LV5765B4 - (S)-(-)-1-propil-2',6'-pipekoloksilidida hidrohlorida monohidrats ta iegusanas metode un to satuross farmaceitisks preparats - Google Patents

(S)-(-)-1-propil-2',6'-pipekoloksilidida hidrohlorida monohidrats ta iegusanas metode un to satuross farmaceitisks preparats

Info

Publication number
LV5765B4
LV5765B4 LV960261A LV960261A LV5765B4 LV 5765 B4 LV5765 B4 LV 5765B4 LV 960261 A LV960261 A LV 960261A LV 960261 A LV960261 A LV 960261A LV 5765 B4 LV5765 B4 LV 5765B4
Authority
LV
Latvia
Prior art keywords
pipecoloxylid
propyl
obtaining
pharmaceutical preparation
hydrochloride monohydrate
Prior art date
Application number
LV960261A
Other languages
English (en)
Latvian (lv)
Other versions
LV5765A4 (lv
Inventor
Rune Verner Sandberg
Original Assignee
Astra Laekemedel Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20363001&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LV5765(B4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astra Laekemedel Ab filed Critical Astra Laekemedel Ab
Publication of LV5765A4 publication Critical patent/LV5765A4/xx
Publication of LV5765B4 publication Critical patent/LV5765B4/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
LV960261A 1986-01-03 1996-07-17 (S)-(-)-1-propil-2',6'-pipekoloksilidida hidrohlorida monohidrats ta iegusanas metode un to satuross farmaceitisks preparats LV5765B4 (lv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8600017A SE451840B (sv) 1986-01-03 1986-01-03 Optiskt rent monohydrat av s-(-)-1-propyl-2',6'-pipekoloxylididhydroklorid, sett att framstella denna och farmaceutiska beredningar for lokalbedovning
EP86850440A EP0239710B1 (en) 1986-01-03 1986-12-15 (s)-(-)-1-propyl-2',6'-pipecoloxylidide hydrochloride monohydrate, process for its preparation and pharmaceutical preparation containing it

Publications (2)

Publication Number Publication Date
LV5765A4 LV5765A4 (lv) 1996-12-20
LV5765B4 true LV5765B4 (lv) 1997-06-20

Family

ID=20363001

Family Applications (1)

Application Number Title Priority Date Filing Date
LV960261A LV5765B4 (lv) 1986-01-03 1996-07-17 (S)-(-)-1-propil-2',6'-pipekoloksilidida hidrohlorida monohidrats ta iegusanas metode un to satuross farmaceitisks preparats

Country Status (29)

Country Link
US (1) US4870086A (es)
EP (1) EP0239710B1 (es)
JP (1) JPH07598B2 (es)
KR (1) KR940008302B1 (es)
AR (1) AR242561A1 (es)
AT (1) ATE56956T1 (es)
AU (1) AU592392B2 (es)
BG (1) BG62066B2 (es)
CA (1) CA1276154C (es)
CY (1) CY1680A (es)
DE (1) DE3674582D1 (es)
DK (1) DK171378B1 (es)
EG (1) EG17867A (es)
ES (1) ES2036179T3 (es)
FI (1) FI83075C (es)
GR (1) GR3002516T3 (es)
HK (1) HK5493A (es)
IE (1) IE59061B1 (es)
LU (1) LU88843I2 (es)
LV (1) LV5765B4 (es)
MY (1) MY101132A (es)
NL (1) NL960005I2 (es)
NO (2) NO170330C (es)
NZ (1) NZ218615A (es)
PH (1) PH22924A (es)
PT (1) PT84041B (es)
SE (1) SE451840B (es)
SG (1) SG117292G (es)
ZA (1) ZA868600B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL98392A (en) * 1990-06-07 1996-01-19 Wellcome Found History of indole, their preparation and the pharmaceutical preparations containing them
ES2082703B1 (es) * 1993-11-04 1996-12-16 Inst Investigacion Desarrollo Nuevos derivados de ciclopropilo, procedimientos para su preparacion y aplicaciones.
US5834490A (en) * 1993-11-04 1998-11-10 Instituto De Investigacion Y Desarrolo Quimico Biologico, S.A. Cyclopropyl derivatives, preparation method there-of and applications
ES2173194T3 (es) * 1994-09-23 2002-10-16 Darwin Discovery Ltd Procedimiento de racemizacion utilizado para la preparacion de levobupivacaina y sus analogos.
SE9501808D0 (sv) * 1995-05-16 1995-05-16 Astra Ab New process
US7799337B2 (en) 1997-07-21 2010-09-21 Levin Bruce H Method for directed intranasal administration of a composition
SE9800139D0 (sv) 1998-01-21 1998-01-21 Astra Ab New use
BRPI0104491B8 (pt) * 2001-10-10 2021-05-25 Cristalia Produtos Quim Farmaceuticos Ltda n-(2,6-dimetilfenil)-1-propil-2-piperidinocarboxamida; processo de obtenção dos enantiômeros; mistura não racêmica dos anantiômeros e seu processo de obtenção e composição farmacêutica.
US20060270708A1 (en) * 2005-05-25 2006-11-30 Navinta Llc Novel process for preparation of isotonic aqueous injection of ropivacaine
US7683175B2 (en) * 2005-06-06 2010-03-23 Navinta, Llc Process of making optically pure L-pipecolic acid and process of making anesthetics and intermediates therefrom
JP2009535327A (ja) * 2006-04-25 2009-10-01 ディシュマン・ファーマシューティカルズ・アンド・ケミカルズ・リミテッド ロピバカイン塩酸塩無水物およびその調製
EP2234974B1 (en) * 2008-01-15 2012-04-25 Pharmathen S.A. Process for the preparation of (s)-1-alkyl-2',6'-pipecoloxylidide compound
US8473062B2 (en) 2008-05-01 2013-06-25 Autonomic Technologies, Inc. Method and device for the treatment of headache
US8412336B2 (en) 2008-12-29 2013-04-02 Autonomic Technologies, Inc. Integrated delivery and visualization tool for a neuromodulation system
US9320908B2 (en) 2009-01-15 2016-04-26 Autonomic Technologies, Inc. Approval per use implanted neurostimulator
US8494641B2 (en) 2009-04-22 2013-07-23 Autonomic Technologies, Inc. Implantable neurostimulator with integral hermetic electronic enclosure, circuit substrate, monolithic feed-through, lead assembly and anchoring mechanism
CN102093284B (zh) * 2010-12-29 2013-05-08 宜昌人福药业有限责任公司 富集哌啶-2-甲酰苯胺类旋光化合物的方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2248018A (en) * 1939-03-30 1941-07-01 Winthrop Chem Co Inc 4-aryl-piperidine-ketones and a process of preparing them
GB775749A (en) * 1955-04-06 1957-05-29 Bofors Ab Method of preparing amides of n-alkyl piperidine monocarboxylic acid and n-alkyl pyrrolidine -a-monocarboxylic acid
GB775750A (en) * 1955-04-28 1957-05-29 Bofors Ab Method of preparing amides of n-alkyl piperidine mono-carboxylic acid and n-alkyl pyrrolidine -a-monocarboxylic acid
US2799679A (en) * 1955-04-28 1957-07-16 Bofors Ab Process of preparing amides of heterocyclic carboxylic acids
GB800565A (en) * 1956-01-23 1958-08-27 Bofors Ab Method of producing n-alkyl-piperidine-ª‡-monocarboxylic acid amides and n-alkyl-pyrrolidine-ª‡-monocarboxylic acid amides
GB824542A (en) * 1957-05-15 1959-12-02 Bofors Ab Method of producing n-alkyl-piperidine-alpha-monocarboxylic acid amides
GB869978A (en) * 1958-03-13 1961-06-07 Bofors Ab Method of producing n-alkyl-and-cycloalkyl-piperidine carboxylic acid amides
GB949729A (en) * 1960-11-15 1964-02-19 Bofors Ab Substituted-piperidine carboxylic acid amide salts and their preparation
SE341404B (es) * 1967-05-18 1971-12-27 Sterling Drug Inc
CH491915A (de) * 1967-06-28 1970-06-15 Geigy Ag J R Verfahren zur Herstellung von neuen Piperidinderivaten
US3879382A (en) * 1971-08-27 1975-04-22 Teijin Ltd Process for the recovery of D- or L-{60 -amino-{68 -caprolactam hydrochloride of enhanced optical purity from mixtures of D- and L-{60 -amino-{68 -caprolactam hydrochloride
SE7607114L (sv) * 1976-06-22 1977-12-23 Bofors Ab Sett att framstella hydrokloriden av n-metylpiperidin-2-karbonsyra-2,6-xyllidid
SE431092B (sv) * 1979-07-10 1984-01-16 Thuresson Af Ekenstam Bo Terapeutiskt aktiva, substituerade piperidinkarboxianilider
EP0151110B1 (en) * 1983-08-01 1989-03-01 Astra Läkemedel Aktiebolag L-n-n-propylpipecolic acid-2,6-xylidide and method for preparing the same

Also Published As

Publication number Publication date
AU592392B2 (en) 1990-01-11
NO1997009I1 (no) 1997-08-18
NO170330C (no) 1992-10-07
ZA868600B (en) 1987-08-26
MY101132A (en) 1991-07-31
CA1276154C (en) 1990-11-13
US4870086A (en) 1989-09-26
DK287D0 (da) 1987-01-02
GR3002516T3 (en) 1993-01-25
SE8600017D0 (sv) 1986-01-03
CY1680A (en) 1993-10-10
NL960005I2 (nl) 1997-10-01
NL960005I1 (nl) 1996-09-02
KR870007118A (ko) 1987-08-14
LV5765A4 (lv) 1996-12-20
NZ218615A (en) 1989-07-27
NO864858L (no) 1987-07-06
ES2036179T3 (es) 1993-05-16
DK171378B1 (da) 1996-10-07
SE8600017L (sv) 1987-07-04
PT84041B (pt) 1989-09-14
FI870003A (fi) 1987-07-04
IE870004L (en) 1987-07-03
AR242561A1 (es) 1993-04-30
KR940008302B1 (ko) 1994-09-12
FI83075C (fi) 1991-05-27
SE451840B (sv) 1987-11-02
AU6644986A (en) 1987-07-09
IE59061B1 (en) 1993-12-15
EP0239710A1 (en) 1987-10-07
BG62066B2 (bg) 1999-01-29
PH22924A (en) 1989-01-24
PT84041A (en) 1987-01-01
JPS62158251A (ja) 1987-07-14
HK5493A (en) 1993-01-29
NO170330B (no) 1992-06-29
FI83075B (fi) 1991-02-15
JPH07598B2 (ja) 1995-01-11
DE3674582D1 (de) 1990-10-31
DK287A (da) 1987-07-04
EG17867A (en) 1991-03-30
FI870003A0 (fi) 1987-01-02
LU88843I2 (fr) 1997-03-14
EP0239710B1 (en) 1990-09-26
SG117292G (en) 1993-01-29
NO864858D0 (no) 1986-12-03
ATE56956T1 (de) 1990-10-15

Similar Documents

Publication Publication Date Title
LV5760A4 (lv) Jauns farmaceitisks preparats peroralai lietosanai
LV5765A4 (lv) (S)-(-)-1-propil-2',6'-pipekoloksilidida hidrohlorida monohidrats ta iegusanas metode un to satuross farmaceitisks preparats
DK52787D0 (da) Laegemiddelpraeparat med protraheret virkning og fremgangsmaade til fremstilling heraf
FI891338A0 (fi) Parannus menetelmään 2',3'-dideoksi-2',3'-didehydronukleosidien valmistamiseksi
PH24749A (en) Piperidine compounds, pharmaceutical composition and method of use thereof
IT8922164A0 (it) Composizione farmaceutica e procedimento per la sua preparazione
IT8767057A0 (it) Composizioni farmaceutiche a cessione prolungata relative forme di dosaggio e procedimento per la loro preparazione
FI894546A (fi) Menetelmä uusien 2'-halogeenimetylideeni-, 2'-etenylideeni- ja 2'-etynyyliadenosiinijohdannaisten valmistamiseksi
NZ222116A (en) 3-propenylcephem derivatives and pharmaceutical compositions; processes for preparation
DK559288A (da) Farmaceutisk praeparat for piperidinoalkanolderivater
IT8722264A0 (it) Procedimento per la preparazione di compresse solubili e/o divisibili e compresse cosi' ottenute.
IT1196499B (it) Procedimento perfezionato per la preparazione di anidride borica
IT1196528B (it) Azolilderivati ad attivita' antifungina
DK624587D0 (da) Farmaceutisk praeparat indeholdende imidazolderivater
GB2195082B (en) Pharmaceutical preparation for veterinary use
DK37589D0 (da) Farmaceutisk praeparat for 4-aroylimidazol-2-oner
DK173287D0 (da) Perhydrothiazepin- og perhydroazepinderivater og fremgangsmaade til fremstilling deraf
IT1216894B (it) Composizione farmaceutica eprocedimento per la sua preparazione.
DK138888D0 (da) Farmaceutisk praeparat
LV5752A4 (lv) Farmaceitisks preparats un metode ta razosanai
IT1222591B (it) 1,4-diidropiridine 2-alchil- ed alchenil-sostituite,metodo per la loro preparazione e composizione farmaceutiche che le contengono
BG42585A1 (en) Derivatives of 2- aminoethylthiophosphoric acid, method for its preparation and use thereof
IT1201174B (it) Soluzione farmaceutica comprendente chelati di l-3,4-diidrossifenil-alfa-metilalanina e procedimento per la sua preparazione
PT84557A (en) Process for the preparation of alkylaminofuranone derivatives and pharmaceutically acceptable salts thereof
PH22996A (en) Dichloroaniline derivatives, pharmaceutical composition containing said compound and method of use thereof