NO20001045D0 - Nye cycliske tetrapeptidderivater og medisinsk anvendelse derav - Google Patents

Nye cycliske tetrapeptidderivater og medisinsk anvendelse derav

Info

Publication number
NO20001045D0
NO20001045D0 NO20001045A NO20001045A NO20001045D0 NO 20001045 D0 NO20001045 D0 NO 20001045D0 NO 20001045 A NO20001045 A NO 20001045A NO 20001045 A NO20001045 A NO 20001045A NO 20001045 D0 NO20001045 D0 NO 20001045D0
Authority
NO
Norway
Prior art keywords
medical use
cyclic tetrapeptide
new cyclic
tetrapeptide derivatives
derivatives
Prior art date
Application number
NO20001045A
Other languages
English (en)
Other versions
NO20001045L (no
Inventor
Norikazu Nishino
Minoru Yoshida
Sueharu Horinouchi
Yasuhiko Komatsu
Tsutomu Mimoto
Original Assignee
Japan Energy Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Energy Corp filed Critical Japan Energy Corp
Publication of NO20001045D0 publication Critical patent/NO20001045D0/no
Publication of NO20001045L publication Critical patent/NO20001045L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/12—Cyclic peptides with only normal peptide bonds in the ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/12—Cyclic peptides with only normal peptide bonds in the ring
    • C07K5/126—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO20001045A 1997-09-02 2000-03-01 Nye cycliske tetrapeptidderivater og medisinsk anvendelse derav NO20001045L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP23748197 1997-09-02
JP6327098 1998-03-13
PCT/JP1998/003893 WO1999011659A1 (fr) 1997-09-02 1998-09-01 Derives tetrapeptides cycliques et leur utilisation medicinale

Publications (2)

Publication Number Publication Date
NO20001045D0 true NO20001045D0 (no) 2000-03-01
NO20001045L NO20001045L (no) 2000-04-27

Family

ID=26404362

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20001045A NO20001045L (no) 1997-09-02 2000-03-01 Nye cycliske tetrapeptidderivater og medisinsk anvendelse derav

Country Status (9)

Country Link
US (1) US6399568B1 (no)
EP (1) EP1010705A4 (no)
JP (1) JP3494624B2 (no)
KR (1) KR20010023449A (no)
AU (1) AU732299B2 (no)
CA (1) CA2302451A1 (no)
NO (1) NO20001045L (no)
NZ (1) NZ503061A (no)
WO (1) WO1999011659A1 (no)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6822267B1 (en) * 1997-08-20 2004-11-23 Advantest Corporation Signal transmission circuit, CMOS semiconductor device, and circuit board
JP4269041B2 (ja) * 1999-03-02 2009-05-27 国立大学法人九州工業大学 新規な環状テトラペプチド誘導体とその医薬用途
JP2003505417A (ja) * 1999-07-23 2003-02-12 メルク エンド カムパニー インコーポレーテッド アピシジン誘導環状テトラペプチド類
EA200601252A1 (ru) 1999-09-08 2006-10-27 Слоан-Кеттеринг Инститьют Фор Кэнсер Рисёч Новый класс веществ, вызывающих дифференцировку клеток и являющихся ингибиторами гистондеацетилазы, и способы их применения
BR0016154A (pt) 1999-12-08 2003-02-25 Xcyte Therapies Inc Depsipeptida e seus congêneres papa uso como imunossupressores
US6828302B1 (en) 1999-12-08 2004-12-07 Xcyte Therapies, Inc. Therapeutic uses of depsipeptides and congeners thereof
US6458589B1 (en) 2000-04-27 2002-10-01 Geron Corporation Hepatocyte lineage cells derived from pluripotent stem cells
CA2457043A1 (en) 2001-08-21 2003-02-27 Fujisawa Pharmaceutical Co., Ltd. Medicinal use of histone deacetylase inhibitor and method of evaluating antitumor effect thereof
JP2005517683A (ja) * 2001-12-28 2005-06-16 藤沢薬品工業株式会社 環状テトラペプチド化合物およびその用途
WO2003070754A1 (fr) * 2002-02-20 2003-08-28 Minoru Yoshida Inhibiteurs d'histone desacetylase et procede de production de ces inhibiteurs
US7154002B1 (en) 2002-10-08 2006-12-26 Takeda San Diego, Inc. Histone deacetylase inhibitors
US7250514B1 (en) 2002-10-21 2007-07-31 Takeda San Diego, Inc. Histone deacetylase inhibitors
WO2004046312A2 (en) * 2002-11-15 2004-06-03 The Board Of Trustees Of The University Of Illinois Methods for in vitro expansion of hematopoietic stem cells
JP2006520796A (ja) 2003-03-17 2006-09-14 タケダ サン ディエゴ インコーポレイテッド ヒストンデアセチラーゼインヒビター
JP4550738B2 (ja) * 2003-06-20 2010-09-22 独立行政法人理化学研究所 ヒストン脱アセチル化酵素阻害剤およびその製造方法
EP1824831A2 (en) 2004-12-16 2007-08-29 Takeda San Diego, Inc. Histone deacetylase inhibitors
WO2006122319A2 (en) 2005-05-11 2006-11-16 Takeda San Diego, Inc. Histone deacetylase inhibitors
JP2009501236A (ja) 2005-07-14 2009-01-15 タケダ サン ディエゴ インコーポレイテッド ヒストンデアセチラーゼ阻害剤
EP1801115A1 (en) * 2005-12-23 2007-06-27 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Cyclic peptides and their use in treating advanced stage neuroblastoma
JP2007262058A (ja) * 2006-03-03 2007-10-11 Tokyo Univ Of Science 糸状菌の分化抑制剤
EP2012801A4 (en) 2006-04-24 2009-08-05 Gloucester Pharmaceuticals Inc GEMCITABINE COMBINATION THERAPY
WO2007146730A2 (en) 2006-06-08 2007-12-21 Gloucester Pharmaceuticals Deacetylase inhibitor therapy
WO2008029565A1 (fr) 2006-09-05 2008-03-13 Kyushu Institute Of Technology Composé ayant une activité d'inhibition sur l'histone désacétylase et produit pharmaceutique comprenant le composé en tant qu'ingrédient actif
CA2671649A1 (en) * 2006-12-06 2008-06-12 Sapporo Medical University Potentiation of cellular immunity using histone deacetylase (hdac) inhibitors
CN101801994A (zh) 2006-12-29 2010-08-11 格洛斯特制药公司 制备Romidepsin
CA2574531C (en) * 2007-01-19 2016-10-25 The University Of British Columbia Hat acetylation promoters and uses of compositions thereof in promoting immunogenicity
KR100909867B1 (ko) * 2007-04-16 2009-07-29 주식회사바이오러넥스 골대사성 질환의 예방 및 치료를 위한 조성물
WO2010006267A2 (en) * 2008-07-11 2010-01-14 University Of Kansas Cyclic tetrapeptides
CA2804795A1 (en) 2010-07-12 2012-01-19 Nicholas Vrolijk Romidepsin solid forms and uses thereof
US8859502B2 (en) 2010-09-13 2014-10-14 Celgene Corporation Therapy for MLL-rearranged leukemia
WO2012074180A1 (ko) * 2010-12-01 2012-06-07 주식회사바이오러넥스 신규한 테트라아자사이클로도데칸-테트라온 유도체 또는 이의 약학적으로 허용 가능한 염, 및 이를 함유하는 암 예방 또는 치료용 약학적 조성물
AU2013202506B2 (en) 2012-09-07 2015-06-18 Celgene Corporation Resistance biomarkers for hdac inhibitors
AU2013202507B9 (en) 2012-11-14 2015-08-13 Celgene Corporation Inhibition of drug resistant cancer cells
NZ630311A (en) 2013-12-27 2016-03-31 Celgene Corp Romidepsin formulations and uses thereof
US11325944B2 (en) 2017-06-16 2022-05-10 University Of Florida Research Foundation, Incorporated Macrocyclic peptides and derivatives thereof with opioid activity
EP3461488A1 (en) 2017-09-27 2019-04-03 Onxeo Combination of a dbait molecule and a hdac inhibitor for treating cancer
EP3461480A1 (en) 2017-09-27 2019-04-03 Onxeo Combination of a dna damage response cell cycle checkpoint inhibitors and belinostat for treating cancer
WO2021148581A1 (en) 2020-01-22 2021-07-29 Onxeo Novel dbait molecule and its use
EP4405680A1 (en) 2021-09-20 2024-07-31 Institut National de la Santé et de la Recherche Médicale (INSERM) Methods for improving the efficacy of hdac inhibitor therapy and predicting the response to treatment with hdac inhibitor
WO2023194441A1 (en) 2022-04-05 2023-10-12 Istituto Nazionale Tumori Irccs - Fondazione G. Pascale Combination of hdac inhibitors and statins for use in the treatment of pancreatic cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0334991A (ja) * 1989-06-30 1991-02-14 Shionogi & Co Ltd 環状テトラペプチドおよびその製造法
CA2231251A1 (en) * 1995-09-20 1997-03-27 Merck & Co., Inc. Histone deacetylase as target for antiprotozoal agents
GB2309696B (en) * 1996-01-31 2000-02-23 Merck & Co Inc Antiprotozoal cyclic tetrapeptides
US6777217B1 (en) * 1996-03-26 2004-08-17 President And Fellows Of Harvard College Histone deacetylases, and uses related thereto

Also Published As

Publication number Publication date
NO20001045L (no) 2000-04-27
WO1999011659A1 (fr) 1999-03-11
NZ503061A (en) 2001-08-31
AU732299B2 (en) 2001-04-12
CA2302451A1 (en) 1999-03-11
US6399568B1 (en) 2002-06-04
AU8888598A (en) 1999-03-22
EP1010705A1 (en) 2000-06-21
EP1010705A4 (en) 2004-09-15
JP3494624B2 (ja) 2004-02-09
KR20010023449A (ko) 2001-03-26

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