NO155491C - Analogifremgangsmaate ved fremstilling av terapeutisk aktive, substiuerte 4-hydroxytetrahydropyran-2-oner. - Google Patents
Analogifremgangsmaate ved fremstilling av terapeutisk aktive, substiuerte 4-hydroxytetrahydropyran-2-oner.Info
- Publication number
- NO155491C NO155491C NO802431A NO802431A NO155491C NO 155491 C NO155491 C NO 155491C NO 802431 A NO802431 A NO 802431A NO 802431 A NO802431 A NO 802431A NO 155491 C NO155491 C NO 155491C
- Authority
- NO
- Norway
- Prior art keywords
- hydroxytetrahydropyran
- substuated
- oner
- preparation
- therapeutically active
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
- C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C67/347—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by addition to unsaturated carbon-to-carbon bonds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pyrane Compounds (AREA)
- Saccharide Compounds (AREA)
- Steroid Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6757479A | 1979-08-17 | 1979-08-17 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO802431L NO802431L (no) | 1981-02-18 |
| NO155491B NO155491B (no) | 1986-12-29 |
| NO155491C true NO155491C (no) | 1987-04-08 |
Family
ID=22076933
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO802431A NO155491C (no) | 1979-08-17 | 1980-08-14 | Analogifremgangsmaate ved fremstilling av terapeutisk aktive, substiuerte 4-hydroxytetrahydropyran-2-oner. |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP0024348B1 (es) |
| JP (1) | JPS5645470A (es) |
| KR (1) | KR840002170B1 (es) |
| AT (1) | ATE16487T1 (es) |
| AU (1) | AU6108580A (es) |
| CA (1) | CA1137989A (es) |
| CS (1) | CS219921B2 (es) |
| DD (1) | DD152558A5 (es) |
| DE (1) | DE3071230D1 (es) |
| DK (1) | DK353680A (es) |
| ES (1) | ES8106152A1 (es) |
| FI (1) | FI802582A (es) |
| GR (1) | GR69938B (es) |
| HU (1) | HU182190B (es) |
| IE (1) | IE50789B1 (es) |
| IL (1) | IL60751A (es) |
| MA (1) | MA18929A1 (es) |
| NO (1) | NO155491C (es) |
| NZ (1) | NZ194557A (es) |
| PL (2) | PL127979B1 (es) |
| PT (1) | PT71672B (es) |
| YU (1) | YU207180A (es) |
| ZA (1) | ZA805016B (es) |
| ZW (1) | ZW19080A1 (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4440927A (en) * | 1981-06-19 | 1984-04-03 | Merck & Co., Inc. | Process for preparing inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase via a chiral synthon |
| EP0068038B1 (en) * | 1981-06-29 | 1985-09-25 | Merck & Co. Inc. | (+)-(4r,6s)-(e)-6-(2-(4'-fluoro-3,3',5-trimethyl-(1,1'-biphenyl)-2-yl)ethenyl)-3,4,5,6-tetrahydro-4-hydroxy-2h-pyran-2-one, a process for preparing and a pharmaceutical composition containing the same |
| US4588820A (en) * | 1984-06-11 | 1986-05-13 | Merck & Co., Inc. | Process for epimerization at C6 of 3,4,5,6-tetrahydro-2H-pyran-2-one |
| US4647576A (en) * | 1984-09-24 | 1987-03-03 | Warner-Lambert Company | Trans-6-[2-(substitutedpyrrol-1-yl)alkyl]-pyran-2-one inhibitors of cholesterol synthesis |
| DE3615620A1 (de) * | 1986-05-09 | 1987-11-12 | Hoechst Ag | 4(r)-substituierte 6(s)-phenoxymethyl-, 6(s)-(beta)-phenylaethyl-und 6(s)-(beta)-styryl-tetrahydropyran-2-one, ein hochstereoselektives verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen und ihre verwendung |
| US4897490A (en) * | 1987-02-25 | 1990-01-30 | Bristol-Meyers Company | Antihypercholesterolemic tetrazole compounds |
| US4898949A (en) * | 1987-02-25 | 1990-02-06 | Bristol-Myers Company | Intermediates for the preparation of antihypercholesterolemic tetrazole compounds |
| US5169976A (en) * | 1987-11-25 | 1992-12-08 | Pfizer Inc. | N-(biphenylmethyl)-3-hydroxyglutaramic acid and derivatives as hypocholesterolemic agents |
| FI94339C (fi) | 1989-07-21 | 1995-08-25 | Warner Lambert Co | Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi |
| US5093363A (en) * | 1989-08-22 | 1992-03-03 | Shionogi & Co., Ltd. | 2,4,6-substituted phenol derivatives |
| JP3171931B2 (ja) * | 1992-06-02 | 2001-06-04 | 高砂香料工業株式会社 | （Ｒ）−（−）−４−シアノ−３−ヒドロキシ酪酸ｔ−ブチルエステル及びその製造方法 |
| IL129871A (en) * | 1994-05-06 | 2003-11-23 | Pharmacia & Upjohn Inc | Process for preparing 4-phenyl-substituted octanoyl-oxazolidin-2-one intermediates that are useful for preparing pyran-2-ones useful for treating retroviral infections |
| RU2563831C1 (ru) * | 2014-10-13 | 2015-09-20 | Федеральное государственное бюджетное учреждение науки Иркутский институт химии им. А.Е. Фаворского Сибирского отделения Российской академии наук | Применение протатран 4-хлор-2-метилфеноксиацетата (хлоркрезацина) для угнетения активности холестеролэстеразы |
| EP3277274B1 (en) | 2015-04-01 | 2024-06-12 | Cedars-Sinai Medical Center | Anti-methanogenic lovastatin analogs or derivatives and uses thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS53147073A (en) * | 1977-05-24 | 1978-12-21 | Sankyo Co Ltd | Mevalonolactone derivatives |
| JPS5559180A (en) * | 1978-10-30 | 1980-05-02 | Sankyo Co Ltd | 4-hydroxy-2-pyrone ring compound, its preparation, and remedy for hyperlipemia comprising it as active constituent |
-
1980
- 1980-08-04 NZ NZ194557A patent/NZ194557A/en unknown
- 1980-08-04 IL IL60751A patent/IL60751A/xx unknown
- 1980-08-05 AU AU61085/80A patent/AU6108580A/en not_active Abandoned
- 1980-08-07 PT PT71672A patent/PT71672B/pt unknown
- 1980-08-07 MA MA19129A patent/MA18929A1/fr unknown
- 1980-08-11 KR KR1019800003182A patent/KR840002170B1/ko active
- 1980-08-12 CS CS805551A patent/CS219921B2/cs unknown
- 1980-08-12 GR GR62660A patent/GR69938B/el unknown
- 1980-08-14 DD DD80223335A patent/DD152558A5/de unknown
- 1980-08-14 NO NO802431A patent/NO155491C/no unknown
- 1980-08-14 ES ES494301A patent/ES8106152A1/es not_active Expired
- 1980-08-14 DE DE8080104807T patent/DE3071230D1/de not_active Expired
- 1980-08-14 AT AT80104807T patent/ATE16487T1/de not_active IP Right Cessation
- 1980-08-14 EP EP80104807A patent/EP0024348B1/en not_active Expired
- 1980-08-15 YU YU02071/80A patent/YU207180A/xx unknown
- 1980-08-15 CA CA000358416A patent/CA1137989A/en not_active Expired
- 1980-08-15 HU HU802042A patent/HU182190B/hu not_active IP Right Cessation
- 1980-08-15 FI FI802582A patent/FI802582A/fi not_active Application Discontinuation
- 1980-08-15 ZW ZW190/80A patent/ZW19080A1/xx unknown
- 1980-08-15 ZA ZA00805016A patent/ZA805016B/xx unknown
- 1980-08-15 JP JP11186880A patent/JPS5645470A/ja active Granted
- 1980-08-15 IE IE1732/80A patent/IE50789B1/en unknown
- 1980-08-15 DK DK353680A patent/DK353680A/da not_active Application Discontinuation
- 1980-08-16 PL PL1980226285A patent/PL127979B1/pl unknown
- 1980-08-16 PL PL1980238108A patent/PL132249B1/pl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL60751A (en) | 1985-04-30 |
| NO802431L (no) | 1981-02-18 |
| DK353680A (da) | 1981-02-19 |
| NZ194557A (en) | 1984-09-28 |
| FI802582A (fi) | 1981-02-18 |
| DE3071230D1 (en) | 1985-12-19 |
| KR830003465A (ko) | 1983-06-20 |
| ES494301A0 (es) | 1981-07-16 |
| JPH0257550B2 (es) | 1990-12-05 |
| ZW19080A1 (en) | 1982-03-17 |
| IE801732L (en) | 1981-02-17 |
| YU207180A (en) | 1983-02-28 |
| CS219921B2 (en) | 1983-03-25 |
| IE50789B1 (en) | 1986-07-23 |
| JPS5645470A (en) | 1981-04-25 |
| AU6108580A (en) | 1981-02-19 |
| EP0024348A1 (en) | 1981-03-04 |
| PT71672B (en) | 1982-01-22 |
| ATE16487T1 (de) | 1985-11-15 |
| PT71672A (en) | 1980-09-01 |
| PL226285A1 (es) | 1981-03-27 |
| PL132249B1 (en) | 1985-02-28 |
| HU182190B (en) | 1983-12-28 |
| CA1137989A (en) | 1982-12-21 |
| EP0024348B1 (en) | 1985-11-13 |
| KR840002170B1 (ko) | 1984-11-26 |
| MA18929A1 (fr) | 1981-04-01 |
| NO155491B (no) | 1986-12-29 |
| ZA805016B (en) | 1982-03-31 |
| IL60751A0 (en) | 1980-10-26 |
| ES8106152A1 (es) | 1981-07-16 |
| DD152558A5 (de) | 1981-12-02 |
| PL127979B1 (en) | 1983-12-31 |
| GR69938B (es) | 1982-07-21 |
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