NO20005479D0 - SPLA2-hemmende forbindelser til behandling av sykdom - Google Patents

SPLA2-hemmende forbindelser til behandling av sykdom

Info

Publication number
NO20005479D0
NO20005479D0 NO20005479A NO20005479A NO20005479D0 NO 20005479 D0 NO20005479 D0 NO 20005479D0 NO 20005479 A NO20005479 A NO 20005479A NO 20005479 A NO20005479 A NO 20005479A NO 20005479 D0 NO20005479 D0 NO 20005479D0
Authority
NO
Norway
Prior art keywords
disease
treatment
inhibitory compounds
spla2
spla2 inhibitory
Prior art date
Application number
NO20005479A
Other languages
English (en)
Other versions
NO20005479L (no
Inventor
William Louis Macias
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NO20005479D0 publication Critical patent/NO20005479D0/no
Publication of NO20005479L publication Critical patent/NO20005479L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/22Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an aralkyl radical attached to the ring nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO20005479A 1998-05-01 2000-10-31 sPLA2-hemmende forbindelser til behandling av sykdom NO20005479L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8387498P 1998-05-01 1998-05-01
PCT/US1999/008654 WO1999057100A1 (en) 1998-05-01 1999-04-20 Spla2 inhibitor compounds for treatment of disease

Publications (2)

Publication Number Publication Date
NO20005479D0 true NO20005479D0 (no) 2000-10-31
NO20005479L NO20005479L (no) 2000-12-20

Family

ID=22181224

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20005479A NO20005479L (no) 1998-05-01 2000-10-31 sPLA2-hemmende forbindelser til behandling av sykdom

Country Status (20)

Country Link
US (1) US6340699B1 (no)
EP (1) EP1084108A4 (no)
JP (1) JP2002513783A (no)
KR (1) KR20010043190A (no)
CN (1) CN1299348A (no)
AU (1) AU3656299A (no)
BR (1) BR9910095A (no)
CA (1) CA2330856A1 (no)
CZ (1) CZ20004052A3 (no)
EA (1) EA200001140A1 (no)
HR (1) HRP20000739A2 (no)
HU (1) HUP0102243A2 (no)
ID (1) ID27153A (no)
IL (1) IL139019A0 (no)
NO (1) NO20005479L (no)
PL (1) PL343708A1 (no)
SK (1) SK16342000A3 (no)
TR (1) TR200003194T2 (no)
WO (1) WO1999057100A1 (no)
ZA (1) ZA200005563B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19962300A1 (de) * 1999-12-23 2001-06-28 Asta Medica Ag Substituierte N-Benzyl-Indol-3-yl-glyoxylsäure-Derivate mit Antitumorwirkung
WO2001055108A2 (en) * 2000-01-25 2001-08-02 Eli Lilly And Company Use of spl a2 inhibitors for the treatment of inflammation
JPWO2002000621A1 (ja) 2000-06-29 2004-04-22 塩野義製薬株式会社 X型sPLA2阻害作用を有する化合物
AU2002224531B2 (en) * 2000-07-24 2005-08-25 Dow Global Technologies Inc. Thermoplastic superabsorbent polymer blend compositions and their preparation
CA2627353A1 (en) * 2005-11-03 2007-05-18 Ilypsa, Inc. Indole compounds having c4-acidic substituents and use thereof as phospholipase-a2 inhibitors
CA2720275A1 (en) * 2008-04-01 2009-10-08 Astellas Pharma Inc. Indolinone compound
NZ789295A (en) 2009-04-29 2024-02-23 Amarin Pharmaceuticals Ie Ltd Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same
US9290752B2 (en) 2013-03-13 2016-03-22 Sunny Delight Beverages Co. Process for enhancing the amylase inhibitory efficacy from phaseolus vulgaris extracts

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5356919A (en) 1991-05-30 1994-10-18 G. D. Searle & Co. Leukotriene B4 synthesis inhibitors
DE4218096A1 (de) 1992-06-02 1993-12-09 Boehringer Mannheim Gmbh Spiro-oxetane, Verfahren zu ihrer Herstellung und Arzneimittel
DE4323409A1 (de) 1993-07-13 1995-01-19 Boehringer Mannheim Gmbh Verwendung von Cumarinen und Carbostyrilen als PLA¶2¶-Inhibitoren, neue Cumarine und Carbostyrile, Verfahren zu ihrer Herstellung und Arzneimittel
CZ82295A3 (en) 1994-04-01 1995-12-13 Lilly Co Eli Derivative of 1h-indole-3-glyoxylamide and a pharmaceutical composition containing thereof
WO1995033462A1 (en) * 1994-06-02 1995-12-14 Smithkline Beecham Corporation Anti-inflammatory compounds
NZ298145A (en) * 1994-12-29 1998-08-26 Yamanouchi Pharma Co Ltd Monoclonal antibodies having inhibitory effect on type ii phospholipase a2, proteins forming part thereof, cells producing them, dna encoding them, recombinant vector comprising the dna and medicament
TR199900956T2 (xx) 1996-10-30 1999-07-21 Eli Lilly And Company S�bstit�e edilmi� trisiklik bile�imler.
EA003876B1 (ru) * 1998-02-25 2003-10-30 Дженетикс Инститьют, Ллс Ингибиторы фосфолипазных ферментов

Also Published As

Publication number Publication date
PL343708A1 (en) 2001-08-27
CZ20004052A3 (cs) 2002-05-15
BR9910095A (pt) 2000-12-26
WO1999057100A1 (en) 1999-11-11
SK16342000A3 (sk) 2002-04-04
EP1084108A4 (en) 2005-01-12
KR20010043190A (ko) 2001-05-25
AU3656299A (en) 1999-11-23
HUP0102243A2 (hu) 2001-10-28
CA2330856A1 (en) 1999-11-11
EP1084108A1 (en) 2001-03-21
NO20005479L (no) 2000-12-20
ID27153A (id) 2001-03-08
TR200003194T2 (tr) 2001-03-21
ZA200005563B (en) 2002-01-10
EA200001140A1 (ru) 2001-04-23
HRP20000739A2 (en) 2001-10-31
IL139019A0 (en) 2001-11-25
US6340699B1 (en) 2002-01-22
CN1299348A (zh) 2001-06-13
JP2002513783A (ja) 2002-05-14

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application