NO133973B - - Google Patents

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Publication number
NO133973B
NO133973B NO161179A NO16117966A NO133973B NO 133973 B NO133973 B NO 133973B NO 161179 A NO161179 A NO 161179A NO 16117966 A NO16117966 A NO 16117966A NO 133973 B NO133973 B NO 133973B
Authority
NO
Norway
Prior art keywords
thienylacetamido
acid
cephem
cephaloridine
hydrothiocyanate
Prior art date
Application number
NO161179A
Other languages
English (en)
Norwegian (no)
Other versions
NO133973C (is"
Inventor
Jr H M Higgins
B G Jackson
J L Spencer
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NO133973B publication Critical patent/NO133973B/no
Publication of NO133973C publication Critical patent/NO133973C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
NO161179A 1965-03-05 1966-01-08 NO133973C (is")

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43755365A 1965-03-05 1965-03-05
US437552A US3270012A (en) 1965-03-05 1965-03-05 Method for preparing cephalosporin ca antibiotics

Publications (2)

Publication Number Publication Date
NO133973B true NO133973B (is") 1976-04-20
NO133973C NO133973C (is") 1976-07-28

Family

ID=27031367

Family Applications (1)

Application Number Title Priority Date Filing Date
NO161179A NO133973C (is") 1965-03-05 1966-01-08

Country Status (12)

Country Link
US (1) US3270012A (is")
JP (1) JPS497156B1 (is")
BE (1) BE675299A (is")
BR (1) BR6676470D0 (is")
CH (1) CH492737A (is")
DE (1) DE1670599B2 (is")
DK (1) DK134859B (is")
FR (1) FR1463747A (is")
GB (1) GB1132621A (is")
NL (2) NL6600637A (is")
NO (1) NO133973C (is")
SE (1) SE357566B (is")

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1189306A (en) * 1966-08-10 1970-04-22 Glaxo Lab Ltd Improvements in or relating to Cephalosporin Antibiotics
US3352859A (en) * 1967-03-24 1967-11-14 Lilly Co Eli Process for improving crystal quality of a cephalosporin antibiotic
US4198504A (en) * 1978-11-02 1980-04-15 Bristol-Myers Company [3-(Pyridinium)-7-(naphthyiridinyl carbonylamino)acetamido]cephalosporanic acid derivatives
US4288590A (en) * 1980-02-14 1981-09-08 Bristol-Myers Company 7-[Dα-(4-Hydroxy-1,5-naphthyridine-3-carboxamido)-α-arylacetamido]-3-(N,N-dimethyl-aminomethylpyridinium) methyl-3-cephem-4-carboxylates
US4563449A (en) * 1982-07-19 1986-01-07 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
US4665168A (en) * 1986-04-14 1987-05-12 Eli Lilly And Company Cephalosporin intermediate
CN103772415B (zh) * 2013-12-31 2016-03-30 福建省福抗药业股份有限公司 一种由7-氨基头孢烷酸一步法制备头孢洛宁的制备方法

Also Published As

Publication number Publication date
NO133973C (is") 1976-07-28
CH492737A (de) 1970-06-30
NL6600637A (is") 1966-09-06
US3270012A (en) 1966-08-30
FR1463747A (fr) 1966-12-23
DK134859B (da) 1977-01-31
DE1670599A1 (de) 1970-08-06
GB1132621A (en) 1968-11-06
SE357566B (is") 1973-07-02
NL129633C (is")
JPS497156B1 (is") 1974-02-19
BE675299A (is") 1966-07-18
DE1670599B2 (de) 1977-02-03
BR6676470D0 (pt) 1973-09-06
DK134859C (is") 1977-06-20

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