TW473474B - Substituted benzo[de]isoquinoline-1,3-diones - Google Patents
Substituted benzo[de]isoquinoline-1,3-diones Download PDFInfo
- Publication number
- TW473474B TW473474B TW088120540A TW88120540A TW473474B TW 473474 B TW473474 B TW 473474B TW 088120540 A TW088120540 A TW 088120540A TW 88120540 A TW88120540 A TW 88120540A TW 473474 B TW473474 B TW 473474B
- Authority
- TW
- Taiwan
- Prior art keywords
- benzo
- cns
- page
- ministry
- national standard
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/14—Aza-phenalenes, e.g. 1,8-naphthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US19941398A | 1998-11-25 | 1998-11-25 | |
US39878399A | 1999-09-20 | 1999-09-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
TW473474B true TW473474B (en) | 2002-01-21 |
Family
ID=26894745
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW088120540A TW473474B (en) | 1998-11-25 | 1999-11-24 | Substituted benzo[de]isoquinoline-1,3-diones |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP1144381A2 (xx) |
JP (1) | JP2002537225A (xx) |
KR (1) | KR20010080569A (xx) |
CN (1) | CN1330638A (xx) |
AU (1) | AU760136B2 (xx) |
BR (1) | BR9915648A (xx) |
CA (1) | CA2352045A1 (xx) |
CZ (1) | CZ20011782A3 (xx) |
HU (1) | HUP0104520A3 (xx) |
ID (1) | ID28982A (xx) |
NO (1) | NO20012544D0 (xx) |
PL (1) | PL348204A1 (xx) |
SK (1) | SK7022001A3 (xx) |
TW (1) | TW473474B (xx) |
WO (1) | WO2000032577A2 (xx) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998007421A1 (fr) * | 1996-08-16 | 1998-02-26 | Ishihara Sangyo Kaisha, Ltd. | Composition medicinale |
EP1088821A1 (en) * | 1999-09-28 | 2001-04-04 | Applied Research Systems ARS Holding N.V. | Pharmaceutically active sulfonamide derivatives |
WO2003007931A1 (fr) * | 2001-06-08 | 2003-01-30 | Institute Of Medicinal Molecular Design. Inc. | Derives de sulfonamide |
US6693198B2 (en) * | 2002-04-22 | 2004-02-17 | Xanthus Life Sciences, Inc. | Amonafide salts |
US8097725B2 (en) | 2004-12-03 | 2012-01-17 | Roche Diagnostics Operations, Inc. | Luminescent indicator dye and optical sensor |
FR2915685A1 (fr) * | 2007-05-02 | 2008-11-07 | Thales Sa | Compose fluorescent a l'etat solide dans l'eau,procede de synthese et utilisation dans des capteurs |
EP3348555B1 (en) * | 2013-03-15 | 2020-11-25 | Alumend, LLC | Compositions and methods of using the compositions for plaque softening |
CN107417616A (zh) | 2013-05-01 | 2017-12-01 | 中央研究院 | 治疗β‑地中海贫血和镰状细胞病的方法和组合物 |
CN103450176B (zh) * | 2013-08-15 | 2016-07-06 | 大连理工大学 | 一类含2-(4-氨基苯基)苯并噻唑萘酰亚胺化合物及其应用 |
KR20170090408A (ko) | 2014-09-19 | 2017-08-07 | 매카이 메디컬 파운데이션 더 프레즈비티리언 처치 인 타이완 매카이 메모리얼 호스피탈 | 벤조-헤테로시클릭 화합물 및 이의 적용 |
CN106905237B (zh) * | 2017-02-08 | 2019-05-14 | 上海师范大学 | 一种pH和乏氧双响应定位肿瘤细胞的萘酰亚胺类比率荧光探针及其合成方法 |
CN110283123B (zh) * | 2019-07-08 | 2022-06-17 | 桂林医学院 | 4-对甲苯磺酰基哌嗪-3-硝基-1,8-萘酰亚胺衍生物及其合成方法和应用 |
CN110272388B (zh) * | 2019-07-08 | 2022-06-17 | 桂林医学院 | 4-二硫代甲酸哌嗪-3-硝基-1,8-萘酰亚胺衍生物及其合成方法和应用 |
CN110407865B (zh) * | 2019-08-02 | 2022-04-15 | 山东师范大学 | 基于苯磺酰胺结构的式(i)化合物及其制备方法与应用 |
CN111518075B (zh) * | 2020-04-17 | 2023-03-28 | 西南大学 | 萘酰亚胺哌嗪三唑类化合物及其制备方法和应用 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2423546C2 (de) * | 1974-05-15 | 1983-01-27 | Hoechst Ag, 6000 Frankfurt | Verfahren zur Herstellung von 4-Amino-1,8- naphthalsäure-N-arylimid-Verbindungen |
ES459497A1 (es) * | 1977-06-04 | 1978-04-16 | Made Labor Sa | Un metodo para la preparacion industrial de naftalimidas y sus derivados. |
DE3635711A1 (de) * | 1986-10-21 | 1988-04-28 | Knoll Ag | 5-nitrobenzo(de)isochinolin-1,3-dione, ihre herstellung und verwendung |
ES2257768T3 (es) * | 1996-10-21 | 2006-08-01 | Nps Allelix Corp. | Antagonistas de neurotropina para el tratamiento de epilepsia, enfermedad de alzheimer y el dolor. |
WO1998018764A1 (de) * | 1996-10-28 | 1998-05-07 | Merck Patent Gmbh | Dihydrobenzoanthracenone, -pyrimidinone oder dihydronaphthochinolinone |
-
1999
- 1999-11-09 CZ CZ20011782A patent/CZ20011782A3/cs unknown
- 1999-11-09 CN CN99813687A patent/CN1330638A/zh active Pending
- 1999-11-09 HU HU0104520A patent/HUP0104520A3/hu unknown
- 1999-11-09 EP EP99968783A patent/EP1144381A2/en not_active Withdrawn
- 1999-11-09 KR KR1020017006547A patent/KR20010080569A/ko not_active Application Discontinuation
- 1999-11-09 ID IDW00200101392A patent/ID28982A/id unknown
- 1999-11-09 JP JP2000585219A patent/JP2002537225A/ja active Pending
- 1999-11-09 AU AU26603/00A patent/AU760136B2/en not_active Ceased
- 1999-11-09 PL PL99348204A patent/PL348204A1/xx unknown
- 1999-11-09 CA CA002352045A patent/CA2352045A1/en not_active Abandoned
- 1999-11-09 SK SK702-2001A patent/SK7022001A3/sk unknown
- 1999-11-09 BR BR9915648-2A patent/BR9915648A/pt not_active IP Right Cessation
- 1999-11-09 WO PCT/EP1999/008561 patent/WO2000032577A2/en not_active Application Discontinuation
- 1999-11-24 TW TW088120540A patent/TW473474B/zh not_active IP Right Cessation
-
2001
- 2001-05-23 NO NO20012544A patent/NO20012544D0/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
BR9915648A (pt) | 2001-08-14 |
CZ20011782A3 (cs) | 2001-09-12 |
WO2000032577A3 (en) | 2000-09-21 |
NO20012544L (no) | 2001-05-23 |
HUP0104520A3 (en) | 2002-10-28 |
JP2002537225A (ja) | 2002-11-05 |
ID28982A (id) | 2001-07-19 |
CA2352045A1 (en) | 2000-06-08 |
SK7022001A3 (en) | 2002-09-10 |
AU760136B2 (en) | 2003-05-08 |
WO2000032577A2 (en) | 2000-06-08 |
CN1330638A (zh) | 2002-01-09 |
PL348204A1 (en) | 2002-05-06 |
EP1144381A2 (en) | 2001-10-17 |
AU2660300A (en) | 2000-06-19 |
KR20010080569A (ko) | 2001-08-22 |
NO20012544D0 (no) | 2001-05-23 |
HUP0104520A2 (hu) | 2002-04-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
TW473474B (en) | Substituted benzo[de]isoquinoline-1,3-diones | |
CN100366605C (zh) | 治疗阿尔茨海默氏症的化合物 | |
TW383307B (en) | Pyridopyrazine derivatives | |
TW420664B (en) | Amino(thio)ether derivatives | |
CN102307872B (zh) | 作为用于治疗癌症和免疫疾病的bcl-2-选择性诱发细胞凋亡药剂的磺酰胺衍生物 | |
TW515792B (en) | N-alkanoylphenylalanine derivatives | |
TW509687B (en) | Novel piperazine derivatives having combined 5HT1A, 5HT1B and 5HT1D recept or antagonist activity and their use for the treatment and prophylaxis of various CNS disorders | |
SG193849A1 (en) | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | |
TWI314555B (en) | Heterocyclic derivatives | |
TW201208686A (en) | Quinoline derivatives and MELK inhibitors containing the same | |
MX2011005925A (es) | Agentes inductores de apoptosis para el tratamiento de cancer, enfermedades inmunes y autoinmunes. | |
TW200403210A (en) | Benzamide derivatives | |
TW201043603A (en) | Substituted phenylureas and phenylamides as vanilloid receptor ligands | |
CN102317257A (zh) | 制备不对称双(缩氨基硫脲)的方法 | |
TW201040162A (en) | Inhibitors of JAK | |
CN103492028A (zh) | 新的磺氨基喹啉铁调素拮抗剂 | |
SE503081C2 (sv) | Förening med relaxationsaktivitet för kärls glatta muskulatur | |
CN101090883A (zh) | 取代羟基乙胺 | |
CN106458868A (zh) | 胍化合物及其用途 | |
TWI283671B (en) | Piperazinylacylpiperidine derivatives, their preparation and therapeutic use thereof | |
JP4845733B2 (ja) | P38キナーゼ阻害剤としての3−アミノカルボニル、6−フェニル置換ピリジン−1−オキシド | |
TWI291955B (en) | Novel indole derivatives and their use as medicaments | |
BR112020021569A2 (pt) | Inibidor da interação proteína-proteína mll1-wdr5 de fenil triazol | |
US11390591B2 (en) | 2,4,6-trisubstituted s-triazine compound, preparation method therefor, and use thereof | |
US6245768B1 (en) | 1-(N′-(arylalkylaminoalkyl)) aminoisoindoles; a new class of dopamine receptor subtype specific ligands |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
GD4A | Issue of patent certificate for granted invention patent | ||
MM4A | Annulment or lapse of patent due to non-payment of fees |