PH18001A - 3-methylflavone-8-carboxylic acid esters and their compositions and method of use thereof - Google Patents

3-methylflavone-8-carboxylic acid esters and their compositions and method of use thereof

Info

Publication number
PH18001A
PH18001A PH27559A PH27559A PH18001A PH 18001 A PH18001 A PH 18001A PH 27559 A PH27559 A PH 27559A PH 27559 A PH27559 A PH 27559A PH 18001 A PH18001 A PH 18001A
Authority
PH
Philippines
Prior art keywords
methylflavone
compositions
carboxylic acid
acid esters
esters
Prior art date
Application number
PH27559A
Inventor
Dante Nardi
Alberto Tajada
Renzo Pennini
Gabriele Graziani
Silvano Casadio
Pietro Cazzulani
Original Assignee
Recordati Chem Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati Chem Pharm filed Critical Recordati Chem Pharm
Publication of PH18001A publication Critical patent/PH18001A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/12—Oxygen atoms acylated by aromatic or heteroaromatic carboxylic acids, e.g. cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
PH27559A 1981-07-17 1982-07-12 3-methylflavone-8-carboxylic acid esters and their compositions and method of use thereof PH18001A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8122158 1981-07-17

Publications (1)

Publication Number Publication Date
PH18001A true PH18001A (en) 1985-02-28

Family

ID=10523330

Family Applications (1)

Application Number Title Priority Date Filing Date
PH27559A PH18001A (en) 1981-07-17 1982-07-12 3-methylflavone-8-carboxylic acid esters and their compositions and method of use thereof

Country Status (25)

Country Link
US (1) US4550115A (en)
EP (1) EP0072620B1 (en)
JP (1) JPS5835185A (en)
KR (1) KR870000275B1 (en)
AR (1) AR231543A1 (en)
AT (1) ATE16806T1 (en)
AU (1) AU553322B2 (en)
CA (1) CA1221969A (en)
DE (1) DE3267782D1 (en)
DK (1) DK160498C (en)
ES (1) ES513993A0 (en)
FI (1) FI73677C (en)
GB (1) GB2104507B (en)
GR (1) GR81300B (en)
HU (1) HU189601B (en)
IE (1) IE53525B1 (en)
IL (1) IL66187A0 (en)
IT (1) IT1198389B (en)
NO (1) NO157330C (en)
NZ (1) NZ200981A (en)
PH (1) PH18001A (en)
PT (1) PT75230B (en)
SG (1) SG77784G (en)
YU (2) YU136682A (en)
ZA (1) ZA824335B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58225083A (en) * 1982-06-23 1983-12-27 Nippon Shinyaku Co Ltd Methylflavone derivative
FR2531083B1 (en) * 1982-06-29 1986-11-28 Sandoz Sa NOVEL PIPERIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINES
IT1229856B (en) * 1989-04-20 1991-09-13 Recordati Chem Pharm CONTROLLED RELEASE TABS CONTAINING FLAVOSED.
SG65570A1 (en) 1992-02-25 1999-06-22 Recordati Chem Pharm Heterobicyclic compounds
US5474994A (en) * 1992-05-26 1995-12-12 Recordati S.A., Chemical And Pharmaceutical Company Bicyclic heterocyclic derivatives having α1 -adrenergic and 5HT1A
US5605896A (en) * 1992-02-25 1997-02-25 Recordati S.A., Chemical And Pharmaceutical Company Bicyclic heterocyclic derivatives having α1 adrenergic and 5HT1A activities
IT1254469B (en) * 1992-02-25 1995-09-25 Recordati Chem Pharm BENZOPYRANIC AND BENZOTHIOPYRANIC DERIVATIVES
IT1258315B (en) * 1992-04-10 1996-02-22 Recordati Chem Pharm FLAVONE DERIVATIVES
US6087366A (en) * 1996-03-07 2000-07-11 The Trustees Of Columbia University In The City Of New York Use of flavopiridol or a pharmaceutically acceptable salt thereof for inhibiting cell damage or cell death
AU2002347553A1 (en) * 2002-12-23 2004-07-14 Ranbaxy Laboratories Limited Flavaxate derivatives as muscarinic receptor antagonists

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2921070A (en) * 1957-11-05 1960-01-12 Recordati Lab Farmacologico S Basic esters of 3-methylflavone-8-carboxylic acid
US4217351A (en) * 1976-08-04 1980-08-12 Abbott Laboratories Benzopyrano quinuclidines useful as antiglaucoma agents

Also Published As

Publication number Publication date
FI73677B (en) 1987-07-31
GR81300B (en) 1984-12-11
GB2104507B (en) 1984-09-19
ES8400109A1 (en) 1983-10-16
NO157330B (en) 1987-11-23
HU189601B (en) 1986-07-28
DK160498B (en) 1991-03-18
ZA824335B (en) 1983-05-25
KR840000521A (en) 1984-02-25
IT1198389B (en) 1988-12-21
US4550115A (en) 1985-10-29
PT75230B (en) 1984-07-23
IL66187A0 (en) 1982-11-30
NO157330C (en) 1988-03-02
DK160498C (en) 1991-08-26
CA1221969A (en) 1987-05-19
DK301982A (en) 1983-01-18
NO822127L (en) 1983-01-18
AR231543A1 (en) 1984-12-28
DE3267782D1 (en) 1986-01-16
PT75230A (en) 1982-08-01
IE821678L (en) 1983-01-17
JPH0251914B2 (en) 1990-11-08
ES513993A0 (en) 1983-10-16
NZ200981A (en) 1984-10-19
AU8609882A (en) 1983-01-20
IT8222274A0 (en) 1982-07-07
SG77784G (en) 1985-04-26
FI73677C (en) 1987-11-09
YU125184A (en) 1985-04-30
FI822493L (en) 1983-01-18
IE53525B1 (en) 1988-12-07
AU553322B2 (en) 1986-07-10
EP0072620A1 (en) 1983-02-23
YU136682A (en) 1985-06-30
FI822493A0 (en) 1982-07-13
EP0072620B1 (en) 1985-12-04
JPS5835185A (en) 1983-03-01
GB2104507A (en) 1983-03-09
ATE16806T1 (en) 1985-12-15
KR870000275B1 (en) 1987-02-23

Similar Documents

Publication Publication Date Title
JPS54135761A (en) 17 betaathiocarboxylic acid esters of 44haloo33oxoandrostt44enes and their manufacture
JPS5436296A (en) Nnsubstituted ester of 9*100dihydrolysergic acid and method for its preparation
IL65629A (en) Preparation of alpha-arylalkanoic acids and esters and salts thereof
PH20430A (en) Carboxylic acid derivatives and pharmaceutical composition and method of use
JPS5750939A (en) Manufacture of unsaturated acid and ester
PH18001A (en) 3-methylflavone-8-carboxylic acid esters and their compositions and method of use thereof
IL63791A0 (en) Preparation of alpha-aryl-alkanoic acids and esters thereof
DE3462792D1 (en) Enhanced 2-hydroxy-4-methylthiobutanoic acid composition and method of preparation
JPS57187397A (en) Manufacture of eicosapentaenoic acid or ester of same
IL64713A0 (en) Preparation of 2,2-dimethyl-3-vinylcyclopropanecarboxylic acids and esters thereof
GB2096136B (en) Esters of mercapto acyl-carnitines process for their preparation and pharmaceutical compositions containing same
IL76698A (en) Esters of 2-bromo-4-methylimidazole-5-carboxylic acid and their use as herbicides
IL66621A0 (en) Preparation of alkoxyvincaminic and alkoxyapovincaminic acid esters
DE3272452D1 (en) Medicinal composition and method of making same
JPS562949A (en) Manufacture of 22cyanoo3*33dimethyll cyclopropanee11carboxylic acid ester and intermediate for carrying out said method
JPS57136551A (en) Chroloformic acid ester of c-alkyltartronic acid alkyl and manufacture
DE3266707D1 (en) Preparation of nitroarylacetic acid esters and derivatives thereof
IL66413A0 (en) Preparation of alpha-hydroxyphophonic acid esters
JPS56158752A (en) Manufacture of methylene-bis-phenylcarbamic acid ester and polymethylene-polyphenylcarbamic acid ester
JPS579743A (en) Manufacture of methaphenoxybenzoic acid and ester
HK74987A (en) Esters of 2-carbamoyloxymethyl-6-hydroxyethyl-2-penem-3-carboxylic acid
JPS56131600A (en) Preparation of calcitroic acid and its ester
GB2134525B (en) Preparation of olean-12-ene-3b 30-diol and esters thereof
PL248925A1 (en) Pesticide and method of manufacture of esters of haloalkylcarbamic acid
JPS57193421A (en) Simultaneous manufacture of dicarboxylate and acid

Legal Events

Date Code Title Description
AT Record of annual fee payments

Year of fee payment: 11