NO20005488L - Hematopoetisk stimulering - Google Patents
Hematopoetisk stimuleringInfo
- Publication number
- NO20005488L NO20005488L NO20005488A NO20005488A NO20005488L NO 20005488 L NO20005488 L NO 20005488L NO 20005488 A NO20005488 A NO 20005488A NO 20005488 A NO20005488 A NO 20005488A NO 20005488 L NO20005488 L NO 20005488L
- Authority
- NO
- Norway
- Prior art keywords
- hematopoietic stimulation
- hematopoietic
- stimulation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Magnetic Treatment Devices (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8412898P | 1998-05-04 | 1998-05-04 | |
PCT/US1999/009652 WO1999056753A1 (en) | 1998-05-04 | 1999-05-03 | Hematopoietic stimulation |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20005488D0 NO20005488D0 (no) | 2000-10-31 |
NO20005488L true NO20005488L (no) | 2001-01-04 |
Family
ID=22183048
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20005488A NO20005488L (no) | 1998-05-04 | 2000-10-31 | Hematopoetisk stimulering |
Country Status (15)
Country | Link |
---|---|
US (4) | US6300314B1 (no) |
EP (1) | EP1075266A1 (no) |
JP (1) | JP2002513762A (no) |
KR (1) | KR20010052302A (no) |
AR (1) | AR023628A1 (no) |
AU (2) | AU770319C (no) |
BR (1) | BR9910251A (no) |
CA (1) | CA2331122A1 (no) |
IL (1) | IL139247A0 (no) |
MY (1) | MY132924A (no) |
NO (1) | NO20005488L (no) |
NZ (1) | NZ507730A (no) |
PE (1) | PE20000481A1 (no) |
TW (1) | TWI252107B (no) |
WO (1) | WO1999056753A1 (no) |
Families Citing this family (77)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR9813233A (pt) * | 1997-09-29 | 2000-08-22 | Point Therapeutics Inc | Estimulação de células hematopoéticas in vitro |
US6300314B1 (en) * | 1998-05-04 | 2001-10-09 | Point Therapeutics, Inc. | Hematopoietic stimulation |
US6979697B1 (en) * | 1998-08-21 | 2005-12-27 | Point Therapeutics, Inc. | Regulation of substrate activity |
US6890904B1 (en) | 1999-05-25 | 2005-05-10 | Point Therapeutics, Inc. | Anti-tumor agents |
EP2322601A1 (en) | 2000-12-06 | 2011-05-18 | Anthrogenesis Corporation | Method of collecting placental stem cells |
US7311905B2 (en) | 2002-02-13 | 2007-12-25 | Anthrogenesis Corporation | Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells |
CA2430967C (en) | 2001-01-16 | 2009-06-23 | Nippon Kayaku Kabushiki Kaisha | Remedies for bone marrow suppression and infectious diseases and white blood cell count elevating agents |
CA2438153C (en) * | 2001-02-14 | 2015-06-02 | Anthrogenesis Corporation | Post-partum mammalian placenta, its use and placental stem cells therefrom |
UA74912C2 (en) | 2001-07-06 | 2006-02-15 | Merck & Co Inc | Beta-aminotetrahydroimidazo-(1,2-a)-pyrazines and tetratriazolo-(4,3-a)-pyrazines as inhibitors of dipeptylpeptidase for the treatment or prevention of diabetes |
US20060014697A1 (en) * | 2001-08-22 | 2006-01-19 | Travis Mickle | Pharmaceutical compositions for prevention of overdose or abuse |
CA2466870A1 (en) * | 2001-11-26 | 2003-06-05 | Trustees Of Tufts College | Methods for treating autoimmune disorders, and reagents related thereto |
US7727964B2 (en) | 2001-11-26 | 2010-06-01 | Trustees Of Tufts College | Peptidomimetic inhibitors of post-proline cleaving enzymes |
EP1554595B1 (en) * | 2001-12-17 | 2008-05-14 | Koninklijke Philips Electronics N.V. | Magnetic resonance method |
US7682803B2 (en) | 2005-10-13 | 2010-03-23 | Anthrogenesis Corporation | Immunomodulation using placental stem cells |
JP2005531540A (ja) | 2002-04-30 | 2005-10-20 | トラスティーズ・オブ・タフツ・カレッジ | セリンプロテアーゼ阻害剤のスマートプロドラッグ |
JP2006506442A (ja) * | 2002-07-09 | 2006-02-23 | ポイント セラピューティクス, インコーポレイテッド | ボロプロリン化合物併用療法 |
KR20050086780A (ko) | 2002-11-26 | 2005-08-30 | 안트로제네시스 코포레이션 | 세포요법제, 세포요법제 단위 및 이를 이용한 치료방법 |
US7638638B2 (en) | 2003-05-14 | 2009-12-29 | Takeda San Diego, Inc. | Dipeptidyl peptidase inhibitors |
US7678909B1 (en) | 2003-08-13 | 2010-03-16 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
US7169926B1 (en) | 2003-08-13 | 2007-01-30 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
PL1689757T3 (pl) * | 2003-11-12 | 2015-05-29 | Sino Med Int Alliance Inc | Heterocykliczne związki kwasu boronowego |
US7767828B2 (en) * | 2003-11-12 | 2010-08-03 | Phenomix Corporation | Methyl and ethyl substituted pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV |
US7576121B2 (en) * | 2003-11-12 | 2009-08-18 | Phenomix Corporation | Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV |
US7317109B2 (en) * | 2003-11-12 | 2008-01-08 | Phenomix Corporation | Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV |
RU2379315C2 (ru) * | 2004-02-23 | 2010-01-20 | Трастиз Оф Тафтс Колледж | Ингибиторы дипептидилпептидазы iv |
US7732446B1 (en) | 2004-03-11 | 2010-06-08 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
US7687638B2 (en) | 2004-06-04 | 2010-03-30 | Takeda San Diego, Inc. | Dipeptidyl peptidase inhibitors |
WO2006019965A2 (en) | 2004-07-16 | 2006-02-23 | Takeda San Diego, Inc. | Dipeptidyl peptidase inhibitors |
US20060063719A1 (en) * | 2004-09-21 | 2006-03-23 | Point Therapeutics, Inc. | Methods for treating diabetes |
WO2006052960A2 (en) * | 2004-11-08 | 2006-05-18 | The General Hospital Corporation | METHODS AND COMPOSITIONS FOR INCREASING STEM CELL HOMING USING Gαs ACTIVATORS |
DOP2006000008A (es) | 2005-01-10 | 2006-08-31 | Arena Pharm Inc | Terapia combinada para el tratamiento de la diabetes y afecciones relacionadas y para el tratamiento de afecciones que mejoran mediante un incremento de la concentración sanguínea de glp-1 |
US7825139B2 (en) * | 2005-05-25 | 2010-11-02 | Forest Laboratories Holdings Limited (BM) | Compounds and methods for selective inhibition of dipeptidyl peptidase-IV |
CN101395266B (zh) | 2005-12-29 | 2018-06-15 | 人类起源公司 | 胎盘干细胞群 |
CN101389754A (zh) | 2005-12-29 | 2009-03-18 | 人类起源公司 | 胎盘干细胞和第二来源干细胞的联合培养 |
WO2007112347A1 (en) | 2006-03-28 | 2007-10-04 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
PE20071221A1 (es) | 2006-04-11 | 2007-12-14 | Arena Pharm Inc | Agonistas del receptor gpr119 en metodos para aumentar la masa osea y para tratar la osteoporosis y otras afecciones caracterizadas por masa osea baja, y la terapia combinada relacionada a estos agonistas |
AU2008210988B2 (en) * | 2007-02-01 | 2012-09-06 | Allocure, Inc. | Potentiation of stem cell homing and treatment of organ dysfunction or organ failure |
US20080195007A1 (en) * | 2007-02-12 | 2008-08-14 | Yury Podrazhansky | Method and device for using vibroacoustic stimulaton to enhance the production of adult stem cells in living organisms |
EP2630959A1 (en) | 2007-02-12 | 2013-08-28 | Anthrogenesis Corporation | Treatment of inflammatory diseases using placental stem cells |
US7674691B2 (en) * | 2007-03-07 | 2010-03-09 | International Business Machines Corporation | Method of manufacturing an electrical antifuse |
US9200253B1 (en) | 2007-08-06 | 2015-12-01 | Anthrogenesis Corporation | Method of producing erythrocytes |
KR20210127819A (ko) | 2007-09-28 | 2021-10-22 | 안트로제네시스 코포레이션 | 인간 태반 관류액 및 인간 태반-유래 중간체 천연 킬러 세포를 사용한 종양 억제 방법 |
EP2146210A1 (en) | 2008-04-07 | 2010-01-20 | Arena Pharmaceuticals, Inc. | Methods of using A G protein-coupled receptor to identify peptide YY (PYY) secretagogues and compounds useful in the treatment of conditions modulated by PYY |
RU2558778C2 (ru) | 2008-08-20 | 2015-08-10 | Антродженезис Корпорейшн | Лечение инсульта с использованием изолированных плацентарных клеток |
KR20210010648A (ko) | 2008-08-20 | 2021-01-27 | 안트로제네시스 코포레이션 | 개선된 세포 조성물 및 그의 제조 방법 |
EP2331109B1 (en) | 2008-08-22 | 2013-05-29 | Anthrogenesis Corporation | Methods and compositions for treatment of bone defects with placental cell populations |
JO2870B1 (en) | 2008-11-13 | 2015-03-15 | ميرك شارب اند دوهم كورب | Amino Tetra Hydro Pirans as Inhibitors of Peptide Dipeptide IV for the Treatment or Prevention of Diabetes |
EP2367932B1 (en) | 2008-11-19 | 2019-06-12 | Celularity, Inc. | Amnion derived adherent cells |
CA2767014C (en) | 2009-07-02 | 2022-01-25 | Anthrogenesis Corporation | Method of producing erythrocytes without feeder cells |
AR077642A1 (es) | 2009-07-09 | 2011-09-14 | Arena Pharm Inc | Moduladores del metabolismo y el tratamiento de trastornos relacionados con el mismo |
CA2771352A1 (en) | 2009-09-02 | 2011-03-10 | Merck Sharp & Dohme Corp. | Aminotetrahydropyrans as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes |
WO2011079778A1 (en) | 2009-12-30 | 2011-07-07 | China Shanghai Fochon Pharmaceutical Co Ltd | 3-(3-aminopiperidin-1-yl)-5-oxo-1,2,4-triazine derivates as dipeptidyl peptidase iv(dpp-iv) inhibitors |
WO2011094181A1 (en) | 2010-01-26 | 2011-08-04 | Anthrogenesis Corporation | Treatment of bone-related cancers using placental stem cells |
EP2538783B1 (en) | 2010-02-22 | 2016-06-01 | Merck Sharp & Dohme Corp. | Substituted aminotetrahydrothiopyrans and derivatives thereof as dipeptidyl peptidase-iv inhibitors for the treatment of diabetes |
CN102918027A (zh) | 2010-04-06 | 2013-02-06 | 艾尼纳制药公司 | Gpr119受体调节剂和对与所述受体有关的障碍的治疗 |
CN107699541A (zh) | 2010-04-07 | 2018-02-16 | 人类起源公司 | 使用胎盘干细胞的血管生成 |
MX2012011543A (es) | 2010-04-08 | 2013-05-06 | Anthrogenesis Corp | Tratamiento de sarcoidosis empleando celulas madre placentarias. |
WO2011146358A1 (en) | 2010-05-21 | 2011-11-24 | Merck Sharp & Dohme Corp. | Substituted seven-membered heterocyclic compounds as dipeptidyl peptidase-iv inhibitors for the treatment of diabetes |
KR20200077613A (ko) | 2010-07-13 | 2020-06-30 | 안트로제네시스 코포레이션 | 천연 킬러 세포의 생성 방법 |
BR112013008100A2 (pt) | 2010-09-22 | 2016-08-09 | Arena Pharm Inc | "moduladores do receptor de gpr19 e o tratamento de distúrbios relacionados a eles." |
WO2012092485A1 (en) | 2010-12-31 | 2012-07-05 | Anthrogenesis Corporation | Enhancement of placental stem cell potency using modulatory rna molecules |
WO2012135570A1 (en) | 2011-04-01 | 2012-10-04 | Arena Pharmaceuticals, Inc. | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
US20140066369A1 (en) | 2011-04-19 | 2014-03-06 | Arena Pharmaceuticals, Inc. | Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto |
US20140038889A1 (en) | 2011-04-22 | 2014-02-06 | Arena Pharmaceuticals, Inc. | Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto |
US20140051714A1 (en) | 2011-04-22 | 2014-02-20 | Arena Pharmaceuticals, Inc. | Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto |
ES2707579T3 (es) | 2011-06-01 | 2019-04-04 | Celularity Inc | Tratamiento del dolor usando citoblastos placentarios |
WO2012170702A1 (en) | 2011-06-08 | 2012-12-13 | Arena Pharmaceuticals, Inc. | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
HUE060305T2 (hu) | 2011-08-30 | 2023-02-28 | Tufts College | FAP-aktivált proteaszóma inhibitorok a szolid tumorok kezelésére |
US9925221B2 (en) | 2011-09-09 | 2018-03-27 | Celularity, Inc. | Treatment of amyotrophic lateral sclerosis using placental stem cells |
WO2013055910A1 (en) | 2011-10-12 | 2013-04-18 | Arena Pharmaceuticals, Inc. | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
WO2013078286A1 (en) | 2011-11-22 | 2013-05-30 | Cornell University | Methods for stimulating hematopoietic recovery by inhibiting tgf beta signaling |
EP2814485A4 (en) | 2012-02-17 | 2015-08-26 | Merck Sharp & Dohme | DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES |
US9315508B2 (en) | 2012-07-23 | 2016-04-19 | Merck Sharp & Dohme Corp. | Treating diabetes with dipeptidyl peptidase-IV inhibitors |
WO2014074668A1 (en) | 2012-11-08 | 2014-05-15 | Arena Pharmaceuticals, Inc. | Modulators of gpr119 and the treatment of disorders related thereto |
JP2016506968A (ja) | 2013-02-05 | 2016-03-07 | アントフロゲネシス コーポレーション | 胎盤由来のナチュラルキラー細胞 |
AU2016229982B2 (en) | 2015-03-09 | 2020-06-18 | Intekrin Therapeutics, Inc. | Methods for the treatment of nonalcoholic fatty liver disease and/or lipodystrophy |
EP3606527A1 (en) | 2017-04-03 | 2020-02-12 | Coherus Biosciences, Inc. | Ppar-gamma agonist for treatment of progressive supranuclear palsy |
Family Cites Families (77)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE270382C (no) | ||||
DE296075C (no) | ||||
DE158109C (no) | ||||
US4318904A (en) | 1980-04-25 | 1982-03-09 | Research Corporation | Peptide affinity labels for thrombin and other trypsin-like proteases |
US4443609A (en) | 1980-05-19 | 1984-04-17 | Petrolite Corporation | Tetrahydrothiazole phosphonic acids or esters thereof |
DD158109A1 (de) | 1981-04-10 | 1982-12-29 | Gunter Fischer | Verfahren zur hemmung der katalytischen aktivitaet von peptidhydrolasen |
US4582821A (en) | 1983-11-16 | 1986-04-15 | E. I. Du Pont De Nemours And Company | Inhibition of cyclic nucleotide independent protein kinases |
US4499082A (en) | 1983-12-05 | 1985-02-12 | E. I. Du Pont De Nemours And Company | α-Aminoboronic acid peptides |
US4636492A (en) | 1984-08-29 | 1987-01-13 | E. I. Du Pont De Nemours And Company | Inhibition of viral protease activity by peptide halomethyl ketones |
US4652552A (en) | 1984-09-10 | 1987-03-24 | E. I. Du Pont De Nemours And Company | Tetrapeptide methyl ketone inhibitors of viral proteases |
US4644055A (en) | 1984-12-17 | 1987-02-17 | E. I. Du Pont De Nemours And Company | Method for preparing specific inhibitors of virus-specified proteases |
US4664262A (en) * | 1985-11-26 | 1987-05-12 | White Pamela J | Pill dispensing system |
DD270382A1 (de) | 1986-10-31 | 1989-07-26 | Univ Halle Wittenberg | Verfahren zur kolorimetrischen bestimmung von dipeptidylpeptidase iv mittels dipeptidhydraziden |
US5187157A (en) | 1987-06-05 | 1993-02-16 | Du Pont Merck Pharmaceutical Company | Peptide boronic acid inhibitors of trypsin-like proteases |
US5250720A (en) | 1987-06-05 | 1993-10-05 | The Dupont Merck Pharmaceutical Company | Intermediates for preparing peptide boronic acid inhibitors of trypsin-like proteases |
US5242904A (en) | 1987-06-05 | 1993-09-07 | The Dupont Merck Pharmaceutical Company | Peptide boronic acid inhibitors of trypsin-like proteases |
US4935493A (en) | 1987-10-06 | 1990-06-19 | E. I. Du Pont De Nemours And Company | Protease inhibitors |
AU2613988A (en) | 1988-01-04 | 1989-08-01 | E.I. Du Pont De Nemours And Company | Multiple stage affinity process for isolation of specific cells from a cell mixture |
US4963655A (en) | 1988-05-27 | 1990-10-16 | Mayo Foundation For Medical Education And Research | Boron analogs of amino acid/peptide protease inhibitors |
US5215926A (en) | 1988-06-03 | 1993-06-01 | Cellpro, Inc. | Procedure for designing efficient affinity cell separation processes |
DE68924850T2 (de) | 1988-06-14 | 1996-10-10 | Cell Med Inc | Heterofunktionelle zellular immunologische reagenzien, impfstoffe daraus und verwendungsverfahren. |
IL91307A0 (en) | 1988-08-24 | 1990-03-19 | Merck & Co Inc | Hiv protease inhibitors and pharmaceutical compositions for the treatment of aids containing them |
DE3840452A1 (de) | 1988-12-01 | 1990-06-07 | Hoechst Ag | (beta)-amino-boronsaeure-derivate |
DE3842197A1 (de) | 1988-12-15 | 1990-06-21 | Hoechst Ag | Rasch spaltbares substrat fuer die hiv-protease |
US5437994A (en) | 1989-06-15 | 1995-08-01 | Regents Of The University Of Michigan | Method for the ex vivo replication of stem cells, for the optimization of hematopoietic progenitor cell cultures, and for increasing the metabolism, GM-CSF secretion and/or IL-6 secretion of human stromal cells |
US5635386A (en) | 1989-06-15 | 1997-06-03 | The Regents Of The University Of Michigan | Methods for regulating the specific lineages of cells produced in a human hematopoietic cell culture |
DD296075A5 (de) | 1989-08-07 | 1991-11-21 | Martin-Luther-Universitaet Halle-Wittenberg,De | Verfahren zur herstellung neuer inhibitoren der dipeptidyl peptidase iv |
DE4033062A1 (de) | 1990-10-18 | 1992-04-23 | Merck Patent Gmbh | Aminosaeurederivate |
US5462928A (en) | 1990-04-14 | 1995-10-31 | New England Medical Center Hospitals, Inc. | Inhibitors of dipeptidyl-aminopeptidase type IV |
ES2099158T3 (es) | 1990-04-14 | 1997-05-16 | New England Medical Center Inc | Tratamiento del rechazo de trasplantes o de enfermedades autoinmunitarias y complejo de la formula general x-pro-y-boropro asociada al mismo. |
US5378624A (en) | 1990-04-23 | 1995-01-03 | Cellpro, Incorporated | Methods for removing ligands from a particle surface |
US5635387A (en) | 1990-04-23 | 1997-06-03 | Cellpro, Inc. | Methods and device for culturing human hematopoietic cells and their precursors |
WO1991017767A1 (en) | 1990-05-21 | 1991-11-28 | New England Medical Center Hospitals, Inc. | Method of treating inhibition of dipeptidyl aminopeptidase type iv |
GB9017694D0 (en) | 1990-08-13 | 1990-09-26 | Sandoz Ltd | Improvements in or relating to organic chemistry |
US5288707A (en) | 1990-08-13 | 1994-02-22 | Sandoz Ltd. | Borolysine peptidomimetics |
FR2668069B1 (fr) * | 1990-10-18 | 1993-02-05 | Dassault Avions | Dispositif, notamment autonome et portable, pour extraire de la chaleur d'une source chaude. |
JPH06504547A (ja) | 1990-12-28 | 1994-05-26 | ジョージア・テック・リサーチ・コーポレーション | ペプチドケトアミド、ケト酸およびケトエステル |
WO1992017490A1 (en) | 1991-04-04 | 1992-10-15 | The Upjohn Company | Phosphorus containing compounds as inhibitors of retroviruses |
IE922316A1 (en) | 1991-07-17 | 1993-01-27 | Smithkline Beecham Corp | Retroviral protease inhibitors |
US5554728A (en) | 1991-07-23 | 1996-09-10 | Nexstar Pharmaceuticals, Inc. | Lipid conjugates of therapeutic peptides and protease inhibitors |
AU2468392A (en) | 1991-08-29 | 1993-04-05 | Cytel Corporation | Novel immunosuppressants |
US6825169B1 (en) * | 1991-10-22 | 2004-11-30 | Trustees Of Tufts College | Inhibitors of dipeptidyl-aminopeptidase type IV |
CA2121369C (en) | 1991-10-22 | 2003-04-29 | William W. Bachovchin | Inhibitors of dipeptidyl-aminopeptidase type iv |
MX9206628A (es) | 1991-11-22 | 1993-05-01 | Boehringer Ingelheim Pharma | Ester de prolinaboronato y metodo para su preparacion. |
WO1993016102A1 (en) | 1992-02-06 | 1993-08-19 | Dana-Farber Cancer Institute, Inc. | Human cd26 and methods for use |
US5296604A (en) | 1992-05-15 | 1994-03-22 | Miles Inc. | Proline derivatives and compositions for their use as inhibitors of HIV protease |
WO1994003055A1 (en) * | 1992-07-31 | 1994-02-17 | The Government Of The United States Of America, Asrepresented By The Secretary Of The Department Of Health And Human Services | Producing increased numbers of hematopoietic cells by administering inhibitors of dipeptidyl peptidase iv |
US5329028A (en) | 1992-08-05 | 1994-07-12 | Genentech, Inc. | Carbohydrate-directed cross-linking reagents |
WO1994009132A1 (en) | 1992-08-21 | 1994-04-28 | Dana-Farber Cancer Institute, Inc. | Human cd26 and methods for use |
FR2701951B1 (fr) | 1993-02-24 | 1995-06-09 | Adir | Nouveaux derives peptidiques de l'acide boronique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
CA2153656A1 (en) | 1993-03-03 | 1994-09-15 | Nigel Scott Cook | Peptide boronic acid derivatives having protease inhibiting activity |
US5384410A (en) | 1993-03-24 | 1995-01-24 | The Du Pont Merck Pharmaceutical Company | Removal of boronic acid protecting groups by transesterification |
WO1994025873A1 (en) | 1993-04-23 | 1994-11-10 | Cellpro, Incorporated | Methods for enriching fetal progenitor cells from maternal blood |
SE9301911D0 (sv) | 1993-06-03 | 1993-06-03 | Ab Astra | New peptide derivatives |
FR2707170A1 (fr) | 1993-06-04 | 1995-01-13 | Pasteur Institut | Expression des récepteurs CD4 et CD26 dans des cellules recombinantes, inhibiteurs du récepteur CD26. |
WO1995011689A1 (en) * | 1993-10-29 | 1995-05-04 | Trustees Of Tufts College | Use of inhibitors of dipeptidyl-aminopeptidase to block entry of hiv into cells |
NL9400309A (nl) | 1993-11-04 | 1995-06-01 | Eurogenetics Nv | Ligande die in staat is te binden aan de adenosine deaminase bindingsplaats van CD26. |
IL111785A0 (en) | 1993-12-03 | 1995-01-24 | Ferring Bv | Dp-iv inhibitors and pharmaceutical compositions containing them |
US5489025A (en) * | 1994-03-01 | 1996-02-06 | Romick; Jerome M. | Unit-dose medication dispenser and multiple-dispenser frame therefor |
FR2719049B1 (fr) | 1994-04-22 | 1996-06-14 | Pasteur Institut | Multireprésentation d'un analogue peptidique du substrat de la DPPIV, notamment de type KPR, afin d'inhiber l'entrée du HIV dans les cellules. |
US5543396A (en) | 1994-04-28 | 1996-08-06 | Georgia Tech Research Corp. | Proline phosphonate derivatives |
DE4416963C1 (de) | 1994-05-13 | 1995-07-13 | Boehringer Ingelheim Kg | Verfahren zur Herstellung von enantiomerenreinen Diarylprolinolen |
AU2790895A (en) | 1994-06-10 | 1996-01-05 | Universitaire Instelling Antwerpen | Purification of serine protease and synthetic inhibitors thereof |
FR2721611B1 (fr) | 1994-06-22 | 1996-09-27 | Adir | Nouveaux dérivés peptidiques de l'acide boronique, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent . |
EP0793504B1 (en) * | 1994-12-12 | 2005-06-08 | Beth Israel Deaconess Medical Center, Inc. | Chimeric cytokines and uses thereof |
US5856571A (en) | 1995-06-07 | 1999-01-05 | Cellpro, Incorporated | Semicarbazide-containing linker compounds for formation of stably-linked conjugates and methods related thereto |
ATE204322T1 (de) | 1995-06-07 | 2001-09-15 | Aastrom Biosciences Inc | Vorrichtung und verfahren zum aufbewahren und zur züchtung biologischer zellen |
DE69523956T2 (de) * | 1995-12-29 | 2002-07-18 | Alg Company, Marlborough | Vermehrung von knochenmarksstützzellen |
US5965532A (en) | 1996-06-28 | 1999-10-12 | Trustees Of Tufts College | Multivalent compounds for crosslinking receptors and uses thereof |
GB9624562D0 (en) * | 1996-11-27 | 1997-01-15 | Zeneca Ltd | Peptide derivatives |
US6040145A (en) | 1997-05-07 | 2000-03-21 | Tufts University | Potentiation of the immune response |
US6100234A (en) * | 1997-05-07 | 2000-08-08 | Tufts University | Treatment of HIV |
BR9813233A (pt) | 1997-09-29 | 2000-08-22 | Point Therapeutics Inc | Estimulação de células hematopoéticas in vitro |
US6300314B1 (en) * | 1998-05-04 | 2001-10-09 | Point Therapeutics, Inc. | Hematopoietic stimulation |
IL141471A0 (en) | 1998-08-21 | 2002-03-10 | Point Therapeutics Inc | Regulation of substrate activity |
US6890904B1 (en) | 1999-05-25 | 2005-05-10 | Point Therapeutics, Inc. | Anti-tumor agents |
JP2006506442A (ja) | 2002-07-09 | 2006-02-23 | ポイント セラピューティクス, インコーポレイテッド | ボロプロリン化合物併用療法 |
-
1999
- 1999-05-03 US US09/304,199 patent/US6300314B1/en not_active Expired - Fee Related
- 1999-05-03 NZ NZ507730A patent/NZ507730A/xx unknown
- 1999-05-03 EP EP99921617A patent/EP1075266A1/en not_active Withdrawn
- 1999-05-03 CA CA002331122A patent/CA2331122A1/en not_active Abandoned
- 1999-05-03 MY MYPI99001736A patent/MY132924A/en unknown
- 1999-05-03 WO PCT/US1999/009652 patent/WO1999056753A1/en not_active Application Discontinuation
- 1999-05-03 KR KR1020007012223A patent/KR20010052302A/ko active Search and Examination
- 1999-05-03 AU AU38781/99A patent/AU770319C/en not_active Ceased
- 1999-05-03 IL IL13924799A patent/IL139247A0/xx unknown
- 1999-05-03 JP JP2000546778A patent/JP2002513762A/ja active Pending
- 1999-05-03 TW TW088107193A patent/TWI252107B/zh not_active IP Right Cessation
- 1999-05-03 BR BR9910251-0A patent/BR9910251A/pt not_active Application Discontinuation
- 1999-05-04 AR ARP990102086A patent/AR023628A1/es unknown
- 1999-05-04 PE PE1999000365A patent/PE20000481A1/es not_active Application Discontinuation
-
2000
- 2000-10-31 NO NO20005488A patent/NO20005488L/no not_active Application Discontinuation
-
2001
- 2001-06-11 US US09/878,792 patent/US6770628B2/en not_active Expired - Fee Related
-
2004
- 2004-05-19 AU AU2004202138A patent/AU2004202138A1/en not_active Abandoned
- 2004-06-28 US US10/879,479 patent/US7067489B2/en not_active Expired - Fee Related
-
2006
- 2006-06-26 US US11/474,929 patent/US20070135354A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AR023628A1 (es) | 2002-09-04 |
IL139247A0 (en) | 2001-11-25 |
WO1999056753A1 (en) | 1999-11-11 |
KR20010052302A (ko) | 2001-06-25 |
US6300314B1 (en) | 2001-10-09 |
PE20000481A1 (es) | 2000-06-13 |
US20050037976A1 (en) | 2005-02-17 |
US7067489B2 (en) | 2006-06-27 |
TWI252107B (en) | 2006-04-01 |
AU770319B2 (en) | 2004-02-19 |
JP2002513762A (ja) | 2002-05-14 |
AU770319C (en) | 2004-11-25 |
BR9910251A (pt) | 2001-01-02 |
NZ507730A (en) | 2004-02-27 |
AU3878199A (en) | 1999-11-23 |
AU2004202138A1 (en) | 2004-06-10 |
US6770628B2 (en) | 2004-08-03 |
MY132924A (en) | 2007-10-31 |
NO20005488D0 (no) | 2000-10-31 |
CA2331122A1 (en) | 1999-11-11 |
EP1075266A1 (en) | 2001-02-14 |
US20070135354A1 (en) | 2007-06-14 |
US20020013279A1 (en) | 2002-01-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20005488L (no) | Hematopoetisk stimulering | |
DE69916691D1 (de) | Herzschrittmacher | |
DE59914158D1 (de) | Metallocenmonohalogenide | |
ATE341990T1 (de) | Sigmidoskop | |
FI980132A0 (fi) | Adapterande efterfilter | |
DE59911453D1 (de) | Aktivkohlefilter | |
DE69808145D1 (de) | Tintenbehälternachfüllsystem | |
DE59912371D1 (de) | Gleitschalungsfertiger | |
DE69812868D1 (de) | Flanschreformierungsanlage | |
DE59907306D1 (de) | Fadenchangierung | |
DE59906931D1 (de) | Exzenterzahnradgetriebe | |
DE59911683D1 (de) | Fahrzeugschliessanlage | |
DE69811890D1 (de) | Einzellenkalorimeter | |
DE59908968D1 (de) | Benzoylpyridazine | |
DE59913393D1 (de) | Fadenchangierung | |
DE59903966D1 (de) | Exzenterzahnradgetriebe | |
DE59908769D1 (de) | N-arylsulfonyl-aminosäure-omega-amide | |
DK0969233T3 (da) | Strömningsbegrænser | |
DE59903106D1 (de) | Tripode-gleichlaufdrehgelenk | |
DE69820261D1 (de) | Steuerventilanordnnung | |
DE59908057D1 (de) | Underdruckhandhabungseinrichung | |
DE59901046D1 (de) | Methylcyclotetradec-5-en-1-one | |
DE69809804D1 (de) | Notlaufgeländereifen | |
DE59807217D1 (de) | Nadellager | |
FI980759A0 (fi) | Taetningskonstruktion foer suglaodan i en sugvals |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |