NO164093C - Pyridinoksyd-mellomprodukter og fremgangsmaate for deres fremstilling. - Google Patents
Pyridinoksyd-mellomprodukter og fremgangsmaate for deres fremstilling.Info
- Publication number
- NO164093C NO164093C NO832794A NO832794A NO164093C NO 164093 C NO164093 C NO 164093C NO 832794 A NO832794 A NO 832794A NO 832794 A NO832794 A NO 832794A NO 164093 C NO164093 C NO 164093C
- Authority
- NO
- Norway
- Prior art keywords
- preparation
- pyridinoxyd
- procedures
- intermediate products
- sub
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/68—One oxygen atom attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8204879A SE8204879D0 (sv) | 1982-08-26 | 1982-08-26 | Novel chemical intermediates |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO832794L NO832794L (no) | 1984-02-27 |
| NO164093B NO164093B (no) | 1990-05-21 |
| NO164093C true NO164093C (no) | 1990-08-29 |
Family
ID=20347627
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO832794A NO164093C (no) | 1982-08-26 | 1983-08-02 | Pyridinoksyd-mellomprodukter og fremgangsmaate for deres fremstilling. |
Country Status (28)
| Country | Link |
|---|---|
| US (2) | US4544750A (is) |
| EP (1) | EP0103553B1 (is) |
| JP (1) | JPS5959662A (is) |
| KR (1) | KR880000091B1 (is) |
| AT (1) | ATE40884T1 (is) |
| AU (1) | AU560028B2 (is) |
| CA (1) | CA1234118A (is) |
| CY (1) | CY1328A (is) |
| DD (1) | DD233126A5 (is) |
| DE (2) | DE103553T1 (is) |
| DK (1) | DK381583A (is) |
| ES (1) | ES525122A0 (is) |
| FI (1) | FI79701C (is) |
| GB (1) | GB2126226B (is) |
| GR (1) | GR79374B (is) |
| HK (1) | HK19486A (is) |
| HU (1) | HU189738B (is) |
| IE (1) | IE55865B1 (is) |
| IL (1) | IL69175A (is) |
| IS (1) | IS1438B6 (is) |
| MY (1) | MY8600503A (is) |
| NO (1) | NO164093C (is) |
| NZ (1) | NZ204959A (is) |
| OA (1) | OA07498A (is) |
| PH (1) | PH17786A (is) |
| PT (1) | PT77249B (is) |
| SE (1) | SE8204879D0 (is) |
| ZA (1) | ZA835143B (is) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8404065D0 (sv) * | 1984-08-10 | 1984-08-10 | Haessle Ab | Novel biologically active compounds |
| SE8504409D0 (sv) * | 1985-09-24 | 1985-09-24 | Haessle Ab | Novel chemical intermediates |
| US5221316A (en) * | 1986-04-17 | 1993-06-22 | Imperial Chemical Industries Plc | Fungicides |
| EP0243012B1 (en) * | 1986-04-17 | 1993-01-13 | Imperial Chemical Industries Plc | Pyridyl-acrylic acid ester derivatives, process for their preparation and their use as fungicides |
| US4920230A (en) * | 1987-06-29 | 1990-04-24 | Takeda Chemical Industries, Ltd. | Method of producing nitrogen-containing heteroaromatic compounds having an alkoxy group |
| AT391693B (de) * | 1988-11-15 | 1990-11-12 | Cl Pharma | Verfahren zur herstellung von 3-5-dimethyl-4methoxypyridinderivaten sowie neues zwischenprodukt hierfuer |
| US4965269A (en) * | 1989-12-20 | 1990-10-23 | Ab Hassle | Therapeutically active chloro substituted benzimidazoles |
| ES2026761A6 (es) * | 1990-10-31 | 1992-05-01 | Genesis Para La Investigacion | Procedimiento de obtencion del omeprazol. |
| ES2036948B1 (es) * | 1991-11-21 | 1994-09-01 | Genesis Para La Investigacion | Procedimiento de obtencion de compuestos derivados de piridina. |
| ES2060541B1 (es) * | 1993-02-26 | 1995-11-16 | Vinas Lab | Nuevo procedimiento para la sintesis de un derivado de 2-(2-piridilmetilsufinil) bencimidazol, y nuevos productos intermedios obtenidos con el mismo. |
| SE9301830D0 (sv) * | 1993-05-28 | 1993-05-28 | Ab Astra | New compounds |
| ES2097089B1 (es) * | 1995-02-01 | 1997-12-16 | Esteve Quimica Sa | Procedimiento para la preparacion de 2-hidroximetil-3,5-dimetil-4-metoxipiridina. |
| US6645988B2 (en) | 1996-01-04 | 2003-11-11 | Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
| US5840737A (en) | 1996-01-04 | 1998-11-24 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
| US6489346B1 (en) | 1996-01-04 | 2002-12-03 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
| US6699885B2 (en) | 1996-01-04 | 2004-03-02 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and methods of using same |
| US6437139B1 (en) | 1997-05-06 | 2002-08-20 | Pdi-Research Laboratories, Inc. | Synthesis of pharmaceutically useful pyridine derivatives |
| CA2204580A1 (en) * | 1997-05-06 | 1998-11-06 | Michel Zoghbi | Synthesis of pharmaceutically useful pyridine derivatives |
| GB9717849D0 (en) * | 1997-08-23 | 1997-10-29 | Seal Sands Chemicals Limited | Preparation of pyridene derivatives |
| US6174548B1 (en) | 1998-08-28 | 2001-01-16 | Andrx Pharmaceuticals, Inc. | Omeprazole formulation |
| US6096340A (en) * | 1997-11-14 | 2000-08-01 | Andrx Pharmaceuticals, Inc. | Omeprazole formulation |
| AU1656699A (en) * | 1997-12-24 | 1999-07-19 | Pdi-Research Laboratories, Inc. | Synthesis of pharmaceutically useful pyridine derivatives |
| KR100396431B1 (ko) * | 1998-01-26 | 2003-09-02 | 가부시키가이샤 구라레 | 2-술포닐피리딘 유도체 및 2-[((2-피리딜)메틸)티오]-1ｈ-벤즈이 |
| US6350876B2 (en) | 1998-01-26 | 2002-02-26 | Kuraray Co., Ltd. | 4-chloro-3,5-dimethyl-2-sulfonyl pyridines |
| US6303787B1 (en) | 1998-05-27 | 2001-10-16 | Natco Pharma Limited | Intermediates and an improved process for the preparation of Omeprazole employing the said intermediates |
| AU4387799A (en) * | 1998-06-26 | 2000-01-17 | Russinsky Limited | Pyridine building blocks as intermediates in the synthesis of pharmaceutically active compounds |
| US6733778B1 (en) | 1999-08-27 | 2004-05-11 | Andrx Pharmaceuticals, Inc. | Omeprazole formulation |
| US6362202B1 (en) | 1999-03-02 | 2002-03-26 | Sepracor Inc. | Methods and compositions using (−) norcisapride in combination with proton pump inhibitors or H2 receptor antagonists |
| US6353005B1 (en) | 1999-03-02 | 2002-03-05 | Sepracor, Inc. | Method and compositions using (+) norcisapride in combination with proton pump inhibitors or H2 receptor antagonist |
| US6555139B2 (en) | 1999-06-28 | 2003-04-29 | Wockhardt Europe Limited | Preparation of micron-size pharmaceutical particles by microfluidization |
| US6245913B1 (en) | 1999-06-30 | 2001-06-12 | Wockhardt Europe Limited | Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole |
| US6268385B1 (en) | 1999-08-26 | 2001-07-31 | Robert R. Whittle | Dry blend pharmaceutical formulations |
| US6326384B1 (en) | 1999-08-26 | 2001-12-04 | Robert R. Whittle | Dry blend pharmaceutical unit dosage form |
| US6262086B1 (en) | 1999-08-26 | 2001-07-17 | Robert R. Whittle | Pharmaceutical unit dosage form |
| US6262085B1 (en) | 1999-08-26 | 2001-07-17 | Robert R. Whittle | Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
| US6780880B1 (en) | 1999-08-26 | 2004-08-24 | Robert R. Whittle | FT-Raman spectroscopic measurement |
| US6316020B1 (en) | 1999-08-26 | 2001-11-13 | Robert R. Whittle | Pharmaceutical formulations |
| US6312723B1 (en) | 1999-08-26 | 2001-11-06 | Robert R. Whittle | Pharmaceutical unit dosage form |
| US6369087B1 (en) | 1999-08-26 | 2002-04-09 | Robert R. Whittle | Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
| US6312712B1 (en) | 1999-08-26 | 2001-11-06 | Robert R. Whittle | Method of improving bioavailability |
| GB9921578D0 (en) * | 1999-09-13 | 1999-11-17 | Cipla Limited | Omeprazole synthesis |
| ES2171116B1 (es) * | 2000-04-14 | 2003-08-01 | Esteve Quimica Sa | Procedimiento para la obtencion de derivados de (((piridil sustituido)metil)tio)bencimidazol. |
| WO2003097606A1 (en) * | 2000-07-28 | 2003-11-27 | Herbex, Produtos Químicos, Sa | New method for the preparation of the anti-ulcer compounds omeprazole, lansoprazole and pantoprazole |
| AR035970A1 (es) | 2001-05-11 | 2004-07-28 | Tibotec Pharm Ltd | 2-amino-benzoxazol sulfonamidas inhibidoras de amplio espectro de la hiv proteasa, composicion farmaceutica, metodo "in vitro" para inhibir la replicacion retroviral, y utilizacion de estos compuestos en la manufactura de medicamentos |
| MXPA04007169A (es) * | 2002-01-25 | 2004-10-29 | Santarus Inc | Suministro transmucosal de inhibidores de bomba de protones. |
| FR2848555B1 (fr) | 2002-12-16 | 2006-07-28 | Negma Gild | Enantiomere(-)du tenatoprazole et son application en therapeutique |
| US8993599B2 (en) | 2003-07-18 | 2015-03-31 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
| US8815916B2 (en) | 2004-05-25 | 2014-08-26 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
| US8906940B2 (en) | 2004-05-25 | 2014-12-09 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
| CN100376574C (zh) * | 2006-06-14 | 2008-03-26 | 浙江大学 | 泰妥拉唑的制备方法 |
| EP2114919A2 (en) | 2007-01-31 | 2009-11-11 | Krka Tovarna Zdravil, D.D., Novo Mesto | Process for the preparation of optically pure omeprazole via salt formation with a chiral amine or treatment with an entiomer converting enzyme and chromatographic seperation |
| CN101648907B (zh) * | 2009-09-14 | 2011-08-03 | 南京第一农药集团有限公司 | 2-氯甲基-4-甲氧基-3,5-二甲基吡啶盐酸盐的纯化方法 |
| CN101648912B (zh) * | 2009-09-14 | 2012-07-04 | 南京第一农药集团有限公司 | 一种4-硝基-3,5-二甲基吡啶-n-氧化物的连续化制备方法 |
| CN102603620B (zh) * | 2012-01-13 | 2014-10-29 | 江苏中邦制药有限公司 | 一种氯甲基吡啶或其吡啶衍生物盐酸盐的合成方法 |
| EP4034143A1 (en) | 2019-09-24 | 2022-08-03 | Prolacta Bioscience, Inc. | Compositions and methods for treatment of inflammatory and immune diseases |
| CN112142653B (zh) * | 2020-10-22 | 2022-02-11 | 成都百泉生物医药科技有限公司 | 奥美拉唑中间体的制备方法 |
| CN113307773A (zh) * | 2021-06-17 | 2021-08-27 | 上海毕得医药科技股份有限公司 | 6-溴-3-甲氧基-1-苯基-1h-吲唑及其合成方法和应用 |
| CN114805193B (zh) * | 2022-04-19 | 2023-06-20 | 南京红太阳医药研究院有限公司 | 一种奥美拉唑中间体的制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2735851A (en) * | 1956-02-21 | Alkanolpykroine-n-oxides | ||
| US2663711A (en) * | 1951-12-08 | 1953-12-22 | Du Pont | Process for the preparation of pyridine alcohols from pyridine n-oxides |
| GB1564502A (en) * | 1975-07-31 | 1980-04-10 | Smith Kline French Lab | Guanidines thioureas and 1,1-diamino-2-nitroethylene derivatives |
| SE7804231L (sv) * | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
| US4472409A (en) * | 1981-11-05 | 1984-09-18 | Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung | 2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects |
| JPS58135881A (ja) * | 1981-11-05 | 1983-08-12 | ビク−グルデン・ロムベルク・ヘミツシエ・フアブリク・ゲゼルシヤフト・ミト・ベシユレンクテル・ハフツング | 置換ベンズイミダゾ−ル類、その製造方法と利用、およびこれを含む医薬 |
-
1982
- 1982-08-26 SE SE8204879A patent/SE8204879D0/xx unknown
-
1983
- 1983-06-30 AT AT83850185T patent/ATE40884T1/de not_active IP Right Cessation
- 1983-06-30 DE DE198383850185T patent/DE103553T1/de active Pending
- 1983-06-30 EP EP83850185A patent/EP0103553B1/en not_active Expired
- 1983-06-30 DE DE8383850185T patent/DE3379222D1/de not_active Expired
- 1983-07-06 IL IL69175A patent/IL69175A/xx not_active IP Right Cessation
- 1983-07-06 CA CA000431863A patent/CA1234118A/en not_active Expired
- 1983-07-14 ZA ZA835143A patent/ZA835143B/xx unknown
- 1983-07-20 OA OA58065A patent/OA07498A/xx unknown
- 1983-07-20 AU AU17101/83A patent/AU560028B2/en not_active Expired
- 1983-07-20 NZ NZ204959A patent/NZ204959A/en unknown
- 1983-07-28 IE IE1787/83A patent/IE55865B1/en not_active IP Right Cessation
- 1983-08-02 NO NO832794A patent/NO164093C/no not_active IP Right Cessation
- 1983-08-08 PH PH29368A patent/PH17786A/en unknown
- 1983-08-18 DD DD83254056A patent/DD233126A5/de unknown
- 1983-08-19 DK DK381583A patent/DK381583A/da not_active Application Discontinuation
- 1983-08-24 ES ES525122A patent/ES525122A0/es active Granted
- 1983-08-25 PT PT77249A patent/PT77249B/pt unknown
- 1983-08-25 GB GB08322866A patent/GB2126226B/en not_active Expired
- 1983-08-25 FI FI833047A patent/FI79701C/fi not_active IP Right Cessation
- 1983-08-25 HU HU832987A patent/HU189738B/hu unknown
- 1983-08-25 CY CY1328A patent/CY1328A/xx unknown
- 1983-08-25 JP JP58154250A patent/JPS5959662A/ja active Granted
- 1983-08-26 IS IS2845A patent/IS1438B6/is unknown
- 1983-08-26 US US06/526,900 patent/US4544750A/en not_active Expired - Lifetime
- 1983-08-26 KR KR1019830004003A patent/KR880000091B1/ko not_active IP Right Cessation
- 1983-08-26 GR GR72304A patent/GR79374B/el unknown
-
1985
- 1985-02-01 US US06/697,396 patent/US4620008A/en not_active Expired - Lifetime
-
1986
- 1986-03-20 HK HK194/86A patent/HK19486A/xx not_active IP Right Cessation
- 1986-12-30 MY MY503/86A patent/MY8600503A/xx unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1K | Patent expired |
Free format text: EXPIRED IN AUGUST 2003 |