NO20000016D0 - Sykliske azapeptider med angiogen virkning - Google Patents

Sykliske azapeptider med angiogen virkning

Info

Publication number
NO20000016D0
NO20000016D0 NO20000016A NO20000016A NO20000016D0 NO 20000016 D0 NO20000016 D0 NO 20000016D0 NO 20000016 A NO20000016 A NO 20000016A NO 20000016 A NO20000016 A NO 20000016A NO 20000016 D0 NO20000016 D0 NO 20000016D0
Authority
NO
Norway
Prior art keywords
angiogenic activity
azapeptides
cyclic
cyclic azapeptides
angiogenic
Prior art date
Application number
NO20000016A
Other languages
English (en)
Norwegian (no)
Other versions
NO20000016L (no
Inventor
Alfred Jonczyk
Simon Goodman
Horst Kessler
Jochen Wermuth
Joerg Schmitt
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of NO20000016L publication Critical patent/NO20000016L/no
Publication of NO20000016D0 publication Critical patent/NO20000016D0/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
NO20000016A 1997-07-04 2000-01-03 Sykliske azapeptider med angiogen virkning NO20000016D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19728524A DE19728524A1 (de) 1997-07-04 1997-07-04 Cyclische Azapeptide
PCT/EP1998/003955 WO1999001472A1 (de) 1997-07-04 1998-06-29 Cyclische azapeptide mit angiogener wirkung

Publications (2)

Publication Number Publication Date
NO20000016L NO20000016L (no) 2000-01-03
NO20000016D0 true NO20000016D0 (no) 2000-01-03

Family

ID=7834596

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20000016A NO20000016D0 (no) 1997-07-04 2000-01-03 Sykliske azapeptider med angiogen virkning

Country Status (20)

Country Link
US (1) US6534478B1 (id)
EP (1) EP1001979B1 (id)
JP (1) JP2002511872A (id)
KR (1) KR20010014267A (id)
CN (1) CN1261895A (id)
AR (1) AR010924A1 (id)
AT (1) ATE297947T1 (id)
AU (1) AU733831B2 (id)
BR (1) BR9810394A (id)
CA (1) CA2297181A1 (id)
DE (2) DE19728524A1 (id)
HU (1) HUP0003357A3 (id)
ID (1) ID23415A (id)
NO (1) NO20000016D0 (id)
PL (1) PL337616A1 (id)
RU (1) RU2188205C2 (id)
SK (1) SK173599A3 (id)
TW (1) TW482768B (id)
WO (1) WO1999001472A1 (id)
ZA (1) ZA985896B (id)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA71608C2 (en) * 1999-03-11 2004-12-15 Merck Patent Gmbh A method for producing the cyclic pentapeptide
AU5566300A (en) * 1999-06-22 2001-01-09 Takeda Chemical Industries Ltd. Acylhydrazine derivatives, process for preparing the same and use thereof
GB0217017D0 (en) * 2002-07-23 2002-08-28 Bioacta Ltd Peptide 2
WO2008033557A2 (en) * 2006-09-15 2008-03-20 Siemens Medical Solutions Usa, Inc. Click chemistry-derived cyclic peptidomimetics as integrin markers
WO2009018175A2 (en) * 2007-07-27 2009-02-05 Siemens Medical Solutions Usa, Inc. Cyclic azapeptides as integrin markers
WO2009134382A2 (en) 2008-04-30 2009-11-05 Siemens Medical Solutions Usa, Inc. Cyclopeptides containing rgd mimetics as imaging markers for integrins
EP2288388B1 (en) 2008-05-30 2016-08-31 Siemens Medical Solutions USA, Inc. Achievement of high therapeutic index through molecular imaging guided targeted drug treatment
CA2665302A1 (en) * 2009-05-01 2010-11-01 Universite De Montreal Cd36 modulation and uses thereof
CN101906144B (zh) * 2009-06-03 2013-06-19 首都医科大学 一根Arg-Gly-Asp-Val链通过Asp与两根脂肪醇链的偶联物、它们的合成及在医学中的应用
KR101335203B1 (ko) * 2010-03-26 2013-11-29 숙명여자대학교산학협력단 혈관신생촉진용 펩타이드 및 이의 용도

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993024520A1 (en) * 1992-06-04 1993-12-09 Merrell Dow Pharmaceuticals Inc. Conformationally restrained peptide analogs as antiplatelet agents
UA43823C2 (uk) * 1992-07-06 2002-01-15 Мерк Патент Геселлшафт Міт Бесшренктер Хафтунг ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ ДЛЯ ІНГІБУВАННЯ ІНТЕГРИН <font face="Symbol">a</font><sub>V</sub><font face="Symbol">b</font><sub>3</sub>-ОПОСЕРЕДКОВАНОЇ КЛІТИННОЇ АДГЕЗІЇ КЛІТИН ССАВЦІВ, СПОСІБ ЛІКУВАННЯ ТА ПРОФІЛАКТИКИ ЗАХВОРЮВАННЯ, АСОЦІЙОВАНОГО З ПОРУШЕННЯМ АДГЕЗІЇ КЛІТИН, СПОСІБ БЛОКУВАННЯ ЗВ'ЯЗУВАННЯ ФІБРИНОГЕНОМ ІНТЕГРИНУ, КОМПОЗИЦІЯ ДЛЯ ЗАГОЄННЯ РАН
AU1975695A (en) * 1994-03-04 1995-09-18 Du Pont Merck Pharmaceutical Company, The Novel carbocyclic compounds which inhibit platelet aggregation by interaction with the gpiib/iiia receptor complex
US5858972A (en) * 1996-01-11 1999-01-12 La Jolla Cancer Research Foundation Antithrombotic agents and methods of use
ZA978758B (en) * 1996-10-02 1999-03-30 Du Pont Merck Pharma Technetium-99m-labeled chelator incorporated cyclic peptides that bind to the GPIIb/IIIa receptor as imaging agents
DE19653036A1 (de) * 1996-12-19 1998-06-25 Merck Patent Gmbh Cyclopeptidderivate

Also Published As

Publication number Publication date
WO1999001472A1 (de) 1999-01-14
ATE297947T1 (de) 2005-07-15
CA2297181A1 (en) 1999-01-14
PL337616A1 (en) 2000-08-28
NO20000016L (no) 2000-01-03
EP1001979A1 (de) 2000-05-24
AU8541198A (en) 1999-01-25
JP2002511872A (ja) 2002-04-16
AU733831B2 (en) 2001-05-24
HUP0003357A2 (hu) 2001-02-28
BR9810394A (pt) 2000-09-05
AR010924A1 (es) 2000-07-12
DE59812870D1 (de) 2005-07-21
EP1001979B1 (de) 2005-06-15
SK173599A3 (en) 2000-06-12
DE19728524A1 (de) 1999-01-07
TW482768B (en) 2002-04-11
KR20010014267A (ko) 2001-02-26
CN1261895A (zh) 2000-08-02
HUP0003357A3 (en) 2001-12-28
ID23415A (id) 2000-04-20
US6534478B1 (en) 2003-03-18
ZA985896B (en) 1999-06-14
RU2188205C2 (ru) 2002-08-27

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