NO134219B - - Google Patents
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- Publication number
- NO134219B NO134219B NO932/71A NO93271A NO134219B NO 134219 B NO134219 B NO 134219B NO 932/71 A NO932/71 A NO 932/71A NO 93271 A NO93271 A NO 93271A NO 134219 B NO134219 B NO 134219B
- Authority
- NO
- Norway
- Prior art keywords
- antibiotic
- medium
- growth
- streptomyces
- fermentation
- Prior art date
Links
- 238000000034 method Methods 0.000 claims description 33
- 150000003839 salts Chemical class 0.000 claims description 26
- 241000187390 Amycolatopsis lactamdurans Species 0.000 claims description 17
- 238000002360 preparation method Methods 0.000 claims description 16
- 235000015097 nutrients Nutrition 0.000 claims description 15
- 150000001408 amides Chemical class 0.000 claims description 12
- 244000005700 microbiome Species 0.000 claims description 12
- 241000187747 Streptomyces Species 0.000 claims description 11
- 150000002148 esters Chemical class 0.000 claims description 11
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- 238000000855 fermentation Methods 0.000 description 32
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 description 1
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- 150000007529 inorganic bases Chemical class 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 231100000518 lethal Toxicity 0.000 description 1
- 230000001665 lethal effect Effects 0.000 description 1
- 239000006193 liquid solution Substances 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 229960003646 lysine Drugs 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
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- 239000002480 mineral oil Substances 0.000 description 1
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- 229960005181 morphine Drugs 0.000 description 1
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- 150000002823 nitrates Chemical class 0.000 description 1
- 150000002826 nitrites Chemical class 0.000 description 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 description 1
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- MFDFERRIHVXMIY-UHFFFAOYSA-N procaine Chemical compound CCN(CC)CCOC(=O)C1=CC=C(N)C=C1 MFDFERRIHVXMIY-UHFFFAOYSA-N 0.000 description 1
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- 229960000948 quinine Drugs 0.000 description 1
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- 210000002966 serum Anatomy 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
- C12P35/08—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin disubstituted in the 7 position
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO214572A NO134952C (https=) | 1970-03-13 | 1972-06-16 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1949670A | 1970-03-13 | 1970-03-13 | |
| US5131970A | 1970-06-30 | 1970-06-30 | |
| US9659470A | 1970-12-09 | 1970-12-09 | |
| US05/115,779 US4302578A (en) | 1970-12-09 | 1971-02-16 | Cephalosporin antibiotics |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO134219B true NO134219B (https=) | 1976-05-24 |
| NO134219C NO134219C (https=) | 1976-09-01 |
Family
ID=27486855
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO932/71A NO134219C (https=) | 1970-03-13 | 1971-03-12 |
Country Status (19)
| Country | Link |
|---|---|
| JP (1) | JPS581919B1 (https=) |
| AR (3) | AR200370A1 (https=) |
| BE (1) | BE764160A (https=) |
| CA (1) | CA960169A (https=) |
| CH (5) | CH586226A5 (https=) |
| DD (3) | DD99166A5 (https=) |
| DE (3) | DE2166463A1 (https=) |
| DK (1) | DK131639C (https=) |
| FI (1) | FI51484C (https=) |
| FR (1) | FR2085702B1 (https=) |
| GB (1) | GB1321412A (https=) |
| IE (1) | IE35110B1 (https=) |
| IL (1) | IL36281A (https=) |
| IT (1) | IT1045524B (https=) |
| NL (1) | NL171285C (https=) |
| NO (1) | NO134219C (https=) |
| PH (1) | PH12292A (https=) |
| SE (1) | SE385713B (https=) |
| YU (1) | YU35164B (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1040620A (en) * | 1972-11-14 | 1978-10-17 | Frank J. Urban | 6-alkoxy-6-acylamidopenicillins 7-alkoxy-7-acylamido acetoxycephalosporins and process |
| US4065356A (en) | 1976-02-12 | 1977-12-27 | Merck & Co., Inc. | Production of antibiotic FR-02A (efrotomycin) by streptomyces lactamdurans |
| US4327093A (en) | 1978-10-24 | 1982-04-27 | Fujisawa Pharmaceutical Co., Ltd. | 3,7-Disubstituted-2 or 3-cephem-4-carboxylic acid compounds |
| JPS5931517B2 (ja) * | 1978-12-12 | 1984-08-02 | 山之内製薬株式会社 | 新規７↓−メトキシセファロスポリン誘導体 |
| US4379920A (en) * | 1979-10-31 | 1983-04-12 | Glaxo Group Limited | Cephalosporins |
| EP0137365A3 (en) * | 1983-09-06 | 1986-01-15 | Takeda Chemical Industries, Ltd. | Cephalosporins and their production |
| EP0160745A3 (en) * | 1984-05-07 | 1986-11-05 | Takeda Chemical Industries, Ltd. | Cephem compounds and their production |
| US20070093465A1 (en) | 2003-05-28 | 2007-04-26 | Van Den Berg Marco A | Cephem compound |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4945594A (https=) * | 1972-09-08 | 1974-05-01 |
-
1971
- 1971-02-24 IL IL36281A patent/IL36281A/en unknown
- 1971-03-02 DE DE19712166463 patent/DE2166463A1/de active Pending
- 1971-03-02 DE DE2109854A patent/DE2109854C3/de not_active Expired
- 1971-03-02 DE DE19712166462 patent/DE2166462B2/de active Granted
- 1971-03-08 CH CH1273175A patent/CH586226A5/xx not_active IP Right Cessation
- 1971-03-08 CH CH1294175A patent/CH587856A5/de not_active IP Right Cessation
- 1971-03-08 PH PH12269A patent/PH12292A/en unknown
- 1971-03-08 CH CH333371A patent/CH579576A5/xx not_active IP Right Cessation
- 1971-03-08 CH CH1273075A patent/CH587911A5/xx not_active IP Right Cessation
- 1971-03-08 AR AR234333A patent/AR200370A1/es active
- 1971-03-08 CH CH1294275A patent/CH589655A5/xx not_active IP Right Cessation
- 1971-03-10 IE IE303/71A patent/IE35110B1/xx unknown
- 1971-03-11 FI FI710711A patent/FI51484C/fi active
- 1971-03-11 SE SE7103119A patent/SE385713B/xx unknown
- 1971-03-12 IT IT49017/71A patent/IT1045524B/it active
- 1971-03-12 DD DD164639A patent/DD99166A5/xx unknown
- 1971-03-12 BE BE764160A patent/BE764160A/xx not_active IP Right Cessation
- 1971-03-12 YU YU626/71A patent/YU35164B/xx unknown
- 1971-03-12 FR FR7108668A patent/FR2085702B1/fr not_active Expired
- 1971-03-12 DD DD153734A patent/DD96254A5/xx unknown
- 1971-03-12 CA CA107,642A patent/CA960169A/en not_active Expired
- 1971-03-12 NO NO932/71A patent/NO134219C/no unknown
- 1971-03-12 DD DD164638A patent/DD100002A5/xx unknown
- 1971-03-12 DK DK118171A patent/DK131639C/da not_active IP Right Cessation
- 1971-03-12 NL NLAANVRAGE7103360,A patent/NL171285C/xx not_active IP Right Cessation
- 1971-03-13 JP JP46013630A patent/JPS581919B1/ja active Granted
- 1971-04-19 GB GB2340771*A patent/GB1321412A/en not_active Expired
-
1972
- 1972-05-31 AR AR242279A patent/AR212149A1/es active
-
1974
- 1974-04-29 AR AR253505A patent/AR201142A1/es active
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