NO20014589L - Pyridin- og pyrimidinderivater og anvendelse derav som inhibitorer av cytokin-mediert sykdom - Google Patents

Pyridin- og pyrimidinderivater og anvendelse derav som inhibitorer av cytokin-mediert sykdom

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Publication number
NO20014589L
NO20014589L NO20014589A NO20014589A NO20014589L NO 20014589 L NO20014589 L NO 20014589L NO 20014589 A NO20014589 A NO 20014589A NO 20014589 A NO20014589 A NO 20014589A NO 20014589 L NO20014589 L NO 20014589L
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NO
Norway
Prior art keywords
halo
hydroxy
amino
hydrogen
group
Prior art date
Application number
NO20014589A
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English (en)
Norwegian (no)
Other versions
NO20014589D0 (no
Inventor
John Graham Cumming
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20014589D0 publication Critical patent/NO20014589D0/no
Publication of NO20014589L publication Critical patent/NO20014589L/no

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61P11/06—Antiasthmatics
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    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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    • A61P37/00—Drugs for immunological or allergic disorders
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

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  • Health & Medical Sciences (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Vascular Medicine (AREA)
  • AIDS & HIV (AREA)
  • Gastroenterology & Hepatology (AREA)
NO20014589A 1999-03-23 2001-09-21 Pyridin- og pyrimidinderivater og anvendelse derav som inhibitorer av cytokin-mediert sykdom NO20014589L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9906566.6A GB9906566D0 (en) 1999-03-23 1999-03-23 Chemical compounds
PCT/GB2000/001006 WO2000056738A1 (en) 1999-03-23 2000-03-17 Pyridine and pyrimidine derivatives and their use as inhibitors of cytokine mediated disease

Publications (2)

Publication Number Publication Date
NO20014589D0 NO20014589D0 (no) 2001-09-21
NO20014589L true NO20014589L (no) 2001-11-21

Family

ID=10850125

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20014589A NO20014589L (no) 1999-03-23 2001-09-21 Pyridin- og pyrimidinderivater og anvendelse derav som inhibitorer av cytokin-mediert sykdom

Country Status (20)

Country Link
US (1) US6784174B1 (zh)
EP (1) EP1165566B1 (zh)
JP (1) JP2002540112A (zh)
KR (1) KR20010103798A (zh)
CN (3) CN1222527C (zh)
AT (1) ATE247661T1 (zh)
AU (1) AU757028B2 (zh)
BR (1) BR0009223A (zh)
CA (1) CA2367866A1 (zh)
DE (1) DE60004655T2 (zh)
DK (1) DK1165566T3 (zh)
ES (1) ES2204539T3 (zh)
GB (1) GB9906566D0 (zh)
HK (2) HK1041886A1 (zh)
IL (1) IL145303A0 (zh)
NO (1) NO20014589L (zh)
NZ (1) NZ514042A (zh)
PT (1) PT1165566E (zh)
WO (1) WO2000056738A1 (zh)
ZA (1) ZA200107501B (zh)

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NO20014589D0 (no) 2001-09-21
CN1660849A (zh) 2005-08-31
AU3440100A (en) 2000-10-09
BR0009223A (pt) 2001-12-26
ES2204539T3 (es) 2004-05-01
US6784174B1 (en) 2004-08-31
CN1308329C (zh) 2007-04-04
EP1165566B1 (en) 2003-08-20
HK1041886A1 (zh) 2002-07-26
CN1351604A (zh) 2002-05-29
NZ514042A (en) 2003-10-31
CN1222527C (zh) 2005-10-12
CN1911931A (zh) 2007-02-14
DE60004655T2 (de) 2004-04-15
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IL145303A0 (en) 2002-06-30
WO2000056738A1 (en) 2000-09-28
DK1165566T3 (da) 2003-11-24
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