NO170330C - Fremgangsmaate for fremstilling av vesentlig optisk rent monohydrat av s-(-)-propyl-2',6'-pipekoloksylididhydroklorid - Google Patents

Fremgangsmaate for fremstilling av vesentlig optisk rent monohydrat av s-(-)-propyl-2',6'-pipekoloksylididhydroklorid

Info

Publication number
NO170330C
NO170330C NO864858A NO864858A NO170330C NO 170330 C NO170330 C NO 170330C NO 864858 A NO864858 A NO 864858A NO 864858 A NO864858 A NO 864858A NO 170330 C NO170330 C NO 170330C
Authority
NO
Norway
Prior art keywords
pipecoloxylide
hydrochloride
propyl
procedure
preparation
Prior art date
Application number
NO864858A
Other languages
English (en)
Norwegian (no)
Other versions
NO864858L (no
NO864858D0 (no
NO170330B (no
Inventor
Rune Verner Sandberg
Original Assignee
Astra Laekemedel Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20363001&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO170330(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astra Laekemedel Ab filed Critical Astra Laekemedel Ab
Publication of NO864858D0 publication Critical patent/NO864858D0/no
Publication of NO864858L publication Critical patent/NO864858L/no
Publication of NO170330B publication Critical patent/NO170330B/no
Publication of NO170330C publication Critical patent/NO170330C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO864858A 1986-01-03 1986-12-03 Fremgangsmaate for fremstilling av vesentlig optisk rent monohydrat av s-(-)-propyl-2',6'-pipekoloksylididhydroklorid NO170330C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8600017A SE451840B (sv) 1986-01-03 1986-01-03 Optiskt rent monohydrat av s-(-)-1-propyl-2',6'-pipekoloxylididhydroklorid, sett att framstella denna och farmaceutiska beredningar for lokalbedovning

Publications (4)

Publication Number Publication Date
NO864858D0 NO864858D0 (no) 1986-12-03
NO864858L NO864858L (no) 1987-07-06
NO170330B NO170330B (no) 1992-06-29
NO170330C true NO170330C (no) 1992-10-07

Family

ID=20363001

Family Applications (2)

Application Number Title Priority Date Filing Date
NO864858A NO170330C (no) 1986-01-03 1986-12-03 Fremgangsmaate for fremstilling av vesentlig optisk rent monohydrat av s-(-)-propyl-2',6'-pipekoloksylididhydroklorid
NO1997009C NO1997009I1 (no) 1986-01-03 1997-07-31 Ropivacain

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO1997009C NO1997009I1 (no) 1986-01-03 1997-07-31 Ropivacain

Country Status (29)

Country Link
US (1) US4870086A (es)
EP (1) EP0239710B1 (es)
JP (1) JPH07598B2 (es)
KR (1) KR940008302B1 (es)
AR (1) AR242561A1 (es)
AT (1) ATE56956T1 (es)
AU (1) AU592392B2 (es)
BG (1) BG62066B2 (es)
CA (1) CA1276154C (es)
CY (1) CY1680A (es)
DE (1) DE3674582D1 (es)
DK (1) DK171378B1 (es)
EG (1) EG17867A (es)
ES (1) ES2036179T3 (es)
FI (1) FI83075C (es)
GR (1) GR3002516T3 (es)
HK (1) HK5493A (es)
IE (1) IE59061B1 (es)
LU (1) LU88843I2 (es)
LV (1) LV5765B4 (es)
MY (1) MY101132A (es)
NL (1) NL960005I2 (es)
NO (2) NO170330C (es)
NZ (1) NZ218615A (es)
PH (1) PH22924A (es)
PT (1) PT84041B (es)
SE (1) SE451840B (es)
SG (1) SG117292G (es)
ZA (1) ZA868600B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ238424A (en) * 1990-06-07 1993-12-23 Wellcome Found 3,5-substituted indole derivatives; medicaments and preparatory processes.
ES2082703B1 (es) * 1993-11-04 1996-12-16 Inst Investigacion Desarrollo Nuevos derivados de ciclopropilo, procedimientos para su preparacion y aplicaciones.
US5834490A (en) * 1993-11-04 1998-11-10 Instituto De Investigacion Y Desarrolo Quimico Biologico, S.A. Cyclopropyl derivatives, preparation method there-of and applications
CN1104416C (zh) * 1994-09-23 2003-04-02 达尔文发现有限公司 制左旋布比卡因及类似物中所用的外消旋及不对称转变方法
SE9501808D0 (sv) * 1995-05-16 1995-05-16 Astra Ab New process
US7799337B2 (en) 1997-07-21 2010-09-21 Levin Bruce H Method for directed intranasal administration of a composition
SE9800139D0 (sv) 1998-01-21 1998-01-21 Astra Ab New use
BRPI0104491B8 (pt) * 2001-10-10 2021-05-25 Cristalia Produtos Quim Farmaceuticos Ltda n-(2,6-dimetilfenil)-1-propil-2-piperidinocarboxamida; processo de obtenção dos enantiômeros; mistura não racêmica dos anantiômeros e seu processo de obtenção e composição farmacêutica.
US20060270708A1 (en) * 2005-05-25 2006-11-30 Navinta Llc Novel process for preparation of isotonic aqueous injection of ropivacaine
US7683175B2 (en) * 2005-06-06 2010-03-23 Navinta, Llc Process of making optically pure L-pipecolic acid and process of making anesthetics and intermediates therefrom
WO2007123405A1 (en) * 2006-04-25 2007-11-01 Dishman Pharmaceuticals And Chemicals Ltd. Ropivacaine hydrochloride anhydrate and the preparation thereof
ATE555093T1 (de) * 2008-01-15 2012-05-15 Pharmathen Sa Verfahren zur herstellung einer (s)-1-alkyl-2i,6i-pipecoloxylididverbindung
US8473062B2 (en) 2008-05-01 2013-06-25 Autonomic Technologies, Inc. Method and device for the treatment of headache
US8412336B2 (en) 2008-12-29 2013-04-02 Autonomic Technologies, Inc. Integrated delivery and visualization tool for a neuromodulation system
US9320908B2 (en) 2009-01-15 2016-04-26 Autonomic Technologies, Inc. Approval per use implanted neurostimulator
US8494641B2 (en) 2009-04-22 2013-07-23 Autonomic Technologies, Inc. Implantable neurostimulator with integral hermetic electronic enclosure, circuit substrate, monolithic feed-through, lead assembly and anchoring mechanism
CN102093284B (zh) * 2010-12-29 2013-05-08 宜昌人福药业有限责任公司 富集哌啶-2-甲酰苯胺类旋光化合物的方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2248018A (en) * 1939-03-30 1941-07-01 Winthrop Chem Co Inc 4-aryl-piperidine-ketones and a process of preparing them
GB775749A (en) * 1955-04-06 1957-05-29 Bofors Ab Method of preparing amides of n-alkyl piperidine monocarboxylic acid and n-alkyl pyrrolidine -a-monocarboxylic acid
US2799679A (en) * 1955-04-28 1957-07-16 Bofors Ab Process of preparing amides of heterocyclic carboxylic acids
GB775750A (en) * 1955-04-28 1957-05-29 Bofors Ab Method of preparing amides of n-alkyl piperidine mono-carboxylic acid and n-alkyl pyrrolidine -a-monocarboxylic acid
GB800565A (en) * 1956-01-23 1958-08-27 Bofors Ab Method of producing n-alkyl-piperidine-ª‡-monocarboxylic acid amides and n-alkyl-pyrrolidine-ª‡-monocarboxylic acid amides
GB824542A (en) * 1957-05-15 1959-12-02 Bofors Ab Method of producing n-alkyl-piperidine-alpha-monocarboxylic acid amides
GB869978A (en) * 1958-03-13 1961-06-07 Bofors Ab Method of producing n-alkyl-and-cycloalkyl-piperidine carboxylic acid amides
GB949729A (en) * 1960-11-15 1964-02-19 Bofors Ab Substituted-piperidine carboxylic acid amide salts and their preparation
SE341404B (es) * 1967-05-18 1971-12-27 Sterling Drug Inc
CH491915A (de) * 1967-06-28 1970-06-15 Geigy Ag J R Verfahren zur Herstellung von neuen Piperidinderivaten
US3879382A (en) * 1971-08-27 1975-04-22 Teijin Ltd Process for the recovery of D- or L-{60 -amino-{68 -caprolactam hydrochloride of enhanced optical purity from mixtures of D- and L-{60 -amino-{68 -caprolactam hydrochloride
SE7607114L (sv) * 1976-06-22 1977-12-23 Bofors Ab Sett att framstella hydrokloriden av n-metylpiperidin-2-karbonsyra-2,6-xyllidid
SE431092B (sv) * 1979-07-10 1984-01-16 Thuresson Af Ekenstam Bo Terapeutiskt aktiva, substituerade piperidinkarboxianilider
DE3379266D1 (en) * 1983-08-01 1989-04-06 Astra Laekemedel Ab L-n-n-propylpipecolic acid-2,6-xylidide and method for preparing the same

Also Published As

Publication number Publication date
PT84041B (pt) 1989-09-14
NO864858L (no) 1987-07-06
IE59061B1 (en) 1993-12-15
SE451840B (sv) 1987-11-02
IE870004L (en) 1987-07-03
US4870086A (en) 1989-09-26
EG17867A (en) 1991-03-30
LV5765A4 (lv) 1996-12-20
NO864858D0 (no) 1986-12-03
ES2036179T3 (es) 1993-05-16
JPH07598B2 (ja) 1995-01-11
AU6644986A (en) 1987-07-09
PT84041A (en) 1987-01-01
SE8600017D0 (sv) 1986-01-03
AU592392B2 (en) 1990-01-11
SG117292G (en) 1993-01-29
BG62066B2 (bg) 1999-01-29
JPS62158251A (ja) 1987-07-14
NZ218615A (en) 1989-07-27
DE3674582D1 (de) 1990-10-31
MY101132A (en) 1991-07-31
DK287A (da) 1987-07-04
NO1997009I1 (no) 1997-08-18
LV5765B4 (lv) 1997-06-20
SE8600017L (sv) 1987-07-04
FI870003A0 (fi) 1987-01-02
NL960005I2 (nl) 1997-10-01
LU88843I2 (fr) 1997-03-14
FI83075C (fi) 1991-05-27
ZA868600B (en) 1987-08-26
EP0239710A1 (en) 1987-10-07
CY1680A (en) 1993-10-10
KR940008302B1 (ko) 1994-09-12
HK5493A (en) 1993-01-29
DK287D0 (da) 1987-01-02
DK171378B1 (da) 1996-10-07
FI83075B (fi) 1991-02-15
NL960005I1 (nl) 1996-09-02
EP0239710B1 (en) 1990-09-26
KR870007118A (ko) 1987-08-14
GR3002516T3 (en) 1993-01-25
AR242561A1 (es) 1993-04-30
PH22924A (en) 1989-01-24
FI870003A (fi) 1987-07-04
CA1276154C (en) 1990-11-13
NO170330B (no) 1992-06-29
ATE56956T1 (de) 1990-10-15

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