NL930009I1 - 6(R)-[2-(8'-Acyloxy-2'-methyl-6'-methyl(of waterstof)-polyhydronaftyl-1')-ethyl]-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-onen,de hydroxyzuurvorm van deze pyranonen,de farmaceutisch aanvaardbare zouten van genoemde hydroxyzuren,en de door kleine alkyl-en fenyl-, dimethylamino-of acetylaminoresten oxyzuur, werwijzen ter bereiding ervan en een farmaceutisch antihypercholosterolemisch preparaat, dat dit bevat - Google Patents

6(R)-[2-(8'-Acyloxy-2'-methyl-6'-methyl(of waterstof)-polyhydronaftyl-1')-ethyl]-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-onen,de hydroxyzuurvorm van deze pyranonen,de farmaceutisch aanvaardbare zouten van genoemde hydroxyzuren,en de door kleine alkyl-en fenyl-, dimethylamino-of acetylaminoresten oxyzuur, werwijzen ter bereiding ervan en een farmaceutisch antihypercholosterolemisch preparaat, dat dit bevat

Info

Publication number
NL930009I1
NL930009I1 NL930009C NL930009C NL930009I1 NL 930009 I1 NL930009 I1 NL 930009I1 NL 930009 C NL930009 C NL 930009C NL 930009 C NL930009 C NL 930009C NL 930009 I1 NL930009 I1 NL 930009I1
Authority
NL
Netherlands
Prior art keywords
hydroxy
methyl
preparation
antihypercholosterolemic
polyhydronaphthyl
Prior art date
Application number
NL930009C
Other languages
English (en)
Other versions
NL930009I2 (nl
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27494171&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NL930009(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US06/175,232 external-priority patent/US4293496A/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of NL930009I1 publication Critical patent/NL930009I1/nl
Publication of NL930009I2 publication Critical patent/NL930009I2/nl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30Oxygen atoms, e.g. delta-lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Pyrane Compounds (AREA)
NL930009C 1980-02-04 1993-02-09 6(R)-Ä2-(8'-Acyloxy-2'-methyl-6'-methyl (of waterstof)-poly-hydronafty-1')-ethylÜ-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-onen, de hydroxyzuurvorm van deze pyranonen, de farmaceutisch aanvardbare zouten van genoemde hydroxyzuren, en de door kleinealkyl- en fenyl-, dimethylamino- of acetylaminore sten gesubstitueerde klein-alkylesters van genoemdhydroxyzuur, werkwijzen ter bereiding ervan en ee n farmaceutisch antihypercholesterolemisch preparaat, dat dit bevat. NL930009I2 (nl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US11804980A 1980-02-04 1980-02-04
US11805180A 1980-02-04 1980-02-04
US17546080A 1980-08-05 1980-08-05
US06/175,232 US4293496A (en) 1980-02-04 1980-08-05 6(R)-[2-(8-Hydroxy-2,6-dimethylpolyhydronaphthyl-1)-ethyl]-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-ones

Publications (2)

Publication Number Publication Date
NL930009I1 true NL930009I1 (nl) 1993-04-01
NL930009I2 NL930009I2 (nl) 1993-09-16

Family

ID=27494171

Family Applications (1)

Application Number Title Priority Date Filing Date
NL930009C NL930009I2 (nl) 1980-02-04 1993-02-09 6(R)-Ä2-(8'-Acyloxy-2'-methyl-6'-methyl (of waterstof)-poly-hydronafty-1')-ethylÜ-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-onen, de hydroxyzuurvorm van deze pyranonen, de farmaceutisch aanvardbare zouten van genoemde hydroxyzuren, en de door kleinealkyl- en fenyl-, dimethylamino- of acetylaminore sten gesubstitueerde klein-alkylesters van genoemdhydroxyzuur, werkwijzen ter bereiding ervan en ee n farmaceutisch antihypercholesterolemisch preparaat, dat dit bevat.

Country Status (22)

Country Link
EP (1) EP0033538B1 (nl)
AU (1) AU548996B2 (nl)
CA (1) CA1199322A (nl)
CY (1) CY1404A (nl)
DD (1) DD155989A5 (nl)
DE (1) DE3173042D1 (nl)
DK (1) DK157292C (nl)
ES (1) ES499079A0 (nl)
FI (1) FI78082C (nl)
GR (1) GR74798B (nl)
HK (1) HK16488A (nl)
IE (1) IE51478B1 (nl)
IL (1) IL62044A (nl)
MA (1) MA19054A1 (nl)
MY (1) MY8700745A (nl)
NL (1) NL930009I2 (nl)
NO (2) NO154229C (nl)
NZ (1) NZ196172A (nl)
PT (1) PT72441B (nl)
RO (1) RO82367B (nl)
SG (1) SG61087G (nl)
YU (1) YU28181A (nl)

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Also Published As

Publication number Publication date
ES8609296A1 (es) 1985-10-16
PT72441B (pt) 1984-08-01
NO154229B (no) 1986-05-05
NO1994001I1 (no) 1994-07-01
AU548996B2 (en) 1986-01-09
DD155989A5 (de) 1982-07-21
PT72441A (pt) 1981-03-01
DK46181A (da) 1981-08-05
MA19054A1 (fr) 1981-10-01
IE51478B1 (en) 1987-01-07
FI78082B (fi) 1989-02-28
ES499079A0 (es) 1985-10-16
EP0033538A2 (en) 1981-08-12
NL930009I2 (nl) 1993-09-16
EP0033538A3 (en) 1982-02-24
FI810287L (fi) 1981-08-05
RO82367B (ro) 1984-02-28
HK16488A (en) 1988-03-11
EP0033538B1 (en) 1985-11-27
IL62044A0 (en) 1981-03-31
NO154229C (no) 1986-08-13
DK157292B (da) 1989-12-04
MY8700745A (en) 1987-12-31
IE810204L (en) 1981-08-04
YU28181A (en) 1983-10-31
IL62044A (en) 1987-03-31
SG61087G (en) 1987-10-23
DE3173042D1 (en) 1986-01-09
CA1199322A (en) 1986-01-14
NZ196172A (en) 1985-01-31
RO82367A (ro) 1984-02-21
DK157292C (da) 1990-05-07
AU6657381A (en) 1981-08-13
CY1404A (en) 1988-04-22
FI78082C (fi) 1989-06-12
GR74798B (nl) 1984-07-12
NO810358L (no) 1981-08-05

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