NO20012544L - Substituerte benzo[de]isokinolin-1,3-dioner - Google Patents

Substituerte benzo[de]isokinolin-1,3-dioner

Info

Publication number
NO20012544L
NO20012544L NO20012544A NO20012544A NO20012544L NO 20012544 L NO20012544 L NO 20012544L NO 20012544 A NO20012544 A NO 20012544A NO 20012544 A NO20012544 A NO 20012544A NO 20012544 L NO20012544 L NO 20012544L
Authority
NO
Norway
Prior art keywords
isoquinoline
dione
substituted benzo
benzo
substituted
Prior art date
Application number
NO20012544A
Other languages
English (en)
Norwegian (no)
Other versions
NO20012544D0 (no
Inventor
Werner Mederski
Ralf Devant
Gerhard Barnickel
Sabine Bernotat-Danielowski
Guido Melzer
Peter Raddatz
Zhengdong Wu
Daljit Dhanoa
Richard M Soll
James Rinker
Todd L Graybill
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of NO20012544D0 publication Critical patent/NO20012544D0/no
Publication of NO20012544L publication Critical patent/NO20012544L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04Ortho- or peri-condensed ring systems
    • C07D221/06Ring systems of three rings
    • C07D221/14Aza-phenalenes, e.g. 1,8-naphthalimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20012544A 1998-11-25 2001-05-23 Substituerte benzo[de]isokinolin-1,3-dioner NO20012544L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19941398A 1998-11-25 1998-11-25
US39878399A 1999-09-20 1999-09-20
PCT/EP1999/008561 WO2000032577A2 (en) 1998-11-25 1999-11-09 Substituted benzo[de]isoquinoline-1,3-diones

Publications (2)

Publication Number Publication Date
NO20012544D0 NO20012544D0 (no) 2001-05-23
NO20012544L true NO20012544L (no) 2001-05-23

Family

ID=26894745

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20012544A NO20012544L (no) 1998-11-25 2001-05-23 Substituerte benzo[de]isokinolin-1,3-dioner

Country Status (15)

Country Link
EP (1) EP1144381A2 (xx)
JP (1) JP2002537225A (xx)
KR (1) KR20010080569A (xx)
CN (1) CN1330638A (xx)
AU (1) AU760136B2 (xx)
BR (1) BR9915648A (xx)
CA (1) CA2352045A1 (xx)
CZ (1) CZ20011782A3 (xx)
HU (1) HUP0104520A3 (xx)
ID (1) ID28982A (xx)
NO (1) NO20012544L (xx)
PL (1) PL348204A1 (xx)
SK (1) SK7022001A3 (xx)
TW (1) TW473474B (xx)
WO (1) WO2000032577A2 (xx)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998007421A1 (fr) * 1996-08-16 1998-02-26 Ishihara Sangyo Kaisha, Ltd. Composition medicinale
EP1088821A1 (en) * 1999-09-28 2001-04-04 Applied Research Systems ARS Holding N.V. Pharmaceutically active sulfonamide derivatives
US7547716B2 (en) 2001-06-08 2009-06-16 Institute Of Medicinal Molecular Design, Inc. Sulfonamide derivatives
US6693198B2 (en) * 2002-04-22 2004-02-17 Xanthus Life Sciences, Inc. Amonafide salts
US8097725B2 (en) * 2004-12-03 2012-01-17 Roche Diagnostics Operations, Inc. Luminescent indicator dye and optical sensor
FR2915685A1 (fr) * 2007-05-02 2008-11-07 Thales Sa Compose fluorescent a l'etat solide dans l'eau,procede de synthese et utilisation dans des capteurs
EP2970227B1 (en) * 2013-03-15 2018-01-10 Alumend, LLC Compositions and methods of using the compositions for plaque softening
CN105492428A (zh) * 2013-05-01 2016-04-13 中央研究院 治疗β-地中海贫血和镰状细胞病的方法和组合物
CN103450176B (zh) * 2013-08-15 2016-07-06 大连理工大学 一类含2-(4-氨基苯基)苯并噻唑萘酰亚胺化合物及其应用
EP3194368B1 (en) * 2014-09-19 2020-12-23 MacKay Medical Foundation the Presbyterian Church in Taiwan MacKay Memorial Hospital Benzo-heterocyclic compounds and their applications
CN106905237B (zh) * 2017-02-08 2019-05-14 上海师范大学 一种pH和乏氧双响应定位肿瘤细胞的萘酰亚胺类比率荧光探针及其合成方法
CN110283123B (zh) * 2019-07-08 2022-06-17 桂林医学院 4-对甲苯磺酰基哌嗪-3-硝基-1,8-萘酰亚胺衍生物及其合成方法和应用
CN110272388B (zh) * 2019-07-08 2022-06-17 桂林医学院 4-二硫代甲酸哌嗪-3-硝基-1,8-萘酰亚胺衍生物及其合成方法和应用
CN110407865B (zh) * 2019-08-02 2022-04-15 山东师范大学 基于苯磺酰胺结构的式(i)化合物及其制备方法与应用
CN111518075B (zh) * 2020-04-17 2023-03-28 西南大学 萘酰亚胺哌嗪三唑类化合物及其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2423546C2 (de) * 1974-05-15 1983-01-27 Hoechst Ag, 6000 Frankfurt Verfahren zur Herstellung von 4-Amino-1,8- naphthalsäure-N-arylimid-Verbindungen
ES459497A1 (es) * 1977-06-04 1978-04-16 Made Labor Sa Un metodo para la preparacion industrial de naftalimidas y sus derivados.
DE3635711A1 (de) * 1986-10-21 1988-04-28 Knoll Ag 5-nitrobenzo(de)isochinolin-1,3-dione, ihre herstellung und verwendung
DK0930883T3 (da) * 1996-10-21 2006-05-22 Nps Allelix Corp Neurotrofinantagonister til behandling af epilepsi, Alzheimers sygdom og smerte
WO1998018764A1 (de) * 1996-10-28 1998-05-07 Merck Patent Gmbh Dihydrobenzoanthracenone, -pyrimidinone oder dihydronaphthochinolinone

Also Published As

Publication number Publication date
WO2000032577A2 (en) 2000-06-08
TW473474B (en) 2002-01-21
JP2002537225A (ja) 2002-11-05
EP1144381A2 (en) 2001-10-17
BR9915648A (pt) 2001-08-14
CN1330638A (zh) 2002-01-09
KR20010080569A (ko) 2001-08-22
NO20012544D0 (no) 2001-05-23
CZ20011782A3 (cs) 2001-09-12
SK7022001A3 (en) 2002-09-10
CA2352045A1 (en) 2000-06-08
HUP0104520A3 (en) 2002-10-28
AU2660300A (en) 2000-06-19
PL348204A1 (en) 2002-05-06
AU760136B2 (en) 2003-05-08
HUP0104520A2 (hu) 2002-04-29
WO2000032577A3 (en) 2000-09-21
ID28982A (id) 2001-07-19

Similar Documents

Publication Publication Date Title
NO20012544L (no) Substituerte benzo[de]isokinolin-1,3-dioner
DE60038481D1 (de) Kristalline form des (r)-2-äää3-methyl-4-(2,2,2-trifluorethoxy)-2-pyridinylümethylüsulfinylü-1h-benzimidazols
NO992821L (no) Ketobenzamider som calpain-inhibitorer
PT923554E (pt) N-benzilpiperidina e derivados tetrahidropiridina
NO974236L (no) Disubstituerte 1,4-piperidinestere og amider som har 5-HT4antagonistisk aktivitet
ES2072096T3 (es) 4-fenilpiperidinas n-sustituidas antagonistas de opioides.
DE69903333D1 (de) Crf rezeptor-antagonisten und darauf bezogene methoden
AU9281198A (en) Benzofuran derivatives
TR200403436T2 (tr) Kristalin 1-metilkarbapenem türevleri.
NO304833B1 (no) Nye pyrrolokarbazoler
NO20012543L (no) Substituerte benzo[de]isokinolin-1,3-dioner
ATE273970T1 (de) N-acyl und n-aroyl aralkylamide
NO20021503L (no) Kinazolinoner
DE60034577D1 (de) In 4-stellung substituierte piperidinderivate
PT1204659E (pt) Benzofuranos serotoninergicos
EP1786815A4 (en) SPIRO COMPOUNDS AND METHOD FOR MODULATING CHEMOKIN RECEPTOR ACTIVITY
NO20021502L (no) Kinazolinoner
NO20010626L (no) N-substituerte azabicykloheptanderivater, deres fremstilling og anvendelse
NO971424L (no) Nye heterocyklisk substituerte imidazolo-kinoksalinoner, deres fremstilling og anvendelse
NO20020886L (no) Nye integrin- <alfa>v<beta>3-inhibitorer
ATE206125T1 (de) Furoindolizine
NZ335631A (en) Antipsychotic (neuroleptic) piperidine derivatives
NO20004075L (no) Substituerte pyrimidin-2-yloksy-karboksylsyrederivater, fremstilling av disse og deres anvendelse som endotelin- antagonister
ATE260918T1 (de) Crf rezeptor-antagonisten und darauf bezogene methoden
NO20002154L (no) Nye heterocykliske substituerte alfa-hydroksykarboksylsyre- derivater

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application