NO20014864D0 - Substituerte 1,4-dihydro-inden [1,2-C] pyrazoler som inhibitorer av tyrosin kinase - Google Patents
Substituerte 1,4-dihydro-inden [1,2-C] pyrazoler som inhibitorer av tyrosin kinaseInfo
- Publication number
- NO20014864D0 NO20014864D0 NO20014864A NO20014864A NO20014864D0 NO 20014864 D0 NO20014864 D0 NO 20014864D0 NO 20014864 A NO20014864 A NO 20014864A NO 20014864 A NO20014864 A NO 20014864A NO 20014864 D0 NO20014864 D0 NO 20014864D0
- Authority
- NO
- Norway
- Prior art keywords
- pyrazoles
- inhibitors
- dihydroindene
- substituted
- tyrosine kinase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12796399P | 1999-04-06 | 1999-04-06 | |
PCT/US2000/008192 WO2000059901A1 (en) | 1999-04-06 | 2000-03-28 | Substituted 1,4-dihydroindeno[1,2-c]pyrazoles as inhibitors of tyrosine kinase |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20014864D0 true NO20014864D0 (no) | 2001-10-05 |
NO20014864L NO20014864L (no) | 2001-12-05 |
Family
ID=22432894
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20014864A NO20014864L (no) | 1999-04-06 | 2001-10-05 | Substituerte 1,4-dihydro-indeno [1,2-C] pyrazoler som inhibitorer av tyrosin kinase |
Country Status (25)
Country | Link |
---|---|
EP (1) | EP1165544B1 (no) |
JP (1) | JP2002541150A (no) |
KR (1) | KR20020015034A (no) |
CN (1) | CN1368970A (no) |
AT (1) | ATE246684T1 (no) |
AU (1) | AU4037800A (no) |
BG (1) | BG106044A (no) |
BR (1) | BR0009561A (no) |
CA (1) | CA2368686A1 (no) |
CZ (1) | CZ20013580A3 (no) |
DE (1) | DE60004340T2 (no) |
DK (1) | DK1165544T3 (no) |
ES (1) | ES2207497T3 (no) |
HK (1) | HK1045500A1 (no) |
HU (1) | HUP0201514A3 (no) |
IL (1) | IL145564A0 (no) |
MX (1) | MXPA01010072A (no) |
NO (1) | NO20014864L (no) |
NZ (1) | NZ514269A (no) |
PL (1) | PL350891A1 (no) |
PT (1) | PT1165544E (no) |
SK (1) | SK14112001A3 (no) |
TR (1) | TR200103789T2 (no) |
WO (1) | WO2000059901A1 (no) |
ZA (1) | ZA200107838B (no) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6462036B1 (en) * | 1998-11-06 | 2002-10-08 | Basf Aktiengesellschaft | Tricyclic pyrazole derivatives |
US6297238B1 (en) * | 1999-04-06 | 2001-10-02 | Basf Aktiengesellschaft | Therapeutic agents |
US6956052B2 (en) | 2001-09-19 | 2005-10-18 | Pharmacia Corporation | Substituted pyrazolyl compounds for the treatment of inflammation |
EP1438293A2 (en) | 2001-09-19 | 2004-07-21 | Pharmacia Corporation | Substituted pyrazolyl benzenesulfamide compounds for the treatment of inflammation |
ATE353013T1 (de) * | 2002-02-19 | 2007-02-15 | Pfizer Italia Srl | Trizyklische pyrazolderivate, verfahren zu ihrer herstellung und ihre verwendung als antitumor mittel |
EA008770B1 (ru) * | 2002-05-15 | 2007-08-31 | Янссен Фамацевтика Н.В. | N-замещенные трициклические 3-аминопиразолы в качестве ингибиторов pdgf рецептора |
WO2004071507A1 (en) * | 2003-02-17 | 2004-08-26 | Pharmacia Italia S.P.A. | Tetracyclic pyrazole derivatives as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them |
ES2545666T3 (es) * | 2003-02-27 | 2015-09-14 | Abbvie Inc. | 5,10-Dihidro-11H-dibenzo[b,e][1,4]diazepin-11-ona como inhibidores de quinasa |
CA2517885A1 (en) * | 2003-03-07 | 2004-09-23 | Abbott Laboratories | Fused tri and tetra-cyclic pyrazole kinase inhibitors |
US7320986B2 (en) | 2003-03-07 | 2008-01-22 | Abbott Labortories | Fused tri and tetra-cyclic pyrazole kinase inhibitors |
US7468371B2 (en) | 2004-03-24 | 2008-12-23 | Abbott Laboratories Inc. | Tricyclic pyrazole kinase inhibitors |
CN102036963B (zh) * | 2008-05-23 | 2013-08-21 | 诺瓦提斯公司 | 作为蛋白酪氨酸激酶抑制剂的喹啉类和喹喔啉类衍生物 |
AT507953B1 (de) * | 2009-03-05 | 2011-02-15 | Apeptico Forschung & Entwicklung Gmbh | Verfahren zur vermeidung und zur behandlung einer hyperpermeabilität |
US8853207B2 (en) | 2012-04-12 | 2014-10-07 | Development Center For Biotechnology | Heterocyclic pyrazole compounds, method for preparing the same and use thereof |
CN104610149B (zh) * | 2015-02-10 | 2017-04-05 | 山东大学 | 一种茚并吡唑类小分子微管蛋白抑制剂及其制备方法与应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9226855D0 (en) * | 1992-12-23 | 1993-02-17 | Erba Carlo Spa | Vinylene-azaindole derivatives and process for their preparation |
EP1021182A1 (en) * | 1997-10-06 | 2000-07-26 | Basf Aktiengesellschaft | Indeno[1,2-c] pyrazole derivatives for inhibiting tyrosine kinase activity |
SK5282001A3 (en) * | 1998-11-06 | 2002-01-07 | Knoll Gmbh | Tricyclic pyrazole derivatives |
-
2000
- 2000-03-28 NZ NZ514269A patent/NZ514269A/en unknown
- 2000-03-28 TR TR2001/03789T patent/TR200103789T2/xx unknown
- 2000-03-28 PL PL00350891A patent/PL350891A1/xx not_active Application Discontinuation
- 2000-03-28 MX MXPA01010072A patent/MXPA01010072A/es unknown
- 2000-03-28 CZ CZ20013580A patent/CZ20013580A3/cs unknown
- 2000-03-28 KR KR1020017012696A patent/KR20020015034A/ko not_active Application Discontinuation
- 2000-03-28 IL IL14556400A patent/IL145564A0/xx unknown
- 2000-03-28 ES ES00919742T patent/ES2207497T3/es not_active Expired - Lifetime
- 2000-03-28 DK DK00919742T patent/DK1165544T3/da active
- 2000-03-28 HU HU0201514A patent/HUP0201514A3/hu unknown
- 2000-03-28 SK SK1411-2001A patent/SK14112001A3/sk unknown
- 2000-03-28 CN CN00808326A patent/CN1368970A/zh active Pending
- 2000-03-28 DE DE60004340T patent/DE60004340T2/de not_active Expired - Fee Related
- 2000-03-28 WO PCT/US2000/008192 patent/WO2000059901A1/en not_active Application Discontinuation
- 2000-03-28 BR BR0009561-3A patent/BR0009561A/pt not_active IP Right Cessation
- 2000-03-28 JP JP2000609412A patent/JP2002541150A/ja not_active Withdrawn
- 2000-03-28 AT AT00919742T patent/ATE246684T1/de not_active IP Right Cessation
- 2000-03-28 AU AU40378/00A patent/AU4037800A/en not_active Abandoned
- 2000-03-28 EP EP00919742A patent/EP1165544B1/en not_active Expired - Lifetime
- 2000-03-28 CA CA002368686A patent/CA2368686A1/en not_active Abandoned
- 2000-03-28 PT PT00919742T patent/PT1165544E/pt unknown
-
2001
- 2001-09-21 ZA ZA200107838A patent/ZA200107838B/en unknown
- 2001-10-05 NO NO20014864A patent/NO20014864L/no not_active Application Discontinuation
- 2001-10-24 BG BG106044A patent/BG106044A/xx unknown
-
2002
- 2002-06-28 HK HK02104887.6A patent/HK1045500A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
ATE246684T1 (de) | 2003-08-15 |
DE60004340T2 (de) | 2004-06-09 |
SK14112001A3 (sk) | 2002-04-04 |
EP1165544A1 (en) | 2002-01-02 |
EP1165544B1 (en) | 2003-08-06 |
ES2207497T3 (es) | 2004-06-01 |
PL350891A1 (en) | 2003-02-10 |
CZ20013580A3 (cs) | 2002-03-13 |
IL145564A0 (en) | 2002-06-30 |
JP2002541150A (ja) | 2002-12-03 |
BG106044A (en) | 2002-05-31 |
KR20020015034A (ko) | 2002-02-27 |
HK1045500A1 (zh) | 2002-11-29 |
CA2368686A1 (en) | 2000-10-12 |
CN1368970A (zh) | 2002-09-11 |
TR200103789T2 (tr) | 2002-04-22 |
NZ514269A (en) | 2003-10-31 |
MXPA01010072A (es) | 2004-03-26 |
DK1165544T3 (da) | 2003-12-01 |
BR0009561A (pt) | 2002-04-16 |
HUP0201514A2 (en) | 2002-08-28 |
WO2000059901A1 (en) | 2000-10-12 |
ZA200107838B (en) | 2003-03-24 |
DE60004340D1 (de) | 2003-09-11 |
AU4037800A (en) | 2000-10-23 |
NO20014864L (no) | 2001-12-05 |
HUP0201514A3 (en) | 2003-11-28 |
PT1165544E (pt) | 2003-12-31 |
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Legal Events
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |