NO20052223L - Tiazolforbindelser for behandling av neurodegenerative forstyrrelser - Google Patents
Tiazolforbindelser for behandling av neurodegenerative forstyrrelserInfo
- Publication number
- NO20052223L NO20052223L NO20052223A NO20052223A NO20052223L NO 20052223 L NO20052223 L NO 20052223L NO 20052223 A NO20052223 A NO 20052223A NO 20052223 A NO20052223 A NO 20052223A NO 20052223 L NO20052223 L NO 20052223L
- Authority
- NO
- Norway
- Prior art keywords
- treatment
- neurodegenerative disorders
- thiazole compounds
- compounds
- formula
- Prior art date
Links
- 208000015122 neurodegenerative disease Diseases 0.000 title 1
- 150000003557 thiazoles Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- FBKFDSUZBVDZIX-FFGDOFBPSA-N (4s)-4-[[(2s)-2-[[(2s)-2-[[2-[[(2s)-2-[[(2s)-2-acetamido-3-phenylpropanoyl]amino]-4-methylsulfanylbutanoyl]amino]-2-methylpropanoyl]amino]-3-[4-(phosphonomethyl)phenyl]propanoyl]amino]-3-(6-chloro-1h-indol-3-yl)propanoyl]amino]-5-[[1-[[(2s)-1-amino-4-meth Chemical compound C([C@@H](C(=O)N[C@@H](CCSC)C(=O)NC(C)(C)C(=O)N[C@@H](CC=1C=CC(CP(O)(O)=O)=CC=1)C(=O)N[C@@H](CC=1C2=CC=C(Cl)C=C2NC=1)C(=O)N[C@@H](CCC(O)=O)C(=O)NC1(CC1)C(=O)N[C@@H](CC(C)C)C(N)=O)NC(C)=O)C1=CC=CC=C1 FBKFDSUZBVDZIX-FFGDOFBPSA-N 0.000 abstract 1
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/54—Nitrogen and either oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41740002P | 2002-10-09 | 2002-10-09 | |
| US46320903A | 2003-06-17 | 2003-06-17 | |
| PCT/IB2003/004330 WO2004033439A1 (en) | 2002-10-09 | 2003-09-29 | Thiazole compounds for the treatment of neurodegenerative disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20052223D0 NO20052223D0 (no) | 2005-05-06 |
| NO20052223L true NO20052223L (no) | 2005-07-04 |
Family
ID=35306299
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20052223A NO20052223L (no) | 2002-10-09 | 2005-05-06 | Tiazolforbindelser for behandling av neurodegenerative forstyrrelser |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US20040152747A1 (is) |
| EP (1) | EP1551815A1 (is) |
| JP (1) | JP2006504796A (is) |
| KR (1) | KR20050070046A (is) |
| CN (1) | CN1688557A (is) |
| AP (1) | AP2005003274A0 (is) |
| AR (1) | AR043051A1 (is) |
| AU (1) | AU2003265068A1 (is) |
| BR (1) | BR0314611A (is) |
| CA (1) | CA2501803A1 (is) |
| CO (1) | CO5550435A2 (is) |
| CR (1) | CR7785A (is) |
| EC (1) | ECSP055719A (is) |
| GT (1) | GT200300219A (is) |
| IS (1) | IS7738A (is) |
| MA (1) | MA27451A1 (is) |
| MX (1) | MXPA05002420A (is) |
| NL (1) | NL1024499C2 (is) |
| NO (1) | NO20052223L (is) |
| OA (1) | OA12937A (is) |
| PA (1) | PA8585001A1 (is) |
| PE (1) | PE20040640A1 (is) |
| PL (1) | PL376171A1 (is) |
| TN (1) | TNSN05104A1 (is) |
| TW (1) | TW200420550A (is) |
| UY (1) | UY28011A1 (is) |
| WO (1) | WO2004033439A1 (is) |
| ZA (1) | ZA200502841B (is) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2842523A1 (fr) * | 2002-07-17 | 2004-01-23 | Sanofi Synthelabo | Derives d'acylaminothiazole, leur preparation et leur application en therapeutique |
| CA2524511A1 (en) * | 2003-05-12 | 2004-11-18 | Pfizer Products Inc. | Isoxazole and isothiazole compounds for the treatment of neurodegenerative disorders |
| BRPI0413349A (pt) * | 2003-08-06 | 2006-10-10 | Pfizer Prod Inc | compostos de oxazol para o tratamento de doenças neurodegenerativas |
| WO2005073202A1 (fr) * | 2004-01-16 | 2005-08-11 | Sanofi-Aventis | Derives d’acylaminothiazole et leur application comme inhibiteurs de beta-amyloide |
| RU2401262C2 (ru) * | 2004-01-16 | 2010-10-10 | Санофи-Авентис | Производные алкиламинотиазола, их получение и их применение в терапии |
| FR2865207B1 (fr) * | 2004-01-16 | 2008-10-17 | Sanofi Synthelabo | Derives d'acylaminothiazole, leur preparation et leur application en therapeutique |
| FR2873374B1 (fr) * | 2004-07-22 | 2006-10-20 | Sanofi Synthelabo | Derives d'acylaminothiazole, leur preparation et leur application en therapeutique |
| FR2865206B1 (fr) * | 2004-01-16 | 2009-02-06 | Sanofi Synthelabo | Derives d'acylaminothiazole, leur preparation et leur application en therapeutique |
| FR2873370B1 (fr) * | 2004-07-22 | 2006-10-20 | Sanofi Synthelabo | Derives d'acylaminothiazole, leur preparation et leur application en therapeutique |
| UA83899C2 (uk) * | 2004-03-23 | 2008-08-26 | Пфайзер Продактс Інк. | Сполуки імідазолу для лікування нейродегенеративних розладів |
| US7220865B2 (en) * | 2004-04-01 | 2007-05-22 | Pfizer Inc | Isoxazole-and isothiazole-amine compounds for the treatment of neurodegenerative disorders |
| US7384968B2 (en) * | 2004-04-01 | 2008-06-10 | Pfizer Inc. | Thiazole-amine compounds for the treatment of neurodegenerative disorders |
| KR20070049655A (ko) | 2004-08-13 | 2007-05-11 | 제넨테크, 인크. | Atp-이용 효소 억제 활성을 나타내는2-아미도-티아졸-기재 화합물과 조성물 및 이들의 용도 |
| EA017166B1 (ru) * | 2005-05-24 | 2012-10-30 | Мерк Сероно С.А. | Производные тиазола и их применение |
| FR2887879B1 (fr) * | 2005-07-01 | 2008-09-26 | Trophos Sa | Nouveaux composes chimiques et leurs utilisations comme medicament,particulierement dans le traitement des maladies neurodegeneratives |
| KR20080040010A (ko) * | 2005-09-22 | 2008-05-07 | 화이자 프로덕츠 인코포레이티드 | 신경계 질환 치료용 이미다졸 화합물 |
| CA2631750A1 (en) | 2005-12-01 | 2007-06-07 | The Scripps Research Institute | Compositions and methods for inducing neuronal differentiation |
| CN101421265A (zh) * | 2006-01-18 | 2009-04-29 | 安姆根有限公司 | 作为蛋白激酶b(pkb)抑制剂的噻唑化合物 |
| EP1918286B1 (en) * | 2006-11-05 | 2011-12-21 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Thiazolhydrazides for treatment of neurodegenerative diseases |
| GB0701426D0 (en) * | 2007-01-25 | 2007-03-07 | Univ Sheffield | Compounds and their use |
| US7919504B2 (en) * | 2007-07-17 | 2011-04-05 | Amgen Inc. | Thiadiazole modulators of PKB |
| CA2692713A1 (en) | 2007-07-17 | 2009-01-22 | Amgen Inc. | Heterocyclic modulators of pkb |
| RU2401837C2 (ru) * | 2008-05-19 | 2010-10-20 | Государственное образовательное учреждение высшего профессионального образования "Пермская государственная фармацевтическая академия Федерального агентства по здравоохранению и социальному развитию" (ГОУ ВПО ПГФА Росздрава) | N-(2-тиазолил)амид 2-(2-оксо-3-индолинилиден)гидразино-4-оксо-4-фенил-2-бутеновой кислоты, обладающий противомикробной и анальгетической активностью |
| NZ590285A (en) * | 2008-07-15 | 2012-10-26 | Novartis Ag | Heteroaryl derivatives as dgat1 inhibitors |
| WO2010096371A2 (en) | 2009-02-18 | 2010-08-26 | Boehringer Ingelheim International Gmbh | Heterocyclic compounds which modulate the cb2 receptor |
| WO2010126002A1 (ja) * | 2009-04-28 | 2010-11-04 | 塩野義製薬株式会社 | ヘテロ環スルホンアミド化合物を含有する医薬 |
| US8299103B2 (en) * | 2009-06-15 | 2012-10-30 | Boehringer Ingelheim International Gmbh | Compounds which selectively modulate the CB2 receptor |
| US9315454B2 (en) | 2010-01-15 | 2016-04-19 | Boehringer Ingelheim International Gmbh | Compounds which modulate the CB2 receptor |
| WO2012012307A1 (en) | 2010-07-22 | 2012-01-26 | Boehringer Ingelheim International Gmbh | Sulfonyl compounds which modulate the cb2 rece |
| CN102351854B (zh) * | 2011-07-29 | 2014-06-04 | 华中科技大学 | 氨基噻唑衍生物及制备方法和医药用途 |
| RS58768B1 (sr) * | 2013-03-14 | 2019-06-28 | Merck Patent Gmbh | Inhibitori glikozidaze |
| EP2803668A1 (en) | 2013-05-17 | 2014-11-19 | Boehringer Ingelheim International Gmbh | Novel (cyano-dimethyl-methyl)-isoxazoles and -[1,3,4]thiadiazoles |
| CN103408541B (zh) * | 2013-07-16 | 2015-04-01 | 浙江医药高等专科学校 | 吲哚取代的噻唑并环己烷类化合物、及其抗肿瘤用途 |
| CN103435573B (zh) * | 2013-07-16 | 2015-04-01 | 浙江医药高等专科学校 | 苄基取代的噻唑并环己烷类化合物、其制备方法和用途 |
| GB201401886D0 (en) | 2014-02-04 | 2014-03-19 | Lytix Biopharma As | Neurodegenerative therapies |
| EP3643703A4 (en) * | 2017-06-21 | 2020-12-23 | Daiichi Sankyo Co., Ltd. | EP300 / CREBBP INHIBITOR |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992021360A1 (en) * | 1991-05-28 | 1992-12-10 | Merck & Co., Inc. | Substituted n-carboxyalkylpeptidyl derivatives as antidegenerative active agents |
| CO5021134A1 (es) * | 1998-05-01 | 2001-03-27 | Abbott Lab | Inhibidores beta-aminoacidos substituidos de aminopeptida- sa-2 metionina |
| SK16282000A3 (sk) * | 1998-05-01 | 2001-05-10 | Abbott Laboratories | Substituované beta-aminokyselinové inhibítory metionínaminopeptidázy-2 |
| AU6229699A (en) * | 1998-10-26 | 2000-05-15 | Sumitomo Pharmaceuticals Company, Limited | Beta-amyloid formation inhibitors |
| AR039059A1 (es) * | 2001-08-06 | 2005-02-09 | Sanofi Aventis | Compuesto derivado de acilaminotiazol, su utilizacion, procedimientos para prepararlo, composicion farmaceutica que lo comprende, y compuestos intermediarios |
| FR2842523A1 (fr) * | 2002-07-17 | 2004-01-23 | Sanofi Synthelabo | Derives d'acylaminothiazole, leur preparation et leur application en therapeutique |
-
2003
- 2003-09-29 CA CA002501803A patent/CA2501803A1/en not_active Abandoned
- 2003-09-29 KR KR1020057006168A patent/KR20050070046A/ko not_active Ceased
- 2003-09-29 PL PL03376171A patent/PL376171A1/xx not_active Application Discontinuation
- 2003-09-29 MX MXPA05002420A patent/MXPA05002420A/es not_active Application Discontinuation
- 2003-09-29 AU AU2003265068A patent/AU2003265068A1/en not_active Abandoned
- 2003-09-29 WO PCT/IB2003/004330 patent/WO2004033439A1/en not_active Ceased
- 2003-09-29 JP JP2005501002A patent/JP2006504796A/ja active Pending
- 2003-09-29 BR BR0314611-1A patent/BR0314611A/pt not_active IP Right Cessation
- 2003-09-29 EP EP03807933A patent/EP1551815A1/en not_active Withdrawn
- 2003-09-29 CN CNA038240106A patent/CN1688557A/zh active Pending
- 2003-09-29 OA OA1200500098A patent/OA12937A/en unknown
- 2003-09-29 AP AP2005003274A patent/AP2005003274A0/xx unknown
- 2003-10-03 TW TW092127495A patent/TW200420550A/zh unknown
- 2003-10-07 PE PE2003001021A patent/PE20040640A1/es not_active Application Discontinuation
- 2003-10-08 US US10/682,686 patent/US20040152747A1/en not_active Abandoned
- 2003-10-08 PA PA20038585001A patent/PA8585001A1/es unknown
- 2003-10-08 AR ARP030103662A patent/AR043051A1/es unknown
- 2003-10-09 GT GT200300219A patent/GT200300219A/es unknown
- 2003-10-09 NL NL1024499A patent/NL1024499C2/nl not_active IP Right Cessation
- 2003-10-09 UY UY28011A patent/UY28011A1/es not_active Application Discontinuation
-
2005
- 2005-03-10 IS IS7738A patent/IS7738A/is unknown
- 2005-04-07 EC EC2005005719A patent/ECSP055719A/es unknown
- 2005-04-07 CR CR7785A patent/CR7785A/es not_active Application Discontinuation
- 2005-04-08 TN TNP2005000104A patent/TNSN05104A1/fr unknown
- 2005-04-08 MA MA28206A patent/MA27451A1/fr unknown
- 2005-04-08 CO CO05031337A patent/CO5550435A2/es not_active Application Discontinuation
- 2005-05-06 NO NO20052223A patent/NO20052223L/no unknown
-
2006
- 2006-01-17 ZA ZA200502841A patent/ZA200502841B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1688557A (zh) | 2005-10-26 |
| TNSN05104A1 (fr) | 2007-05-14 |
| EP1551815A1 (en) | 2005-07-13 |
| PE20040640A1 (es) | 2004-09-15 |
| NO20052223D0 (no) | 2005-05-06 |
| US20040152747A1 (en) | 2004-08-05 |
| PA8585001A1 (es) | 2004-12-16 |
| AR043051A1 (es) | 2005-07-13 |
| MXPA05002420A (es) | 2005-10-05 |
| KR20050070046A (ko) | 2005-07-05 |
| PL376171A1 (en) | 2005-12-27 |
| CA2501803A1 (en) | 2004-04-22 |
| JP2006504796A (ja) | 2006-02-09 |
| ZA200502841B (en) | 2006-03-29 |
| WO2004033439A1 (en) | 2004-04-22 |
| AU2003265068A1 (en) | 2004-05-04 |
| OA12937A (en) | 2006-10-13 |
| MA27451A1 (fr) | 2005-07-01 |
| IS7738A (is) | 2005-03-10 |
| CR7785A (es) | 2005-07-08 |
| TW200420550A (en) | 2004-10-16 |
| NL1024499A1 (nl) | 2004-04-13 |
| CO5550435A2 (es) | 2005-08-31 |
| GT200300219A (es) | 2004-05-18 |
| UY28011A1 (es) | 2004-04-30 |
| AP2005003274A0 (en) | 2005-06-30 |
| NL1024499C2 (nl) | 2004-10-13 |
| BR0314611A (pt) | 2005-07-26 |
| ECSP055719A (es) | 2005-07-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO20052223L (no) | Tiazolforbindelser for behandling av neurodegenerative forstyrrelser | |
| NO20064726L (no) | Imidazolforbindelser for behandling av neurodegenerative forstyrrelser | |
| CA2501799A1 (en) | Pyrazole compounds for treatment of neurodegenerative disorders | |
| NO20071719L (no) | Pyridylinhibitorer for "hedgehog"-signalisering | |
| DK2527315T3 (da) | Forbindelser, præparater og fremgangsmåder til behandling af amyloide sygdomme og synukleinopatier, såsom Alzheimers sygdom, type 2-diabetes og Parkinsons sygdom | |
| NO20045137L (no) | Diketohydrazinderivatforbindelser og legemidler inneholdende forbindelser som aktiv ingrediens | |
| GB0318447D0 (en) | Therapeutic agents | |
| CA2473070A1 (en) | Proline compounds as ns3-serine protease inhibitors for use in treatment of hepatites c virus infection | |
| MXPA05011150A (es) | 2-hidroxi-3-diaminoalcanos de benzamida. | |
| MXPA04003245A (es) | Hidroxipropilaminas. | |
| MXPA04002785A (es) | Aminas sustituidas para tratamiento de enfermedad de alzheimer. | |
| TW200505828A (en) | Substituted ureas and carbamates useful in the treatment of alzheimer's disease | |
| WO2005037798A3 (en) | Amide or thiomide derivatives and their use in the treatment of pain | |
| ATE371724T1 (de) | Behandlung neurodegenerativer krankheiten | |
| CA2534532A1 (en) | Compounds for the treatment of neurodegenerative disorders | |
| BR0316723A (pt) | Derivados de anilinopirazol úteis para o tratamento de diabetes | |
| MXPA05012196A (es) | Compuestos de isoxazol e isotiazol para el tratamiento de trastornos neurodegenerativos. | |
| MXPA03011466A (es) | Macrociclos utiles en tratamiento de enfermedades de alzheimer. | |
| NO20044530L (no) | Fremgangsmate for behandling av kognitive forstyrrelser | |
| NO20060020L (no) | 3-fluorpiperidiner som NMDA/NR2B-antagonister | |
| DE602004010314D1 (de) | Behandlung von neurodegenerativen erkrankungen durch verwendung von degs-inhibitoren | |
| MX2010002765A (es) | Derivado de 6-pirimidinil-pirimid-4-ona. | |
| NO20064989L (no) | Sulfonamidforbindelser for behandling av neurodegenerative lidelser | |
| NO20044531L (no) | Imidazolinylmetyl-aralkylsulfonamider, blandinger omfattende slike, fremgangsmate for fremstilling av slike, slike forbindelser som medikament samt anvendelse av slike forbindelser for fremstilling av medikamenter for behandling av sykdom | |
| NO20081845L (no) | Imidazolforbindelser for behandling av neurologiske lidelser |