NO131698B - - Google Patents
Download PDFInfo
- Publication number
- NO131698B NO131698B NO2725/70A NO272570A NO131698B NO 131698 B NO131698 B NO 131698B NO 2725/70 A NO2725/70 A NO 2725/70A NO 272570 A NO272570 A NO 272570A NO 131698 B NO131698 B NO 131698B
- Authority
- NO
- Norway
- Prior art keywords
- pyridyl
- new
- compound
- ethyl
- ethylhydrazine
- Prior art date
Links
- JOOXCMJARBKPKM-UHFFFAOYSA-N 4-oxopentanoic acid Chemical compound CC(=O)CCC(O)=O JOOXCMJARBKPKM-UHFFFAOYSA-N 0.000 claims description 10
- 229940079593 drug Drugs 0.000 claims description 10
- 239000003814 drug Substances 0.000 claims description 10
- HMCWZAZLRFMRPY-UHFFFAOYSA-N 2-pyridin-4-ylethylhydrazine Chemical compound NNCCC1=CC=NC=C1 HMCWZAZLRFMRPY-UHFFFAOYSA-N 0.000 claims description 6
- 210000003169 central nervous system Anatomy 0.000 claims description 6
- 229940040102 levulinic acid Drugs 0.000 claims description 5
- NSLJAVZPTLLIER-UHFFFAOYSA-N 6-methyl-2-(2-pyridin-4-ylethyl)-4,5-dihydropyridazin-3-one Chemical compound O=C1CCC(C)=NN1CCC1=CC=NC=C1 NSLJAVZPTLLIER-UHFFFAOYSA-N 0.000 claims description 4
- 238000000034 method Methods 0.000 claims description 3
- 125000005907 alkyl ester group Chemical group 0.000 claims description 2
- 238000002360 preparation method Methods 0.000 claims description 2
- 150000001875 compounds Chemical class 0.000 description 15
- 230000003213 activating effect Effects 0.000 description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 241000699670 Mus sp. Species 0.000 description 4
- AAILEWXSEQLMNI-UHFFFAOYSA-N 1h-pyridazin-6-one Chemical compound OC1=CC=CN=N1 AAILEWXSEQLMNI-UHFFFAOYSA-N 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- CXOFVDLJLONNDW-UHFFFAOYSA-N Phenytoin Chemical compound N1C(=O)NC(=O)C1(C=1C=CC=CC=1)C1=CC=CC=C1 CXOFVDLJLONNDW-UHFFFAOYSA-N 0.000 description 3
- -1 alkyl levulinate Chemical compound 0.000 description 3
- 239000007795 chemical reaction product Substances 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- UYXAWHWODHRRMR-UHFFFAOYSA-N hexobarbital Chemical compound O=C1N(C)C(=O)NC(=O)C1(C)C1=CCCCC1 UYXAWHWODHRRMR-UHFFFAOYSA-N 0.000 description 3
- 229960002456 hexobarbital Drugs 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 230000004913 activation Effects 0.000 description 2
- 239000003610 charcoal Substances 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 229940064790 dilantin Drugs 0.000 description 2
- 238000004821 distillation Methods 0.000 description 2
- 238000002844 melting Methods 0.000 description 2
- 230000008018 melting Effects 0.000 description 2
- WEXRUCMBJFQVBZ-UHFFFAOYSA-N pentobarbital Chemical compound CCCC(C)C1(CC)C(=O)NC(=O)NC1=O WEXRUCMBJFQVBZ-UHFFFAOYSA-N 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- QMGVPVSNSZLJIA-FVWCLLPLSA-N strychnine Chemical compound O([C@H]1CC(N([C@H]2[C@H]1[C@H]1C3)C=4C5=CC=CC=4)=O)CC=C1CN1[C@@H]3[C@]25CC1 QMGVPVSNSZLJIA-FVWCLLPLSA-N 0.000 description 2
- 206010002091 Anaesthesia Diseases 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- ZAFNJMIOTHYJRJ-UHFFFAOYSA-N Diisopropyl ether Chemical compound CC(C)OC(C)C ZAFNJMIOTHYJRJ-UHFFFAOYSA-N 0.000 description 1
- GMEONFUTDYJSNV-UHFFFAOYSA-N Ethyl levulinate Chemical compound CCOC(=O)CCC(C)=O GMEONFUTDYJSNV-UHFFFAOYSA-N 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 206010067482 No adverse event Diseases 0.000 description 1
- QMGVPVSNSZLJIA-UHFFFAOYSA-N Nux Vomica Natural products C1C2C3C4N(C=5C6=CC=CC=5)C(=O)CC3OCC=C2CN2C1C46CC2 QMGVPVSNSZLJIA-UHFFFAOYSA-N 0.000 description 1
- 241001279009 Strychnos toxifera Species 0.000 description 1
- 208000010513 Stupor Diseases 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 230000001773 anti-convulsant effect Effects 0.000 description 1
- 239000001961 anticonvulsive agent Substances 0.000 description 1
- 229960003965 antiepileptics Drugs 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- RNFNDJAIBTYOQL-UHFFFAOYSA-N chloral hydrate Chemical compound OC(O)C(Cl)(Cl)Cl RNFNDJAIBTYOQL-UHFFFAOYSA-N 0.000 description 1
- 229960002327 chloral hydrate Drugs 0.000 description 1
- ZPEIMTDSQAKGNT-UHFFFAOYSA-N chlorpromazine Chemical compound C1=C(Cl)C=C2N(CCCN(C)C)C3=CC=CC=C3SC2=C1 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 0.000 description 1
- 229960001076 chlorpromazine Drugs 0.000 description 1
- 238000009833 condensation Methods 0.000 description 1
- 230000005494 condensation Effects 0.000 description 1
- 239000012043 crude product Substances 0.000 description 1
- 125000004494 ethyl ester group Chemical group 0.000 description 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 229940058352 levulinate Drugs 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 229960001412 pentobarbital Drugs 0.000 description 1
- 239000008024 pharmaceutical diluent Substances 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 230000001766 physiological effect Effects 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 239000012264 purified product Substances 0.000 description 1
- NWELCUKYUCBVKK-UHFFFAOYSA-N pyridin-2-ylhydrazine Chemical compound NNC1=CC=CC=N1 NWELCUKYUCBVKK-UHFFFAOYSA-N 0.000 description 1
- 125000004076 pyridyl group Chemical group 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 238000001953 recrystallisation Methods 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 229960005453 strychnine Drugs 0.000 description 1
- 150000005846 sugar alcohols Polymers 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
Classifications
-
- H—ELECTRICITY
- H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
- H02K—DYNAMO-ELECTRIC MACHINES
- H02K44/00—Machines in which the dynamo-electric interaction between a plasma or flow of conductive liquid or of fluid-borne conductive or magnetic particles and a coil system or magnetic field converts energy of mass flow into electrical energy or vice versa
- H02K44/02—Electrodynamic pumps
- H02K44/06—Induction pumps
Landscapes
- Engineering & Computer Science (AREA)
- Power Engineering (AREA)
- Structures Of Non-Positive Displacement Pumps (AREA)
- General Induction Heating (AREA)
- Filling Or Discharging Of Gas Storage Vessels (AREA)
- Press Drives And Press Lines (AREA)
- Extraction Or Liquid Replacement (AREA)
- Electromagnetic Pumps, Or The Like (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR6924241A FR2052105A6 (fr) | 1969-07-16 | 1969-07-16 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO131698B true NO131698B (fr) | 1975-04-01 |
| NO131698C NO131698C (fr) | 1975-07-09 |
Family
ID=9037545
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO2725/70A NO131698C (fr) | 1969-07-16 | 1970-07-10 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3656867A (fr) |
| JP (1) | JPS5434164B1 (fr) |
| CA (1) | CA946903A (fr) |
| CH (1) | CH528176A (fr) |
| DE (1) | DE7026816U (fr) |
| FR (1) | FR2052105A6 (fr) |
| GB (1) | GB1313374A (fr) |
| NO (1) | NO131698C (fr) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH604422A5 (fr) * | 1973-02-09 | 1978-09-15 | Alsacienne Atom | |
| JPS49133802U (fr) * | 1973-03-14 | 1974-11-18 | ||
| JPS5121211A (ja) * | 1974-08-15 | 1976-02-20 | Doryokuro Kakunenryo | Denjihonpu |
| JPS5219307A (en) * | 1975-08-06 | 1977-02-14 | Toshiba Corp | Ring shaped straight line induction type electro magetic pump |
| US4255877A (en) * | 1978-09-25 | 1981-03-17 | Brs, Inc. | Athletic shoe having external heel counter |
| JP2014096895A (ja) * | 2012-11-08 | 2014-05-22 | Toshiba Corp | 電磁ポンプ |
| US11049624B2 (en) | 2015-12-07 | 2021-06-29 | Ge-Hitachi Nuclear Energy Americas Llc | Nuclear reactor liquid metal coolant backflow control |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2764095A (en) * | 1954-02-05 | 1956-09-25 | Mine Safety Appliances Co | Polyphase electromagnetic induction pump |
| US3005116A (en) * | 1957-06-04 | 1961-10-17 | English Electric Co Ltd | Discontinuous induction type dynamoelectric machines |
-
1969
- 1969-07-16 FR FR6924241A patent/FR2052105A6/fr not_active Expired
-
1970
- 1970-07-10 NO NO2725/70A patent/NO131698C/no unknown
- 1970-07-14 CH CH1062770A patent/CH528176A/fr not_active IP Right Cessation
- 1970-07-15 US US54946A patent/US3656867A/en not_active Expired - Lifetime
- 1970-07-15 CA CA088,331*7A patent/CA946903A/en not_active Expired
- 1970-07-16 DE DE7026816U patent/DE7026816U/de not_active Expired
- 1970-07-16 JP JP6179970A patent/JPS5434164B1/ja active Pending
- 1970-07-16 GB GB3463470A patent/GB1313374A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CH528176A (fr) | 1972-09-15 |
| DE2035329B2 (de) | 1976-05-13 |
| GB1313374A (en) | 1973-04-11 |
| DE7026816U (de) | 1977-11-17 |
| NO131698C (fr) | 1975-07-09 |
| US3656867A (en) | 1972-04-18 |
| CA946903A (en) | 1974-05-07 |
| JPS5434164B1 (fr) | 1979-10-25 |
| DE2035329A1 (de) | 1971-02-18 |
| FR2052105A6 (fr) | 1971-04-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4052509A (en) | Method for reducing serum uric acid levels | |
| JPS6089474A (ja) | モルフイナン誘導体，その製造方法，及び該化合物を含有する抗腫瘍剤 | |
| JPH075588B2 (ja) | 新規ピコリン誘導体及びこれを含有する医薬 | |
| JPH0224821B2 (fr) | ||
| JPH0153671B2 (fr) | ||
| US3957850A (en) | Phenylacetic acid derivatives | |
| JPS5877868A (ja) | ピリダジン誘導体、その製造法およびそれを有効成分とする中枢神経系賦活剤 | |
| CN101970414A (zh) | 11β-羟基类固醇脱氢酶抑制剂 | |
| NO131698B (fr) | ||
| KR100281867B1 (ko) | 3-(비스-치환페닐메틸렌)옥신돌유도체 | |
| US4034113A (en) | Treatment of senile geriatric patients to restore performance | |
| WO1994006769A1 (fr) | Nouvel ester n-cinnamoyl-2-methyle-5-methoxy-3-indole acetique, production et preparation pharmaceutique contenant ledit ester | |
| JPH02221269A (ja) | 抗レトロウィルスフランケトン類 | |
| JPS6058981A (ja) | ５−ピリジル−１，３−チアゾ−ル誘導体，その製造法およびそれを含んでなる医薬組成物 | |
| SU1053749A3 (ru) | Способ получени 1,2-бис-(никотинамидо)-пропана или его солей с фармацевтически приемлемой кислотой | |
| JPH0625151B2 (ja) | ２−置換シクロヘプトイミダゾ−ル誘導体、抗潰瘍剤及びその製造方法 | |
| CH449652A (fr) | Procédé de préparation de nouvelles hydroxydiamines | |
| IE53738B1 (en) | 1-phenylindazol-3-one compounds, a method of preparing them, intermediates used in the preparation of said compounds and pharmaceutical compositions containing these compounds | |
| US3012032A (en) | 2-[2-(4-pyridyl)-ethyl]-6-methyl-4, 5-dihydro-3-pyridazinone | |
| EP0269383A2 (fr) | 1-Aryloxy-4-[(4-aryl)-1-pipérazinyl]-2-butanols utiles pour traiter des manifestations allergiques | |
| NL8003385A (nl) | (3-alkylamino-2-hydroxypropoxy)-furan-2-carbonzuur- aniliden en werkwijzen voor het bereiden en toepassen van deze verbindingen. | |
| JPS5939872A (ja) | ３−シクロアルキルアミノ−２−ｏｒ−プロポキシシアノピリジン | |
| US3502724A (en) | P-chloro-n-(chloropropyl)-alpha-methyl-phenethylamines and the salts thereof | |
| FI70705B (fi) | Foerfarande foer framstaellning av nya farmakologiskt verkandedekahydrokinolinolderivat | |
| US4182775A (en) | Benzoic acids and process for their preparation |