NO153176C - Analogifremgangsmaate ved fremstilling av den terapeutisk virksomme cis-isomer av morfolinderivater. - Google Patents

Analogifremgangsmaate ved fremstilling av den terapeutisk virksomme cis-isomer av morfolinderivater.

Info

Publication number
NO153176C
NO153176C NO802453A NO802453A NO153176C NO 153176 C NO153176 C NO 153176C NO 802453 A NO802453 A NO 802453A NO 802453 A NO802453 A NO 802453A NO 153176 C NO153176 C NO 153176C
Authority
NO
Norway
Prior art keywords
isoms
preparation
therapeutically effective
morpholine derivatives
analogy procedure
Prior art date
Application number
NO802453A
Other languages
English (en)
Norwegian (no)
Other versions
NO802453L (no
NO153176B (no
Inventor
Albert Pfiffner
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH756079A external-priority patent/CH644113A5/de
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO802453L publication Critical patent/NO802453L/no
Publication of NO153176B publication Critical patent/NO153176B/no
Publication of NO153176C publication Critical patent/NO153176C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO802453A 1979-08-17 1980-08-15 Analogifremgangsmaate ved fremstilling av den terapeutisk virksomme cis-isomer av morfolinderivater. NO153176C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH756079A CH644113A5 (en) 1979-08-17 1979-08-17 N-substituted 2,6-dimethylmorpholine compounds
CH418780 1980-05-29

Publications (3)

Publication Number Publication Date
NO802453L NO802453L (no) 1981-02-18
NO153176B NO153176B (no) 1985-10-21
NO153176C true NO153176C (no) 1986-01-29

Family

ID=25694874

Family Applications (1)

Application Number Title Priority Date Filing Date
NO802453A NO153176C (no) 1979-08-17 1980-08-15 Analogifremgangsmaate ved fremstilling av den terapeutisk virksomme cis-isomer av morfolinderivater.

Country Status (31)

Country Link
EP (1) EP0024334B1 (fi)
AR (1) AR225318A1 (fi)
AT (1) ATE4206T1 (fi)
AU (1) AU530398B2 (fi)
BG (1) BG60798B2 (fi)
CA (1) CA1128943A (fi)
CS (1) CS402091A3 (fi)
CU (1) CU35298A (fi)
DE (3) DE3029966A1 (fi)
DK (1) DK150509C (fi)
ES (2) ES8200355A1 (fi)
FI (1) FI69455C (fi)
FR (1) FR2463767B1 (fi)
GB (1) GB2056454B (fi)
HR (1) HRP930340B1 (fi)
HU (1) HU182189B (fi)
IE (1) IE52642B1 (fi)
IL (1) IL60813A (fi)
IT (1) IT1220970B (fi)
LU (1) LU82713A1 (fi)
MC (1) MC1345A1 (fi)
MY (1) MY8500272A (fi)
NL (1) NL8004537A (fi)
NO (1) NO153176C (fi)
NZ (1) NZ194628A (fi)
PH (1) PH15480A (fi)
PT (1) PT71708B (fi)
SE (1) SE447730B (fi)
SI (1) SI8011754A8 (fi)
YU (1) YU43475B (fi)
ZW (1) ZW15780A1 (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3421810A1 (de) * 1984-06-12 1985-12-12 Basf Ag, 6700 Ludwigshafen Phenylalkylamine - bioregulatoren
CA2008775C (en) * 1989-02-24 1998-12-22 Alberto Ferro Nail lacquer
EP0446585A1 (en) * 1990-03-12 1991-09-18 F. Hoffmann-La Roche Ag Control of fungal infections in aquaculture
EP1749825A1 (en) * 2005-07-28 2007-02-07 Galderma S.A. Process of producing amorolfine
EP1749826A1 (en) 2005-07-28 2007-02-07 Galderma S.A. Process of producing bepromoline
EP1842848A1 (en) * 2006-04-03 2007-10-10 Galderma S.A. Process for producing 3-[4-(1,1-dimethyl-propyl)-phenyl]2-methyl-propionaldehyde and cis-4{3-[4-(1,1-dimethyl-propyl)-phenyl]2-methyl-propyl}-2,6-dimethyl-morpholine (amorolfine)
EP1935889A1 (en) * 2006-12-21 2008-06-25 Galderma S.A. Process of producing amorolfine
ITFI20090032A1 (it) 2009-02-20 2010-08-21 Synteco S P A Prodotti Di Sintesi Per L Ind Processo di produzione industriale dell'amorolfina cloridrato

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT354187B (de) * 1976-11-22 1979-12-27 Hoffmann La Roche Fungizides mittel
DE2656747C2 (de) * 1976-12-15 1984-07-05 Basf Ag, 6700 Ludwigshafen Morpholinderivate
ZA792242B (en) * 1978-05-16 1980-05-28 Hoffmann La Roche Heterocyclic compounds
DE2830127A1 (de) * 1978-07-08 1980-01-17 Basf Ag N-arylpropyl-substituierte cyclische amine
DE2830999A1 (de) * 1978-07-14 1980-01-31 Basf Ag Verfahren zur herstellung von stereoisomeren n-aralkyl-2,6-dimethylmorpholinen
DE2965247D1 (en) * 1978-08-08 1983-05-26 Hoffmann La Roche Synthesis of phenyl-propyl morpholine and piperidine derivatives
DE2907614A1 (de) * 1979-02-27 1980-09-04 Basf Ag Optische aktive formen des 1- eckige klammer auf 3-(p-tert.-buthylphenyl)-2- methylpropyl eckige klammer zu -cis-3,5- dimethylmorpholins

Also Published As

Publication number Publication date
ATE4206T1 (de) 1983-08-15
NL8004537A (nl) 1981-02-19
DE3029966A1 (de) 1981-03-26
GB2056454B (en) 1983-11-09
IL60813A0 (en) 1980-10-26
GB2056454A (en) 1981-03-18
EP0024334A1 (de) 1981-03-04
IE52642B1 (en) 1988-01-06
PT71708B (en) 1982-04-06
MY8500272A (en) 1985-12-31
YU43475B (en) 1989-08-31
HRP930340B1 (en) 1996-12-31
EP0024334B1 (de) 1983-07-20
DE3064267D1 (en) 1983-08-25
AR225318A1 (es) 1982-03-15
FI69455B (fi) 1985-10-31
PT71708A (en) 1980-10-01
AU530398B2 (en) 1983-07-14
IE801729L (en) 1981-02-17
HU182189B (en) 1983-12-28
FI802418A (fi) 1981-02-18
DK355180A (da) 1981-02-18
ZW15780A1 (en) 1981-03-18
LU82713A1 (de) 1982-05-10
BG60798B2 (bg) 1996-03-29
DK150509B (da) 1987-03-16
SE447730B (sv) 1986-12-08
NO802453L (no) 1981-02-18
NO153176B (no) 1985-10-21
ES499957A0 (es) 1982-01-01
FR2463767A1 (fr) 1981-02-27
IT8023283A0 (it) 1980-07-07
IT1220970B (it) 1990-06-21
CS402091A3 (en) 1992-05-13
NZ194628A (en) 1984-09-28
ES494314A0 (es) 1981-11-01
PH15480A (en) 1983-01-27
YU175480A (en) 1983-02-28
FR2463767B1 (fr) 1985-07-12
CU35298A (en) 1982-03-28
SE8005784L (sv) 1981-02-18
ES8201563A1 (es) 1982-01-01
SI8011754A8 (sl) 1997-06-30
DK150509C (da) 1987-10-12
IL60813A (en) 1984-06-29
FI69455C (fi) 1986-02-10
DE19375077I2 (de) 2001-04-12
ES8200355A1 (es) 1981-11-01
MC1345A1 (fr) 1981-06-22
AU6132180A (en) 1981-02-19
CA1128943A (en) 1982-08-03

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