ATE527000T1 - Bioabbaubares polymersystem - Google Patents

Bioabbaubares polymersystem

Info

Publication number
ATE527000T1
ATE527000T1 AT02735663T AT02735663T ATE527000T1 AT E527000 T1 ATE527000 T1 AT E527000T1 AT 02735663 T AT02735663 T AT 02735663T AT 02735663 T AT02735663 T AT 02735663T AT E527000 T1 ATE527000 T1 AT E527000T1
Authority
AT
Austria
Prior art keywords
biodegradable polymer
polymer system
anhydride
inclusion
degradation
Prior art date
Application number
AT02735663T
Other languages
English (en)
Inventor
John Rose
Steven Hardwick
Original Assignee
Smith & Nephew
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith & Nephew filed Critical Smith & Nephew
Application granted granted Critical
Publication of ATE527000T1 publication Critical patent/ATE527000T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58Materials at least partially resorbable by the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/06At least partially resorbable materials
    • A61L17/10At least partially resorbable materials containing macromolecular materials
    • A61L17/12Homopolymers or copolymers of glycolic acid or lactic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/26Mixtures of macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/0401Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/06Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
    • A61B17/06166Sutures
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/72Intramedullary pins, nails or other devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/80Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/80Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
    • A61B17/8061Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates specially adapted for particular bones
    • A61B17/8071Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates specially adapted for particular bones for the jaw
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/84Fasteners therefor or fasteners being internal fixation devices
    • A61B17/86Pins or screws or threaded wires; nuts therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/84Fasteners therefor or fasteners being internal fixation devices
    • A61B17/86Pins or screws or threaded wires; nuts therefor
    • A61B17/866Material or manufacture
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00004(bio)absorbable, (bio)resorbable or resorptive
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0014Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
    • A61F2250/003Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in adsorbability or resorbability, i.e. in adsorption or resorption time

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Materials Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Composite Materials (AREA)
  • Materials For Medical Uses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Biological Depolymerization Polymers (AREA)
AT02735663T 2001-07-04 2002-07-03 Bioabbaubares polymersystem ATE527000T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0116341.9A GB0116341D0 (en) 2001-07-04 2001-07-04 Biodegradable polymer systems
PCT/GB2002/003072 WO2003004071A1 (en) 2001-07-04 2002-07-03 Biodegradable polymer systems

Publications (1)

Publication Number Publication Date
ATE527000T1 true ATE527000T1 (de) 2011-10-15

Family

ID=9917916

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02735663T ATE527000T1 (de) 2001-07-04 2002-07-03 Bioabbaubares polymersystem

Country Status (9)

Country Link
US (1) US7524891B2 (de)
EP (1) EP1401510B1 (de)
JP (1) JP2004533308A (de)
AT (1) ATE527000T1 (de)
AU (1) AU2002310552B2 (de)
CA (1) CA2452358C (de)
ES (1) ES2374555T3 (de)
GB (1) GB0116341D0 (de)
WO (1) WO2003004071A1 (de)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0317192D0 (en) * 2003-07-19 2003-08-27 Smith & Nephew High strength bioresorbable co-polymers
GB0329654D0 (en) * 2003-12-23 2004-01-28 Smith & Nephew Tunable segmented polyacetal
CA2619571A1 (en) * 2005-08-18 2007-02-22 Smith & Nephew, Plc High strength devices and composites
CA2619552A1 (en) * 2005-08-18 2007-02-22 Smith & Nephew, Plc Multimodal high strength devices and composites
US9849216B2 (en) 2006-03-03 2017-12-26 Smith & Nephew, Inc. Systems and methods for delivering a medicament
US7794495B2 (en) * 2006-07-17 2010-09-14 Advanced Cardiovascular Systems, Inc. Controlled degradation of stents
US8394488B2 (en) 2006-10-06 2013-03-12 Cordis Corporation Bioabsorbable device having composite structure for accelerating degradation
US8828419B2 (en) * 2006-10-06 2014-09-09 Cordis Corporation Bioabsorbable device having encapsulated additives for accelerating degradation
US20080177330A1 (en) * 2006-10-24 2008-07-24 Ralph James D Self-locking screws for medical implants
US20080103584A1 (en) * 2006-10-25 2008-05-01 Biosensors International Group Temporal Intraluminal Stent, Methods of Making and Using
CA2679365C (en) * 2006-11-30 2016-05-03 Smith & Nephew, Inc. Fiber reinforced composite material
JP5416090B2 (ja) 2007-04-18 2014-02-12 スミス アンド ネフュー ピーエルシー 形状記憶ポリマーの膨張成形
EP2150288B1 (de) 2007-04-19 2011-04-13 Smith & Nephew, Inc. Graft-fixierung
US20100069547A1 (en) * 2007-04-19 2010-03-18 Smith & Nephew, Inc. Shape Memory Polymers Containing Degradation Accelerant
EP2142227B1 (de) 2007-04-19 2012-02-29 Smith & Nephew, Inc. Multimodale formgedächtnis-polymere
GB0715376D0 (en) * 2007-08-07 2007-09-19 Smith & Nephew Coating
GB0813659D0 (en) 2008-07-25 2008-09-03 Smith & Nephew Fracture putty
GB0819296D0 (en) * 2008-10-21 2008-11-26 Smith & Nephew Coating II
CA2794019C (en) 2009-03-24 2019-09-10 Stabiliz Orthopedics, LLC Orthopedic fixation device with bioresorbable layer
US9889238B2 (en) * 2009-07-21 2018-02-13 Abbott Cardiovascular Systems Inc. Biodegradable stent with adjustable degradation rate
US8889823B2 (en) 2009-07-21 2014-11-18 Abbott Cardiovascular Systems Inc. Method to make poly(L-lactide) stent with tunable degradation rate
US8506593B2 (en) 2010-04-11 2013-08-13 Lap IP, Inc Implantable biodegradable wound closure device and method
US20120009420A1 (en) 2010-07-07 2012-01-12 Lifoam Industries Compostable or Biobased Foams
US8962706B2 (en) 2010-09-10 2015-02-24 Lifoam Industries, Llc Process for enabling secondary expansion of expandable beads
US10525169B2 (en) 2010-10-20 2020-01-07 206 Ortho, Inc. Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications
US11058796B2 (en) 2010-10-20 2021-07-13 206 Ortho, Inc. Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications
US11291483B2 (en) 2010-10-20 2022-04-05 206 Ortho, Inc. Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants
US20120101593A1 (en) 2010-10-20 2012-04-26 BIOS2 Medical, Inc. Implantable polymer for bone and vascular lesions
US11484627B2 (en) 2010-10-20 2022-11-01 206 Ortho, Inc. Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications
WO2015095745A1 (en) 2010-10-20 2015-06-25 206 Ortho, Inc. Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications
US11207109B2 (en) 2010-10-20 2021-12-28 206 Ortho, Inc. Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications
CN102030889A (zh) * 2010-11-18 2011-04-27 江南大学 一种光响应型聚酯
CN102093540A (zh) * 2010-11-18 2011-06-15 江南大学 一种蓖麻油酸基弹性体
US8834776B2 (en) 2011-05-10 2014-09-16 Abbott Cardiovascular Systems Inc. Control of degradation profile of bioabsorbable poly(l-lactide) scaffold
EP2819620A4 (de) 2012-02-29 2015-11-04 206 Ortho Inc Verfahren und vorrichtung zur behandlung von knochenbrüchen unter verwendung von zusammengesetzten implantaten
US10675376B2 (en) 2012-05-24 2020-06-09 Ethicon Llc Mechanically strong absorbable polymeric blend compositions of precisely controllable absorption rates, processing methods, and products therefrom
CN104919022B (zh) * 2013-01-18 2016-07-27 株式会社吴羽 坑井处理液材料以及含有该坑井处理液材料的坑井处理液
AU2014268380B2 (en) 2013-05-23 2019-06-27 206 Ortho, Inc. Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants
KR20160091960A (ko) 2013-11-27 2016-08-03 에티컨, 엘엘씨 정밀하게 제어가능한 흡수 속도를 갖는 흡수성 중합체 블렌드 조성물, 가공 방법, 및 그로부터의 치수 안정한 의료 장치

Family Cites Families (135)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3531561A (en) 1965-04-20 1970-09-29 Ethicon Inc Suture preparation
BE758156R (fr) 1970-05-13 1971-04-28 Ethicon Inc Element de suture absorbable et sa
US3797499A (en) 1970-05-13 1974-03-19 Ethicon Inc Polylactide fabric graphs for surgical implantation
US3736646A (en) 1971-10-18 1973-06-05 American Cyanamid Co Method of attaching surgical needles to multifilament polyglycolic acid absorbable sutures
US4137921A (en) 1977-06-24 1979-02-06 Ethicon, Inc. Addition copolymers of lactide and glycolide and method of preparation
US4181983A (en) 1977-08-29 1980-01-08 Kulkarni R K Assimilable hydrophilic prosthesis
US5110852A (en) 1982-07-16 1992-05-05 Rijksuniversiteit Te Groningen Filament material polylactide mixtures
US4700704A (en) 1982-10-01 1987-10-20 Ethicon, Inc. Surgical articles of copolymers of glycolide and ε-caprolactone and methods of producing the same
US4523591A (en) 1982-10-22 1985-06-18 Kaplan Donald S Polymers for injection molding of absorbable surgical devices
US4539981A (en) 1982-11-08 1985-09-10 Johnson & Johnson Products, Inc. Absorbable bone fixation device
US4438253A (en) 1982-11-12 1984-03-20 American Cyanamid Company Poly(glycolic acid)/poly(alkylene glycol) block copolymers and method of manufacturing the same
US4643734A (en) * 1983-05-05 1987-02-17 Hexcel Corporation Lactide/caprolactone polymer, method of making the same, composites thereof, and prostheses produced therefrom
US4636215A (en) 1984-01-11 1987-01-13 Rei, Inc. Combination tray and condylar prosthesis for mandibular reconstruction and the like
US4990161A (en) 1984-03-16 1991-02-05 Kampner Stanley L Implant with resorbable stem
US4840632A (en) 1984-03-16 1989-06-20 Kampner Stanley L Hip prosthesis
US4559945A (en) 1984-09-21 1985-12-24 Ethicon, Inc. Absorbable crystalline alkylene malonate copolyesters and surgical devices therefrom
US4776329A (en) 1985-09-20 1988-10-11 Richards Medical Company Resorbable compressing screw and method
US6005161A (en) 1986-01-28 1999-12-21 Thm Biomedical, Inc. Method and device for reconstruction of articular cartilage
FI81498C (fi) 1987-01-13 1990-11-12 Biocon Oy Kirurgiska material och instrument.
US5527337A (en) * 1987-06-25 1996-06-18 Duke University Bioabsorbable stent and method of making the same
JP2561853B2 (ja) 1988-01-28 1996-12-11 株式会社ジェイ・エム・エス 形状記憶性を有する成形体及びその使用方法
US4858603A (en) 1988-06-06 1989-08-22 Johnson & Johnson Orthopaedics, Inc. Bone pin
US5502158A (en) 1988-08-08 1996-03-26 Ecopol, Llc Degradable polymer composition
US5444113A (en) 1988-08-08 1995-08-22 Ecopol, Llc End use applications of biodegradable polymers
JPH0739506B2 (ja) 1988-09-30 1995-05-01 三菱重工業株式会社 形状記憶ポリマー発泡体
US4938763B1 (en) 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
US5633002A (en) 1988-10-04 1997-05-27 Boehringer Ingelheim Gmbh Implantable, biodegradable system for releasing active substance
FI85223C (fi) 1988-11-10 1992-03-25 Biocon Oy Biodegraderande kirurgiska implant och medel.
FR2641692A1 (fr) 1989-01-17 1990-07-20 Nippon Zeon Co Bouchon de fermeture d'une breche pour application medicale et dispositif pour bouchon de fermeture l'utilisant
US5522817A (en) 1989-03-31 1996-06-04 United States Surgical Corporation Absorbable surgical fastener with bone penetrating elements
US5108755A (en) 1989-04-27 1992-04-28 Sri International Biodegradable composites for internal medical use
US5294395A (en) 1989-09-01 1994-03-15 Ethicon, Inc. Thermal treatment of theraplastic filaments for the preparation of surgical sutures
EP0444197B1 (de) 1989-09-15 1994-08-03 Nauchno-Proizvodstvennoe Obiedinenie Komplexnogo Razvitia Meditsinskoi Tekhniki I Izdely Meditsinskogo Naznachenia "Ekran" Endoprothese des hüftgelenks
US6908466B1 (en) * 1990-06-28 2005-06-21 Bonutti Ip, Llc Surgical devices having a biodegradable material with a therapeutic agent
IL94910A (en) 1990-06-29 1994-04-12 Technion Research Dev Foundati Biomedical adhesive compositions
US5201738A (en) 1990-12-10 1993-04-13 Johnson & Johnson Orthopaedics, Inc. Biodegradable biocompatible anti-displacement device for prosthetic bone joints
CA2062012C (en) 1991-03-05 2003-04-29 Randall D. Ross Bioabsorbable interference bone fixation screw
EP0520177B1 (de) 1991-05-24 1995-12-13 Synthes AG, Chur Resorbierbare Sehnen- und Knochenverstärkungseinrichtung
EP0523926A3 (en) 1991-07-15 1993-12-01 Smith & Nephew Richards Inc Prosthetic implants with bioabsorbable coating
US5275601A (en) 1991-09-03 1994-01-04 Synthes (U.S.A) Self-locking resorbable screws and plates for internal fixation of bone fractures and tendon-to-bone attachment
US5500013A (en) 1991-10-04 1996-03-19 Scimed Life Systems, Inc. Biodegradable drug delivery vascular stent
US5360448A (en) 1991-10-07 1994-11-01 Thramann Jeffrey J Porous-coated bone screw for securing prosthesis
US5383931A (en) 1992-01-03 1995-01-24 Synthes (U.S.A.) Resorbable implantable device for the reconstruction of the orbit of the human skull
FI95537C (fi) 1992-01-24 1996-02-26 Biocon Oy Kirurginen implantti
CA2130083A1 (en) 1992-02-14 1993-08-19 Acufex Microsurgical, Inc. Polymeric screws and coatings for surgical uses
US5333624A (en) 1992-02-24 1994-08-02 United States Surgical Corporation Surgical attaching apparatus
US5571193A (en) 1992-03-12 1996-11-05 Kampner; Stanley L. Implant with reinforced resorbable stem
AU4381793A (en) 1992-05-20 1993-12-13 Cytrx Corporation Gel composition for implant prosthesis and method of use
DK0615555T3 (da) * 1992-10-02 2001-07-09 Cargill Inc Tekstilmateriale af smeltestabil lactidpolymer og fremgangsmåde til fremstilling deraf
US5263991A (en) 1992-10-21 1993-11-23 Biomet, Inc. Method for heating biocompatible implants in a thermal packaging line
US5437918A (en) 1992-11-11 1995-08-01 Mitsui Toatsu Chemicals, Inc. Degradable non-woven fabric and preparation process thereof
FR2701214B1 (fr) 1993-02-08 1998-07-31 Nippon Zeon Co Cathéter et procédé de fabrication de celui-ci.
US5441515A (en) 1993-04-23 1995-08-15 Advanced Cardiovascular Systems, Inc. Ratcheting stent
US5716410A (en) 1993-04-30 1998-02-10 Scimed Life Systems, Inc. Temporary stent and method of use
US6315788B1 (en) 1994-02-10 2001-11-13 United States Surgical Corporation Composite materials and surgical articles made therefrom
US5417712A (en) 1994-02-17 1995-05-23 Mitek Surgical Products, Inc. Bone anchor
US5626861A (en) 1994-04-01 1997-05-06 Massachusetts Institute Of Technology Polymeric-hydroxyapatite bone composite
US6001101A (en) 1994-07-05 1999-12-14 Depuy France Screw device with threaded head for permitting the coaptation of two bone fragments
DE4424883A1 (de) 1994-07-14 1996-01-18 Merck Patent Gmbh Femurprothese
US5837276A (en) 1994-09-02 1998-11-17 Delab Apparatus for the delivery of elongate solid drug compositions
US5690671A (en) 1994-12-13 1997-11-25 Micro Interventional Systems, Inc. Embolic elements and methods and apparatus for their delivery
US5634936A (en) 1995-02-06 1997-06-03 Scimed Life Systems, Inc. Device for closing a septal defect
DE59608020D1 (de) 1995-08-16 2001-11-29 Frank Lampe Endoprothese, insbesondere hüftgelenkprothese
FI98136C (fi) 1995-09-27 1997-04-25 Biocon Oy Kudosolosuhteissa hajoava materiaali ja menetelmä sen valmistamiseksi
US6113624A (en) 1995-10-02 2000-09-05 Ethicon, Inc. Absorbable elastomeric polymer
US5716413A (en) 1995-10-11 1998-02-10 Osteobiologics, Inc. Moldable, hand-shapable biodegradable implant material
JP3731838B2 (ja) 1996-04-30 2006-01-05 株式会社クレハ ポリグリコール酸配向フィルム及びその製造方法
US6143948A (en) 1996-05-10 2000-11-07 Isotis B.V. Device for incorporation and release of biologically active agents
US5670161A (en) 1996-05-28 1997-09-23 Healy; Kevin E. Biodegradable stent
CA2252860C (en) 1996-05-28 2011-03-22 1218122 Ontario Inc. Resorbable implant biomaterial made of condensed calcium phosphate particles
US5935172A (en) 1996-06-28 1999-08-10 Johnson & Johnson Professional, Inc. Prosthesis with variable fit and strain distribution
US5756651A (en) 1996-07-17 1998-05-26 Chronopol, Inc. Impact modified polylactide
JP4425993B2 (ja) 1996-08-23 2010-03-03 オステオバイオロジックス, インコーポレイテッド 把持型物質テスタ
US5893850A (en) 1996-11-12 1999-04-13 Cachia; Victor V. Bone fixation device
WO1998024483A2 (en) * 1996-12-03 1998-06-11 Osteobiologics, Inc. Biodegradable polymeric film
US5733330A (en) 1997-01-13 1998-03-31 Advanced Cardiovascular Systems, Inc. Balloon-expandable, crush-resistant locking stent
SE512050C2 (sv) 1997-01-21 2000-01-17 Nobel Biocare Ab Rotationssymmetriskt benförankringselement
US5997580A (en) 1997-03-27 1999-12-07 Johnson & Johnson Professional, Inc. Cement restrictor including shape memory material
US5810821A (en) 1997-03-28 1998-09-22 Biomet Inc. Bone fixation screw system
US5977204A (en) 1997-04-11 1999-11-02 Osteobiologics, Inc. Biodegradable implant material comprising bioactive ceramic
DE69840171D1 (de) * 1997-05-30 2008-12-11 Osteobiologics Inc Faserverstärkte,poröse,biologisch abbaubare implantatvorrichtung
US5980564A (en) 1997-08-01 1999-11-09 Schneider (Usa) Inc. Bioabsorbable implantable endoprosthesis with reservoir
US6001100A (en) 1997-08-19 1999-12-14 Bionx Implants Oy Bone block fixation implant
US6013080A (en) 1997-10-30 2000-01-11 Johnson & Johnson Professional, Inc. Tamp with horizontal steps used for impaction bone grafting in revision femur
SE510868C2 (sv) 1997-11-03 1999-07-05 Artimplant Dev Artdev Ab Formkroppar för användning som implantat i humanmedicin samt förfarande för framställning av sådana formkroppar
US6150497A (en) 1998-01-14 2000-11-21 Sherwood Services Ag Method for the production of polyglycolic acid
CA2316190C (en) 1998-02-23 2005-09-13 Massachusetts Institute Of Technology Biodegradable shape memory polymers
US20020022588A1 (en) * 1998-06-23 2002-02-21 James Wilkie Methods and compositions for sealing tissue leaks
US6248430B1 (en) * 1998-08-11 2001-06-19 Dainippon Ink And Chemicals, Inc. Lactic acid-based polymer laminated product and molded product
JP2000117920A (ja) * 1998-08-11 2000-04-25 Dainippon Ink & Chem Inc 乳酸系ポリマ―積層体及び成形物
SE515572C2 (sv) 1998-09-09 2001-09-03 Lanka Ltd Implantat, sätt att framställa det och användning av det
JP2000085054A (ja) * 1998-09-14 2000-03-28 Daicel Chem Ind Ltd 崩壊性積層体およびその製造方法
US6248108B1 (en) 1998-09-30 2001-06-19 Bionx Implants Oy Bioabsorbable surgical screw and washer system
US6162225A (en) 1998-10-26 2000-12-19 Musculoskeletal Transplant Foundation Allograft bone fixation screw method and apparatus
EP1000958B1 (de) 1998-11-12 2004-03-17 Takiron Co. Ltd. Bioabbaubares, absorbierbares Formgedächtnismaterial
US6283973B1 (en) 1998-12-30 2001-09-04 Depuy Orthopaedics, Inc. Strength fixation device
US6147135A (en) 1998-12-31 2000-11-14 Ethicon, Inc. Fabrication of biocompatible polymeric composites
US6293950B1 (en) 1999-01-15 2001-09-25 Luitpold Pharmaceuticals, Inc. Resorbable pin systems
CA2360904C (en) * 1999-02-04 2007-05-22 Michael Ahrens Bone screw
US6206883B1 (en) * 1999-03-05 2001-03-27 Stryker Technologies Corporation Bioabsorbable materials and medical devices made therefrom
US6187008B1 (en) 1999-07-07 2001-02-13 Bristol-Myers Squibb Device for temporarily fixing bones
US7033603B2 (en) * 1999-08-06 2006-04-25 Board Of Regents The University Of Texas Drug releasing biodegradable fiber for delivery of therapeutics
DE59901090D1 (de) * 1999-12-23 2002-05-02 Storz Karl Gmbh & Co Kg Schraube mit dezentralem Antrieb
US6423062B2 (en) 2000-02-18 2002-07-23 Albert Enayati Bioabsorbable pin for external bone fixation
US6425923B1 (en) 2000-03-07 2002-07-30 Zimmer, Inc. Contourable polymer filled implant
US6468277B1 (en) 2000-04-04 2002-10-22 Ethicon, Inc. Orthopedic screw and method
NZ523385A (en) * 2000-06-28 2005-09-30 Atul J Biodegradable vehicles and BAS-loaded delivery systems for use as biodegradable fillers and/or spacers, e.g. artificial skin
WO2002013701A1 (en) * 2000-08-17 2002-02-21 Tyco Healthcare Group Lp Sutures and coatings made from therapeutic absorbable glass
US6605090B1 (en) * 2000-10-25 2003-08-12 Sdgi Holdings, Inc. Non-metallic implant devices and intra-operative methods for assembly and fixation
US6719935B2 (en) * 2001-01-05 2004-04-13 Howmedica Osteonics Corp. Process for forming bioabsorbable implants
US6471707B1 (en) 2001-05-11 2002-10-29 Biomet Bone screw having bioresorbable proximal shaft portion
US6749639B2 (en) * 2001-08-27 2004-06-15 Mayo Foundation For Medical Education And Research Coated prosthetic implant
US6841111B2 (en) * 2001-08-31 2005-01-11 Basf Corporation Method for making a polyurea-polyurethane composite structure substantially free of volatile organic compounds
US6916321B2 (en) * 2001-09-28 2005-07-12 Ethicon, Inc. Self-tapping resorbable two-piece bone screw
US20030125745A1 (en) * 2001-11-05 2003-07-03 Bio One Tech Inc. Bone-fixing device
AU2002364107B2 (en) * 2001-12-21 2008-09-25 Smith & Nephew, Inc. Hinged joint system
GB0202233D0 (en) * 2002-01-31 2002-03-20 Smith & Nephew Bioresorbable polymers
WO2003080119A1 (en) * 2002-03-26 2003-10-02 Yissum Research Development Company Of The Hebrew University Of Jerusalem Responsive biomedical composites
US7261734B2 (en) * 2002-04-23 2007-08-28 Boston Scientific Scimed, Inc. Resorption-controllable medical implants
US6981991B2 (en) * 2002-06-27 2006-01-03 Ferree Bret A Arthroplasty devices configured to reduce shear stress
NZ540697A (en) * 2002-12-12 2008-05-30 Osteotech Inc Formable and settable polymer bone composite and method of production thereof
EP1433489A1 (de) * 2002-12-23 2004-06-30 Degradable Solutions AG Biologisch abbaubares, poröses Knochenimplantat mit integrierter Abdeckmembrane
EP1592728A2 (de) * 2003-01-16 2005-11-09 Carnegie-Mellon University Biologisch abbaubare polyurethane und verwendung davon
US20040156878A1 (en) * 2003-02-11 2004-08-12 Alireza Rezania Implantable medical device seeded with mammalian cells and methods of treatment
US20070043376A1 (en) * 2003-02-21 2007-02-22 Osteobiologics, Inc. Bone and cartilage implant delivery device
JP4251061B2 (ja) * 2003-10-03 2009-04-08 ブリヂストンスポーツ株式会社 ゴルフクラブヘッド
JP2007517635A (ja) * 2004-01-16 2007-07-05 オステオバイオロジックス, インコーポレイテッド 骨−腱−骨インプラント
EP1729674A4 (de) * 2004-02-05 2011-01-26 Osteobiologics Inc Saugfähige orthopädische implantate
US20060067971A1 (en) * 2004-09-27 2006-03-30 Story Brooks J Bone void filler
JP2008521560A (ja) * 2004-11-30 2008-06-26 オステオバイオロジクス・インコーポレーテッド 関節面の欠損を治療するためのインプラント及びそのデリバリーシステム
US7772352B2 (en) * 2005-01-28 2010-08-10 Bezwada Biomedical Llc Bioabsorbable and biocompatible polyurethanes and polyamides for medical devices
JP4796079B2 (ja) * 2005-02-01 2011-10-19 オステオバイオロジクス・インコーポレーテッド 多相インプラントへ生物活性剤を選択的に添加するための方法及び装置
US7858078B2 (en) * 2005-12-06 2010-12-28 Tyco Healthcare Group Lp Bioabsorbable surgical composition
US9446226B2 (en) * 2005-12-07 2016-09-20 Ramot At Tel-Aviv University Ltd. Drug-delivering composite structures
AU2007207429A1 (en) * 2006-01-19 2007-07-26 Warsaw Orthopedic, Inc. Injectable and moldable bone substitute materials

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ES2374555T3 (es) 2012-02-17
EP1401510A1 (de) 2004-03-31
US7524891B2 (en) 2009-04-28
CA2452358C (en) 2010-05-04
EP1401510B1 (de) 2011-10-05
CA2452358A1 (en) 2003-01-16
US20040242722A1 (en) 2004-12-02
GB0116341D0 (en) 2001-08-29
JP2004533308A (ja) 2004-11-04

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