroxylase
JP2010524935A (ja) * 2007-04-18 2010-07-22 メルク・シャープ・エンド・ドーム・コーポレイション 新規１，８−ナフチリジン化合物
US7569726B2 (en) 2007-04-18 2009-08-04 Amgen Inc. Indanone derivatives that inhibit prolyl hydroxylase
ES2389063T3 (es) 2007-05-04 2012-10-22 Amgen, Inc Derivados de tienopiridina y tiazolopiridina que inhiben la actividad prolil hidroxilasa
CA2685219C (en) 2007-05-04 2012-06-19 Amgen Inc. Diazaquinolones that inhibit prolyl hydroxylase activity
WO2010011818A1 (en) * 2008-07-25 2010-01-28 Smithkline Beecham Corporation Chemical compounds
WO2010011819A1 (en) * 2008-07-25 2010-01-28 Smithkline Beecham Corporation Chemical compounds
US8283366B2 (en) * 2010-01-22 2012-10-09 Ambrilia Biopharma, Inc. Derivatives of pyridoxine for inhibiting HIV integrase
AU2011209788C1 (en) * 2010-01-27 2014-08-28 Viiv Healthcare Company Antiviral therapy
US20110223131A1 (en) * 2010-02-24 2011-09-15 Gilead Sciences, Inc. Antiviral compounds
MY175079A (en) * 2010-04-02 2020-06-04 Firmenich Incorporated Sweet flavor modifier
MX2013004169A (es) 2010-10-14 2013-06-05 Immunahr Ab 1, 2-dihidro-4-hidroxi-2-oxo-quinolina-3-carboxanilidas como activadores del receptor de hidrocarburo aromatico.
PL2648516T3 (pl) 2010-12-06 2019-04-30 Aclaris Therapeutics Inc Podstawione związki pirydynono-pirydynylowe
US9359300B2 (en) 2010-12-06 2016-06-07 Confluence Life Sciences, Inc. Methyl/difluorophenyl-methoxy substituted pyridinone-pyridinyl compounds, methyl-pyridinyl-methoxy substituted pyridinone-pyridinyl compounds, and methyl-pyrimidinyl-methoxy substituted pyridinone-pyridinyl compounds
US8883779B2 (en) 2011-04-26 2014-11-11 Shinogi & Co., Ltd. Oxazine derivatives and a pharmaceutical composition for inhibiting BACE1 containing them
MY179876A (en) 2011-08-12 2020-11-18 Firmenich Incorporated Sweet flavor modifier
MX357940B (es) 2012-12-21 2018-07-31 Gilead Sciences Inc Compuestos de carbamoilpiridona policiclicos y su uso farmaceutico.
KR102470598B1 (ko) 2013-06-07 2022-11-23 어클라리스 쎄라퓨틱스, 인코포레이티드 메틸/플루오로-피리디닐-메톡시 치환된 피리디논-피리디닐 화합물 및 플루오로-피리미디닐-메톡시 치환된 피리디논-피리디닐 화합물
MX2017005931A (es) 2014-11-07 2017-06-30 Senomyx Inc Acidos 4-amino-5- (ciclohexiloxi) quinolina-3-carboxilicos sustituidos como modificadores del sabor dulce.
CN105348282B (zh) * 2015-12-02 2018-06-29 北京工业大学 一种hiv-1整合酶抑制剂化合物及其制备方法和应用
KR20220161390A (ko) 2020-03-27 2022-12-06 어클라리스 쎄라퓨틱스, 인코포레이티드 면역 병태의 치료를 위한 mk2 경로 억제제의 경구 조성물
US11116737B1 (en) 2020-04-10 2021-09-14 University Of Georgia Research Foundation, Inc. Methods of using probenecid for treatment of coronavirus infections

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2274913T3 (es) 2000-10-12 2007-06-01 MERCK & CO., INC. Aza y poliaza-naftalenil carboxamidas utiles como inhibidores de vih integrada.
US20050010048A1 (en) 2000-10-12 2005-01-13 Linghang Zhuang Aza-and polyaza-naphthalenly ketones useful as hiv integrase inhibitors
AU1152702A (en) 2000-10-12 2002-04-22 Merck & Co Inc Aza- and polyaza-naphthalenyl carboxamides useful as hiv integrase inhibitors
US6919351B2 (en) 2000-10-12 2005-07-19 Merck & Co., Inc. Aza-and polyaza-naphthalenyl-carboxamides useful as HIV integrase inhibitors
ATE411292T1 (de) 2001-03-01 2008-10-15 Shionogi & Co Stickstoffhaltige heteroarylverbindungen mit hiv- integrase inhibierender wirkung
DE60315796T2 (de) * 2002-01-17 2008-06-05 Merck & Co., Inc. Hydroxynaphthyridinoncarbonsäureamide, die sich als inhibitoren der hiv-integrase eignen
US7358249B2 (en) * 2002-08-13 2008-04-15 Shionogi & Co., Ltd. Heterocyclic compounds having inhibitory activity against HIV integrase
AU2003265674B2 (en) 2002-08-29 2008-12-11 Merck & Co., Inc. N-biarylmethyl aminocycloalkanecarboxamide derivatives
TW200505902A (en) * 2003-03-20 2005-02-16 Schering Corp Cannabinoid receptor ligands
WO2005023189A2 (en) 2003-09-03 2005-03-17 Pharmacia Corporation Method of cox-2 selective inhibitor and nitric oxide-donating agent
CA2537325A1 (en) 2003-09-19 2005-03-31 Gilead Sciences, Inc. Aza-quinolinol phosphonate integrase inhibitor compounds
EP1720856B1 (en) 2004-02-11 2013-08-14 GlaxoSmithKline LLC Hiv integrase inhibitors

Also Published As

Publication number Publication date
AU2005211733A1 (en) 2005-08-25
IL177189A0 (en) 2006-12-10
CA2555176A1 (en) 2005-08-25
CN1976915A (zh) 2007-06-06
ES2433477T3 (es) 2013-12-11
KR20070002006A (ko) 2007-01-04
EP1720856A4 (en) 2009-11-11
EP1720856A2 (en) 2006-11-15
US20140256713A1 (en) 2014-09-11
MXPA06009132A (es) 2007-03-26
JP4859676B2 (ja) 2012-01-25
MA28358A1 (fr) 2006-12-01
WO2005077050A3 (en) 2006-11-23
WO2005077050A2 (en) 2005-08-25
EP1720856B1 (en) 2013-08-14
BRPI0507628A (pt) 2007-07-03
RU2006128848A (ru) 2008-03-20
JP2007523086A (ja) 2007-08-16
US8691991B2 (en) 2014-04-08
US20070124152A1 (en) 2007-05-31
US20150225399A1 (en) 2015-08-13

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