NL9201440A - Triantennaire clusterglycosiden, hun bereiding en toepassing. - Google Patents
Triantennaire clusterglycosiden, hun bereiding en toepassing. Download PDFInfo
- Publication number
- NL9201440A NL9201440A NL9201440A NL9201440A NL9201440A NL 9201440 A NL9201440 A NL 9201440A NL 9201440 A NL9201440 A NL 9201440A NL 9201440 A NL9201440 A NL 9201440A NL 9201440 A NL9201440 A NL 9201440A
- Authority
- NL
- Netherlands
- Prior art keywords
- group
- glycoside
- formula
- residue
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
- C07H15/08—Polyoxyalkylene derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0088—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing unsubstituted amino radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL9201440A NL9201440A (nl) | 1992-08-11 | 1992-08-11 | Triantennaire clusterglycosiden, hun bereiding en toepassing. |
DK93921124T DK0655070T3 (da) | 1992-08-11 | 1993-08-11 | Triantennære klusterglycosider, deres fremstilling og anvendelse |
AT93921124T ATE168694T1 (de) | 1992-08-11 | 1993-08-11 | Triantennar cluster glykoside, ihre herstellung und verwendung |
AU48355/93A AU674160B2 (en) | 1992-08-11 | 1993-08-11 | Triantennary cluster glycosides, their preparation and use |
PCT/NL1993/000169 WO1994004545A1 (en) | 1992-08-11 | 1993-08-11 | Triantennary cluster glycosides, their preparation and use |
ES93921124T ES2122041T3 (es) | 1992-08-11 | 1993-08-11 | Glicosidos triantenarios aglomerados, su preparacion y utilizacion. |
US08/382,022 US5885968A (en) | 1992-08-11 | 1993-08-11 | Triantennary cluster glycosides, their preparation and use |
DE69319912T DE69319912T2 (de) | 1992-08-11 | 1993-08-11 | Triantennar cluster glykoside, ihre herstellung und verwendung |
JP6506123A JPH08502726A (ja) | 1992-08-11 | 1993-08-11 | 3分枝性クラスタグリコシドの調製およびその用途 |
EP93921124A EP0655070B1 (en) | 1992-08-11 | 1993-08-11 | Triantennary cluster glycosides, their preparation and use |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL9201440A NL9201440A (nl) | 1992-08-11 | 1992-08-11 | Triantennaire clusterglycosiden, hun bereiding en toepassing. |
NL9201440 | 1992-08-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
NL9201440A true NL9201440A (nl) | 1994-03-01 |
Family
ID=19861173
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL9201440A NL9201440A (nl) | 1992-08-11 | 1992-08-11 | Triantennaire clusterglycosiden, hun bereiding en toepassing. |
Country Status (10)
Country | Link |
---|---|
US (1) | US5885968A (es) |
EP (1) | EP0655070B1 (es) |
JP (1) | JPH08502726A (es) |
AT (1) | ATE168694T1 (es) |
AU (1) | AU674160B2 (es) |
DE (1) | DE69319912T2 (es) |
DK (1) | DK0655070T3 (es) |
ES (1) | ES2122041T3 (es) |
NL (1) | NL9201440A (es) |
WO (1) | WO1994004545A1 (es) |
Families Citing this family (76)
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WO1996030386A1 (fr) * | 1995-03-31 | 1996-10-03 | Drug Delivery System Institute, Ltd. | Derives d'amidite et derives d'oligonucleotides |
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WO2012058210A1 (en) | 2010-10-29 | 2012-05-03 | Merck Sharp & Dohme Corp. | RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACIDS (siNA) |
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US8932572B2 (en) | 2011-08-26 | 2015-01-13 | Arrowhead Madison Inc. | Poly(vinyl ester) polymers for in vivo nucleic acid delivery |
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CA2893801A1 (en) | 2013-01-30 | 2014-08-07 | F. Hoffmann-La Roche Ag | Lna oligonucleotide carbohydrate conjugates |
WO2014118272A1 (en) | 2013-01-30 | 2014-08-07 | Santaris Pharma A/S | Antimir-122 oligonucleotide carbohydrate conjugates |
LT3013959T (lt) | 2013-06-27 | 2020-03-10 | Roche Innovation Center Copenhagen A/S | Priešprasmiai oligomerai ir konjugatai, nukreirti į pcsk9 |
GB201408623D0 (en) | 2014-05-15 | 2014-07-02 | Santaris Pharma As | Oligomers and oligomer conjugates |
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CA2979703A1 (en) | 2015-03-17 | 2016-09-22 | Arrowhead Pharmaceuticals, Inc. | Compositions and methods for inhibiting gene expression of factor xii |
CA2991639A1 (en) | 2015-08-07 | 2017-02-16 | Arrowhead Pharmaceuticals, Inc. | Rnai therapy for hepatitis b virus infection |
JOP20210043A1 (ar) | 2015-10-01 | 2017-06-16 | Arrowhead Pharmaceuticals Inc | تراكيب وأساليب لتثبيط تعبير جيني للـ lpa |
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WO2022223557A1 (en) | 2021-04-20 | 2022-10-27 | Silence Therapeutics Gmbh | Nucleic acids for inhibiting expression of xdh in a cell |
EP4329876A1 (en) | 2021-04-27 | 2024-03-06 | Silence Therapeutics GmbH | Sirna targeting tmprss6 for the treatment of myeloproliferative disorders |
US11549112B1 (en) | 2021-06-21 | 2023-01-10 | Arrowhead Pharmaceuticals, Inc. | RNAi agents for inhibiting expression of xanthine dehydrogenase (XDH), pharmaceutical compositions thereof, and methods of use |
WO2023031359A1 (en) | 2021-09-02 | 2023-03-09 | Silence Therapeutics Gmbh | Nucleic acids for inhibiting expression of complement factor b (cfb) in a cell |
WO2023233290A1 (en) | 2022-05-31 | 2023-12-07 | Janssen Sciences Ireland Unlimited Company | Rnai agents targeting pd-l1 |
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Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US751219A (en) * | 1904-02-02 | Leaf-turner | ||
US4751219A (en) * | 1985-02-05 | 1988-06-14 | Nederlandse Centrale Organisatie Voor Toegepast-Natuur-Wetenschappelijk Onderzoek | Synthetic glycolipides, a process for the preparation thereof and several uses for these synthetic glycolipides |
FR2637185A1 (fr) * | 1988-10-05 | 1990-04-06 | Ire Celltarg Sa | Vecteurs synthetiques de faible poids moleculaire, utilisation en therapie ciblee et en imagerie medicale et procedes de preparation |
ATE190619T1 (de) * | 1993-09-01 | 2000-04-15 | Akzo Nobel Nv | Biskonjugate, die zwei saccharide und einen spacer enthalten |
-
1992
- 1992-08-11 NL NL9201440A patent/NL9201440A/nl not_active Application Discontinuation
-
1993
- 1993-08-11 DK DK93921124T patent/DK0655070T3/da active
- 1993-08-11 US US08/382,022 patent/US5885968A/en not_active Expired - Fee Related
- 1993-08-11 ES ES93921124T patent/ES2122041T3/es not_active Expired - Lifetime
- 1993-08-11 AU AU48355/93A patent/AU674160B2/en not_active Ceased
- 1993-08-11 EP EP93921124A patent/EP0655070B1/en not_active Expired - Lifetime
- 1993-08-11 DE DE69319912T patent/DE69319912T2/de not_active Expired - Fee Related
- 1993-08-11 JP JP6506123A patent/JPH08502726A/ja not_active Ceased
- 1993-08-11 AT AT93921124T patent/ATE168694T1/de not_active IP Right Cessation
- 1993-08-11 WO PCT/NL1993/000169 patent/WO1994004545A1/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
DE69319912D1 (de) | 1998-08-27 |
DE69319912T2 (de) | 1999-04-15 |
EP0655070A1 (en) | 1995-05-31 |
DK0655070T3 (da) | 1999-04-26 |
WO1994004545A1 (en) | 1994-03-03 |
ATE168694T1 (de) | 1998-08-15 |
AU4835593A (en) | 1994-03-15 |
ES2122041T3 (es) | 1998-12-16 |
AU674160B2 (en) | 1996-12-12 |
EP0655070B1 (en) | 1998-07-22 |
US5885968A (en) | 1999-03-23 |
JPH08502726A (ja) | 1996-03-26 |
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