NO122014B - - Google Patents
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- Publication number
- NO122014B NO122014B NO2537/68A NO253768A NO122014B NO 122014 B NO122014 B NO 122014B NO 2537/68 A NO2537/68 A NO 2537/68A NO 253768 A NO253768 A NO 253768A NO 122014 B NO122014 B NO 122014B
- Authority
- NO
- Norway
- Prior art keywords
- quinoxaline
- amino
- oxides
- compounds
- carbonamido
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 claims description 10
- 238000000034 method Methods 0.000 claims description 6
- 229910052739 hydrogen Inorganic materials 0.000 claims description 4
- 239000001257 hydrogen Substances 0.000 claims description 4
- -1 N-hydroxy-imino form Chemical group 0.000 claims description 3
- 125000003545 alkoxy group Chemical group 0.000 claims description 3
- 125000000217 alkyl group Chemical group 0.000 claims description 3
- 229910052736 halogen Inorganic materials 0.000 claims description 3
- 150000002367 halogens Chemical class 0.000 claims description 3
- 150000002431 hydrogen Chemical class 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 claims description 3
- 239000003929 acidic solution Substances 0.000 claims description 2
- 230000000844 anti-bacterial effect Effects 0.000 claims description 2
- 239000003899 bactericide agent Substances 0.000 claims 1
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 description 9
- 241001465754 Metazoa Species 0.000 description 6
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- 241000699670 Mus sp. Species 0.000 description 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N ammonia Natural products N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- OKEAMBAZBICIFP-UHFFFAOYSA-N 3-oxido-2,1,3-benzoxadiazol-3-ium Chemical compound C1=CC=CC2=[N+]([O-])ON=C21 OKEAMBAZBICIFP-UHFFFAOYSA-N 0.000 description 2
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 description 2
- 229910052784 alkaline earth metal Inorganic materials 0.000 description 2
- 230000037396 body weight Effects 0.000 description 2
- 230000000973 chemotherapeutic effect Effects 0.000 description 2
- 239000013078 crystal Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- CNPURSDMOWDNOQ-UHFFFAOYSA-N 4-methoxy-7h-pyrrolo[2,3-d]pyrimidin-2-amine Chemical compound COC1=NC(N)=NC2=C1C=CN2 CNPURSDMOWDNOQ-UHFFFAOYSA-N 0.000 description 1
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonium chloride Substances [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 description 1
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 description 1
- 208000035143 Bacterial infection Diseases 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 description 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 description 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
- 241000192125 Firmicutes Species 0.000 description 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 description 1
- 206010028470 Mycoplasma infections Diseases 0.000 description 1
- 241000700159 Rattus Species 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 230000007059 acute toxicity Effects 0.000 description 1
- 231100000403 acute toxicity Toxicity 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 150000001342 alkaline earth metals Chemical class 0.000 description 1
- 150000001412 amines Chemical class 0.000 description 1
- 229910021529 ammonia Inorganic materials 0.000 description 1
- 235000011114 ammonium hydroxide Nutrition 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 description 1
- 229910052794 bromium Inorganic materials 0.000 description 1
- 230000003197 catalytic effect Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 229910052801 chlorine Inorganic materials 0.000 description 1
- 239000000460 chlorine Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000013583 drug formulation Substances 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 229910052731 fluorine Inorganic materials 0.000 description 1
- 239000011737 fluorine Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- CUONGYYJJVDODC-UHFFFAOYSA-N malononitrile Chemical compound N#CCC#N CUONGYYJJVDODC-UHFFFAOYSA-N 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000006386 neutralization reaction Methods 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 238000007127 saponification reaction Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/50—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
- C07D241/52—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEF0053057 | 1967-07-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO122014B true NO122014B (da) | 1971-05-10 |
Family
ID=7105962
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO2537/68A NO122014B (da) | 1967-07-26 | 1968-06-26 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US3609151A (da) |
| AT (1) | AT276408B (da) |
| BE (1) | BE718480A (da) |
| CH (1) | CH508638A (da) |
| DE (1) | DE1670895A1 (da) |
| DK (1) | DK126200B (da) |
| ES (1) | ES356496A1 (da) |
| FI (1) | FI49830C (da) |
| FR (2) | FR1603720A (da) |
| GB (1) | GB1174874A (da) |
| IL (1) | IL30132A (da) |
| NL (1) | NL6810547A (da) |
| NO (1) | NO122014B (da) |
| SE (1) | SE341008B (da) |
| YU (1) | YU32929B (da) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4033960A (en) * | 1973-07-31 | 1977-07-05 | Bayer Aktiengesellschaft | 2-Mercaptoquinoxaline-di-N-oxide products and a method for their preparation |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3260720A (en) * | 1963-05-31 | 1966-07-12 | Salsbury Lab | Process of preparing 2-aminoquinoxaline |
-
1967
- 1967-07-26 DE DE19671670895 patent/DE1670895A1/de active Pending
-
1968
- 1968-06-04 CH CH828568A patent/CH508638A/de not_active IP Right Cessation
- 1968-06-05 IL IL30132A patent/IL30132A/xx unknown
- 1968-06-11 FI FI681635A patent/FI49830C/fi active
- 1968-06-12 SE SE07930/68A patent/SE341008B/xx unknown
- 1968-06-26 NO NO2537/68A patent/NO122014B/no unknown
- 1968-07-03 US US742168A patent/US3609151A/en not_active Expired - Lifetime
- 1968-07-24 BE BE718480D patent/BE718480A/xx unknown
- 1968-07-25 DK DK360368AA patent/DK126200B/da unknown
- 1968-07-25 NL NL6810547A patent/NL6810547A/xx unknown
- 1968-07-26 AT AT727568A patent/AT276408B/de active
- 1968-07-26 FR FR1603720D patent/FR1603720A/fr not_active Expired
- 1968-07-26 ES ES356496A patent/ES356496A1/es not_active Expired
- 1968-07-26 GB GB35747/68A patent/GB1174874A/en not_active Expired
- 1968-10-10 FR FR169452A patent/FR7967M/fr not_active Expired
- 1968-12-12 YU YU1674/68A patent/YU32929B/xx unknown
-
1970
- 1970-01-29 US US12530*A patent/US3686400A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US3686400A (en) | 1972-08-22 |
| YU167468A (en) | 1975-06-30 |
| US3609151A (en) | 1971-09-28 |
| AT276408B (de) | 1969-11-25 |
| ES356496A1 (es) | 1970-01-16 |
| YU32929B (en) | 1975-12-31 |
| GB1174874A (en) | 1969-12-17 |
| IL30132A (en) | 1972-05-30 |
| IL30132A0 (en) | 1968-08-22 |
| DK126200B (da) | 1973-06-18 |
| FI49830C (fi) | 1975-10-10 |
| CH508638A (de) | 1971-06-15 |
| BE718480A (da) | 1969-01-24 |
| SE341008B (da) | 1971-12-13 |
| FR7967M (da) | 1970-06-01 |
| NL6810547A (da) | 1969-01-28 |
| DE1670895A1 (de) | 1971-03-18 |
| FR1603720A (da) | 1971-05-24 |
| FI49830B (da) | 1975-06-30 |
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