NO20050447L - Isolering og identifisering av T-celler - Google Patents
Isolering og identifisering av T-cellerInfo
- Publication number
- NO20050447L NO20050447L NO20050447A NO20050447A NO20050447L NO 20050447 L NO20050447 L NO 20050447L NO 20050447 A NO20050447 A NO 20050447A NO 20050447 A NO20050447 A NO 20050447A NO 20050447 L NO20050447 L NO 20050447L
- Authority
- NO
- Norway
- Prior art keywords
- isolation
- cells
- identification
- autologous
- cell
- Prior art date
Links
- 210000001744 T-lymphocyte Anatomy 0.000 title abstract 4
- 238000002955 isolation Methods 0.000 title 1
- 229940030156 cell vaccine Drugs 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 201000006417 multiple sclerosis Diseases 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
- G01N33/505—Cells of the immune system involving T-cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterized by the route of administration
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the dose, timing or administration schedule
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- A61K39/0005—Vertebrate antigens
- A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
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- A—HUMAN NECESSITIES
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- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
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- A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
- A61K39/4621—Cellular immunotherapy characterized by the effect or the function of the cells immunosuppressive or immunotolerising
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- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/46432—Nervous system antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/46433—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/285—Demyelinating diseases; Multipel sclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Hematology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Pathology (AREA)
- Rheumatology (AREA)
- Rehabilitation Therapy (AREA)
- Toxicology (AREA)
Abstract
Foreliggende oppfinnelse angår forbedrede autologe T-celle-vaksiner og forbedrede fremgangsmåter for fremstilling av dem. Oppfinnelsen er også rettet mot fremgangsmåter for behandling av autoimmune sykdommer som multippel sklerose eller reumatoid artritt under anvendelse av autologe T-celle-vaksiner. Oppfinnelsen er videre rettet mot diagnostisering av T-celle-tilknyttede sykdommer.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US40252102P | 2002-08-08 | 2002-08-08 | |
PCT/US2003/024548 WO2004015070A2 (en) | 2002-08-08 | 2003-08-06 | Isolation and identification of t cells |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20050447L true NO20050447L (no) | 2005-03-07 |
NO338881B1 NO338881B1 (no) | 2016-10-31 |
Family
ID=31715870
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20050447A NO338881B1 (no) | 2002-08-08 | 2005-01-26 | Fremgangsmåte for isolering av T-celler |
NO20150482A NO20150482L (no) | 2002-08-08 | 2015-04-16 | Isolering og identifisering av T-celler |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20150482A NO20150482L (no) | 2002-08-08 | 2015-04-16 | Isolering og identifisering av T-celler |
Country Status (19)
Country | Link |
---|---|
US (2) | US7695713B2 (no) |
EP (2) | EP1546719B1 (no) |
JP (2) | JP4705371B2 (no) |
KR (1) | KR100795840B1 (no) |
CN (1) | CN100567987C (no) |
AU (1) | AU2003258090B2 (no) |
BR (1) | BRPI0305769A8 (no) |
CA (2) | CA2492848C (no) |
ES (2) | ES2545736T3 (no) |
HK (1) | HK1082520A1 (no) |
IL (1) | IL166332A (no) |
MX (1) | MXPA05001044A (no) |
NO (2) | NO338881B1 (no) |
NZ (1) | NZ537816A (no) |
PL (1) | PL214283B1 (no) |
PT (2) | PT1546719E (no) |
RU (1) | RU2327487C2 (no) |
WO (1) | WO2004015070A2 (no) |
ZA (1) | ZA200500985B (no) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
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US7381535B2 (en) | 2002-07-10 | 2008-06-03 | The Board Of Trustees Of The Leland Stanford Junior | Methods and compositions for detecting receptor-ligand interactions in single cells |
EP1546719B1 (en) * | 2002-08-08 | 2015-04-01 | Baylor College Of Medicine | Isolation and identification of t cells |
ATE492563T1 (de) | 2004-11-17 | 2011-01-15 | Amgen Inc | Vollständige humane monoklonale antikörper gegen il-13 |
KR101130597B1 (ko) * | 2005-09-13 | 2012-04-02 | 다카라 바이오 가부시키가이샤 | T 세포 리셉터 및 그 리셉터를 코드하는 핵산 |
US20090221024A1 (en) * | 2006-03-02 | 2009-09-03 | Antitope Limited | T cell assays |
EP3431585A1 (en) | 2006-05-31 | 2019-01-23 | The Regents of The University of California | Cd127 expression inversely correlates with foxp3 and suppressive function of cd4+ tregs |
GB0707933D0 (en) * | 2007-04-24 | 2007-05-30 | Apitope Technology Bristol Ltd | Disease markers |
US20090062237A1 (en) * | 2007-06-15 | 2009-03-05 | Mayo Foundation For Medical Education And Research | Evaluating immune competence |
CN102223894A (zh) * | 2008-11-21 | 2011-10-19 | 迈阿密大学 | 用于产生粘膜和系统免疫的hiv/siv疫苗 |
JP5829606B2 (ja) * | 2009-06-29 | 2015-12-09 | カリフォルニア・インスティテュート・オブ・テクノロジーCalifornia Institute Oftechnology | 単一細胞からの未知の再配列されたt細胞受容体の単離 |
WO2011080349A1 (en) * | 2010-01-04 | 2011-07-07 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Detection method of anti-myelin autoreactive t-cells and diagnostic method of autoimmune disease |
WO2011106558A1 (en) * | 2010-02-24 | 2011-09-01 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for autoimmune disease diagnosis, prognosis, and treatment |
DE102011050550A1 (de) * | 2011-05-20 | 2012-11-22 | Wolfgang Göhde | Verfahren und Anordnung zur Quantifizierung von Untergruppen aus einer Mischpopulation von Zellen |
EP2726879B1 (en) | 2011-07-01 | 2022-10-19 | Beckman Coulter, Inc. | Requlatory t cells and methods of identifying and isolating them using cd6 -expression or the combination of cd4, cd25 and cd127 |
WO2013049727A1 (en) * | 2011-09-28 | 2013-04-04 | Cb Biotechnologies, Inc. | Identification of antigen-specific adaptive immune responses using arm-pcr and high-throughput sequencing |
FR2992427A1 (fr) * | 2012-06-20 | 2013-12-27 | Assist Publ Hopitaux De Paris | Methode de pronostic d'un lymphome et kit pour sa mise en oeuvre |
IN2015KN00073A (no) * | 2012-06-27 | 2015-07-31 | Univ Rutgers | |
GB201300684D0 (en) | 2013-01-15 | 2013-02-27 | Apitope Int Nv | Peptide |
JP6508873B2 (ja) * | 2014-01-20 | 2019-05-08 | 国立大学法人富山大学 | 抗原特異的t細胞受容体の取得方法 |
EP3345000B1 (en) | 2015-08-31 | 2022-08-31 | Cedars-Sinai Medical Center | Novel blood cell biomarker for late onset alzheimer's disease |
AU2016321015B2 (en) * | 2015-09-11 | 2021-09-30 | Astellas Pharma Inc. | Method for producing renal progenitor cells |
BR112018072305A2 (pt) | 2016-05-25 | 2019-02-12 | The Council Of The Queensland Institute Of Medical Research | métodos de imunoterapia |
AU2017290119A1 (en) * | 2016-06-28 | 2019-01-24 | Geneius Biotechnology, Inc. | T cell compositions for immunotherapy |
BR112019014406A2 (pt) * | 2017-01-20 | 2020-04-28 | Atara Biotherapeutics Inc | métodos de tratar esclerose múltipla usando células t autólogas |
JP7193054B2 (ja) * | 2017-06-14 | 2022-12-20 | シンガポール ヘルス サービシズ ピーティーイー. リミテッド | 自己免疫疾患の臨床転帰を評価するための方法及びキット |
US20210061875A1 (en) | 2017-12-29 | 2021-03-04 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Compositions and methods for treating autoimmune disease |
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