ID23415A - Azapeptida siklik dengan efek angiogenik - Google Patents

Azapeptida siklik dengan efek angiogenik

Info

Publication number
ID23415A
ID23415A IDW991514A ID991514A ID23415A ID 23415 A ID23415 A ID 23415A ID W991514 A IDW991514 A ID W991514A ID 991514 A ID991514 A ID 991514A ID 23415 A ID23415 A ID 23415A
Authority
ID
Indonesia
Prior art keywords
azapeptides
cycle
angiogenic effects
angiogenic
effects
Prior art date
Application number
IDW991514A
Other languages
English (en)
Inventor
Alfred Jonczyk
Simon Goodman
Horst Kessler
Jochen Wermuth
Jorg Schmitt
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of ID23415A publication Critical patent/ID23415A/id

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IDW991514A 1997-07-04 1998-06-29 Azapeptida siklik dengan efek angiogenik ID23415A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19728524A DE19728524A1 (de) 1997-07-04 1997-07-04 Cyclische Azapeptide

Publications (1)

Publication Number Publication Date
ID23415A true ID23415A (id) 2000-04-20

Family

ID=7834596

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW991514A ID23415A (id) 1997-07-04 1998-06-29 Azapeptida siklik dengan efek angiogenik

Country Status (20)

Country Link
US (1) US6534478B1 (id)
EP (1) EP1001979B1 (id)
JP (1) JP2002511872A (id)
KR (1) KR20010014267A (id)
CN (1) CN1261895A (id)
AR (1) AR010924A1 (id)
AT (1) ATE297947T1 (id)
AU (1) AU733831B2 (id)
BR (1) BR9810394A (id)
CA (1) CA2297181A1 (id)
DE (2) DE19728524A1 (id)
HU (1) HUP0003357A3 (id)
ID (1) ID23415A (id)
NO (1) NO20000016L (id)
PL (1) PL337616A1 (id)
RU (1) RU2188205C2 (id)
SK (1) SK173599A3 (id)
TW (1) TW482768B (id)
WO (1) WO1999001472A1 (id)
ZA (1) ZA985896B (id)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA71608C2 (en) * 1999-03-11 2004-12-15 Merck Patent Gmbh A method for producing the cyclic pentapeptide
US6723722B1 (en) 1999-06-22 2004-04-20 Takeda Chemical Industries, Ltd. Acylhydrazine derivatives, their production and use
GB0217017D0 (en) * 2002-07-23 2002-08-28 Bioacta Ltd Peptide 2
WO2008033557A2 (en) * 2006-09-15 2008-03-20 Siemens Medical Solutions Usa, Inc. Click chemistry-derived cyclic peptidomimetics as integrin markers
EP2182974B1 (en) 2007-07-27 2015-08-26 Siemens Medical Solutions USA, Inc. Cyclic azapeptides as integrin markers
US8133472B2 (en) 2008-04-30 2012-03-13 Siemens Medical Solutions Usa, Inc. Cyclopeptides containing RGD mimetics as imaging markers for integrins
WO2009148554A1 (en) 2008-05-30 2009-12-10 Siemens Medical Solutions Usa, Inc. Achievement of high therapeutic index through molecular imaging guided targeted drug treatment
CA2665302A1 (en) * 2009-05-01 2010-11-01 Universite De Montreal Cd36 modulation and uses thereof
CN101906144B (zh) * 2009-06-03 2013-06-19 首都医科大学 一根Arg-Gly-Asp-Val链通过Asp与两根脂肪醇链的偶联物、它们的合成及在医学中的应用
KR101335203B1 (ko) * 2010-03-26 2013-11-29 숙명여자대학교산학협력단 혈관신생촉진용 펩타이드 및 이의 용도

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3398747B2 (ja) * 1992-06-04 2003-04-21 メレルダウファーマスーティカルズ インコーポレイテッド 抗血小板剤としての立体配位が制限されたペプチド類似体
UA43823C2 (uk) * 1992-07-06 2002-01-15 Мерк Патент Геселлшафт Міт Бесшренктер Хафтунг ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ ДЛЯ ІНГІБУВАННЯ ІНТЕГРИН <font face="Symbol">a</font><sub>V</sub><font face="Symbol">b</font><sub>3</sub>-ОПОСЕРЕДКОВАНОЇ КЛІТИННОЇ АДГЕЗІЇ КЛІТИН ССАВЦІВ, СПОСІБ ЛІКУВАННЯ ТА ПРОФІЛАКТИКИ ЗАХВОРЮВАННЯ, АСОЦІЙОВАНОГО З ПОРУШЕННЯМ АДГЕЗІЇ КЛІТИН, СПОСІБ БЛОКУВАННЯ ЗВ'ЯЗУВАННЯ ФІБРИНОГЕНОМ ІНТЕГРИНУ, КОМПОЗИЦІЯ ДЛЯ ЗАГОЄННЯ РАН
WO1995023811A1 (en) * 1994-03-04 1995-09-08 The Du Pont Merck Pharmaceutical Company Novel carbocyclic compounds which inhibit platelet aggregation by interaction with the gpiib/iiia receptor complex
US5858972A (en) * 1996-01-11 1999-01-12 La Jolla Cancer Research Foundation Antithrombotic agents and methods of use
ZA978758B (en) * 1996-10-02 1999-03-30 Du Pont Merck Pharma Technetium-99m-labeled chelator incorporated cyclic peptides that bind to the GPIIb/IIIa receptor as imaging agents
DE19653036A1 (de) * 1996-12-19 1998-06-25 Merck Patent Gmbh Cyclopeptidderivate

Also Published As

Publication number Publication date
HUP0003357A3 (en) 2001-12-28
AU8541198A (en) 1999-01-25
KR20010014267A (ko) 2001-02-26
BR9810394A (pt) 2000-09-05
EP1001979B1 (de) 2005-06-15
NO20000016D0 (no) 2000-01-03
AU733831B2 (en) 2001-05-24
ATE297947T1 (de) 2005-07-15
JP2002511872A (ja) 2002-04-16
DE59812870D1 (de) 2005-07-21
DE19728524A1 (de) 1999-01-07
AR010924A1 (es) 2000-07-12
CN1261895A (zh) 2000-08-02
SK173599A3 (en) 2000-06-12
US6534478B1 (en) 2003-03-18
TW482768B (en) 2002-04-11
PL337616A1 (en) 2000-08-28
CA2297181A1 (en) 1999-01-14
HUP0003357A2 (hu) 2001-02-28
ZA985896B (en) 1999-06-14
RU2188205C2 (ru) 2002-08-27
EP1001979A1 (de) 2000-05-24
WO1999001472A1 (de) 1999-01-14
NO20000016L (no) 2000-01-03

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