NO180619C - Pyridazindion-forbindelser - Google Patents
Pyridazindion-forbindelserInfo
- Publication number
- NO180619C NO180619C NO921841A NO921841A NO180619C NO 180619 C NO180619 C NO 180619C NO 921841 A NO921841 A NO 921841A NO 921841 A NO921841 A NO 921841A NO 180619 C NO180619 C NO 180619C
- Authority
- NO
- Norway
- Prior art keywords
- alkyl
- opt
- substd
- phenyl
- ring
- Prior art date
Links
- MYKHANQTTIRZJK-UHFFFAOYSA-N pyridazine-3,4-dione Chemical class O=C1C=CN=NC1=O MYKHANQTTIRZJK-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 11
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 5
- 125000001475 halogen functional group Chemical group 0.000 abstract 2
- 125000004076 pyridyl group Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 208000012902 Nervous system disease Diseases 0.000 abstract 1
- 208000025966 Neurological disease Diseases 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 238000005804 alkylation reaction Methods 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 125000000717 hydrazino group Chemical group [H]N([*])N([H])[H] 0.000 abstract 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
- 125000005010 perfluoroalkyl group Chemical group 0.000 abstract 1
- BOYBQQBDCOIBIR-UHFFFAOYSA-N pyrido[2,3-f]cinnoline Chemical compound N1=CC=C2C3=NC=CC=C3C=CC2=N1 BOYBQQBDCOIBIR-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB919109973A GB9109973D0 (en) | 1991-05-09 | 1991-05-09 | Therapeutic compositions |
| GB929202991A GB9202991D0 (en) | 1992-02-13 | 1992-02-13 | Compounds |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO921841D0 NO921841D0 (no) | 1992-05-08 |
| NO921841L NO921841L (no) | 1992-11-10 |
| NO180619B NO180619B (no) | 1997-02-10 |
| NO180619C true NO180619C (no) | 1997-05-21 |
Family
ID=26298868
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO921841A NO180619C (no) | 1991-05-09 | 1992-05-08 | Pyridazindion-forbindelser |
Country Status (21)
| Country | Link |
|---|---|
| US (4) | US5604227A (de) |
| EP (1) | EP0516297B1 (de) |
| JP (1) | JP3279633B2 (de) |
| KR (1) | KR100231095B1 (de) |
| AT (1) | ATE144707T1 (de) |
| AU (1) | AU642086B2 (de) |
| CA (1) | CA2067537A1 (de) |
| CZ (1) | CZ286814B6 (de) |
| DE (1) | DE69214881T2 (de) |
| DK (1) | DK0516297T3 (de) |
| ES (1) | ES2093782T3 (de) |
| FI (1) | FI102754B (de) |
| GB (1) | GB9208511D0 (de) |
| GR (1) | GR3021512T3 (de) |
| HU (2) | HUT61302A (de) |
| IE (1) | IE921294A1 (de) |
| IL (1) | IL101711A0 (de) |
| MY (1) | MY108482A (de) |
| NO (1) | NO180619C (de) |
| NZ (1) | NZ242540A (de) |
| SK (1) | SK280336B6 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2676053B1 (fr) * | 1991-05-03 | 1993-08-27 | Sanofi Elf | Nouveaux composes dialkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant. |
| GB9208511D0 (en) * | 1991-05-09 | 1992-06-03 | Ici Plc | Compounds |
| CA2115792C (en) | 1993-03-05 | 2005-11-01 | David J. Mayer | Method for the treatment of pain |
| US5834479A (en) * | 1993-03-05 | 1998-11-10 | Mayer; David J. | Method and composition for alleviating pain |
| IL111266A (en) * | 1993-10-22 | 2002-03-10 | Zeneca Ltd | 2-HETEROARYL OR 2-ARYLPYRIDAZINO [4,5-b] QUINOLINE - 1, 10 - DIONES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| GB9411955D0 (en) * | 1994-06-15 | 1994-08-03 | Merck Sharp & Dohme | Therapeutic agents |
| GB9422894D0 (en) * | 1994-11-12 | 1995-01-04 | Zeneca Ltd | Pyridazino quinoline compounds |
| US6214826B1 (en) | 1994-11-12 | 2001-04-10 | Zeneca Limited | Pyridazino quinoline compounds |
| GB9507318D0 (en) * | 1995-04-07 | 1995-05-31 | Zeneca Ltd | Alpha substituted pyridazino quinoline compounds |
| US5776935A (en) | 1996-07-25 | 1998-07-07 | Merz & Co. Gmbh & Co. | Pyrido-phtalazin diones and their use against neurological disorders associated with excitotoxicity and malfunctioning of glutamatergic neurotransmission |
| US6861442B1 (en) * | 1998-12-30 | 2005-03-01 | Sugen, Inc. | PYK2 and inflammation |
| AU4397200A (en) * | 1999-03-31 | 2000-10-16 | Basf Aktiengesellschaft | Pyridine-2,3-dicarboxylic acid diamides |
| US6417394B2 (en) * | 2000-04-05 | 2002-07-09 | Bristol Myers Squibb Pharma Company | Specific salt forms of triphenylethylene derivatives as selective estrogen receptor modulators |
| KR100965861B1 (ko) | 2002-10-24 | 2010-06-24 | 삼성전자주식회사 | 이동통신 시스템에서 복합 재전송 제어 장치 |
| GB0525068D0 (en) * | 2005-12-08 | 2006-01-18 | Novartis Ag | Organic compounds |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9208511D0 (en) * | 1991-05-09 | 1992-06-03 | Ici Plc | Compounds |
-
1992
- 1992-04-16 GB GB929208511A patent/GB9208511D0/en active Pending
- 1992-04-22 IE IE129492A patent/IE921294A1/en not_active IP Right Cessation
- 1992-04-28 AU AU15213/92A patent/AU642086B2/en not_active Ceased
- 1992-04-28 MY MYPI92000780A patent/MY108482A/en unknown
- 1992-04-28 IL IL101711A patent/IL101711A0/xx unknown
- 1992-04-29 NZ NZ242540A patent/NZ242540A/en unknown
- 1992-04-29 CA CA002067537A patent/CA2067537A1/en not_active Abandoned
- 1992-05-04 HU HU9201486A patent/HUT61302A/hu unknown
- 1992-05-06 ES ES92304084T patent/ES2093782T3/es not_active Expired - Lifetime
- 1992-05-06 DE DE69214881T patent/DE69214881T2/de not_active Expired - Fee Related
- 1992-05-06 AT AT92304084T patent/ATE144707T1/de not_active IP Right Cessation
- 1992-05-06 EP EP92304084A patent/EP0516297B1/de not_active Expired - Lifetime
- 1992-05-06 DK DK92304084.4T patent/DK0516297T3/da active
- 1992-05-07 CZ CS19921396A patent/CZ286814B6/cs not_active IP Right Cessation
- 1992-05-07 SK SK1396-92A patent/SK280336B6/sk unknown
- 1992-05-08 NO NO921841A patent/NO180619C/no not_active IP Right Cessation
- 1992-05-08 KR KR1019920007938A patent/KR100231095B1/ko not_active IP Right Cessation
- 1992-05-08 FI FI922099A patent/FI102754B/fi active
- 1992-05-11 JP JP11728592A patent/JP3279633B2/ja not_active Expired - Fee Related
-
1995
- 1995-04-13 US US08/421,133 patent/US5604227A/en not_active Expired - Lifetime
- 1995-04-24 US US08/427,469 patent/US5599814A/en not_active Expired - Lifetime
- 1995-06-23 HU HU95P/P00416P patent/HU211149A9/hu unknown
-
1996
- 1996-08-05 US US08/689,259 patent/US5733910A/en not_active Expired - Lifetime
- 1996-08-15 US US08/700,654 patent/US5739133A/en not_active Expired - Fee Related
- 1996-10-31 GR GR960402628T patent/GR3021512T3/el unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |
Free format text: LAPSED IN NOVEMBER 2003 |