NO20012838L - Tiourea-inhibitorer for herpesvirus - Google Patents

Tiourea-inhibitorer for herpesvirus

Info

Publication number
NO20012838L
NO20012838L NO20012838A NO20012838A NO20012838L NO 20012838 L NO20012838 L NO 20012838L NO 20012838 A NO20012838 A NO 20012838A NO 20012838 A NO20012838 A NO 20012838A NO 20012838 L NO20012838 L NO 20012838L
Authority
NO
Norway
Prior art keywords
herpes virus
thiourea inhibitors
thiourea
inhibitors
herpes
Prior art date
Application number
NO20012838A
Other languages
English (en)
Norwegian (no)
Other versions
NO20012838D0 (no
Inventor
Jonathan David Bloom
Kevin Joseph Curran
Martin Joseph Digrandi
Russel George Dushin
Stanley Albert Lang
Emily Boucher Norton
Adma Antonia Ross
Bryan Mark O'hara
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of NO20012838D0 publication Critical patent/NO20012838D0/no
Publication of NO20012838L publication Critical patent/NO20012838L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/84Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D307/85Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04Derivatives of thiourea
    • C07C335/16Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C335/20Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04Derivatives of thiourea
    • C07C335/16Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C335/22Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/81Radicals substituted by nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
NO20012838A 1998-12-09 2001-06-08 Tiourea-inhibitorer for herpesvirus NO20012838L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20856198A 1998-12-09 1998-12-09
PCT/US1999/028837 WO2000034238A1 (en) 1998-12-09 1999-12-06 Thiourea inhibitors of herpes viruses

Publications (2)

Publication Number Publication Date
NO20012838D0 NO20012838D0 (no) 2001-06-08
NO20012838L true NO20012838L (no) 2001-08-08

Family

ID=22775050

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20012838A NO20012838L (no) 1998-12-09 2001-06-08 Tiourea-inhibitorer for herpesvirus

Country Status (26)

Country Link
EP (1) EP1137632B1 (xx)
JP (1) JP2002531545A (xx)
KR (1) KR20010089559A (xx)
CN (1) CN1332725A (xx)
AR (1) AR033789A1 (xx)
AT (1) ATE272052T1 (xx)
AU (1) AU1934500A (xx)
BG (1) BG105583A (xx)
BR (1) BR9916086A (xx)
CA (1) CA2351403A1 (xx)
CZ (1) CZ20011957A3 (xx)
DE (1) DE69919023T2 (xx)
DK (1) DK1137632T3 (xx)
EA (1) EA200100634A1 (xx)
ES (1) ES2224733T3 (xx)
HU (1) HUP0104763A3 (xx)
ID (1) ID30287A (xx)
IL (1) IL143262A0 (xx)
NO (1) NO20012838L (xx)
NZ (1) NZ512108A (xx)
PL (1) PL348178A1 (xx)
PT (1) PT1137632E (xx)
SK (1) SK7702001A3 (xx)
TR (1) TR200101597T2 (xx)
WO (1) WO2000034238A1 (xx)
ZA (1) ZA200104144B (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6844367B1 (en) 1999-09-17 2005-01-18 Millennium Pharmaceuticals, Inc. Benzamides and related inhibitors of factor Xa
EP1259485B1 (en) 2000-02-29 2005-11-30 Millennium Pharmaceuticals, Inc. BENZAMIDES AND RELATED INHIBITORS OF FACTOR Xa
DE10217518A1 (de) * 2002-04-19 2003-11-06 Bayer Ag Lactone
DE10222024A1 (de) * 2002-05-17 2003-11-27 Bayer Ag Lactame
DE10257786A1 (de) * 2002-12-11 2004-07-01 Bayer Healthcare Ag Oxazolidinone
ES2382055T3 (es) 2006-11-02 2012-06-04 Millennium Pharmaceuticals, Inc. Métodos para sintetizar sales farmacéuticas de un inhibidor del factor Xa
US9309212B2 (en) 2011-05-24 2016-04-12 The Wistar Institute Compositions and methods for modulating the activity of Epstein-Barr nuclear antigen 1
JP6372666B2 (ja) * 2012-11-03 2018-08-15 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング サイトメガロウイルスの阻害剤
EP2914591B1 (en) * 2012-11-03 2017-10-11 Boehringer Ingelheim International GmbH Inhibitors of cytomegalovirus
WO2022150962A1 (en) * 2021-01-12 2022-07-21 Westlake Pharmaceutical (Hangzhou) Co., Ltd. Protease inhibitors, preparation, and uses thereof
CN118076593A (zh) * 2021-09-07 2024-05-24 上海齐鲁制药研究中心有限公司 3CLpro蛋白酶抑制剂

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU210683B (en) * 1990-06-18 1995-06-28 Sandoz Ag Process for producing n-benzyl-n1-(phenyl-alkyl)-thiourea derivatives and pharmaceutical compositions containing the same
JPH11503110A (ja) * 1995-02-17 1999-03-23 スミスクライン・ビーチャム・コーポレイション Il−8受容体拮抗剤
GB9519270D0 (en) * 1995-09-21 1995-11-22 Sandoz Pharma Uk Organic compounds
NZ332405A (en) * 1996-04-23 2000-06-23 Vertex Pharma oxazolyl, thiazolyl or phenyl urea derivatives as inhibitors of inosine monophosphate dehydrogenase enzyme

Also Published As

Publication number Publication date
ID30287A (id) 2001-11-15
AR033789A1 (es) 2004-01-07
ATE272052T1 (de) 2004-08-15
WO2000034238A1 (en) 2000-06-15
CN1332725A (zh) 2002-01-23
ZA200104144B (en) 2002-08-21
EP1137632A1 (en) 2001-10-04
JP2002531545A (ja) 2002-09-24
HUP0104763A2 (hu) 2002-04-29
ES2224733T3 (es) 2005-03-01
TR200101597T2 (tr) 2001-10-22
IL143262A0 (en) 2002-04-21
BG105583A (en) 2001-12-29
DK1137632T3 (da) 2004-11-01
PT1137632E (pt) 2004-11-30
KR20010089559A (ko) 2001-10-06
NO20012838D0 (no) 2001-06-08
SK7702001A3 (en) 2002-04-04
BR9916086A (pt) 2001-09-04
EP1137632B1 (en) 2004-07-28
NZ512108A (en) 2003-09-26
CA2351403A1 (en) 2000-06-15
CZ20011957A3 (cs) 2001-10-17
PL348178A1 (en) 2002-05-06
DE69919023T2 (de) 2005-07-28
EA200100634A1 (ru) 2001-10-22
HUP0104763A3 (en) 2005-04-28
DE69919023D1 (de) 2004-09-02
AU1934500A (en) 2000-06-26

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application