NO162154C - Analogifremgangsmaate for fremstilling av ureaderivater. - Google Patents
Analogifremgangsmaate for fremstilling av ureaderivater.Info
- Publication number
- NO162154C NO162154C NO855375A NO855375A NO162154C NO 162154 C NO162154 C NO 162154C NO 855375 A NO855375 A NO 855375A NO 855375 A NO855375 A NO 855375A NO 162154 C NO162154 C NO 162154C
- Authority
- NO
- Norway
- Prior art keywords
- groups
- formula
- group
- preparation
- carbon atoms
- Prior art date
Links
- 239000000654 additive Substances 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004103 aminoalkyl group Chemical group 0.000 abstract 1
- 230000000118 anti-neoplastic effect Effects 0.000 abstract 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
- 125000001511 cyclopentyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 150000003672 ureas Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
- C07C275/20—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
- C07C275/24—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB858500615A GB8500615D0 (en) | 1985-01-10 | 1985-01-10 | Organic compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO855375L NO855375L (no) | 1986-07-11 |
| NO162154B NO162154B (no) | 1989-08-07 |
| NO162154C true NO162154C (no) | 1989-11-15 |
Family
ID=10572663
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO855375A NO162154C (no) | 1985-01-10 | 1985-12-30 | Analogifremgangsmaate for fremstilling av ureaderivater. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4650900A (da) |
| EP (1) | EP0187700B1 (da) |
| JP (1) | JPS62123164A (da) |
| AT (1) | ATE52249T1 (da) |
| AU (1) | AU584157B2 (da) |
| CA (1) | CA1244022A (da) |
| DE (1) | DE3670630D1 (da) |
| DK (1) | DK160486C (da) |
| ES (1) | ES8703409A1 (da) |
| FI (1) | FI84598C (da) |
| GB (1) | GB8500615D0 (da) |
| GR (1) | GR860019B (da) |
| NO (1) | NO162154C (da) |
| NZ (1) | NZ214509A (da) |
| PT (1) | PT81808B (da) |
| ZA (1) | ZA859878B (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8914062D0 (en) * | 1989-06-19 | 1989-08-09 | Wellcome Found | Agents for potentiating the effects of antitumour agents and combating multiple drug resistance |
| GB8914040D0 (en) * | 1989-06-19 | 1989-08-09 | Wellcome Found | Agents for potentiating the effects of antitumour agents and combating multiple drug resistance |
| HUT59377A (en) * | 1989-06-19 | 1992-05-28 | Wellcome Found | Process for producing drugs containing new aromatic rings |
| GB8914061D0 (en) * | 1989-06-19 | 1989-08-09 | Wellcome Found | Agents for potentiating the effects of antitumour agents and combating multiple drug resistance |
| GB8914060D0 (en) * | 1989-06-19 | 1989-08-09 | Wellcome Found | Agents for potentiating the effects of antitumour agents and combating multiple drug resistance |
| CA2163325A1 (en) * | 1994-11-21 | 1996-05-22 | Kaneyoshi Kato | Amine compounds, their production and use |
| US5981521A (en) * | 1998-11-13 | 1999-11-09 | Abbott Laboratories | Tetrahydroisoquinoline derivatives as LHRH antagonists |
| CA2351187A1 (en) * | 1998-11-13 | 2000-05-25 | Abbott Laboratories | Tetrahydroisoquinoline derivatives as lhrh antagonists |
| WO2008070496A2 (en) * | 2006-12-01 | 2008-06-12 | Bristol-Myers Squibb Company | N- ( (3-benzyl) -2, 2- (bis-phenyl) -propan-1-amine derivatives as cetp inhibitors for the treatment of atherosclerosis and cardiovascular diseases |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3388158A (en) * | 1965-08-09 | 1968-06-11 | Sterling Drug Inc | 1-(dichlorobenzyl)-3-methyl (or 3, 3-dimethyl) ureas |
| DE2131034A1 (de) * | 1971-06-23 | 1973-01-11 | Hoechst Ag | Acylharnstoffe und verfahren zu ihrer herstellung |
| JPS5419943A (en) * | 1977-07-12 | 1979-02-15 | Nippon Tokushu Noyaku Seizo Kk | Urea or thiourea compounds, their preparation, and agricultural and horticultural fungicides comprising them as active constituents |
| FR2421891A1 (fr) * | 1977-10-17 | 1979-11-02 | Fabre Sa Pierre | Obtention industrielle d'amides de la pyrrolidine ethyl amine |
| IE50228B1 (en) * | 1979-10-03 | 1986-03-05 | Kefalas As | Nitrosourea derivatives,process for preparing them,and pharmaceutical compositions containing them |
-
1985
- 1985-01-10 GB GB858500615A patent/GB8500615D0/en active Pending
- 1985-12-10 NZ NZ214509A patent/NZ214509A/xx unknown
- 1985-12-13 FI FI854945A patent/FI84598C/fi not_active IP Right Cessation
- 1985-12-30 US US06/814,664 patent/US4650900A/en not_active Expired - Fee Related
- 1985-12-30 ZA ZA859878A patent/ZA859878B/xx unknown
- 1985-12-30 NO NO855375A patent/NO162154C/no unknown
-
1986
- 1986-01-06 DE DE8686300030T patent/DE3670630D1/de not_active Expired - Lifetime
- 1986-01-06 AT AT86300030T patent/ATE52249T1/de not_active IP Right Cessation
- 1986-01-06 EP EP86300030A patent/EP0187700B1/en not_active Expired - Lifetime
- 1986-01-07 CA CA000499163A patent/CA1244022A/en not_active Expired
- 1986-01-07 GR GR860019A patent/GR860019B/el unknown
- 1986-01-07 DK DK005086A patent/DK160486C/da active
- 1986-01-08 PT PT81808A patent/PT81808B/pt not_active IP Right Cessation
- 1986-01-09 ES ES550744A patent/ES8703409A1/es not_active Expired
- 1986-01-09 AU AU52157/86A patent/AU584157B2/en not_active Ceased
- 1986-01-10 JP JP61002340A patent/JPS62123164A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA1244022A (en) | 1988-11-01 |
| JPS62123164A (ja) | 1987-06-04 |
| DK5086D0 (da) | 1986-01-07 |
| EP0187700A1 (en) | 1986-07-16 |
| FI854945A0 (fi) | 1985-12-13 |
| DK5086A (da) | 1986-07-11 |
| NO855375L (no) | 1986-07-11 |
| DE3670630D1 (de) | 1990-05-31 |
| AU584157B2 (en) | 1989-05-18 |
| GR860019B (en) | 1986-04-29 |
| NO162154B (no) | 1989-08-07 |
| PT81808B (pt) | 1987-11-30 |
| EP0187700B1 (en) | 1990-04-25 |
| ES8703409A1 (es) | 1987-02-16 |
| PT81808A (en) | 1986-02-01 |
| NZ214509A (en) | 1988-08-30 |
| ES550744A0 (es) | 1987-02-16 |
| FI854945L (fi) | 1986-07-11 |
| DK160486B (da) | 1991-03-18 |
| AU5215786A (en) | 1986-07-17 |
| FI84598B (fi) | 1991-09-13 |
| FI84598C (fi) | 1991-12-27 |
| ZA859878B (en) | 1986-11-26 |
| ATE52249T1 (de) | 1990-05-15 |
| US4650900A (en) | 1987-03-17 |
| DK160486C (da) | 1991-08-26 |
| GB8500615D0 (en) | 1985-02-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE3873612D1 (de) | Dithioacetal-verbindungen, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen. | |
| NO166585C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive substituerte imidazoler. | |
| HUT68721A (en) | Benzofuran and benzizoxazole derivatives, pharmaceutical composition containing said compounds as active agent and process for preparing them | |
| FR2592879B1 (fr) | Nouveaux derives de la decahydroquinoleine, leur procede de preparation, les intermediaires de preparation, leur application a titre de medicaments et les compositions les renfermant | |
| HUT36113A (en) | Process for preparing dihydro-pyridibes with anti-ischaemic activity and blood pressure decreasing effect and pharmaceutical compositions containing such compounds | |
| ES519491A0 (es) | Un metodo para preparar compuesto de piridilo. | |
| NO162154C (no) | Analogifremgangsmaate for fremstilling av ureaderivater. | |
| DE68917357D1 (de) | Derivate der Coffeinsäure und pharmazeutische Zusammensetzungen, die sie enthalten. | |
| ATE48994T1 (de) | Benzimidazol-derivat, verfahren zu seiner herstellung und pharmazeutische zusammensetzung. | |
| AU8295887A (en) | New indane derivatives, the process for preparing them and the new intermediates thereby obtained, their application as medicinal products and the compositions containing them | |
| NO150316C (no) | Analogifremgangsmaate ved fremstilling av terapeutisk aktive nitrosoureaderivater | |
| ES556048A0 (es) | Un procedimiento para la preparacion de un derivado de tiazolidina. | |
| NZ234450A (en) | Substituted pyrrolo(2,1-b)thiazole derivatives, intermediates and pharmaceutical compositions | |
| ES8105286A1 (es) | Un procedimiento para la preparacion de nuevos derivados de dihidropiridina. |