IS7026A - 4-(fenýl-píperidín-4-ýlíden-metýl)-bensamíðafleiður og notkun þeirra til meðhöndlunar á sársauka, kvíða eða truflunum í maga og þörmum - Google Patents
4-(fenýl-píperidín-4-ýlíden-metýl)-bensamíðafleiður og notkun þeirra til meðhöndlunar á sársauka, kvíða eða truflunum í maga og þörmumInfo
- Publication number
- IS7026A IS7026A IS7026A IS7026A IS7026A IS 7026 A IS7026 A IS 7026A IS 7026 A IS7026 A IS 7026A IS 7026 A IS7026 A IS 7026A IS 7026 A IS7026 A IS 7026A
- Authority
- IS
- Iceland
- Prior art keywords
- ylidene
- piperidin
- anxiety
- pain
- phenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0101765A SE0101765D0 (sv) | 2001-05-18 | 2001-05-18 | Novel compounds |
| PCT/SE2002/000953 WO2002094812A1 (en) | 2001-05-18 | 2002-05-16 | 4-(phenyl-piperidin-4-ylidene-methyl)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IS7026A true IS7026A (is) | 2003-11-11 |
Family
ID=20284168
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS7026A IS7026A (is) | 2001-05-18 | 2003-11-11 | 4-(fenýl-píperidín-4-ýlíden-metýl)-bensamíðafleiður og notkun þeirra til meðhöndlunar á sársauka, kvíða eða truflunum í maga og þörmum |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US7074808B2 (is) |
| EP (1) | EP1395576B1 (is) |
| JP (1) | JP2005510457A (is) |
| KR (1) | KR20040000467A (is) |
| CN (1) | CN1509282A (is) |
| AR (1) | AR035973A1 (is) |
| AT (1) | ATE303379T1 (is) |
| BG (1) | BG108326A (is) |
| BR (1) | BR0209676A (is) |
| CA (1) | CA2446332A1 (is) |
| CO (1) | CO5611136A2 (is) |
| CZ (1) | CZ20033085A3 (is) |
| DE (1) | DE60205894T2 (is) |
| EE (1) | EE200300540A (is) |
| HU (1) | HUP0401096A2 (is) |
| IL (1) | IL158704A0 (is) |
| IS (1) | IS7026A (is) |
| MX (1) | MXPA03010439A (is) |
| NO (1) | NO20035116D0 (is) |
| PL (1) | PL366640A1 (is) |
| RU (1) | RU2003131970A (is) |
| SE (1) | SE0101765D0 (is) |
| SK (1) | SK13952003A3 (is) |
| WO (1) | WO2002094812A1 (is) |
| ZA (1) | ZA200308633B (is) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0209678A (pt) | 2001-05-18 | 2004-09-14 | Astrazeneca Ab | Composto, processo para preparar e uso do mesmo, composição farmacêutica, e, métodos para o tratamento da dor e de distúrbios gastrintestinais funcionais |
| SE0203303D0 (sv) | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
| SE0203300D0 (sv) | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
| SE0300104D0 (sv) * | 2003-01-16 | 2003-01-16 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof |
| SE0300103D0 (sv) * | 2003-01-16 | 2003-01-16 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof |
| SE0301442D0 (sv) * | 2003-05-16 | 2003-05-16 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations therof and uses thereof |
| US20070099957A1 (en) * | 2003-05-16 | 2007-05-03 | Astra Zeneca Ab | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof |
| EA015491B1 (ru) * | 2003-06-27 | 2011-08-30 | Янссен Фармацевтика Н.В. | ТРИЦИКЛИЧЕСКИЕ δ-ОПИОИДНЫЕ МОДУЛЯТОРЫ |
| NZ546834A (en) | 2003-10-01 | 2010-03-26 | Adolor Corp | Spirocyclic heterocyclic derivatives and methods of their use |
| SE0400025D0 (sv) * | 2004-01-09 | 2004-01-09 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof |
| SE0400026D0 (sv) * | 2004-01-09 | 2004-01-09 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof |
| SE0400027D0 (sv) * | 2004-01-09 | 2004-01-09 | Astrazeneca Ab | Diarylmethyl piperazine derivatives, preparations thereof and uses thereof |
| DK1781631T3 (da) | 2004-08-02 | 2012-05-14 | Astrazeneca Ab | Diarylmethylpiperazinderivater, præparater dermed og anvendelser deraf |
| US7598261B2 (en) | 2005-03-31 | 2009-10-06 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
| WO2007100282A1 (en) * | 2006-02-28 | 2007-09-07 | Astrazeneca Ab | New salts of an indole derivative and their use in medicine |
| US7576207B2 (en) | 2006-04-06 | 2009-08-18 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
| AU2007294968A1 (en) | 2006-09-12 | 2008-03-20 | Adolor Corporation | Use of N-containing spirocompounds for the enhancement of cognitive function |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2898339A (en) | 1957-07-29 | 1959-08-04 | Wm S Merrell Co | N-substituted benzhydrol, benzhydryl, and benzhydrylidene piperidine |
| US4581171A (en) | 1983-07-27 | 1986-04-08 | Janssen Pharmaceutica, N.V. | [[Bis(aryl)methylene]-1-piperidinyl]alkyl-pyrimidinones useful for treating psychotropic disorders |
| US4816586A (en) | 1987-07-29 | 1989-03-28 | Regents Of The University Of Minnesota | Delta opioid receptor antagonists |
| US5140029A (en) | 1989-01-09 | 1992-08-18 | Janssen Pharmaceutica N.V. | 2-aminopyrimidinone derivatives |
| US4939137A (en) | 1989-06-28 | 1990-07-03 | Ortho Pharmaceutical Corporation | Ring-fused thienopyrimidinedione derivatives |
| US5683998A (en) | 1991-04-23 | 1997-11-04 | Toray Industries, Inc. | Tricyclic triazolo derivatives, processes for producing the same and the uses of the same |
| GB9202238D0 (en) | 1992-02-03 | 1992-03-18 | Wellcome Found | Compounds |
| US5574159A (en) | 1992-02-03 | 1996-11-12 | Delta Pharmaceuticals, Inc. | Opioid compounds and methods for making therefor |
| SE9504661D0 (sv) | 1995-12-22 | 1995-12-22 | Astra Pharma Inc | New compounds |
| TW548271B (en) * | 1996-12-20 | 2003-08-21 | Astra Pharma Inc | Novel piperidine derivatives having an exocyclic double bond with analgesic effects |
| ES2251121T3 (es) | 1997-12-24 | 2006-04-16 | Ortho-Mcneil Pharmaceutical, Inc. | (4)-aril(piperidin-4-il) aminobenzamidas que se unen al receptor opioide delta. |
| KR20030009376A (ko) * | 2000-03-03 | 2003-01-29 | 오르토-맥네일 파마슈티칼, 인코퍼레이티드 | 3-(디아릴메틸렌)-8-아자비사이클로[3.2.1]옥탄 유도체 |
| US6556387B1 (en) * | 2000-03-31 | 2003-04-29 | Seagate Technology Llc | Controlling mechanical response characteristics of a disc drive actuator by adjusting a fastener engaging the actuator shaft to vary axial force on the bearing assembly |
| SE0001207D0 (sv) | 2000-04-04 | 2000-04-04 | Astrazeneca Canada Inc | Novel compounds |
| SE0001208D0 (sv) | 2000-04-04 | 2000-04-04 | Astrazeneca Canada Inc | Novel compounds |
-
2001
- 2001-05-18 SE SE0101765A patent/SE0101765D0/xx unknown
-
2002
- 2002-05-16 BR BR0209676-5A patent/BR0209676A/pt not_active Application Discontinuation
- 2002-05-16 EP EP02733710A patent/EP1395576B1/en not_active Expired - Lifetime
- 2002-05-16 DE DE60205894T patent/DE60205894T2/de not_active Expired - Fee Related
- 2002-05-16 US US10/477,821 patent/US7074808B2/en not_active Expired - Fee Related
- 2002-05-16 KR KR10-2003-7014941A patent/KR20040000467A/ko not_active Application Discontinuation
- 2002-05-16 AT AT02733710T patent/ATE303379T1/de not_active IP Right Cessation
- 2002-05-16 RU RU2003131970/04A patent/RU2003131970A/ru not_active Application Discontinuation
- 2002-05-16 EE EEP200300540A patent/EE200300540A/xx unknown
- 2002-05-16 JP JP2002591485A patent/JP2005510457A/ja active Pending
- 2002-05-16 HU HU0401096A patent/HUP0401096A2/hu unknown
- 2002-05-16 PL PL02366640A patent/PL366640A1/xx not_active Application Discontinuation
- 2002-05-16 WO PCT/SE2002/000953 patent/WO2002094812A1/en active IP Right Grant
- 2002-05-16 CZ CZ20033085A patent/CZ20033085A3/cs unknown
- 2002-05-16 MX MXPA03010439A patent/MXPA03010439A/es unknown
- 2002-05-16 IL IL15870402A patent/IL158704A0/xx unknown
- 2002-05-16 AR ARP020101810A patent/AR035973A1/es unknown
- 2002-05-16 CN CNA028101952A patent/CN1509282A/zh active Pending
- 2002-05-16 SK SK1395-2003A patent/SK13952003A3/sk unknown
- 2002-05-16 CA CA002446332A patent/CA2446332A1/en not_active Abandoned
-
2003
- 2003-11-05 ZA ZA200308633A patent/ZA200308633B/en unknown
- 2003-11-07 BG BG108326A patent/BG108326A/bg unknown
- 2003-11-11 IS IS7026A patent/IS7026A/is unknown
- 2003-11-12 CO CO03100156A patent/CO5611136A2/es not_active Application Discontinuation
- 2003-11-17 NO NO20035116A patent/NO20035116D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE303379T1 (de) | 2005-09-15 |
| US20040142967A1 (en) | 2004-07-22 |
| BR0209676A (pt) | 2004-07-27 |
| RU2003131970A (ru) | 2005-05-10 |
| EE200300540A (et) | 2004-02-16 |
| AR035973A1 (es) | 2004-07-28 |
| CZ20033085A3 (cs) | 2004-05-12 |
| BG108326A (bg) | 2004-12-30 |
| DE60205894D1 (de) | 2005-10-06 |
| DE60205894T2 (de) | 2006-06-08 |
| JP2005510457A (ja) | 2005-04-21 |
| MXPA03010439A (es) | 2004-03-09 |
| PL366640A1 (en) | 2005-02-07 |
| SK13952003A3 (sk) | 2004-04-06 |
| HUP0401096A2 (hu) | 2004-09-28 |
| CA2446332A1 (en) | 2002-11-28 |
| NO20035116D0 (no) | 2003-11-17 |
| IL158704A0 (en) | 2004-05-12 |
| SE0101765D0 (sv) | 2001-05-18 |
| ZA200308633B (en) | 2005-02-07 |
| US7074808B2 (en) | 2006-07-11 |
| KR20040000467A (ko) | 2004-01-03 |
| CN1509282A (zh) | 2004-06-30 |
| WO2002094812A1 (en) | 2002-11-28 |
| EP1395576B1 (en) | 2005-08-31 |
| EP1395576A1 (en) | 2004-03-10 |
| CO5611136A2 (es) | 2006-02-28 |
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