PT81808B - Processo para a preparacao de derivados de aminoalquilo substituido ureia e dos seus sais de adicao de acido - Google Patents

Processo para a preparacao de derivados de aminoalquilo substituido ureia e dos seus sais de adicao de acido

Info

Publication number
PT81808B
PT81808B PT81808A PT8180886A PT81808B PT 81808 B PT81808 B PT 81808B PT 81808 A PT81808 A PT 81808A PT 8180886 A PT8180886 A PT 8180886A PT 81808 B PT81808 B PT 81808B
Authority
PT
Portugal
Prior art keywords
groups
formula
preparation
acid addition
addition salts
Prior art date
Application number
PT81808A
Other languages
English (en)
Other versions
PT81808A (en
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of PT81808A publication Critical patent/PT81808A/pt
Publication of PT81808B publication Critical patent/PT81808B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/04Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
    • C07C275/20Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C07C275/24Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PT81808A 1985-01-10 1986-01-08 Processo para a preparacao de derivados de aminoalquilo substituido ureia e dos seus sais de adicao de acido PT81808B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858500615A GB8500615D0 (en) 1985-01-10 1985-01-10 Organic compounds

Publications (2)

Publication Number Publication Date
PT81808A PT81808A (en) 1986-02-01
PT81808B true PT81808B (pt) 1987-11-30

Family

ID=10572663

Family Applications (1)

Application Number Title Priority Date Filing Date
PT81808A PT81808B (pt) 1985-01-10 1986-01-08 Processo para a preparacao de derivados de aminoalquilo substituido ureia e dos seus sais de adicao de acido

Country Status (16)

Country Link
US (1) US4650900A (pt)
EP (1) EP0187700B1 (pt)
JP (1) JPS62123164A (pt)
AT (1) ATE52249T1 (pt)
AU (1) AU584157B2 (pt)
CA (1) CA1244022A (pt)
DE (1) DE3670630D1 (pt)
DK (1) DK160486C (pt)
ES (1) ES8703409A1 (pt)
FI (1) FI84598C (pt)
GB (1) GB8500615D0 (pt)
GR (1) GR860019B (pt)
NO (1) NO162154C (pt)
NZ (1) NZ214509A (pt)
PT (1) PT81808B (pt)
ZA (1) ZA859878B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8914061D0 (en) * 1989-06-19 1989-08-09 Wellcome Found Agents for potentiating the effects of antitumour agents and combating multiple drug resistance
NZ234110A (en) * 1989-06-19 1993-01-27 Wellcome Found Dibenzoazepine, -oxepine and -cycloheptane substituted alkylidene amines; pharmaceutical compositions containing such compounds or various other aryl substituted amines
GB8914062D0 (en) * 1989-06-19 1989-08-09 Wellcome Found Agents for potentiating the effects of antitumour agents and combating multiple drug resistance
GB8914040D0 (en) * 1989-06-19 1989-08-09 Wellcome Found Agents for potentiating the effects of antitumour agents and combating multiple drug resistance
GB8914060D0 (en) * 1989-06-19 1989-08-09 Wellcome Found Agents for potentiating the effects of antitumour agents and combating multiple drug resistance
CA2163325A1 (en) * 1994-11-21 1996-05-22 Kaneyoshi Kato Amine compounds, their production and use
US5981521A (en) * 1998-11-13 1999-11-09 Abbott Laboratories Tetrahydroisoquinoline derivatives as LHRH antagonists
CA2351187A1 (en) * 1998-11-13 2000-05-25 Abbott Laboratories Tetrahydroisoquinoline derivatives as lhrh antagonists
CN101663262B (zh) * 2006-12-01 2014-03-26 百时美施贵宝公司 用于治疗动脉粥样硬化和心血管疾病的作为cetp抑制剂的n-(3-苄基)-2,2-(二苯基)-丙-1胺衍生物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3388158A (en) * 1965-08-09 1968-06-11 Sterling Drug Inc 1-(dichlorobenzyl)-3-methyl (or 3, 3-dimethyl) ureas
DE2131034A1 (de) * 1971-06-23 1973-01-11 Hoechst Ag Acylharnstoffe und verfahren zu ihrer herstellung
JPS5419943A (en) * 1977-07-12 1979-02-15 Nippon Tokushu Noyaku Seizo Kk Urea or thiourea compounds, their preparation, and agricultural and horticultural fungicides comprising them as active constituents
FR2421891A1 (fr) * 1977-10-17 1979-11-02 Fabre Sa Pierre Obtention industrielle d'amides de la pyrrolidine ethyl amine
IE50228B1 (en) * 1979-10-03 1986-03-05 Kefalas As Nitrosourea derivatives,process for preparing them,and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
GR860019B (en) 1986-04-29
CA1244022A (en) 1988-11-01
ES8703409A1 (es) 1987-02-16
FI854945A (fi) 1986-07-11
EP0187700A1 (en) 1986-07-16
DE3670630D1 (de) 1990-05-31
NO855375L (no) 1986-07-11
ZA859878B (en) 1986-11-26
PT81808A (en) 1986-02-01
FI84598B (fi) 1991-09-13
NO162154C (no) 1989-11-15
NZ214509A (en) 1988-08-30
AU584157B2 (en) 1989-05-18
DK5086D0 (da) 1986-01-07
DK160486B (da) 1991-03-18
ATE52249T1 (de) 1990-05-15
FI854945A0 (fi) 1985-12-13
GB8500615D0 (en) 1985-02-13
DK5086A (da) 1986-07-11
JPS62123164A (ja) 1987-06-04
US4650900A (en) 1987-03-17
NO162154B (no) 1989-08-07
ES550744A0 (es) 1987-02-16
DK160486C (da) 1991-08-26
AU5215786A (en) 1986-07-17
EP0187700B1 (en) 1990-04-25
FI84598C (fi) 1991-12-27

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PT81808B (pt) Processo para a preparacao de derivados de aminoalquilo substituido ureia e dos seus sais de adicao de acido
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