NO20014617L - 1-Arensulfonyl-2-aryl-pyrrolidin- og -piperidin-derivater for behandling av CNS-sykdommer - Google Patents

1-Arensulfonyl-2-aryl-pyrrolidin- og -piperidin-derivater for behandling av CNS-sykdommer

Info

Publication number
NO20014617L
NO20014617L NO20014617A NO20014617A NO20014617L NO 20014617 L NO20014617 L NO 20014617L NO 20014617 A NO20014617 A NO 20014617A NO 20014617 A NO20014617 A NO 20014617A NO 20014617 L NO20014617 L NO 20014617L
Authority
NO
Norway
Prior art keywords
arensulfonyl
treatment
piperidine derivatives
cns diseases
aryl pyrrolidine
Prior art date
Application number
NO20014617A
Other languages
English (en)
Other versions
NO20014617D0 (no
NO319948B1 (no
Inventor
Vincent Mutel
Eric Vieira
Juergen Wichmann
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO20014617D0 publication Critical patent/NO20014617D0/no
Publication of NO20014617L publication Critical patent/NO20014617L/no
Publication of NO319948B1 publication Critical patent/NO319948B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34Tobacco-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36Opioid-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C07D207/48Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
NO20014617A 1999-03-25 2001-09-24 1-Arensulfonyl-2-aryl-pyrrolidin- og -piperidin-derivater for behandling av CNS-sykdommer NO319948B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99106004 1999-03-25
PCT/EP2000/002431 WO2000058285A1 (en) 1999-03-25 2000-03-18 1-arenesulfonyl-2-aryl-pyrrolidine and piperidine derivatives for the treatment of cns disorders

Publications (3)

Publication Number Publication Date
NO20014617D0 NO20014617D0 (no) 2001-09-24
NO20014617L true NO20014617L (no) 2001-09-24
NO319948B1 NO319948B1 (no) 2005-10-03

Family

ID=8237852

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20014617A NO319948B1 (no) 1999-03-25 2001-09-24 1-Arensulfonyl-2-aryl-pyrrolidin- og -piperidin-derivater for behandling av CNS-sykdommer

Country Status (34)

Country Link
US (1) US6284785B1 (no)
EP (1) EP1165510B1 (no)
JP (1) JP3590589B2 (no)
KR (1) KR100452648B1 (no)
CN (1) CN1150165C (no)
AR (1) AR028817A1 (no)
AT (1) ATE305451T1 (no)
AU (1) AU765212B2 (no)
BR (1) BR0009278A (no)
CA (1) CA2368418C (no)
CO (1) CO5050296A1 (no)
CZ (1) CZ20013402A3 (no)
DE (1) DE60022867T2 (no)
DK (1) DK1165510T3 (no)
ES (1) ES2249249T3 (no)
HK (1) HK1044944B (no)
HR (1) HRP20010682A2 (no)
HU (1) HUP0200284A3 (no)
IL (1) IL145301A0 (no)
JO (1) JO2274B1 (no)
MA (1) MA26779A1 (no)
MX (1) MXPA01009623A (no)
MY (1) MY125295A (no)
NO (1) NO319948B1 (no)
NZ (1) NZ514037A (no)
PE (1) PE20001583A1 (no)
PL (1) PL204436B1 (no)
RU (1) RU2248350C2 (no)
SI (1) SI1165510T1 (no)
TR (1) TR200102789T2 (no)
TW (1) TW575561B (no)
WO (1) WO2000058285A1 (no)
YU (1) YU67601A (no)
ZA (1) ZA200107689B (no)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6589978B2 (en) * 2000-06-30 2003-07-08 Hoffman-La Roche Inc. 1-sulfonyl pyrrolidine derivatives
US20040267010A1 (en) * 2001-02-02 2004-12-30 Forbes Ian Thomson Sulfonamide compounds, their preparation and use
TW200302717A (en) * 2002-02-06 2003-08-16 Schering Corp Novel gamma secretase inhibitors
US20060281803A1 (en) * 2003-09-23 2006-12-14 Lindsley Craig W Pyrazole modulators of metabotropic glutamate receptors
WO2005113542A2 (en) * 2004-05-20 2005-12-01 Elan Pharmaceuticals, Inc. N-cyclic sulfonamido inhibitors of gamma secretase
EP1803709B1 (en) 2004-09-30 2013-01-02 Takeda Pharmaceutical Company Limited Proton pump inhibitors
JP2009506069A (ja) 2005-08-26 2009-02-12 ブレインセルス,インコーポレイティド ムスカリン性受容体調節による神経発生
EP2258357A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis with acetylcholinesterase inhibitor
EP1919865B1 (en) 2005-08-30 2011-04-06 Takeda Pharmaceutical Company Limited 1-heterocyclylsulfonyl, 2-aminomethyl, 5- (hetero-) aryl substituted 1-h-pyrrole derivatives as acid secretion inhibitors
AU2006304787A1 (en) 2005-10-21 2007-04-26 Braincells, Inc. Modulation of neurogenesis by PDE inhibition
US20070112017A1 (en) 2005-10-31 2007-05-17 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
EP2021000A2 (en) 2006-05-09 2009-02-11 Braincells, Inc. Neurogenesis by modulating angiotensin
JP2009536667A (ja) 2006-05-09 2009-10-15 ブレインセルス,インコーポレイティド 5ht受容体介在性の神経新生
US7998971B2 (en) 2006-09-08 2011-08-16 Braincells Inc. Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
US8933105B2 (en) 2007-02-28 2015-01-13 Takeda Pharmaceutical Company Limited Pyrrole compounds
US8969387B2 (en) 2008-08-27 2015-03-03 Takeda Pharmaceutical Company Limited Pyrrole compounds
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
GB201702221D0 (en) 2017-02-10 2017-03-29 Univ Of Sussex Compounds
US10603313B2 (en) * 2017-07-31 2020-03-31 Chiromics, LLC Allosteric modulators of the mu opioid receptor
GB201803340D0 (en) 2018-03-01 2018-04-18 Univ Of Sussex Compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2685325B1 (fr) * 1991-12-20 1994-02-04 Adir Cie Nouveaux derives de pyrrolidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
GB9612884D0 (en) * 1996-06-20 1996-08-21 Smithkline Beecham Plc Novel compounds

Also Published As

Publication number Publication date
CN1345311A (zh) 2002-04-17
HK1044944A1 (en) 2002-11-08
HUP0200284A3 (en) 2003-04-28
BR0009278A (pt) 2001-12-26
ZA200107689B (en) 2002-12-18
PE20001583A1 (es) 2001-01-15
AU3291500A (en) 2000-10-16
EP1165510A1 (en) 2002-01-02
KR20010108403A (ko) 2001-12-07
AR028817A1 (es) 2003-05-28
HUP0200284A2 (en) 2002-06-29
CA2368418C (en) 2009-03-10
MXPA01009623A (es) 2002-05-06
IL145301A0 (en) 2002-06-30
CA2368418A1 (en) 2000-10-05
ATE305451T1 (de) 2005-10-15
PL350679A1 (en) 2003-01-27
PL204436B1 (pl) 2010-01-29
MA26779A1 (fr) 2004-12-20
DE60022867D1 (de) 2006-02-09
JP3590589B2 (ja) 2004-11-17
TR200102789T2 (tr) 2002-04-22
JO2274B1 (en) 2005-04-07
EP1165510B1 (en) 2005-09-28
CN1150165C (zh) 2004-05-19
MY125295A (en) 2006-07-31
DK1165510T3 (da) 2006-02-06
HK1044944B (zh) 2004-10-21
DE60022867T2 (de) 2006-06-22
TW575561B (en) 2004-02-11
US6284785B1 (en) 2001-09-04
HRP20010682A2 (en) 2002-10-31
CZ20013402A3 (cs) 2002-03-13
YU67601A (sh) 2004-09-03
JP2002540191A (ja) 2002-11-26
CO5050296A1 (es) 2001-06-27
AU765212B2 (en) 2003-09-11
NZ514037A (en) 2004-01-30
ES2249249T3 (es) 2006-04-01
SI1165510T1 (sl) 2005-12-31
NO20014617D0 (no) 2001-09-24
NO319948B1 (no) 2005-10-03
KR100452648B1 (ko) 2004-10-12
WO2000058285A1 (en) 2000-10-05
RU2248350C2 (ru) 2005-03-20

Similar Documents

Publication Publication Date Title
NO20014617L (no) 1-Arensulfonyl-2-aryl-pyrrolidin- og -piperidin-derivater for behandling av CNS-sykdommer
DE60105144D1 (de) Pyrrolidin und piperidin derivate für die behandlung von neurodegenerativen erkrankungen
NO20013380L (no) 2-aminobenzoksazinonderivater for behandling av fedme
EE200200442A (et) Piperasiini ja piperidiini derivaadid neuronaalsete kahjustuste raviks
NO20031442D0 (no) Morfolin-acetamidderivater for behandling av inflammatoriske sykdommer
NO20013381D0 (no) 2-oksybenzoksazinonderivater for behandling av fedme
NO20015542L (no) Fremgangsmåte for fremstilling og anvendelse av N- desmetylzopikloner
NO20024775D0 (no) Hydroksyfenyl-piperidin-4-yliden-metyl-benzamidderivater til behandling av smerte
NO20014314D0 (no) Blandinger og metoder for behandling av stafylokokkisk infeksjon
HUP9900927A3 (en) Substituted 4-(1h-benzimidazol-2-yl-amino)piperidines useful for the treatment of allergic diseases
NO20023448L (no) Medikamentkombinasjon for behandling av depresjon og beslektede forstyrrelser omfattende mirtazapin
NO20020784L (no) Medikament for behandling av brudd
EE04235B1 (et) Toimeainete, nimelt tetrahüdropüridiinide ja atsetüülkoliinesteraasi inhibiitorite, kombinatsioon Alzheimeri tõve tüüpi seniildementsuse raviks
NO20026005L (no) Indolderivater nyttige for behandlingen av CNS-forstyrrelser
NO20012612L (no) Isonipecotamider for behandlingen av integrin-formidlede sykdommer
NO20030127D0 (no) Indolderivater nyttige for behandling av CNS-forstyrrelser
NO20026148D0 (no) Medisiner for forhindring og behandling av neurodegenerative sykdommer
NO20026029D0 (no) Indolderivater nyttige for behandlingen av CNS-forstyrrelser
NO20033290D0 (no) Pyrrolderivater for behandling av cytokinformidlede sykdommer
NO20014026L (no) Krampestillende derivater til behandling av betydelig skjelving
NO20026028D0 (no) Indolderivater nyttige for behandlingen av CNS-forstyrrelser
NO20014476D0 (no) Behandling av hiatial hernia
NO20014092D0 (no) Behandling av infertilitet
NO20014093D0 (no) Behandling av infertilitet
SE9902239D0 (sv) Kornisch bestående av flera delar