NO20010603L - 2-substituert-1-piperidylbenzimidazol forbindelser som ORL 1- reseptor agonister - Google Patents

2-substituert-1-piperidylbenzimidazol forbindelser som ORL 1- reseptor agonister

Info

Publication number
NO20010603L
NO20010603L NO20010603A NO20010603A NO20010603L NO 20010603 L NO20010603 L NO 20010603L NO 20010603 A NO20010603 A NO 20010603A NO 20010603 A NO20010603 A NO 20010603A NO 20010603 L NO20010603 L NO 20010603L
Authority
NO
Norway
Prior art keywords
alkyl
orl
aromatic
unsubstituted
piperidylbenzimidazole
Prior art date
Application number
NO20010603A
Other languages
English (en)
Norwegian (no)
Other versions
NO20010603D0 (no
Inventor
Fumitaka Ito
Hirohide Noguchi
Hiroshi Kondo
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO20010603D0 publication Critical patent/NO20010603D0/no
Publication of NO20010603L publication Critical patent/NO20010603L/no

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • C07D211/58Nitrogen atoms attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Toxicology (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Addiction (AREA)
  • Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO20010603A 1998-08-06 2001-02-05 2-substituert-1-piperidylbenzimidazol forbindelser som ORL 1- reseptor agonister NO20010603L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IBPCT/IB98/01206 1998-08-06
PCT/IB1999/001239 WO2000008013A2 (en) 1998-08-06 1999-07-05 2-substituted-1-piperidyl benzimidazole compounds as orl1-receptor agonists

Publications (2)

Publication Number Publication Date
NO20010603D0 NO20010603D0 (no) 2001-02-05
NO20010603L true NO20010603L (no) 2001-04-05

Family

ID=11004738

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20010603A NO20010603L (no) 1998-08-06 2001-02-05 2-substituert-1-piperidylbenzimidazol forbindelser som ORL 1- reseptor agonister

Country Status (44)

Country Link
US (1) US6172067B1 (sk)
EP (1) EP1102762B1 (sk)
JP (1) JP3367945B2 (sk)
CN (1) CN1317968A (sk)
AP (1) AP2001002063A0 (sk)
AR (1) AR018686A1 (sk)
AT (1) ATE227716T1 (sk)
AU (1) AU749166B2 (sk)
BG (1) BG105301A (sk)
BR (1) BR9912778A (sk)
CA (1) CA2339621C (sk)
CZ (1) CZ2001397A3 (sk)
DE (1) DE69903953T2 (sk)
DK (1) DK1102762T3 (sk)
EA (1) EA200100104A1 (sk)
EE (1) EE200100075A (sk)
ES (1) ES2185357T3 (sk)
GE (1) GEP20033000B (sk)
GT (1) GT199900125A (sk)
HK (1) HK1040188A1 (sk)
HN (1) HN1999000105A (sk)
HR (1) HRP20010089B1 (sk)
HU (1) HUP0103567A3 (sk)
ID (1) ID27212A (sk)
IL (1) IL141029A0 (sk)
IS (1) IS5812A (sk)
MA (1) MA26659A1 (sk)
NO (1) NO20010603L (sk)
NZ (1) NZ509299A (sk)
OA (1) OA11590A (sk)
PA (1) PA8477701A1 (sk)
PE (1) PE20000868A1 (sk)
PL (1) PL346211A1 (sk)
PT (1) PT1102762E (sk)
SI (1) SI1102762T1 (sk)
SK (1) SK1602001A3 (sk)
SV (1) SV1999000099A (sk)
TN (1) TNSN99142A1 (sk)
TR (1) TR200100403T2 (sk)
TW (1) TW513424B (sk)
UY (1) UY25659A1 (sk)
WO (1) WO2000008013A2 (sk)
YU (1) YU8201A (sk)
ZA (1) ZA200100900B (sk)

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GB0104050D0 (en) 2001-02-19 2001-04-04 Astrazeneca Ab Chemical compounds
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DK1385514T5 (da) 2001-04-18 2009-03-09 Euro Celtique Sa Spiroinden- og spiroindanforbindelser
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US20030040479A1 (en) * 2001-07-02 2003-02-27 Omeros Corporation Rotational intrathecal analgesia method and device
SE0102716D0 (sv) * 2001-08-14 2001-08-14 Astrazeneca Ab Novel compounds
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GB0221828D0 (en) 2002-09-20 2002-10-30 Astrazeneca Ab Novel compound
GB0221829D0 (en) * 2002-09-20 2002-10-30 Astrazeneca Ab Novel compound
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US20090239880A1 (en) * 2006-07-03 2009-09-24 Ulrik Svane Sorensen Combinations of monoamine reuptake inhibitors and potassium channel activators
KR101227072B1 (ko) 2007-01-16 2013-01-29 시오노기세이야쿠가부시키가이샤 Orl-1 리간드로서의 헤테로시클릭-치환 피페리딘
BRPI0815327A2 (pt) * 2007-08-31 2015-12-15 Purdue Pharma Lp "compostos de piperidina do tipo quinoxalina substituída e os usos destes"
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Also Published As

Publication number Publication date
BG105301A (en) 2001-12-29
YU8201A (sh) 2003-07-07
ATE227716T1 (de) 2002-11-15
PA8477701A1 (es) 2000-09-29
NZ509299A (en) 2003-05-30
CN1317968A (zh) 2001-10-17
GT199900125A (es) 2001-01-27
EA200100104A1 (ru) 2001-08-27
IS5812A (is) 2001-01-16
IL141029A0 (en) 2002-02-10
UY25659A1 (es) 2000-02-23
HUP0103567A2 (hu) 2002-02-28
SV1999000099A (es) 2000-09-05
BR9912778A (pt) 2001-09-25
AP2001002063A0 (en) 2001-03-31
OA11590A (en) 2004-08-18
JP3367945B2 (ja) 2003-01-20
AU749166B2 (en) 2002-06-20
TNSN99142A1 (fr) 2005-11-10
DE69903953D1 (de) 2002-12-19
HK1040188A1 (zh) 2002-05-31
PT1102762E (pt) 2003-02-28
NO20010603D0 (no) 2001-02-05
CA2339621C (en) 2005-04-05
EE200100075A (et) 2002-06-17
DK1102762T3 (da) 2002-12-16
PL346211A1 (en) 2002-01-28
DE69903953T2 (de) 2003-03-27
TR200100403T2 (tr) 2001-07-23
PE20000868A1 (es) 2000-08-31
AU4385999A (en) 2000-02-28
EP1102762B1 (en) 2002-11-13
WO2000008013A2 (en) 2000-02-17
CZ2001397A3 (cs) 2002-05-15
WO2000008013A3 (en) 2000-03-23
GEP20033000B (en) 2003-06-25
ZA200100900B (en) 2002-08-28
HUP0103567A3 (en) 2003-01-28
JP2002522431A (ja) 2002-07-23
US6172067B1 (en) 2001-01-09
ES2185357T3 (es) 2003-04-16
TW513424B (en) 2002-12-11
HN1999000105A (es) 2000-11-11
MA26659A1 (fr) 2004-12-20
CA2339621A1 (en) 2000-02-17
AR018686A1 (es) 2001-11-28
ID27212A (id) 2001-03-08
HRP20010089A2 (en) 2002-02-28
SI1102762T1 (en) 2003-04-30
HRP20010089B1 (en) 2003-04-30
SK1602001A3 (en) 2002-09-10
EP1102762A2 (en) 2001-05-30

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