NO178968C - Analogifremgangsmåte for fremstilling av terapeutisk aktive aminopyrimidin-karboksamidderivater - Google Patents

Analogifremgangsmåte for fremstilling av terapeutisk aktive aminopyrimidin-karboksamidderivater

Info

Publication number
NO178968C
NO178968C NO905591A NO905591A NO178968C NO 178968 C NO178968 C NO 178968C NO 905591 A NO905591 A NO 905591A NO 905591 A NO905591 A NO 905591A NO 178968 C NO178968 C NO 178968C
Authority
NO
Norway
Prior art keywords
aminopyrimidine
therapeutically active
carboxamide derivatives
analogous process
preparing therapeutically
Prior art date
Application number
NO905591A
Other languages
English (en)
Other versions
NO178968B (no
NO905591L (no
NO905591D0 (no
Inventor
Pascal George
Philippe Manoury
Jacques Froissant
Jean-Pierre Merly
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of NO905591D0 publication Critical patent/NO905591D0/no
Publication of NO905591L publication Critical patent/NO905591L/no
Publication of NO178968B publication Critical patent/NO178968B/no
Publication of NO178968C publication Critical patent/NO178968C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
NO905591A 1989-12-28 1990-12-27 Analogifremgangsmåte for fremstilling av terapeutisk aktive aminopyrimidin-karboksamidderivater NO178968C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8917304A FR2656609B1 (fr) 1989-12-28 1989-12-28 Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique.

Publications (4)

Publication Number Publication Date
NO905591D0 NO905591D0 (no) 1990-12-27
NO905591L NO905591L (no) 1991-07-01
NO178968B NO178968B (no) 1996-04-01
NO178968C true NO178968C (no) 1996-07-10

Family

ID=9389050

Family Applications (1)

Application Number Title Priority Date Filing Date
NO905591A NO178968C (no) 1989-12-28 1990-12-27 Analogifremgangsmåte for fremstilling av terapeutisk aktive aminopyrimidin-karboksamidderivater

Country Status (22)

Country Link
US (1) US5164397A (no)
EP (1) EP0435749B1 (no)
JP (1) JP2515434B2 (no)
KR (1) KR910011841A (no)
AT (1) ATE132859T1 (no)
AU (1) AU630777B2 (no)
CA (1) CA2033303A1 (no)
CS (1) CS405291A3 (no)
DE (1) DE69024778T2 (no)
DK (1) DK0435749T3 (no)
ES (1) ES2084015T3 (no)
FI (1) FI94953C (no)
FR (1) FR2656609B1 (no)
GR (1) GR3019508T3 (no)
HU (1) HU207515B (no)
IE (1) IE72954B1 (no)
IL (1) IL96815A (no)
MX (1) MX172953B (no)
NO (1) NO178968C (no)
NZ (1) NZ236605A (no)
PT (1) PT96381B (no)
ZA (1) ZA9010412B (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2667317B1 (fr) * 1990-10-02 1992-12-04 Synthelabo Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique.
FR2678272B1 (fr) * 1991-06-27 1994-01-14 Synthelabo Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique.
FR2678271B1 (fr) * 1991-06-27 1995-01-13 Synthelabo Derives de pyrimidine-4-carboxamide, leur preparation et leur application en therapeutique.
CZ279305B6 (cs) * 1992-01-24 1995-04-12 Lonza A.G. Kyseliny 2-halogen pyrimidin-4-karboxylové, způsob jejich přípravy a jejich použití pro přípravu derivátů substituovaných pyrimidinů-4-karboxylový ch kyselin
US5474994A (en) * 1992-05-26 1995-12-12 Recordati S.A., Chemical And Pharmaceutical Company Bicyclic heterocyclic derivatives having α1 -adrenergic and 5HT1A
IT1254469B (it) * 1992-02-25 1995-09-25 Recordati Chem Pharm Derivati benzopiranici e benzotiopiranici
FR2699171B1 (fr) * 1992-12-14 1995-02-03 Synthelabo Dérivés de 2-amino-N[[[4-aminocarbonyl) pyrimidin-2-yl]amino]alkyl]pyrimidine-4-carboxamide, leur préparation et leur application en thérapeutique.
FR2693195B1 (fr) * 1992-07-03 1994-09-23 Synthelabo Dérivés de 2-amino-N-[[[(4-aminocarbonyl)pyrimidin-2-yl]amino]alkyl] pyrimidine-4-carboxamide, leur préparation et leur application en thérapeutique.
ES2073951T3 (es) * 1992-07-03 1995-08-16 Synthelabo Derivados de 2-amino-n-(((4-(aminocarbonil)pirimidin-2-il)amino)alquil)pirimidina-4-carboxamida, su preparacion y su aplicacion en terapeutica.
FR2703355B1 (fr) * 1993-03-29 1995-05-05 Synthelabo Dérivés de 2-aminopyrimidine-4-carboxamide, leur préparation et leur application en thérapeutique.
FR2705344B1 (fr) * 1993-05-17 1995-06-30 Synthelabo Dérivés de 2-aminopyrazine-5-carboxamide, leur préparation et leur application en thérapeutique.
FR2724383B1 (fr) * 1994-09-13 1996-10-18 Synthelabo Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique
US5688795A (en) * 1994-11-08 1997-11-18 Syntex (U.S.A.) Inc. 3-(4-phenylpiperazin-1-yl)propyl-amino, thio and oxy!-pyridine, pyrimidine and benzene derivatives as α1 -adrenoceptor antagonists
FR2744722B1 (fr) * 1996-02-14 1998-03-13 Synthelabo Devires de 2-((3-(piperazin-1-yl)propyl)amino)pyrimidine-4- carboxamide et leur application en therapeutique
TW593290B (en) 1996-05-10 2004-06-21 Janssen Pharmaceutica Nv Alkylaminobenzothiazole and -benzoxazole derivatives
ITMI20010164A1 (it) * 2001-01-30 2002-07-30 Recordati Chem Pharm Alfa 1 antagonisti selettivi a + d
AR078793A1 (es) 2009-10-27 2011-12-07 Orion Corp Derivados de carboxamidas no esteroidales y acil hidrazona moduladores de receptores androgenicos de tejido selectivo (sarm), composiciones farmaceuticas que los contienen y uso de los mismos en el tratamiento del cancer de prostata entre otros
WO2013169964A1 (en) 2012-05-09 2013-11-14 Sunovion Pharmaceuticals Inc. Heteroaryl compounds and methods of use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE787126A (fr) * 1971-08-04 1973-02-05 Byk Gulden Lomberg Chem Fab Pyrimidines substituees, procedes de preparation de ces composes et medicaments contenant lesdits composes
DE2143730A1 (de) * 1971-09-01 1973-03-08 Byk Gulden Lomberg Chem Fab Substituierte pyridine, verfahren zu deren herstellung und sie enthaltende arzneimittel

Also Published As

Publication number Publication date
US5164397A (en) 1992-11-17
NZ236605A (en) 1992-08-26
EP0435749A1 (fr) 1991-07-03
MX172953B (es) 1994-01-25
CA2033303A1 (en) 1991-06-29
KR910011841A (ko) 1991-08-07
IL96815A (en) 1996-06-18
IE72954B1 (en) 1997-05-07
FI94953C (fi) 1995-11-27
FI906408A0 (fi) 1990-12-27
ATE132859T1 (de) 1996-01-15
PT96381B (pt) 1998-06-30
DK0435749T3 (da) 1996-05-20
AU630777B2 (en) 1992-11-05
PT96381A (pt) 1991-10-15
EP0435749B1 (fr) 1996-01-10
HUT56092A (en) 1991-07-29
JP2515434B2 (ja) 1996-07-10
NO178968B (no) 1996-04-01
NO905591L (no) 1991-07-01
FI906408A (fi) 1991-06-29
IE904719A1 (en) 1991-07-17
CS405291A3 (en) 1992-04-15
FR2656609A1 (fr) 1991-07-05
ES2084015T3 (es) 1996-05-01
IL96815A0 (en) 1991-09-16
DE69024778T2 (de) 1996-09-19
AU6845190A (en) 1991-07-04
FI94953B (fi) 1995-08-15
JPH04139173A (ja) 1992-05-13
ZA9010412B (en) 1991-10-30
FR2656609B1 (fr) 1992-03-27
HU207515B (en) 1993-04-28
GR3019508T3 (en) 1996-07-31
NO905591D0 (no) 1990-12-27
DE69024778D1 (de) 1996-02-22

Similar Documents

Publication Publication Date Title
NO178968C (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive aminopyrimidin-karboksamidderivater
HUP0101999A2 (hu) 4-Hidroxi-kinolin-3-karboxamid- és -hidrazid-származékok, ezeket tartalmazó gyógyászati készítmények, valamint e vegyületek alkalmazása
ATE143815T1 (de) Polymerbeschichtung
NO930498L (no) Fremgangsmaate for fremstilling av benzimidazolderivater
FI98729B (fi) Menetelmä farmaseuttisesti vaikuttavan puriinijohdannaisen valmistamiseksi
MX9204029A (es) Procedimiento de preparacion de un derivado de la bacatina iii y de la 10-desacetil bacatina iii
FI922983A0 (fi) Pyrimidin-4-karboxamidderivat, framstaellning av dessa och terapeutisk anvaendning av dessa.
ES2053748T3 (es) Oxazoles y tiazoles para el tratamiento de la demencia senil.
FI101376B1 (fi) Menetelmä 3-bentsyyliamino-2-fenyylipiperidiinijohdannaisten valmistamiseksi
NO891949D0 (no) Fremgangsmaate for fremstilling av terapeutisk aktive pyrimidindionforbindelser.
ES2108595A1 (es) Derivados de la 3(2h)-piridacinona y procedimiento para su preparacion.
MX9804828A (es) Benzotiazolona etanaminas biologicamente activas.
ES2082882T3 (es) Procedimiento para la fabricacion de derivados de acidos-3-amino-2-(het)aroil-acrilicos.
DK0628042T3 (da) Serotoninerge ergolinderivater
FI913713A0 (fi) Nya bicykliska aminosubstituerade foereningar.
ATE63309T1 (de) 2,3-dihydro-2-oxo-3-benzofuranylessigs|urederivate und diese enthaltende arzneimittel.
PT90262A (pt) Processo para a preparacao de novos derivados trienicos com estrutura cromenica
AU1621392A (en) New 1-amidooctahydropyrido(2,1-c)(1,4)oxazine compounds, processes for preparing these and pharmaceutical compositions containing them
FI934016A (fi) Foerfarande foer framstaellning av terapeutiskt aktiva kinolin- eller naftyridinkarboxylsyraderivat som innehaoller en spirosubstituent
TW349945B (en) Substituted benzenedicarboxylic acid diguanides, process for their preparation, their use as a medicament or diagnostic
YU49004B (sh) LANOSTA-7,9-DIEN-3Гџ, 32-DIOL I POSTUPAK ZA NJEGOVO DOBIJANJE