NL980028I2 - 4"-Keto- en 4;-amino-4"-desoxy-avermectineverbindingen en gesubstitueerde aminoderivaten daarvan. - Google Patents

4"-Keto- en 4;-amino-4"-desoxy-avermectineverbindingen en gesubstitueerde aminoderivaten daarvan.

Info

Publication number
NL980028I2
NL980028I2 NL980028C NL980028C NL980028I2 NL 980028 I2 NL980028 I2 NL 980028I2 NL 980028 C NL980028 C NL 980028C NL 980028 C NL980028 C NL 980028C NL 980028 I2 NL980028 I2 NL 980028I2
Authority
NL
Netherlands
Prior art keywords
amino
deoxy
keto
avermectin compounds
derivatives
Prior art date
Application number
NL980028C
Other languages
English (en)
Other versions
NL980028I1 (nl
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23410826&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NL980028(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of NL980028I1 publication Critical patent/NL980028I1/nl
Publication of NL980028I2 publication Critical patent/NL980028I2/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
NL980028C 1982-03-16 1998-10-26 4"-Keto- en 4;-amino-4"-desoxy-avermectineverbindingen en gesubstitueerde aminoderivaten daarvan. NL980028I2 (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/358,736 US4427663A (en) 1982-03-16 1982-03-16 4"-Keto-and 4"-amino-4"-deoxy avermectin compounds and substituted amino derivatives thereof

Publications (2)

Publication Number Publication Date
NL980028I1 NL980028I1 (nl) 1999-01-04
NL980028I2 true NL980028I2 (nl) 1999-05-03

Family

ID=23410826

Family Applications (1)

Application Number Title Priority Date Filing Date
NL980028C NL980028I2 (nl) 1982-03-16 1998-10-26 4"-Keto- en 4;-amino-4"-desoxy-avermectineverbindingen en gesubstitueerde aminoderivaten daarvan.

Country Status (9)

Country Link
US (1) US4427663A (nl)
EP (1) EP0089202B1 (nl)
JP (1) JPH0633273B2 (nl)
AU (1) AU556527B2 (nl)
DE (1) DE3363686D1 (nl)
MX (1) MX9202896A (nl)
NL (1) NL980028I2 (nl)
NZ (1) NZ203492A (nl)
ZA (1) ZA831784B (nl)

Families Citing this family (138)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4579864A (en) * 1984-06-11 1986-04-01 Merck & Co., Inc. Avermectin and milbemycin 13-keto, 13-imino and 13-amino derivatives
US4547491A (en) * 1984-07-18 1985-10-15 Merck & Co., Inc. C-8A-Oxo-avermectin and milbemycin derivatives, pharmaceutical compositions and method of use
HUT39739A (en) * 1984-12-04 1986-10-29 Ciba Geigy Ag Process for production of derivatives of 13,3-milbemycin and medical preparatives containing thereof
GB2168345B (en) * 1984-12-14 1988-05-25 Ciba Geigy Ag Pesticidal 13b-substituted milbemycin derivatives
US4857509A (en) * 1985-01-22 1989-08-15 Ciba-Geigy Corporation 13β-alkylmilbemycin derivatives for controlling parasites of animals and plants
US4581345A (en) * 1985-04-08 1986-04-08 Merck & Co., Inc. Avermectin 8,9-cyclopropyl compounds, pharmaceutical composition and therapeutic methods of use
US4789684A (en) * 1985-05-02 1988-12-06 Merck & Co., Inc. Anthelmintic fermentation products of microorganisms
US4678774A (en) * 1985-06-06 1987-07-07 Merck & Co., Inc. Novel synergistic compositions
ES8800986A1 (es) * 1985-07-27 1987-12-01 Pfizer Un procedimiento para la produccion de un nuevo derivado de avermectina
US4849446A (en) * 1986-09-12 1989-07-18 American Cyanamid Company 23-imino derivatives of 23-keto compounds
US4916154A (en) * 1986-09-12 1990-04-10 American Cyanamid Company 23-Imino derivatives of LL-F28249 compounds
US4877888A (en) * 1986-09-12 1989-10-31 American Cyanamid Company 13-deoxy-23-imino derivatives of 13-deoxy C-076-aglycone compounds
US4806527A (en) * 1987-03-16 1989-02-21 Merck & Co., Inc. Avermectin derivatives
US4831017A (en) * 1987-06-29 1989-05-16 Merck & Co., Inc. Increased litter size in monogastric domestic animals after treatment in mid-gestation of gravid female with avermectin or milbemycin compound
US4874749A (en) * 1987-07-31 1989-10-17 Merck & Co., Inc. 4"-Deoxy-4-N-methylamino avermectin Bla/Blb
US4847243A (en) * 1987-10-08 1989-07-11 Merck & Co., Inc. Treatment for fescue toxicosis in grazing animals
GB8801908D0 (en) * 1988-01-28 1988-02-24 Glaxo Group Ltd Chemical compounds
US4895837A (en) * 1988-01-29 1990-01-23 Merck & Co., Inc. Avermectin derivatives
US4873224A (en) * 1988-05-23 1989-10-10 Merck & Co., Inc. Avermectin derivatives
GB2220856A (en) * 1988-07-18 1990-01-24 Merck & Co Inc Novel synergistic agricultural insecticidal and acaricidal combinations containing avermectin derivatives
US4906619A (en) * 1988-07-22 1990-03-06 Merck & Co., Inc. Alkyl avermectin derivatives
NZ231773A (en) * 1988-12-23 1992-09-25 Merck & Co Inc Avermectin derivatives, preparation and parasiticidal pharmaceutical compositions thereof
US5015630A (en) * 1989-01-19 1991-05-14 Merck & Co., Inc. 5-oxime avermectin derivatives
US5057499A (en) * 1989-06-02 1991-10-15 Merck & Co. Inc. Avermectin derivatives
US5023241A (en) * 1989-07-31 1991-06-11 Merck & Co., Inc. Avermectin derivatives
US5830875A (en) * 1989-10-30 1998-11-03 Merck & Co., Inc. 24-and 25-substituted avermectin and milbemycin derivatives
US5169839A (en) * 1990-05-11 1992-12-08 Merck & Co., Inc. Derivatives of 3'- and 3"-o-desmethyl avermectin compounds, compositions and methods of treating melmintic and parasitic infections
IL98599A (en) * 1990-06-28 1995-06-29 Merck & Co Inc Stable salts of "4-deoxy-" 4-epi-methylamino abramectin and insecticides containing them
US5208222A (en) * 1991-03-28 1993-05-04 Merck & Co., Inc. 4"-and 4'-alkylthio avermectin derivatives
US5240915A (en) * 1991-10-15 1993-08-31 Merck & Co., Inc. Avermectin derivatives
US5171742A (en) * 1991-10-15 1992-12-15 Merck & Co., Inc. Avermectin compounds with a 6,5-spiroketal ring system ad a 23-acyl substituent
US5162363A (en) * 1992-03-18 1992-11-10 Merck & Co., Inc. 23-nor-23-thia avermectin analogs are active anthelmintic agents
US5229415A (en) * 1992-03-24 1993-07-20 Merck & Co., Inc. Alkylthio alkyl avermectins are active antiparasitic agents
US5362862A (en) * 1993-09-29 1994-11-08 Merck & Co., Inc. Process for 4"-EPI-acetylamino-4"-deoxy-5-oximinoavermectin-B1
US5362863A (en) * 1993-09-29 1994-11-08 Merck & Co., Inc. Process for the preparation of 4"-amino avermectin compounds
US5420260A (en) * 1993-09-29 1995-05-30 Merck & Co., Inc. Process for 4"-epi-acetylamino-4"-deoxy-5-oximinoavermectin B1
US5436355A (en) * 1994-02-03 1995-07-25 Merck & Co., Inc. Process for making avermectin/zein compositions
TW327125B (en) * 1994-02-07 1998-02-21 Merck & Co Inc Composition and method for protecting against pine exhausted
US5578581A (en) * 1994-04-26 1996-11-26 Merck & Co., Inc. Active avermectin analogue
DK1035835T3 (da) * 1997-12-03 2003-12-08 Merck & Co Inc Langtidsvirkende injicerbare formuleringer indeholdende hydrogeneret castorolie
AT501406A1 (de) * 1997-12-23 2006-08-15 Syngenta Participations Ag Verfahren zur bekämpfung von mollusken
ES2359973T3 (es) * 1998-03-19 2011-05-30 MERCK SHARP & DOHME CORP. Composiciones poliméricas líquidas para la liberación controlada de sustancias bioactivas.
KR20010101819A (ko) * 1999-02-09 2001-11-14 오무라 사토시 에바멕틴 유도체
DE19953775A1 (de) 1999-11-09 2001-05-10 Bayer Ag Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften
GB9926887D0 (en) 1999-11-12 2000-01-12 Novartis Ag Organic compounds
US6787342B2 (en) 2000-02-16 2004-09-07 Merial Limited Paste formulations
DE10018370A1 (de) * 2000-04-14 2001-10-18 Bayer Ag Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften
US7144866B2 (en) * 2000-08-09 2006-12-05 The Kitasato Institute Avermectin derivatives
US20040087519A1 (en) * 2000-08-09 2004-05-06 Satoshi Omura Avermectin derivatives
DE10043610A1 (de) * 2000-09-05 2002-03-14 Bayer Ag Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften
EG23124A (en) * 2001-02-27 2004-04-28 Syngenta Participations Ag Avermectins substituted in the 4-position having pesticidal properties
CR6574A (es) * 2001-02-27 2004-10-28 Syngenta Participations Ag Sales de avermectinas substituidas en la posicion 4 con propiedades plaguicidas
US20030068788A1 (en) * 2001-05-16 2003-04-10 Buckel Thomas Gunther Methods and compositions for making emamectin
AR036486A1 (es) * 2001-08-28 2004-09-15 Syngenta Participations Ag Derivados 4"-desoxi-4"-(s)-amino avermectina, composicion plaguicida, procedimiento para la preparacion de esa composicion, metodo para controlar plagas, y uso de estos derivados para preparar una composicion
AR037938A1 (es) * 2001-12-21 2004-12-22 Syngenta Participations Ag Derivados de avermectina b1 que tienen un substituyente de aminosulfoniloxilo en la posicion 4''
DE10203688A1 (de) * 2002-01-31 2003-08-07 Bayer Cropscience Ag Synergistische insektizide Mischungen
DE10207242A1 (de) * 2002-02-21 2003-09-04 Bayer Cropscience Ag Synergistische insektizide Mischungen
DE10207241A1 (de) * 2002-02-21 2003-09-04 Bayer Cropscience Ag Synergistische insektizide Mischungen
AR040073A1 (es) * 2002-05-07 2005-03-16 Syngenta Participations Ag Derivados de 4''-desoxi-4''-(s)-amido avermectina y su uso como plaguicidas
US7001889B2 (en) * 2002-06-21 2006-02-21 Merial Limited Anthelmintic oral homogeneous veterinary pastes
US20060205681A1 (en) * 2002-06-21 2006-09-14 Maryam Moaddeb Homogenous paste formulations
US20040077703A1 (en) * 2002-10-02 2004-04-22 Soll Mark D. Nodulisporic acid derivative spot-on formulations for combating parasites
DE10248257A1 (de) * 2002-10-16 2004-04-29 Bayer Cropscience Ag Wirkstoffkombinationen im insektiziden und akariziden Eigenschaften
GB0302309D0 (en) * 2003-01-31 2003-03-05 Syngenta Participations Ag Avermectin monosaccharide derivatives substituted in the 4 -position having pesticidal properties
GB0302308D0 (en) * 2003-01-31 2003-03-05 Syngenta Participations Ag Avermectin and avermectin monosaccharide derivatives substituted in the 4"- or 4'-position having pesticidal properties
GB0302310D0 (en) * 2003-01-31 2003-03-05 Syngenta Participations Ag Avermectin- and avermectin monosaccharide derivatives substituted in the 4"- or 4' - positionhaving pesticidal properties
GB0302547D0 (en) * 2003-02-04 2003-03-12 Syngenta Participations Ag Avermectins and avermectin monosaccharide substituted in the 4'- and 4" position having pesticidal properties
GB0320176D0 (en) * 2003-08-28 2003-10-01 Syngenta Participations Ag Avermectins and avermectin monosaccharides substitued in the 4'-and 4"-positionhaving pesticidal properties
US7531186B2 (en) 2003-12-17 2009-05-12 Merial Limited Topical formulations comprising 1-N-arylpyrazole derivatives and amitraz
US7666444B2 (en) * 2004-02-02 2010-02-23 Wyeth Antiparasitic composition
US8362086B2 (en) 2005-08-19 2013-01-29 Merial Limited Long acting injectable formulations
US20080027011A1 (en) * 2005-12-20 2008-01-31 Hassan Nached Homogeneous paste and gel formulations
EP1849363A1 (en) * 2006-03-09 2007-10-31 Cheminova A/S Synergistic combination of glutamate- and GABA-gated chloride agonist pesticide and at least one of Vitamin E or Niacin
TWI422328B (zh) 2006-06-19 2014-01-11 Univ California 結合有殺線蟲之種子塗覆物的生物控制劑
CL2007001941A1 (es) 2006-07-05 2008-06-20 Aventis Agriculture Compuestos derivados de 1-aril-5-alquilo pirazol; composicion para tratar animales contra ectoparasitos; uso de dicha composicion; composicion insecticida; uso de dichos compuestos derivados; metodo para preparar composiciones pesticidas; metodo para
DE102007002872A1 (de) 2007-01-15 2008-07-17 Alpha-Biocare Gmbh Verwendung von Avermectin-Derivaten zur Behandlung gegen Parasiten von Fischen
SI2639228T1 (sl) 2007-05-15 2017-03-31 Merial, Inc. Ariloazol-2-il cianoetilamino spojine, postopek njihove izdelave in postopek njihove uporabe
EP2008517A1 (de) 2007-06-29 2008-12-31 Bayer CropScience AG Akarizide Wirkstoffkombinationen
DE102007045922A1 (de) 2007-09-26 2009-04-02 Bayer Cropscience Ag Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften
EP2222168B1 (en) 2007-11-26 2018-09-12 Merial, Inc. Solvent systems for pour-on formulations for combating parasites
EP2127522A1 (de) 2008-05-29 2009-12-02 Bayer CropScience AG Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften
RS58508B1 (sr) 2008-11-14 2019-04-30 Merial Inc Enantiomerno obogaćena paraziticidalna jedinjenja ariloazol-2-il cijanoetilamino
US9173728B2 (en) 2008-11-19 2015-11-03 Merial Inc. Multi-cavity container having offset indentures for dispensing fluids
BRPI0922043B1 (pt) 2008-11-19 2019-04-24 Merial, Inc. Composições compreendendo um aril pirazol e/ou formamidina, métodos e usos das mesmas
TWI457347B (zh) 2008-12-04 2014-10-21 Merial Ltd 二聚合的阿佛菌素（ａｖｅｒｍｅｃｔｉｎ）及密倍脈心（ｍｉｌｂｅｍｙｃｉｎ）衍生物
EP2227951A1 (de) 2009-01-23 2010-09-15 Bayer CropScience AG Verwendung von Enaminocarbonylverbindungen zur Bekämpfung von durch Insekten übertragenen Viren
ES2545738T3 (es) 2009-07-30 2015-09-15 Merial, Inc. Compuestos insecticidas a base de 4-amino-tieno[2,3-d]-pirimidina y procedimientos para su uso
CN102712583B (zh) 2009-12-04 2015-04-08 梅里亚有限公司 农药用双-有机硫化合物
SI3078664T1 (sl) 2009-12-17 2019-05-31 Merial Inc. Antiparazitski dihidroazolni sestavki
US8980896B2 (en) 2009-12-17 2015-03-17 Merial, Inc. Compositions comprising macrocyclic lactone compounds and spirodioxepinoindoles
BR112012018108A2 (pt) 2010-01-22 2015-10-20 Bayer Ip Gmbh combinações acaricidas e/ou inseticidas de ingredientes ativos
UA108641C2 (uk) 2010-04-02 2015-05-25 Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування
EP2382865A1 (de) 2010-04-28 2011-11-02 Bayer CropScience AG Synergistische Wirkstoffkombinationen
EP2568980B1 (en) 2010-05-12 2015-11-11 Merial, Inc. Injectable parasiticidal formulations of levamisole and macrocyclic lactones
LT2640728T (lt) 2010-11-16 2017-03-27 Merial, Inc. Nauji monenzino dariniai, skirti pirmuonių sukeltų infekcijų gydymui
NZ612185A (en) 2010-12-07 2015-10-30 Merial Inc Topical combination formulations of macrocyclic lactones with synthetic pyrethroids
CA2832710C (en) 2011-04-15 2021-05-04 Palle Pedersen Method for controlling nematode pests
EA201400058A1 (ru) 2011-06-27 2014-07-30 Мериал Лимитед Соединения и композиции на основе амидопиридиловых эфиров и их применение против паразитов
US20120329832A1 (en) 2011-06-27 2012-12-27 Jean Delaveau Novel Insect-Repellent Coumarin Derivatives, Syntheses, and Methods of Use
BR122019001738B1 (pt) 2011-09-12 2019-11-05 Merial Inc composições parasiticidas compreendendo um agente ativo de isoxazolina e usos das mesmas
WO2013044118A2 (en) 2011-09-23 2013-03-28 Merial Limited Indirect modeling of new repellent molecules active against insects, acarids, and other arthropods
US9173404B2 (en) 2011-11-17 2015-11-03 Merial, Inc. Compositions comprising an aryl pyrazole and a substituted imidazole, methods and uses thereof
MX358476B (es) 2011-12-02 2018-08-22 Merial Ltd Formulaciones de moxidectina inyectables de larga acción y formas de cristal de moxidectina novedosas.
BR122020022192B1 (pt) 2012-02-06 2021-12-07 Merial, Inc Composições orais veterinárias parasíticas compreendendo ingredientes ativos de ação sistêmica, métodos e uso das mesmas
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
CN103360444B (zh) * 2012-04-03 2016-05-11 浙江海正药业股份有限公司 抗寄生虫药赛拉菌素的合成新工艺
MX367536B (es) 2012-04-20 2019-08-26 Boehringer Ingelheim Animal Health Usa Inc Composiciones parasiticidas que comprenden derivados de benzimidazol, métodos y usos de los mismos.
RS57779B1 (sr) 2012-11-20 2018-12-31 Merial Inc Antihelmintska jedinjenja i kompozicije i postupak za njihovu upotrebu
HUE039467T2 (hu) 2013-01-31 2019-01-28 Merial Inc Eljárás leismaniózis kezelésére és gyógyítására fexinidazol alkalmazásával
CN103214532B (zh) * 2013-02-28 2018-07-06 河北威远生物化工有限公司 阿维菌素B2a/2b胺基衍生物、衍生物盐和阿维菌素B2a/2b胺基衍生物盐的制备方法及用途
NZ719916A (en) 2013-11-01 2017-09-29 Merial Inc Antiparasitic and pesticidal isoxazoline compounds
CA2945766C (en) 2014-04-17 2023-09-26 Merial, Inc. Use of malononitrile compounds for protecting animals from parasites
EP3145925B1 (en) 2014-05-19 2020-11-04 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic compounds
EP3157912B1 (en) 2014-06-19 2019-02-20 Merial, Inc. Parasiticidal compositions comprising indole derivatives, methods and uses thereof
WO2016069983A1 (en) 2014-10-31 2016-05-06 Merial, Inc. Parasiticidal composition comprising fipronil
UY36570A (es) 2015-02-26 2016-10-31 Merial Inc Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
SG10201912724SA (en) 2015-04-08 2020-02-27 Boehringer Ingelheim Animal Health Usa Inc Extended release injectable formulations comprising an isoxazoline active agent, methods and uses thereof
NZ737610A (en) 2015-05-20 2023-07-28 Boehringer Ingelheim Animal Health Usa Inc Anthelmintic depsipeptide compounds
WO2016191389A2 (en) 2015-05-27 2016-12-01 Merial, Inc. Compositions containing antimicrobial igy antibodies, for treatment and prevention of disorders and diseases caused by oral health compromising (ohc) microorganisms
UY37137A (es) 2016-02-24 2017-09-29 Merial Inc Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
CN106380500B (zh) * 2016-08-30 2019-01-29 齐鲁制药（内蒙古）有限公司 一种提高阿维菌素B1a精粉产能和内在质量的浸提方法
US11284618B2 (en) 2016-09-22 2022-03-29 Syngenta Participations Ag Pesticidal mixtures
AU2017344097A1 (en) 2016-10-14 2019-05-02 Boehringer Ingelheim Animal Health USA Inc. Pesticidal and parasiticidal vinyl isoxazoline compounds
MX2019005628A (es) 2016-11-16 2019-12-18 Boehringer Ingelheim Animal Health Usa Inc Compuestos depsipeptidos antihelminticos.
EP3644741B1 (en) 2017-06-26 2023-06-07 Boehringer Ingelheim Animal Health USA Inc. Dual active parasiticidal granule compositions, methods and uses thereof
CA3072936A1 (en) 2017-08-14 2019-02-21 Boehringer Ingelheim Animal Health USA Inc. Pesticidal and parasiticidal pyrazole-isoxazoline compounds
EP3749096A1 (en) 2018-02-08 2020-12-16 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising eprinomectin and praziquantel, methods and uses thereof
CA3106092A1 (en) 2018-07-09 2020-01-16 Boehringer Ingelheim Pharma Gmbh & Co. Kg Anthelminthic heterocyclic compounds
CN108690108B (zh) * 2018-07-27 2022-03-11 河北威远生物化工有限公司 一种磺酰胺基取代的阿维菌素B2a/B2b衍生物及其制备方法与应用
CN113260419A (zh) 2018-11-20 2021-08-13 勃林格殷格翰动物保健美国公司 吲唑基氰基乙基氨基化合物、其组合物、其制备方法和其使用方法
NZ776819A (en) 2019-01-16 2023-04-28 Boehringer Ingelheim Animal Health Usa Inc Topical compositions comprising a neonicotinoid and a macrocyclic lactone, methods and uses thereof
CA3129329A1 (en) 2019-03-01 2020-09-10 Boehringer Ingelheim Animal Health USA Inc. Injectable clorsulon compositions, methods and uses thereof
SG11202109786UA (en) 2019-03-19 2021-10-28 Boehringer Ingelheim Animal Health Usa Inc Anthelmintic aza-benzothiophene and aza-benzofuran compounds
WO2021013825A1 (en) 2019-07-22 2021-01-28 Intervet International B.V. Soft chewable veterinary dosage form
WO2021242581A1 (en) 2020-05-29 2021-12-02 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic heterocyclic compounds
US20220201983A1 (en) 2020-12-21 2022-06-30 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal collar comprising isoxazoline compounds
CN113563395B (zh) * 2021-08-09 2023-06-02 河北威远生物化工有限公司 一种阿维菌素b2衍生物及其制备方法和应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4044123A (en) 1975-05-02 1977-08-23 Schering Corporation 6'-N-alkyl-4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols, methods for their use as antibacterial agents and compositions useful therefor
GB1529243A (en) 1976-02-25 1978-10-18 Pfizer Ltd Process for the preparation of aminoglycoside derivatives and cyclic urethane intermediates for use therein
SE434277B (sv) 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
US4090017A (en) 1977-02-04 1978-05-16 Pfizer Inc. 4-Deoxy-4-substituted amino derivatives of oleandomycin
US4085119A (en) 1977-02-04 1978-04-18 Pfizer Inc. 4-Substituted amino derivatives of oleandomycin
US4098993A (en) 1977-07-25 1978-07-04 Pfizer Inc. Semi-synthetic 4-ureido-oleandomycin derivatives
US4199569A (en) 1977-10-03 1980-04-22 Merck & Co., Inc. Selective hydrogenation products of C-076 compounds and derivatives thereof
NZ188459A (en) * 1977-10-03 1982-09-07 Merck & Co Inc Derivatives of c-076 compounds and pesticidal compositions
US4206205A (en) 1977-10-03 1980-06-03 Merck & Co., Inc. Monosaccharide and aglycone derivatives of C-076
PH15982A (en) * 1977-10-03 1983-05-18 Merck & Co Inc Selective hydrogenation producta of c-076 compounds and derivatives thereof
US4133950A (en) 1978-01-03 1979-01-09 Pfizer Inc. 4"-Deoxy-4"-carbamate and dithiocarbamate derivatives of oleandomycin and its esters
US4200581A (en) * 1978-08-04 1980-04-29 Merck & Co., Inc. Alkyl derivatives of C-076 compounds

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AU556527B2 (en) 1986-11-06
JPH0633273B2 (ja) 1994-05-02
NL980028I1 (nl) 1999-01-04
MX9202896A (es) 1992-06-30
DE3363686D1 (en) 1986-07-03
AU1239383A (en) 1983-09-22
ZA831784B (en) 1984-10-31
US4427663A (en) 1984-01-24
EP0089202B1 (en) 1986-05-28
NZ203492A (en) 1986-05-09
EP0089202A1 (en) 1983-09-21
JPS58167591A (ja) 1983-10-03

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