AU1975695A - Novel carbocyclic compounds which inhibit platelet aggregation by interaction with the gpiib/iiia receptor complex - Google Patents

Novel carbocyclic compounds which inhibit platelet aggregation by interaction with the gpiib/iiia receptor complex

Info

Publication number
AU1975695A
AU1975695A AU19756/95A AU1975695A AU1975695A AU 1975695 A AU1975695 A AU 1975695A AU 19756/95 A AU19756/95 A AU 19756/95A AU 1975695 A AU1975695 A AU 1975695A AU 1975695 A AU1975695 A AU 1975695A
Authority
AU
Australia
Prior art keywords
gpiib
interaction
platelet aggregation
receptor complex
inhibit platelet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU19756/95A
Inventor
William Frank Degrado
Ronald Herman Hoess
Sharon Anne Jackson
Shaker Ahmed Mousa
Karyn Thompson O'Neil
Arlene Lynnae Rockwell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Pharma Co
Original Assignee
DuPont Merck Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DuPont Merck Pharmaceutical Co filed Critical DuPont Merck Pharmaceutical Co
Publication of AU1975695A publication Critical patent/AU1975695A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/75—Fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU19756/95A 1994-03-04 1995-03-01 Novel carbocyclic compounds which inhibit platelet aggregation by interaction with the gpiib/iiia receptor complex Abandoned AU1975695A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20543394A 1994-03-04 1994-03-04
US205433 1994-03-04
PCT/US1995/002572 WO1995023811A1 (en) 1994-03-04 1995-03-01 Novel carbocyclic compounds which inhibit platelet aggregation by interaction with the gpiib/iiia receptor complex

Publications (1)

Publication Number Publication Date
AU1975695A true AU1975695A (en) 1995-09-18

Family

ID=22762167

Family Applications (1)

Application Number Title Priority Date Filing Date
AU19756/95A Abandoned AU1975695A (en) 1994-03-04 1995-03-01 Novel carbocyclic compounds which inhibit platelet aggregation by interaction with the gpiib/iiia receptor complex

Country Status (2)

Country Link
AU (1) AU1975695A (en)
WO (1) WO1995023811A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA978758B (en) * 1996-10-02 1999-03-30 Du Pont Merck Pharma Technetium-99m-labeled chelator incorporated cyclic peptides that bind to the GPIIb/IIIa receptor as imaging agents
DE19728524A1 (en) 1997-07-04 1999-01-07 Merck Patent Gmbh Cyclic azapeptides

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5384309A (en) * 1989-07-17 1995-01-24 Genentech, Inc. Cyclized peptides and their use as platelet aggregation inhibitors
IL103252A (en) * 1991-09-30 1997-03-18 Du Pont Merck Pharma CYCLIC COMPOUNDS USEFUL AS INHIBITORS OF PLATELET GLYCOPROTEIN IIb/IIIa AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Also Published As

Publication number Publication date
WO1995023811A1 (en) 1995-09-08

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