NO20012544L - Substituted benzo [de] isoquinoline-1,3-dione - Google Patents
Substituted benzo [de] isoquinoline-1,3-dioneInfo
- Publication number
- NO20012544L NO20012544L NO20012544A NO20012544A NO20012544L NO 20012544 L NO20012544 L NO 20012544L NO 20012544 A NO20012544 A NO 20012544A NO 20012544 A NO20012544 A NO 20012544A NO 20012544 L NO20012544 L NO 20012544L
- Authority
- NO
- Norway
- Prior art keywords
- isoquinoline
- dione
- substituted benzo
- benzo
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/14—Aza-phenalenes, e.g. 1,8-naphthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Nye forbindelser med formel I hvor R, R1 og R2 har de angitte betydninger, og deres salter solvater, som glykoprotein lb antagonister.Novel compounds of formula I wherein R, R 1 and R 2 have the indicated meanings and their salts solvates, as glycoprotein 1b antagonists.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US19941398A | 1998-11-25 | 1998-11-25 | |
US39878399A | 1999-09-20 | 1999-09-20 | |
PCT/EP1999/008561 WO2000032577A2 (en) | 1998-11-25 | 1999-11-09 | Substituted benzo[de]isoquinoline-1,3-diones |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20012544D0 NO20012544D0 (en) | 2001-05-23 |
NO20012544L true NO20012544L (en) | 2001-05-23 |
Family
ID=26894745
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20012544A NO20012544L (en) | 1998-11-25 | 2001-05-23 | Substituted benzo [de] isoquinoline-1,3-dione |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP1144381A2 (en) |
JP (1) | JP2002537225A (en) |
KR (1) | KR20010080569A (en) |
CN (1) | CN1330638A (en) |
AU (1) | AU760136B2 (en) |
BR (1) | BR9915648A (en) |
CA (1) | CA2352045A1 (en) |
CZ (1) | CZ20011782A3 (en) |
HU (1) | HUP0104520A3 (en) |
ID (1) | ID28982A (en) |
NO (1) | NO20012544L (en) |
PL (1) | PL348204A1 (en) |
SK (1) | SK7022001A3 (en) |
TW (1) | TW473474B (en) |
WO (1) | WO2000032577A2 (en) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998007421A1 (en) * | 1996-08-16 | 1998-02-26 | Ishihara Sangyo Kaisha, Ltd. | Medicinal composition |
EP1088821A1 (en) * | 1999-09-28 | 2001-04-04 | Applied Research Systems ARS Holding N.V. | Pharmaceutically active sulfonamide derivatives |
EP1402890B1 (en) * | 2001-06-08 | 2008-01-09 | Institute of Medicinal Molecular Design, Inc. | Sulfonamide derivatives |
US6693198B2 (en) * | 2002-04-22 | 2004-02-17 | Xanthus Life Sciences, Inc. | Amonafide salts |
US8097725B2 (en) | 2004-12-03 | 2012-01-17 | Roche Diagnostics Operations, Inc. | Luminescent indicator dye and optical sensor |
FR2915685A1 (en) * | 2007-05-02 | 2008-11-07 | Thales Sa | New fluorescent compounds of solid state in water, with naphthalimide base, useful for allowing the grafting on transducer, which is a biological substance, in biosensor and security or explosive detectors, and as markers |
WO2014149198A1 (en) * | 2013-03-15 | 2014-09-25 | Alumend, Llc | Compositions and methods of using the compositions for plaque softening |
CN107417616A (en) | 2013-05-01 | 2017-12-01 | 中央研究院 | Treat the method and composition of beta Thalassemia and drepanocytosis |
CN103450176B (en) * | 2013-08-15 | 2016-07-06 | 大连理工大学 | One class is containing 2-(4-aminophenyl) benzothiazole naphthalimide compound and application thereof |
WO2016041511A1 (en) | 2014-09-19 | 2016-03-24 | Yen-Ta Lu | Benzo-heterocyclic compounds and their applications |
CN106905237B (en) * | 2017-02-08 | 2019-05-14 | 上海师范大学 | A kind of pH and weary oxygen double-bang firecracker answer the naphthalimide ratio fluorescent probe and its synthetic method of positioning tumor cell |
CN110283123B (en) * | 2019-07-08 | 2022-06-17 | 桂林医学院 | 4-p-toluenesulfonyl piperazine-3-nitro-1, 8-naphthalimide derivative and synthesis method and application thereof |
CN110272388B (en) * | 2019-07-08 | 2022-06-17 | 桂林医学院 | 4-dithioformic acid piperazine-3-nitro-1, 8-naphthalimide derivative and synthesis method and application thereof |
CN110407865B (en) * | 2019-08-02 | 2022-04-15 | 山东师范大学 | Benzene sulfonamide structure-based compound shown as formula (I) and preparation method and application thereof |
CN111518075B (en) * | 2020-04-17 | 2023-03-28 | 西南大学 | Naphthalimide piperazine triazole compound and preparation method and application thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2423546C2 (en) * | 1974-05-15 | 1983-01-27 | Hoechst Ag, 6000 Frankfurt | Process for the preparation of 4-amino-1,8-naphthalic acid-N-arylimide compounds |
ES459497A1 (en) * | 1977-06-04 | 1978-04-16 | Made Labor Sa | N(Aminoalkyl)-naphthalimides and their derivatives |
DE3635711A1 (en) * | 1986-10-21 | 1988-04-28 | Knoll Ag | 5-NITROBENZO (DE) ISOCHINOLIN-1,3-DIONE, THEIR PRODUCTION AND USE |
BR9712424A (en) * | 1996-10-21 | 2001-11-20 | Allelix Biopharma | Deneurotrophin antagonist pharmaceutical composition |
AU4946697A (en) * | 1996-10-28 | 1998-05-22 | Merck Patent Gmbh | Dihydrobenzoanthracenone, -pyrimidinone or dihydronaphtoquinolinone |
-
1999
- 1999-11-09 JP JP2000585219A patent/JP2002537225A/en active Pending
- 1999-11-09 CZ CZ20011782A patent/CZ20011782A3/en unknown
- 1999-11-09 EP EP99968783A patent/EP1144381A2/en not_active Withdrawn
- 1999-11-09 KR KR1020017006547A patent/KR20010080569A/en not_active Application Discontinuation
- 1999-11-09 PL PL99348204A patent/PL348204A1/en unknown
- 1999-11-09 BR BR9915648-2A patent/BR9915648A/en not_active IP Right Cessation
- 1999-11-09 ID IDW00200101392A patent/ID28982A/en unknown
- 1999-11-09 WO PCT/EP1999/008561 patent/WO2000032577A2/en not_active Application Discontinuation
- 1999-11-09 HU HU0104520A patent/HUP0104520A3/en unknown
- 1999-11-09 SK SK702-2001A patent/SK7022001A3/en unknown
- 1999-11-09 CN CN99813687A patent/CN1330638A/en active Pending
- 1999-11-09 CA CA002352045A patent/CA2352045A1/en not_active Abandoned
- 1999-11-09 AU AU26603/00A patent/AU760136B2/en not_active Ceased
- 1999-11-24 TW TW088120540A patent/TW473474B/en not_active IP Right Cessation
-
2001
- 2001-05-23 NO NO20012544A patent/NO20012544L/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
HUP0104520A2 (en) | 2002-04-29 |
ID28982A (en) | 2001-07-19 |
WO2000032577A3 (en) | 2000-09-21 |
KR20010080569A (en) | 2001-08-22 |
NO20012544D0 (en) | 2001-05-23 |
CN1330638A (en) | 2002-01-09 |
PL348204A1 (en) | 2002-05-06 |
WO2000032577A2 (en) | 2000-06-08 |
JP2002537225A (en) | 2002-11-05 |
CZ20011782A3 (en) | 2001-09-12 |
CA2352045A1 (en) | 2000-06-08 |
BR9915648A (en) | 2001-08-14 |
SK7022001A3 (en) | 2002-09-10 |
TW473474B (en) | 2002-01-21 |
EP1144381A2 (en) | 2001-10-17 |
AU2660300A (en) | 2000-06-19 |
AU760136B2 (en) | 2003-05-08 |
HUP0104520A3 (en) | 2002-10-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20012544L (en) | Substituted benzo [de] isoquinoline-1,3-dione | |
NO992821L (en) | Ketobenzamides as Calpain Inhibitors | |
PT923554E (en) | N-BENZYLPIPERIDINE AND TETRAHYDROPYRIDINE DERIVATIVES | |
NO974236L (en) | Disubstituted 1,4-piperidine esters and amides having 5-HT 4 antagonistic activity | |
ES2072096T3 (en) | 4-PHENYLPIPERIDINES N-SUBSTITUTED OPIOID ANTAGONISTS. | |
NO20006282L (en) | New cyclosporins | |
DE69903333T2 (en) | CRF RECEPTOR ANTAGONISTS AND RELATED METHODS | |
AU9281198A (en) | Benzofuran derivatives | |
TR200403436T2 (en) | Crystalline 1-methylcarbapenem derivatives. | |
NO953052L (en) | New pyrrolocarbazoles | |
NO20012543L (en) | Substituted benzo [de] isoquinoline-1,3-dione | |
DE69919436D1 (en) | N-acyl and N-aroyl aralkylamides | |
NO20021503L (en) | quinazolinones | |
DE60034577D1 (en) | IN 4-POSITION SUBSTITUTED PIPERIDINE DERIVATIVES | |
DE60006825D1 (en) | SEROTONERGE BENZOFURANE | |
FI905957A (en) | FOERFARANDE FOER FRAMSTAELLNING AV SUBSTITUERADE CYKLOHEXENER, SOM VERKAR PAO DET CENTRALA NERVSYSTEMET. | |
ATE521610T1 (en) | SPIR COMPOUNDS AND METHODS FOR MODULATING CHEMOKINE RECEPTOR ACTIVITY | |
NO20021502L (en) | quinazolinones | |
NO20010626L (en) | N-substituted azabicycloheptane derivatives, their preparation and use | |
NO971424L (en) | Novel heterocyclic substituted imidazoloquinoxalinones, their preparation and use | |
NO20020886L (en) | Novel integrin <alfa> v <beta> 3 inhibitors | |
DE69706950D1 (en) | Furoindolizine | |
NZ335631A (en) | Antipsychotic (neuroleptic) piperidine derivatives | |
NO20004075L (en) | Substituted pyrimidin-2-yloxy-carboxylic acid derivatives, their preparation and their use as endothelin antagonists | |
NO20002154L (en) | Novel heterocyclic substituted alpha hydroxycarboxylic acid derivatives |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |