NO20063112L - Forbedret syntese av 2-substituerte adenosiner - Google Patents

Forbedret syntese av 2-substituerte adenosiner

Info

Publication number
NO20063112L
NO20063112L NO20063112A NO20063112A NO20063112L NO 20063112 L NO20063112 L NO 20063112L NO 20063112 A NO20063112 A NO 20063112A NO 20063112 A NO20063112 A NO 20063112A NO 20063112 L NO20063112 L NO 20063112L
Authority
NO
Norway
Prior art keywords
substituted
alkoxy
halo
cyano
nitro
Prior art date
Application number
NO20063112A
Other languages
English (en)
Inventor
Edward Daniel Savory
Original Assignee
Biovitrum Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biovitrum Ab filed Critical Biovitrum Ab
Publication of NO20063112L publication Critical patent/NO20063112L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/167—Purine radicals with ribosyl as the saccharide radical
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

En fremgangsmåte av syntese av et 2-substituert andenosin av formel I som omfatter å omdanne en forbindelse av formel II til en forbindelse av formel (I), hvor: R = Ci-6 alkoksy (rett eller forgrenet), en fenoksygruppe (ikke-substituert eller mono- eller di-substituert ved halo, almino, CF3., cyano, nitro, C1-6 alkyl eller Ci_6 alkoksy) en benzyloksygruppe (ikke-substituert eller mono- eller di-substituert ved halo, amino, CF3., cyano, nitro, Ci-6 alkyl eller Ci-6 alkoksy), eller en benzoylgruppe (ikke-substituert, eller mono- eller di-substituert ved halo, amino, CF3., cyano, nitro, Ci-6 alkyl eller Q-6 alkoksy); R' = H, eller en beskyttende gruppe.
NO20063112A 2003-12-05 2006-07-04 Forbedret syntese av 2-substituerte adenosiner NO20063112L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0328323.1A GB0328323D0 (en) 2003-12-05 2003-12-05 Synthesis of 2-substituted adenosines
PCT/GB2004/005092 WO2005054269A1 (en) 2003-12-05 2004-12-03 Improved synthesis of 2-substituted adenosines

Publications (1)

Publication Number Publication Date
NO20063112L true NO20063112L (no) 2006-09-05

Family

ID=29764714

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20063112A NO20063112L (no) 2003-12-05 2006-07-04 Forbedret syntese av 2-substituerte adenosiner

Country Status (12)

Country Link
US (1) US20080262214A1 (no)
EP (1) EP1697393A1 (no)
JP (1) JP2007513135A (no)
KR (1) KR20060125829A (no)
CN (1) CN100532389C (no)
AU (1) AU2004295172A1 (no)
CA (1) CA2552591A1 (no)
GB (1) GB0328323D0 (no)
HK (1) HK1097850A1 (no)
NO (1) NO20063112L (no)
NZ (1) NZ546781A (no)
WO (1) WO2005054269A1 (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005012324A2 (en) * 2003-07-30 2005-02-10 Gilead Sciences, Inc. Nucleobase phosphonate analogs for antiviral treatment
AU2005218997B2 (en) * 2004-03-05 2012-05-10 Cbt Development Limited Adenosine receptor agonists
BRPI0713902A2 (pt) 2006-06-27 2012-11-27 Biovitrum Ab compostos terapêuticos
CN102464689A (zh) * 2010-11-17 2012-05-23 天津康鸿医药科技发展有限公司 一种用于合成腺苷的中间体化合物的制备方法
CN103342727A (zh) * 2013-07-01 2013-10-09 淮海工学院 一种2-甲氧基腺苷的合成方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1119440C (zh) * 2000-12-27 2003-08-27 天津南开戈德集团有限公司 一种紫外荧光纤维的制造方法

Also Published As

Publication number Publication date
AU2004295172A1 (en) 2005-06-16
WO2005054269A1 (en) 2005-06-16
CA2552591A1 (en) 2005-06-16
CN100532389C (zh) 2009-08-26
HK1097850A1 (en) 2007-07-06
EP1697393A1 (en) 2006-09-06
NZ546781A (en) 2010-02-26
KR20060125829A (ko) 2006-12-06
GB0328323D0 (en) 2004-01-07
US20080262214A1 (en) 2008-10-23
CN1886415A (zh) 2006-12-27
JP2007513135A (ja) 2007-05-24

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application