FR2865207B1 - Derives d'acylaminothiazole, leur preparation et leur application en therapeutique - Google Patents
Derives d'acylaminothiazole, leur preparation et leur application en therapeutiqueInfo
- Publication number
- FR2865207B1 FR2865207B1 FR0400388A FR0400388A FR2865207B1 FR 2865207 B1 FR2865207 B1 FR 2865207B1 FR 0400388 A FR0400388 A FR 0400388A FR 0400388 A FR0400388 A FR 0400388A FR 2865207 B1 FR2865207 B1 FR 2865207B1
- Authority
- FR
- France
- Prior art keywords
- preparation
- therapeutic application
- acylaminothiazole derivatives
- acylaminothiazole
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/36—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/54—Nitrogen and either oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (15)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0400388A FR2865207B1 (fr) | 2004-01-16 | 2004-01-16 | Derives d'acylaminothiazole, leur preparation et leur application en therapeutique |
AT05717377T ATE517098T1 (de) | 2004-01-16 | 2005-01-07 | Acylaminothiazolderivate und deren verwendung als beta-amyloid-inhibitoren |
JP2006548340A JP4813371B2 (ja) | 2004-01-16 | 2005-01-07 | アシルアミノチアゾール誘導体及びβ−アミロイド阻害剤としてのこれらの使用 |
ES05717377T ES2369918T3 (es) | 2004-01-16 | 2005-01-07 | Derivados de acilaminotiazol y su aplicación como inhibidores de beta-amiloide. |
PCT/FR2005/000029 WO2005073202A1 (fr) | 2004-01-16 | 2005-01-07 | Derives d’acylaminothiazole et leur application comme inhibiteurs de beta-amyloide |
DK05717377.5T DK1709018T3 (da) | 2004-01-16 | 2005-01-07 | Acylaminothiazolderivater og anvendelse deraf som beta-amyloid-hæmmere |
SI200531394T SI1709018T1 (sl) | 2004-01-16 | 2005-01-07 | Acilaminotiazolni derivati in njihova uporaba kotbeta-amiloidni inhibitorji |
EP05717377A EP1709018B1 (fr) | 2004-01-16 | 2005-01-07 | Derives d'acylaminothiazole et leur application comme inhibiteurs de beta-amyloide |
CNA2005800025883A CN1910165A (zh) | 2004-01-16 | 2005-01-07 | 酰基氨基噻唑衍生物及其作为β-淀粉状蛋白抑制剂的用途 |
PT05717377T PT1709018E (pt) | 2004-01-16 | 2005-01-07 | Derivados de acilaminotiazole e sua aplicação como inibidores |
TW094100684A TWI350287B (en) | 2004-01-16 | 2005-01-11 | Acylaminothiazole derivatives, their preparation and their therapeutic application |
ARP050100110A AR047383A1 (es) | 2004-01-16 | 2005-01-13 | Derivados de acilaminotiazol, su preparacion y su aplicacion en terapeutica |
IL176772A IL176772A0 (en) | 2004-01-16 | 2006-07-10 | Acylaminothiazole derivatives and use thereof as beta-amyloid inhibitors |
US11/457,490 US7371770B2 (en) | 2004-01-16 | 2006-07-14 | Acylaminothiazole derivatives and use thereof as β-amyloid inhibitors |
US12/051,924 US7759377B2 (en) | 2004-01-16 | 2008-03-20 | Acylaminothiazole derivatives and use thereof as beta-amyloid inhibitors |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0400388A FR2865207B1 (fr) | 2004-01-16 | 2004-01-16 | Derives d'acylaminothiazole, leur preparation et leur application en therapeutique |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2865207A1 FR2865207A1 (fr) | 2005-07-22 |
FR2865207B1 true FR2865207B1 (fr) | 2008-10-17 |
Family
ID=34707892
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR0400388A Expired - Fee Related FR2865207B1 (fr) | 2004-01-16 | 2004-01-16 | Derives d'acylaminothiazole, leur preparation et leur application en therapeutique |
Country Status (3)
Country | Link |
---|---|
CN (1) | CN1910165A (fr) |
ES (1) | ES2369918T3 (fr) |
FR (1) | FR2865207B1 (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200922564A (en) * | 2007-09-10 | 2009-06-01 | Curis Inc | CDK inhibitors containing a zinc binding moiety |
WO2010075542A1 (fr) | 2008-12-23 | 2010-07-01 | Curis, Inc. | Inhibiteurs de cdk |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR039059A1 (es) * | 2001-08-06 | 2005-02-09 | Sanofi Aventis | Compuesto derivado de acilaminotiazol, su utilizacion, procedimientos para prepararlo, composicion farmaceutica que lo comprende, y compuestos intermediarios |
PL376171A1 (en) * | 2002-10-09 | 2005-12-27 | Pfizer Products Inc. | Thiazole compounds for the treatment of neurodegenerative disorders |
-
2004
- 2004-01-16 FR FR0400388A patent/FR2865207B1/fr not_active Expired - Fee Related
-
2005
- 2005-01-07 CN CNA2005800025883A patent/CN1910165A/zh active Pending
- 2005-01-07 ES ES05717377T patent/ES2369918T3/es active Active
Also Published As
Publication number | Publication date |
---|---|
ES2369918T3 (es) | 2011-12-09 |
CN1910165A (zh) | 2007-02-07 |
FR2865207A1 (fr) | 2005-07-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MA28575B1 (fr) | Derives de la 1-amino-phthalazine, leur preparation , et leur application en therapeutique | |
MA28734B1 (fr) | Derives de 2-carbamide-4-phenylthiazole, leur preparation et leur application en therapeutique | |
FR2854158B1 (fr) | Derives de 2-acylamino-4-phenylethiazole, leur preparation et leur application en therapeutique | |
FR2864080B1 (fr) | Derives de 1-piperazine-et-1-homopiperazine-carboxylates, leur preparation et leur application en therapeutique | |
MA28343A1 (fr) | Derives de type aryloxyalkylcarbamates, leur preparation et leur application en therapeutique | |
FR2866884B1 (fr) | Derives d'aryl-et d'heteroaryl-piperidinecarboxylates, leur preparation et leur application en therapeutique | |
FR2882054B1 (fr) | Derives de 1,5-diarylpyrrole, leur preparation et leur application en therapeutique | |
FR2854633B1 (fr) | Derives de piperidinyl-et piperazinyl-alkylcarbamates, leur preparation et leur application en therapeutique | |
FR2873691B1 (fr) | Derives d'amino-piperidine, leur preparation et leur application en therapeutique | |
MA29017B1 (fr) | Derives de 2-amido-4-phenylthiazole, leur preparation et leur application en therapeutique | |
MA27049A1 (fr) | Derives de 1-phenylsulfonyl-1,3-dihydro-2h-indol-2-one, leur preparation et leur application en therapeutique | |
FR2843964B1 (fr) | Derives de dioxane-2-alkylcarbamates, leur preparation et leur application en therapeutique | |
FR2885364B1 (fr) | Derives d'alkyl-, alkenyl-et alkynylcarbamates, leur preparation et leur application en therapeutique | |
FR2866888B1 (fr) | Derives de alkylpiperazine- et alkylhomopiperazine- carboxylates, leur preparation et leur application en therapeutique | |
FR2888847B1 (fr) | Derives de n-(heteriaryl)-1-heteorarylalkyl-1h-indole-2- carboxamides, leur preparation et application en therapeutique | |
FR2881744B1 (fr) | Derives de n-[(4,5-diphenyl-2-thienyl)methyl]amine, leur preparation et leur application en therapeutique | |
FR2850377B1 (fr) | Derives d'arylalkylcarbamates, leur preparation et leur application en therapeutique | |
MA28720B1 (fr) | Derives de tetrahydroisoquinolilsulfonamides, leur preparation et leur utilisation en therapeutique | |
MA27233A1 (fr) | Derives de piperazinylacylpiperidine, leur preparation et leur application en therapeutique | |
FR2864958B1 (fr) | Derive de n-[(1,5-diphenyl-1h-pyrazol-3-yl)methyl] sulfonamide, leur preparation et leur application en therapeutique. | |
FR2856684B1 (fr) | Derives de diphenylpyridine, leur preparation et leur application en therapeutique | |
FR2866885B1 (fr) | Derives de piperidinylalkylcarbamates, leur prepation et leur application en therapeutique | |
FR2891825B1 (fr) | Derives de la 1-amino-isoquinoline, leur preparation et leur application en therapeutique | |
FR2873690B1 (fr) | Derives d'oxopiperidine, leur preparation et leur application en therapeutique | |
FR2887548B1 (fr) | Derives de 4,5-diarylpyrrole, leur preparation et leur application en therapeutique |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
CD | Change of name or company name | ||
ST | Notification of lapse |
Effective date: 20120928 |