NO151043C - Analogifremgangsmaate ved fremstilling av terapeutisk aktive 9-fluorprednisolonderivater - Google Patents

Analogifremgangsmaate ved fremstilling av terapeutisk aktive 9-fluorprednisolonderivater

Info

Publication number
NO151043C
NO151043C NO780984A NO780984A NO151043C NO 151043 C NO151043 C NO 151043C NO 780984 A NO780984 A NO 780984A NO 780984 A NO780984 A NO 780984A NO 151043 C NO151043 C NO 151043C
Authority
NO
Norway
Prior art keywords
fluorprednisolon
derivatives
preparation
therapeutic active
analogy procedure
Prior art date
Application number
NO780984A
Other languages
English (en)
Norwegian (no)
Other versions
NO151043B (no
NO780984L (no
Inventor
Klaus Annen
Henry Laurent
Helmut Hofmeister
Rudolf Wiechert
Hans Wendt
Joachim-Friedrich Kapp
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2712862A external-priority patent/DE2712862C2/de
Priority claimed from DE19782809732 external-priority patent/DE2809732C2/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO780984L publication Critical patent/NO780984L/no
Publication of NO151043B publication Critical patent/NO151043B/no
Publication of NO151043C publication Critical patent/NO151043C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/001Oxiranes
    • C07J71/0015Oxiranes at position 9(11)

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO780984A 1977-03-21 1978-03-20 Analogifremgangsmaate ved fremstilling av terapeutisk aktive 9-fluorprednisolonderivater NO151043C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2712862A DE2712862C2 (de) 1977-03-21 1977-03-21 Derivate des 9-Fluorprednisolons, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
DE19782809732 DE2809732C2 (de) 1978-03-03 1978-03-03 Derivate des 9-Fluorprednisolons, Verfahren zu ihrer Herstellung, und pharmazeutische Präparate, die diese Wirkstoffe enthalten

Publications (3)

Publication Number Publication Date
NO780984L NO780984L (no) 1978-09-22
NO151043B NO151043B (no) 1984-10-22
NO151043C true NO151043C (no) 1985-01-30

Family

ID=25771793

Family Applications (1)

Application Number Title Priority Date Filing Date
NO780984A NO151043C (no) 1977-03-21 1978-03-20 Analogifremgangsmaate ved fremstilling av terapeutisk aktive 9-fluorprednisolonderivater

Country Status (20)

Country Link
JP (1) JPS53130651A (xx)
AT (1) AT365203B (xx)
AU (1) AU525614B2 (xx)
CA (1) CA1104124A (xx)
CH (1) CH638226A5 (xx)
CS (1) CS202591B2 (xx)
DD (1) DD134955A5 (xx)
DK (1) DK126378A (xx)
ES (1) ES468107A1 (xx)
FR (1) FR2384792A1 (xx)
GB (1) GB1603281A (xx)
GR (1) GR70385B (xx)
IE (1) IE46584B1 (xx)
IL (1) IL54308A (xx)
IT (1) IT1095477B (xx)
LU (1) LU79271A1 (xx)
NO (1) NO151043C (xx)
NZ (1) NZ186735A (xx)
RO (1) RO81525B (xx)
SE (1) SE431656B (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2853785A1 (de) * 1978-12-11 1980-06-19 Schering Ag Neue prednison-derivate, verfahren zu ihrer herstellung, diese verbindungen enthaltende pharmazeutische praeparate und deren verwendung
JPH07116215B2 (ja) * 1989-04-19 1995-12-13 エスエス製薬株式会社 新規なステロイド化合物
JPH07213320A (ja) * 1994-02-04 1995-08-15 Daiwa:Kk 長尺物用バック

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2055221A1 (en) * 1970-11-10 1972-05-18 Laboratorio Chimico Farmaceutico Dr. P. Blasina S.R.L., Mailand (Italien) 17-acyloxy-3-keto-pregn-4-enes prepn - by acylating 17-hydroxy steroids in presence ofstannic chloride
CH529739A (fr) * 1972-02-28 1972-10-31 Sdc Steroidi Dev Co Procédé pour la préparation d'un stéroïde de la série des prégnadiènes
US3832366A (en) * 1973-07-30 1974-08-27 Squibb & Sons Inc Process for preparing 21-chloro-17-acyloxy-20-ketosteroids

Also Published As

Publication number Publication date
AU3434678A (en) 1979-09-27
IE46584B1 (en) 1983-07-27
NZ186735A (en) 1980-10-24
RO81525A (ro) 1983-04-29
AU525614B2 (en) 1982-11-18
JPS6131116B2 (xx) 1986-07-17
GB1603281A (en) 1981-11-25
JPS53130651A (en) 1978-11-14
NO151043B (no) 1984-10-22
CA1104124A (en) 1981-06-30
DD134955A5 (de) 1979-04-04
FR2384792A1 (fr) 1978-10-20
IE780545L (en) 1978-09-21
IL54308A0 (en) 1978-06-15
AT365203B (de) 1981-12-28
LU79271A1 (de) 1978-06-29
SE7803168L (sv) 1978-09-22
DK126378A (da) 1978-09-22
NO780984L (no) 1978-09-22
IT1095477B (it) 1985-08-10
RO81525B (ro) 1983-04-30
ATA195978A (de) 1981-05-15
ES468107A1 (es) 1979-07-01
CS202591B2 (en) 1981-01-30
FR2384792B1 (xx) 1980-04-04
IL54308A (en) 1984-03-30
IT7821364A0 (it) 1978-03-20
SE431656B (sv) 1984-02-20
GR70385B (xx) 1982-10-05
CH638226A5 (en) 1983-09-15

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