NO157330C - Analogifremgangsmaate for fremstilling av farmakologisk aktive 3-metylflavon-8-karboksylsyreestere. - Google Patents

Analogifremgangsmaate for fremstilling av farmakologisk aktive 3-metylflavon-8-karboksylsyreestere.

Info

Publication number
NO157330C
NO157330C NO822127A NO822127A NO157330C NO 157330 C NO157330 C NO 157330C NO 822127 A NO822127 A NO 822127A NO 822127 A NO822127 A NO 822127A NO 157330 C NO157330 C NO 157330C
Authority
NO
Norway
Prior art keywords
methylflavon
preparation
carboxylic acid
acid esters
pharmacologically active
Prior art date
Application number
NO822127A
Other languages
English (en)
Norwegian (no)
Other versions
NO157330B (no
NO822127L (no
Inventor
Dante Nardi
Alberto Tajana
Renzo Pennini
Pietro Cazzulani
Gabriele Graziani
Silvano Casadio
Original Assignee
Recordati Chem Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati Chem Pharm filed Critical Recordati Chem Pharm
Publication of NO822127L publication Critical patent/NO822127L/no
Publication of NO157330B publication Critical patent/NO157330B/no
Publication of NO157330C publication Critical patent/NO157330C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/12—Oxygen atoms acylated by aromatic or heteroaromatic carboxylic acids, e.g. cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Anesthesiology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
NO822127A 1981-07-17 1982-06-24 Analogifremgangsmaate for fremstilling av farmakologisk aktive 3-metylflavon-8-karboksylsyreestere. NO157330C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8122158 1981-07-17

Publications (3)

Publication Number Publication Date
NO822127L NO822127L (no) 1983-01-18
NO157330B NO157330B (no) 1987-11-23
NO157330C true NO157330C (no) 1988-03-02

Family

ID=10523330

Family Applications (1)

Application Number Title Priority Date Filing Date
NO822127A NO157330C (no) 1981-07-17 1982-06-24 Analogifremgangsmaate for fremstilling av farmakologisk aktive 3-metylflavon-8-karboksylsyreestere.

Country Status (25)

Country Link
US (1) US4550115A (pt)
EP (1) EP0072620B1 (pt)
JP (1) JPS5835185A (pt)
KR (1) KR870000275B1 (pt)
AR (1) AR231543A1 (pt)
AT (1) ATE16806T1 (pt)
AU (1) AU553322B2 (pt)
CA (1) CA1221969A (pt)
DE (1) DE3267782D1 (pt)
DK (1) DK160498C (pt)
ES (1) ES513993A0 (pt)
FI (1) FI73677C (pt)
GB (1) GB2104507B (pt)
GR (1) GR81300B (pt)
HU (1) HU189601B (pt)
IE (1) IE53525B1 (pt)
IL (1) IL66187A0 (pt)
IT (1) IT1198389B (pt)
NO (1) NO157330C (pt)
NZ (1) NZ200981A (pt)
PH (1) PH18001A (pt)
PT (1) PT75230B (pt)
SG (1) SG77784G (pt)
YU (2) YU136682A (pt)
ZA (1) ZA824335B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58225083A (ja) * 1982-06-23 1983-12-27 Nippon Shinyaku Co Ltd メチルフラボン誘導体
FR2531083B1 (fr) * 1982-06-29 1986-11-28 Sandoz Sa Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments
IT1229856B (it) * 1989-04-20 1991-09-13 Recordati Chem Pharm Compresse a rilascio controllato contenenti flavossato.
EP0558245A1 (en) 1992-02-25 1993-09-01 RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY Heterobicyclic compounds as antagogists of alpha-1 adrenergic and SHT1A receptors
US5605896A (en) * 1992-02-25 1997-02-25 Recordati S.A., Chemical And Pharmaceutical Company Bicyclic heterocyclic derivatives having α1 adrenergic and 5HT1A activities
US5474994A (en) * 1992-05-26 1995-12-12 Recordati S.A., Chemical And Pharmaceutical Company Bicyclic heterocyclic derivatives having α1 -adrenergic and 5HT1A
IT1254469B (it) * 1992-02-25 1995-09-25 Recordati Chem Pharm Derivati benzopiranici e benzotiopiranici
IT1258315B (it) * 1992-04-10 1996-02-22 Recordati Chem Pharm Derivati del flavone
US6087366A (en) * 1996-03-07 2000-07-11 The Trustees Of Columbia University In The City Of New York Use of flavopiridol or a pharmaceutically acceptable salt thereof for inhibiting cell damage or cell death
AU2002347553A1 (en) * 2002-12-23 2004-07-14 Ranbaxy Laboratories Limited Flavaxate derivatives as muscarinic receptor antagonists

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2921070A (en) * 1957-11-05 1960-01-12 Recordati Lab Farmacologico S Basic esters of 3-methylflavone-8-carboxylic acid
US4217351A (en) * 1976-08-04 1980-08-12 Abbott Laboratories Benzopyrano quinuclidines useful as antiglaucoma agents

Also Published As

Publication number Publication date
JPS5835185A (ja) 1983-03-01
NO157330B (no) 1987-11-23
ES8400109A1 (es) 1983-10-16
PT75230B (fr) 1984-07-23
IT1198389B (it) 1988-12-21
EP0072620B1 (en) 1985-12-04
DK160498C (da) 1991-08-26
GB2104507B (en) 1984-09-19
DK301982A (da) 1983-01-18
DK160498B (da) 1991-03-18
GB2104507A (en) 1983-03-09
IL66187A0 (en) 1982-11-30
YU125184A (en) 1985-04-30
JPH0251914B2 (pt) 1990-11-08
ES513993A0 (es) 1983-10-16
IT8222274A0 (it) 1982-07-07
IE821678L (en) 1983-01-17
ATE16806T1 (de) 1985-12-15
EP0072620A1 (en) 1983-02-23
HU189601B (en) 1986-07-28
US4550115A (en) 1985-10-29
SG77784G (en) 1985-04-26
FI73677B (fi) 1987-07-31
PT75230A (fr) 1982-08-01
AU8609882A (en) 1983-01-20
KR840000521A (ko) 1984-02-25
CA1221969A (en) 1987-05-19
FI822493L (fi) 1983-01-18
ZA824335B (en) 1983-05-25
GR81300B (pt) 1984-12-11
AR231543A1 (es) 1984-12-28
NO822127L (no) 1983-01-18
FI73677C (fi) 1987-11-09
AU553322B2 (en) 1986-07-10
DE3267782D1 (en) 1986-01-16
FI822493A0 (fi) 1982-07-13
IE53525B1 (en) 1988-12-07
KR870000275B1 (ko) 1987-02-23
PH18001A (en) 1985-02-28
NZ200981A (en) 1984-10-19
YU136682A (en) 1985-06-30

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