NO20035116D0 - 4-(fenylpiperidin-4-yliden-metyl)-benzamidderivater og deres anvendelse forbehandling av smerte, angst eller gastrointestinale forstyrrelser - Google Patents
4-(fenylpiperidin-4-yliden-metyl)-benzamidderivater og deres anvendelse forbehandling av smerte, angst eller gastrointestinale forstyrrelserInfo
- Publication number
- NO20035116D0 NO20035116D0 NO20035116A NO20035116A NO20035116D0 NO 20035116 D0 NO20035116 D0 NO 20035116D0 NO 20035116 A NO20035116 A NO 20035116A NO 20035116 A NO20035116 A NO 20035116A NO 20035116 D0 NO20035116 D0 NO 20035116D0
- Authority
- NO
- Norway
- Prior art keywords
- phenylpiperidin
- ylidene
- anxiety
- pain
- methyl
- Prior art date
Links
- TZKLMPPHEAGFJR-UHFFFAOYSA-N 4-[phenyl(piperidin-4-ylidene)methyl]benzamide Chemical class C1=CC(C(=O)N)=CC=C1C(C=1C=CC=CC=1)=C1CCNCC1 TZKLMPPHEAGFJR-UHFFFAOYSA-N 0.000 title 1
- 208000019901 Anxiety disease Diseases 0.000 title 1
- 208000018522 Gastrointestinal disease Diseases 0.000 title 1
- 208000027520 Somatoform disease Diseases 0.000 title 1
- 230000036506 anxiety Effects 0.000 title 1
- 230000036407 pain Effects 0.000 title 1
- 208000027753 pain disease Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0101765A SE0101765D0 (sv) | 2001-05-18 | 2001-05-18 | Novel compounds |
| PCT/SE2002/000953 WO2002094812A1 (en) | 2001-05-18 | 2002-05-16 | 4-(phenyl-piperidin-4-ylidene-methyl)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20035116D0 true NO20035116D0 (no) | 2003-11-17 |
Family
ID=20284168
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20035116A NO20035116D0 (no) | 2001-05-18 | 2003-11-17 | 4-(fenylpiperidin-4-yliden-metyl)-benzamidderivater og deres anvendelse forbehandling av smerte, angst eller gastrointestinale forstyrrelser |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US7074808B2 (enExample) |
| EP (1) | EP1395576B1 (enExample) |
| JP (1) | JP2005510457A (enExample) |
| KR (1) | KR20040000467A (enExample) |
| CN (1) | CN1509282A (enExample) |
| AR (1) | AR035973A1 (enExample) |
| AT (1) | ATE303379T1 (enExample) |
| BG (1) | BG108326A (enExample) |
| BR (1) | BR0209676A (enExample) |
| CA (1) | CA2446332A1 (enExample) |
| CO (1) | CO5611136A2 (enExample) |
| CZ (1) | CZ20033085A3 (enExample) |
| DE (1) | DE60205894T2 (enExample) |
| EE (1) | EE200300540A (enExample) |
| HU (1) | HUP0401096A2 (enExample) |
| IL (1) | IL158704A0 (enExample) |
| IS (1) | IS7026A (enExample) |
| MX (1) | MXPA03010439A (enExample) |
| NO (1) | NO20035116D0 (enExample) |
| PL (1) | PL366640A1 (enExample) |
| RU (1) | RU2003131970A (enExample) |
| SE (1) | SE0101765D0 (enExample) |
| SK (1) | SK13952003A3 (enExample) |
| WO (1) | WO2002094812A1 (enExample) |
| ZA (1) | ZA200308633B (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ539828A (en) | 2001-05-18 | 2007-01-26 | Astrazeneca Ab | 4 (phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders |
| SE0203303D0 (sv) | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
| SE0203300D0 (sv) | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
| SE0300103D0 (sv) * | 2003-01-16 | 2003-01-16 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof |
| SE0300104D0 (sv) * | 2003-01-16 | 2003-01-16 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof |
| RU2005136524A (ru) * | 2003-05-16 | 2006-06-27 | Астразенека Аб (Se) | Производные диарилметилиденпиперидина, способы их получения и их применение |
| SE0301442D0 (sv) * | 2003-05-16 | 2003-05-16 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations therof and uses thereof |
| US7589103B2 (en) * | 2003-06-27 | 2009-09-15 | Janssen Pharmaceutica N.V. | Tricyclic-bridged piperidinylidene derivatives as 8-opioid modulators |
| KR20140015122A (ko) | 2003-10-01 | 2014-02-06 | 아돌로 코포레이션 | 스피로시클릭 헤테로시클릭 유도체 및 이의 사용 방법 |
| SE0400027D0 (sv) * | 2004-01-09 | 2004-01-09 | Astrazeneca Ab | Diarylmethyl piperazine derivatives, preparations thereof and uses thereof |
| SE0400026D0 (sv) * | 2004-01-09 | 2004-01-09 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof |
| SE0400025D0 (sv) * | 2004-01-09 | 2004-01-09 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof |
| KR101234421B1 (ko) | 2004-08-02 | 2013-02-18 | 아스트라제네카 아베 | 디아릴메틸 피페라진 유도체, 이의 제조 방법 및 용도 |
| US7598261B2 (en) | 2005-03-31 | 2009-10-06 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
| CN101389623A (zh) * | 2006-02-28 | 2009-03-18 | 阿斯利康(瑞典)有限公司 | 吲哚衍生物的新的盐及其在医药中的用途 |
| US7576207B2 (en) | 2006-04-06 | 2009-08-18 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
| WO2008033299A2 (en) | 2006-09-12 | 2008-03-20 | Adolor Corporation | Use of n-containing spirocompounds for the enhancement of cognitive function |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2898339A (en) | 1957-07-29 | 1959-08-04 | Wm S Merrell Co | N-substituted benzhydrol, benzhydryl, and benzhydrylidene piperidine |
| US4581171A (en) | 1983-07-27 | 1986-04-08 | Janssen Pharmaceutica, N.V. | [[Bis(aryl)methylene]-1-piperidinyl]alkyl-pyrimidinones useful for treating psychotropic disorders |
| US4816586A (en) | 1987-07-29 | 1989-03-28 | Regents Of The University Of Minnesota | Delta opioid receptor antagonists |
| US5140029A (en) | 1989-01-09 | 1992-08-18 | Janssen Pharmaceutica N.V. | 2-aminopyrimidinone derivatives |
| US4939137A (en) | 1989-06-28 | 1990-07-03 | Ortho Pharmaceutical Corporation | Ring-fused thienopyrimidinedione derivatives |
| US5683998A (en) | 1991-04-23 | 1997-11-04 | Toray Industries, Inc. | Tricyclic triazolo derivatives, processes for producing the same and the uses of the same |
| US5574159A (en) | 1992-02-03 | 1996-11-12 | Delta Pharmaceuticals, Inc. | Opioid compounds and methods for making therefor |
| GB9202238D0 (en) | 1992-02-03 | 1992-03-18 | Wellcome Found | Compounds |
| SE9504661D0 (sv) | 1995-12-22 | 1995-12-22 | Astra Pharma Inc | New compounds |
| TW548271B (en) | 1996-12-20 | 2003-08-21 | Astra Pharma Inc | Novel piperidine derivatives having an exocyclic double bond with analgesic effects |
| CA2316341A1 (en) | 1997-12-24 | 1999-07-08 | Ortho-Mcneil Pharmaceutical, Inc. | 4-[aryl(piperidin-4-yl)] aminobenzamides which bind to the delta-opioid receptor |
| US6552036B2 (en) * | 2000-03-03 | 2003-04-22 | Ortho-Mcneil Pharmaceutical, Inc. | 3-(Diarylmethylene)-8-azabicyclo[3.2.1]octane derivatives |
| US6556387B1 (en) * | 2000-03-31 | 2003-04-29 | Seagate Technology Llc | Controlling mechanical response characteristics of a disc drive actuator by adjusting a fastener engaging the actuator shaft to vary axial force on the bearing assembly |
| SE0001207D0 (sv) | 2000-04-04 | 2000-04-04 | Astrazeneca Canada Inc | Novel compounds |
| SE0001208D0 (sv) | 2000-04-04 | 2000-04-04 | Astrazeneca Canada Inc | Novel compounds |
-
2001
- 2001-05-18 SE SE0101765A patent/SE0101765D0/xx unknown
-
2002
- 2002-05-16 RU RU2003131970/04A patent/RU2003131970A/ru not_active Application Discontinuation
- 2002-05-16 AR ARP020101810A patent/AR035973A1/es unknown
- 2002-05-16 KR KR10-2003-7014941A patent/KR20040000467A/ko not_active Withdrawn
- 2002-05-16 SK SK1395-2003A patent/SK13952003A3/sk unknown
- 2002-05-16 CN CNA028101952A patent/CN1509282A/zh active Pending
- 2002-05-16 AT AT02733710T patent/ATE303379T1/de not_active IP Right Cessation
- 2002-05-16 DE DE60205894T patent/DE60205894T2/de not_active Expired - Fee Related
- 2002-05-16 JP JP2002591485A patent/JP2005510457A/ja active Pending
- 2002-05-16 MX MXPA03010439A patent/MXPA03010439A/es unknown
- 2002-05-16 IL IL15870402A patent/IL158704A0/xx unknown
- 2002-05-16 CA CA002446332A patent/CA2446332A1/en not_active Abandoned
- 2002-05-16 US US10/477,821 patent/US7074808B2/en not_active Expired - Fee Related
- 2002-05-16 EP EP02733710A patent/EP1395576B1/en not_active Expired - Lifetime
- 2002-05-16 HU HU0401096A patent/HUP0401096A2/hu unknown
- 2002-05-16 CZ CZ20033085A patent/CZ20033085A3/cs unknown
- 2002-05-16 EE EEP200300540A patent/EE200300540A/xx unknown
- 2002-05-16 PL PL02366640A patent/PL366640A1/xx not_active Application Discontinuation
- 2002-05-16 WO PCT/SE2002/000953 patent/WO2002094812A1/en not_active Ceased
- 2002-05-16 BR BR0209676-5A patent/BR0209676A/pt not_active Application Discontinuation
-
2003
- 2003-11-05 ZA ZA200308633A patent/ZA200308633B/en unknown
- 2003-11-07 BG BG108326A patent/BG108326A/bg unknown
- 2003-11-11 IS IS7026A patent/IS7026A/is unknown
- 2003-11-12 CO CO03100156A patent/CO5611136A2/es not_active Application Discontinuation
- 2003-11-17 NO NO20035116A patent/NO20035116D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US7074808B2 (en) | 2006-07-11 |
| ZA200308633B (en) | 2005-02-07 |
| EE200300540A (et) | 2004-02-16 |
| CN1509282A (zh) | 2004-06-30 |
| EP1395576B1 (en) | 2005-08-31 |
| BG108326A (bg) | 2004-12-30 |
| IS7026A (is) | 2003-11-11 |
| IL158704A0 (en) | 2004-05-12 |
| WO2002094812A1 (en) | 2002-11-28 |
| DE60205894T2 (de) | 2006-06-08 |
| EP1395576A1 (en) | 2004-03-10 |
| CA2446332A1 (en) | 2002-11-28 |
| SE0101765D0 (sv) | 2001-05-18 |
| RU2003131970A (ru) | 2005-05-10 |
| PL366640A1 (en) | 2005-02-07 |
| US20040142967A1 (en) | 2004-07-22 |
| CO5611136A2 (es) | 2006-02-28 |
| ATE303379T1 (de) | 2005-09-15 |
| AR035973A1 (es) | 2004-07-28 |
| JP2005510457A (ja) | 2005-04-21 |
| SK13952003A3 (sk) | 2004-04-06 |
| DE60205894D1 (de) | 2005-10-06 |
| BR0209676A (pt) | 2004-07-27 |
| KR20040000467A (ko) | 2004-01-03 |
| HUP0401096A2 (hu) | 2004-09-28 |
| CZ20033085A3 (cs) | 2004-05-12 |
| MXPA03010439A (es) | 2004-03-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |