NO20051441L - Biodegraderbar sammensetning med vedvarende frigivelse av den biologisk aktive forbindelse og fremstilling av slike - Google Patents

Biodegraderbar sammensetning med vedvarende frigivelse av den biologisk aktive forbindelse og fremstilling av slike

Info

Publication number
NO20051441L
NO20051441L NO20051441A NO20051441A NO20051441L NO 20051441 L NO20051441 L NO 20051441L NO 20051441 A NO20051441 A NO 20051441A NO 20051441 A NO20051441 A NO 20051441A NO 20051441 L NO20051441 L NO 20051441L
Authority
NO
Norway
Prior art keywords
sub
polyhydric alcohol
preparation
active compound
biologically active
Prior art date
Application number
NO20051441A
Other languages
English (en)
Inventor
Milan Dittrich
Petr Sova
Original Assignee
Pliva Lachema As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva Lachema As filed Critical Pliva Lachema As
Publication of NO20051441L publication Critical patent/NO20051441L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Oppfinnelsen angår biodegraderbare sammensetninger med vedvarende frigivelse av biologisk aktive forbindelser, der sammensetningen inneholder minst en biologisk aktiv forbindelse og en bærer, som er basert på en biodegraderbar oligoester med antallsgjennomsnittlig molekylvekt Mfra 650 til 7 500, molekylvektgjennomsnitt Mw fra 800 til 10 000 og glassovergangstemperatur Tg -35 til 45°C, og som fremstilles ved polykondenseringsreaksjon av polyol inneholdende minst tre hydroksygrupper med minst en alifatisk a-hydroksysyre i molare forhold mellom polyolen og den alifatiske a-hydroksysyren fra 0,5:99,5 til 12:88, der det sentrale molekylet i den biodegraderbare oligoesteren er en polyol der hy droksy gruppene binder kjeder av ulike molekyler av minst en alifatisk a-hydroksysyre ved esterbindinger.
NO20051441A 2002-08-22 2005-03-18 Biodegraderbar sammensetning med vedvarende frigivelse av den biologisk aktive forbindelse og fremstilling av slike NO20051441L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CZ20022860A CZ294328B6 (cs) 2002-08-22 2002-08-22 Biodegradabilní kompozice s prolongovaným uvolňováním biologicky aktivní látky a způsob její výroby
PCT/CZ2003/000046 WO2004017937A1 (en) 2002-08-22 2003-08-15 Biodegradable composition with prolonged release of the biological active compound and preparation thereof

Publications (1)

Publication Number Publication Date
NO20051441L true NO20051441L (no) 2005-05-20

Family

ID=31892767

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20051441A NO20051441L (no) 2002-08-22 2005-03-18 Biodegraderbar sammensetning med vedvarende frigivelse av den biologisk aktive forbindelse og fremstilling av slike

Country Status (13)

Country Link
US (1) US20050271699A1 (no)
EP (1) EP1536768B1 (no)
JP (1) JP2005537309A (no)
AT (1) ATE435645T1 (no)
AU (1) AU2003257375A1 (no)
CZ (1) CZ294328B6 (no)
DE (1) DE60328295D1 (no)
ES (1) ES2329782T3 (no)
HR (1) HRP20050160A2 (no)
NO (1) NO20051441L (no)
PL (1) PL373609A1 (no)
RU (1) RU2290950C2 (no)
WO (1) WO2004017937A1 (no)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2595859C1 (ru) * 2015-07-20 2016-08-27 Федеральное государственное бюджетное учреждение "Национальный исследовательский центр "Курчатовский институт" Полимеросодержащее лекарственное средство на основе противоопухолевого препарата этопозида

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3716302C2 (de) * 1987-05-15 1996-02-01 Henkel Kgaa Verbesserte resorbierbare Knochenwachse und ihre Verwendung
DE3825211A1 (de) * 1988-07-25 1990-02-01 Henkel Kgaa Verbesserte koerperresorbierbare knochenwachse (iii)
DE69030786T2 (de) * 1989-01-27 1998-02-19 Mitsui Toatsu Chemicals Verfahren zur herstellung eines bioverträglichen polyesters
PT99345A (pt) * 1990-10-30 1992-09-30 Alza Corp Processo para a preparacao de sistemas apropriados para a libertacao de agentes terapeuticos
DE4112464A1 (de) * 1991-04-17 1992-10-22 Henkel Kgaa Verbesserte retard-systeme fuer die zeitverzoegerte freigabe medizinischer und/oder biologischer wertstoffe aus einem depot-traegermaterial
CZ282292B6 (cs) * 1995-02-24 1997-06-11 Odbor Správy Majetku Mo Farmaceutický antimikrobiální přípravek
US5869079A (en) * 1995-06-02 1999-02-09 Oculex Pharmaceuticals, Inc. Formulation for controlled release of drugs by combining hydrophilic and hydrophobic agents
DE19858891A1 (de) * 1998-12-19 2000-06-21 Merck Patent Gmbh Verbesserte Knochensiegel
NZ523385A (en) * 2000-06-28 2005-09-30 Atul J Biodegradable vehicles and BAS-loaded delivery systems for use as biodegradable fillers and/or spacers, e.g. artificial skin
IL140017A (en) * 2000-11-30 2009-09-22 Abraham J Domb Polyhedra

Also Published As

Publication number Publication date
CZ294328B6 (cs) 2004-11-10
EP1536768B1 (en) 2009-07-08
HRP20050160A2 (en) 2005-04-30
RU2290950C2 (ru) 2007-01-10
ATE435645T1 (de) 2009-07-15
EP1536768A1 (en) 2005-06-08
PL373609A1 (en) 2005-09-05
RU2005107795A (ru) 2005-08-10
US20050271699A1 (en) 2005-12-08
WO2004017937A1 (en) 2004-03-04
AU2003257375A1 (en) 2004-03-11
CZ20022860A3 (cs) 2004-04-14
DE60328295D1 (de) 2009-08-20
JP2005537309A (ja) 2005-12-08
ES2329782T3 (es) 2009-12-01

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