NO20062616L - Nye forbindelse, samsvarende sammensetninger, fremstilling og/eller behandlingsmetoder - Google Patents

Nye forbindelse, samsvarende sammensetninger, fremstilling og/eller behandlingsmetoder

Info

Publication number
NO20062616L
NO20062616L NO20062616A NO20062616A NO20062616L NO 20062616 L NO20062616 L NO 20062616L NO 20062616 A NO20062616 A NO 20062616A NO 20062616 A NO20062616 A NO 20062616A NO 20062616 L NO20062616 L NO 20062616L
Authority
NO
Norway
Prior art keywords
preparation
treatment methods
new compounds
compositions
matching compositions
Prior art date
Application number
NO20062616A
Other languages
English (en)
Inventor
Orco Philip C Dell
Ann Marie Diederich
Qiaogang Su
Jeffery Lee Wood
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of NO20062616L publication Critical patent/NO20062616L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)

Abstract

Det beskrives en ny, krystallinsk form av topotecanmonohydrokloridpentahydrat. Forbindelsen er et pentahydrat av 10-[(dimetylamino)metyl]-4-etyl-4,9-dihydroksy-1H-pyranol[3',4': 6,7]indolizino[1,2-b]kinolin-3,14(4H,12H)dionmonohydroklorid. Videre beskrives farmasøytiske preparater, fremstillingsmetoder og/eller bruk derav for å behandle antivirale og/eller cancerrelaterte sykdommer.
NO20062616A 2003-11-12 2006-06-07 Nye forbindelse, samsvarende sammensetninger, fremstilling og/eller behandlingsmetoder NO20062616L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US51916003P 2003-11-12 2003-11-12
US52457403P 2003-11-24 2003-11-24
PCT/US2004/037626 WO2005046608A2 (en) 2003-11-12 2004-11-12 Novel compound, corresponding compositions, preparation and/or treatment methods

Publications (1)

Publication Number Publication Date
NO20062616L true NO20062616L (no) 2006-07-12

Family

ID=34594951

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20062616A NO20062616L (no) 2003-11-12 2006-06-07 Nye forbindelse, samsvarende sammensetninger, fremstilling og/eller behandlingsmetoder

Country Status (16)

Country Link
US (2) US7754733B2 (no)
EP (1) EP1689400A4 (no)
JP (1) JP2007510751A (no)
KR (1) KR20060122847A (no)
CN (1) CN1913897B (no)
AR (1) AR046579A1 (no)
AU (1) AU2004289318B2 (no)
BR (1) BRPI0416366A (no)
CA (1) CA2545876A1 (no)
IL (1) IL175369A (no)
IS (1) IS8491A (no)
MA (1) MA28179A1 (no)
NO (1) NO20062616L (no)
RU (1) RU2352572C2 (no)
TW (1) TWI333492B (no)
WO (1) WO2005046608A2 (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR046579A1 (es) * 2003-11-12 2005-12-14 Smithkline Beecham Corp Compuesto cristalino de topotecan, composicion farmaceutica que lo comprende, procedimiento para prepararlo y su uso para preparar dicha composicion farmaceutica
EP1943253A1 (en) 2005-10-10 2008-07-16 Cipla Limited Novel crystalline forms
US7547785B2 (en) * 2005-12-26 2009-06-16 Dr. Reddy's Laboratories Limited Process for preparing topotecan
US7977483B2 (en) * 2007-04-11 2011-07-12 Scinopharm Taiwan, Ltd. Process for making topotecan
NZ580516A (en) * 2007-04-19 2012-02-24 Scinopharm Taiwan Ltd Crystalline forms of topotecan hydrochloride and processes for making the same
US7572803B2 (en) * 2007-10-25 2009-08-11 The Christus Stehlin Foundation For Cancer Research Hydrated crystalline esters of camptothecin
ITMI20072268A1 (it) 2007-12-04 2009-06-05 Antibioticos Spa Polimorfi cristallini di topotecan cloridrato con elevato grado di purezza e metodi per la loro preparazione
WO2023220641A2 (en) 2022-05-11 2023-11-16 Juno Therapeutics, Inc. Methods and uses related to t cell therapy and production of same

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5004758A (en) * 1987-12-01 1991-04-02 Smithkline Beecham Corporation Water soluble camptothecin analogs useful for inhibiting the growth of animal tumor cells
JP2848958B2 (ja) * 1990-09-28 1999-01-20 スミスクライン・ビーチャム・コーポレイション 水溶性カンプトテシン類似体、方法および手段
AR013261A1 (es) * 1997-08-01 2000-12-13 Smithkline Beecham Corp Formulaciones farmaceuticas para analogos de camptotecina en capsula de gelatina
HUP0401912A3 (en) * 2001-09-25 2007-02-28 Reddys Lab Ltd Dr Pharmaceutically acceptable salts of 20(s)-camptothecins, process for their preparation and pharmaceutical compositions containing them
US7049322B2 (en) * 2002-02-21 2006-05-23 Supergen, Inc. Compositions and formulations of 9-nitrocamptothecin polymorphs and methods of use therefor
AR046579A1 (es) * 2003-11-12 2005-12-14 Smithkline Beecham Corp Compuesto cristalino de topotecan, composicion farmaceutica que lo comprende, procedimiento para prepararlo y su uso para preparar dicha composicion farmaceutica
EP1943253A1 (en) * 2005-10-10 2008-07-16 Cipla Limited Novel crystalline forms
US7547785B2 (en) * 2005-12-26 2009-06-16 Dr. Reddy's Laboratories Limited Process for preparing topotecan
NZ580516A (en) 2007-04-19 2012-02-24 Scinopharm Taiwan Ltd Crystalline forms of topotecan hydrochloride and processes for making the same
ITMI20072268A1 (it) * 2007-12-04 2009-06-05 Antibioticos Spa Polimorfi cristallini di topotecan cloridrato con elevato grado di purezza e metodi per la loro preparazione

Also Published As

Publication number Publication date
BRPI0416366A (pt) 2007-03-13
TWI333492B (en) 2010-11-21
RU2006120422A (ru) 2007-12-27
KR20060122847A (ko) 2006-11-30
US8158645B2 (en) 2012-04-17
AU2004289318B2 (en) 2010-04-29
EP1689400A4 (en) 2006-12-27
CN1913897A (zh) 2007-02-14
AR046579A1 (es) 2005-12-14
US20070117832A1 (en) 2007-05-24
WO2005046608A3 (en) 2005-11-03
IL175369A (en) 2012-03-29
JP2007510751A (ja) 2007-04-26
IL175369A0 (en) 2008-04-13
US7754733B2 (en) 2010-07-13
WO2005046608B1 (en) 2005-12-29
RU2352572C2 (ru) 2009-04-20
AU2004289318A1 (en) 2005-05-26
CA2545876A1 (en) 2005-05-26
TW200530250A (en) 2005-09-16
MA28179A1 (fr) 2006-09-01
IS8491A (is) 2006-05-30
WO2005046608A2 (en) 2005-05-26
CN1913897B (zh) 2010-08-11
EP1689400A2 (en) 2006-08-16
US20100210677A1 (en) 2010-08-19

Similar Documents

Publication Publication Date Title
NO20062616L (no) Nye forbindelse, samsvarende sammensetninger, fremstilling og/eller behandlingsmetoder
ATE370138T1 (de) Neue imidazopyridine und ihre verwendung
ATE437872T1 (de) Proteinkinaseinhibitoren
ATE365742T1 (de) 4-aminothieno(2,3-d) pyrimidin -6-carbonitril- derivative zur verwendung als pde7 inhibitoren
WO2001064639A3 (en) Pde iv inhibiting amides, compositions and pharmaceutical use
MXPA05012466A (es) Derivados de quinolina como inhibidores de fosfodiesterasa.
NO20051263L (no) Ny anvendelse av benzotiazolderivater
HU0102272D0 (en) Compositions and methods for stimulating gastrointestinal motilis
ECSP055809A (es) Inhibidores 4-oxo-1-(3-fenil sustituido)-1,4-dihidro-1,8-naftiridina-3-carboxamida de la fosfodiesterasa-4
GB0112348D0 (en) Compounds
EA200600811A1 (ru) НОВЫЕ ПРОИЗВОДНЫЕ ТЕТРАГИДРОСПИРО {ПИПЕРИДИН-2,7'-ПИРРОЛО [3,2-b]ПИРИДИНА} И НОВЫЕ ПРОИЗВОДНЫЕ ИНДОЛА, ПРИМЕНЕНИЕ ДЛЯ ЛЕЧЕНИЯ РАССТРОЙСТВ, СВЯЗАННЫХ С 5-HT-РЕЦЕПТОРОМ
NO20070837L (no) Pyrido-pyrido pyrimidinderivater, fremstilling derav samt terapeutisk anvendelse for behandling av cancer.
WO2000068198A3 (en) Heterosubstituted pyridine derivatives as pde 4 inhibitors
CY1109366T1 (el) Υποκατεστημενες ενωσεις 1,4,8-τριαζασπειρο[4.5]δεκαν-2-ονης
AP1564A (en) Piperazinyl sulfonic acid derivatives, their pharmaceutical compositions and methods of use.
IL156827A (en) Derivatives of 2-mercapto- [3,1] thiazolo [4,5 [b- pyridine and pharmaceutical preparations containing them for the treatment of cardiovascular disease
MY133527A (en) Isoquinoline derivatives
HUP0301458A2 (hu) Benzoxazinonszármazékok, eljárás előállításukra és a vegyületek felhasználása
TW200504029A (en) Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
CA2354606A1 (en) Azabicycloalkane derivatives and therapeutic uses thereof
WO2000064874A3 (en) Heterosubstituted pyridine derivatives as pde 4 inhibitors
TW200504030A (en) Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
ATE390923T1 (de) Topoisomerase-giftmittel
NO20055997L (no) Diarylmetylidenpiperidinderivater og deres anvendelse som opiodreseptoragonister
GB0319037D0 (en) 7-Azaindole Derivatives

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application