NL9001772A - Inrichting voor het herhaald automatisch uitvoeren van een thermische cyclus bij de behandeling van monsters. - Google Patents

Inrichting voor het herhaald automatisch uitvoeren van een thermische cyclus bij de behandeling van monsters. Download PDF

Info

Publication number
NL9001772A
NL9001772A NL9001772A NL9001772A NL9001772A NL 9001772 A NL9001772 A NL 9001772A NL 9001772 A NL9001772 A NL 9001772A NL 9001772 A NL9001772 A NL 9001772A NL 9001772 A NL9001772 A NL 9001772A
Authority
NL
Netherlands
Prior art keywords
sample
consist
moving
treatment
track
Prior art date
Application number
NL9001772A
Other languages
English (en)
Dutch (nl)
Original Assignee
Scras
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scras filed Critical Scras
Publication of NL9001772A publication Critical patent/NL9001772A/nl

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B01L7/525—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples with physical movement of samples between temperature zones
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/08—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/088—Channel loops
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346—Heating or cooling arrangements
    • G01N2035/00435—Refrigerated reagent storage

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)
  • Investigating Or Analyzing Materials Using Thermal Means (AREA)
NL9001772A 1989-08-05 1990-08-06 Inrichting voor het herhaald automatisch uitvoeren van een thermische cyclus bij de behandeling van monsters. NL9001772A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8917963 1989-08-05
GB898917963A GB8917963D0 (en) 1989-08-05 1989-08-05 Apparatus for repeated automatic execution of a thermal cycle for treatment of biological samples

Publications (1)

Publication Number Publication Date
NL9001772A true NL9001772A (nl) 1991-03-01

Family

ID=10661242

Family Applications (1)

Application Number Title Priority Date Filing Date
NL9001772A NL9001772A (nl) 1989-08-05 1990-08-06 Inrichting voor het herhaald automatisch uitvoeren van een thermische cyclus bij de behandeling van monsters.

Country Status (30)

Country Link
US (1) US5176203A (fr)
JP (1) JP3058661B2 (fr)
AR (1) AR243600A1 (fr)
AT (1) AT403165B (fr)
AU (1) AU643225B2 (fr)
BE (1) BE1004524A3 (fr)
CA (1) CA2022564C (fr)
CH (1) CH681431A5 (fr)
DE (1) DE4024714C2 (fr)
DK (1) DK185990A (fr)
ES (1) ES2027111A6 (fr)
FI (1) FI903856A0 (fr)
FR (1) FR2650657A1 (fr)
GB (2) GB8917963D0 (fr)
GR (1) GR1000653B (fr)
HK (1) HK33194A (fr)
IE (1) IE65524B1 (fr)
IN (1) IN177441B (fr)
IT (1) IT1243976B (fr)
LU (1) LU87782A1 (fr)
MA (1) MA21926A1 (fr)
MY (1) MY107255A (fr)
NL (1) NL9001772A (fr)
NO (1) NO903423L (fr)
NZ (1) NZ234736A (fr)
OA (1) OA09742A (fr)
PT (1) PT94899B (fr)
SE (1) SE9002566L (fr)
TN (1) TNSN90110A1 (fr)
ZA (1) ZA905935B (fr)

Families Citing this family (159)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5935401A (en) * 1996-09-18 1999-08-10 Aclara Biosciences Surface modified electrophoretic chambers
US6787338B2 (en) * 1990-06-04 2004-09-07 The University Of Utah Method for rapid thermal cycling of biological samples
FR2672231A1 (fr) * 1991-02-01 1992-08-07 Eibet Appareil d'execution automatique repetee d'un cycle thermique, notamment pour l'amplification du nombre d'une sequence definie d'acide nucleique.
US5270183A (en) * 1991-02-08 1993-12-14 Beckman Research Institute Of The City Of Hope Device and method for the automated cycling of solutions between two or more temperatures
US7297313B1 (en) 1991-08-31 2007-11-20 The Regents Of The University Of California Microfabricated reactor, process for manufacturing the reactor, and method of amplification
WO1993008297A1 (fr) * 1991-10-23 1993-04-29 Baylor College Of Medicine Determination d'empreintes relatives a des souches bacteriennes par amplification repetitive de sequences d'adn
US5498392A (en) * 1992-05-01 1996-03-12 Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification device and method
DE69303898T3 (de) * 1992-05-01 2007-01-18 Trustees Of The University Of Pennsylvania Fluessigkeitsbehandlung in mikrofabrizierten analytischen vorrichtungen
US5726026A (en) * 1992-05-01 1998-03-10 Trustees Of The University Of Pennsylvania Mesoscale sample preparation device and systems for determination and processing of analytes
US6953676B1 (en) * 1992-05-01 2005-10-11 Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification device and method
US5587128A (en) * 1992-05-01 1996-12-24 The Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification devices
US5639423A (en) * 1992-08-31 1997-06-17 The Regents Of The University Of Calfornia Microfabricated reactor
WO1994010564A1 (fr) * 1992-11-05 1994-05-11 Evotec Biosystems Gmbh Procede de separation de substances a partir de solutions ou de suspensions diluees
US5433141A (en) * 1993-04-08 1995-07-18 Kraft Foods, Inc. Development of a uniform temperature gradient in a block of cheese
EP0636413B1 (fr) * 1993-07-28 2001-11-14 PE Corporation (NY) Dispositif et procédé d'amplification d'acide nucléique
CA2130517C (fr) * 1993-09-10 1999-10-05 Walter Fassbind Reseau de microplateaux pour appareil de production automatique de cycles de temperatures
CA2130013C (fr) * 1993-09-10 1999-03-30 Rolf Moser Appareil servant a modifier automatiquement la temperature du contenu de differentes eprouvettes
AU8073294A (en) * 1993-10-21 1995-05-08 Abbott Laboratories Apparatus and method for transfer of a fluid sample
US5645801A (en) * 1993-10-21 1997-07-08 Abbott Laboratories Device and method for amplifying and detecting target nucleic acids
AU1527095A (en) * 1994-01-11 1995-08-01 Abbott Laboratories Apparatus and method for thermal cycling nucleic acid assays
US5840573A (en) * 1994-02-01 1998-11-24 Fields; Robert E. Molecular analyzer and method of use
DE4420732A1 (de) * 1994-06-15 1995-12-21 Boehringer Mannheim Gmbh Vorrichtung zur Behandlung von Nukleinsäuren aus einer Probe
DE4435107C1 (de) * 1994-09-30 1996-04-04 Biometra Biomedizinische Analy Miniaturisierter Fluß-Thermocycler
JP3398749B2 (ja) * 1994-11-10 2003-04-21 オーキッド バイオ サイエンシズ， インコーポレイテッド 液体分配システム
US5585069A (en) * 1994-11-10 1996-12-17 David Sarnoff Research Center, Inc. Partitioned microelectronic and fluidic device array for clinical diagnostics and chemical synthesis
US5603351A (en) * 1995-06-07 1997-02-18 David Sarnoff Research Center, Inc. Method and system for inhibiting cross-contamination in fluids of combinatorial chemistry device
US5533567A (en) * 1994-12-14 1996-07-09 The Regents Of The University Of California Method and apparatus for uniform heating and cooling
US5637226A (en) * 1995-08-18 1997-06-10 Az Industries, Incorporated Magnetic fluid treatment
CA2236451A1 (fr) * 1995-11-03 1997-05-09 Zygmunt M. Andrevski Systeme de dosage et procede de deroulement des dosages
US5830657A (en) * 1996-05-01 1998-11-03 Visible Genetics Inc. Method for single-tube sequencing of nucleic acid polymers
CA2252571A1 (fr) * 1996-05-01 1997-11-06 Visible Genetics Inc. Procede et dispositif destines a la production de cycles thermiques et a l'automatisation de la preparation d'echantillons au moyen de ces cycles thermiques
EP0927265A4 (fr) * 1996-06-17 2000-07-12 Trustees Of Board Of Appareil et procede de thermocyclage
US5856194A (en) 1996-09-19 1999-01-05 Abbott Laboratories Method for determination of item of interest in a sample
US5795784A (en) 1996-09-19 1998-08-18 Abbott Laboratories Method of performing a process for determining an item of interest in a sample
GB9621357D0 (en) * 1996-10-12 1996-12-04 Central Research Lab Ltd Heating apparatus
US5882903A (en) * 1996-11-01 1999-03-16 Sarnoff Corporation Assay system and method for conducting assays
US6143496A (en) 1997-04-17 2000-11-07 Cytonix Corporation Method of sampling, amplifying and quantifying segment of nucleic acid, polymerase chain reaction assembly having nanoliter-sized sample chambers, and method of filling assembly
DE19717085C2 (de) * 1997-04-23 1999-06-17 Bruker Daltonik Gmbh Verfahren und Geräte für extrem schnelle DNA-Vervielfachung durch Polymerase-Kettenreaktionen (PCR)
US5965410A (en) 1997-09-02 1999-10-12 Caliper Technologies Corp. Electrical current for controlling fluid parameters in microchannels
AUPO931797A0 (en) * 1997-09-22 1997-10-09 Diatech Pty Ltd Apparatus for amplification and determination of nucleic acids
US6174675B1 (en) 1997-11-25 2001-01-16 Caliper Technologies Corp. Electrical current for controlling fluid parameters in microchannels
US5912129A (en) * 1998-03-05 1999-06-15 Vinayagamoorthy; Thuraiayah Multi-zone polymerase/ligase chain reaction
DE19980632B4 (de) * 1998-04-08 2005-07-07 Universität Heidelberg Verfahren zur Durchführung von Reaktionen zwischen mindestens zwei Reaktionspartnern in wässrigen Reaktionsgemischen
US7799521B2 (en) * 1998-06-24 2010-09-21 Chen & Chen, Llc Thermal cycling
US6780617B2 (en) * 2000-12-29 2004-08-24 Chen & Chen, Llc Sample processing device and method
JP4321738B2 (ja) 1998-06-24 2009-08-26 チェン アンド チェン エルエルシー 液体試料試験システム
US6413780B1 (en) 1998-10-14 2002-07-02 Abbott Laboratories Structure and method for performing a determination of an item of interest in a sample
US6485690B1 (en) 1999-05-27 2002-11-26 Orchid Biosciences, Inc. Multiple fluid sample processor and system
US6977145B2 (en) * 1999-07-28 2005-12-20 Serono Genetics Institute S.A. Method for carrying out a biochemical protocol in continuous flow in a microreactor
AU2756301A (en) 2000-01-03 2001-07-16 Panagenic International, Inc. Compositions comprising genome segments and methods of using the same
GB0005434D0 (en) 2000-03-08 2000-04-26 Secr Defence Reaction system
WO2002022878A1 (fr) * 2000-09-14 2002-03-21 Caliper Technologies Corp. Dispositifs microfluidiques et procedes permettant la mise en oeuvre de reactions dependant de la temperature
JP2003024063A (ja) * 2001-07-12 2003-01-28 Toshio Kawai Ｄｎａの連続増幅方法とその装置
AUPR707101A0 (en) * 2001-08-16 2001-09-06 Corbett Research Pty Ltd Continuous flow thermal device
WO2003022435A2 (fr) 2001-09-11 2003-03-20 Iquum, Inc. Tubes echantillons
KR100442836B1 (ko) * 2001-11-10 2004-08-02 삼성전자주식회사 생화학 유체를 온도가 다른 폐쇄된 챔버 구간을 따라 회전이동시키는 폐쇄 유체 회로 시스템
US7179639B2 (en) * 2002-03-05 2007-02-20 Raveendran Pottathil Thermal strip thermocycler
US6911132B2 (en) 2002-09-24 2005-06-28 Duke University Apparatus for manipulating droplets by electrowetting-based techniques
US8349276B2 (en) * 2002-09-24 2013-01-08 Duke University Apparatuses and methods for manipulating droplets on a printed circuit board
US7329545B2 (en) * 2002-09-24 2008-02-12 Duke University Methods for sampling a liquid flow
US7718421B2 (en) 2003-02-05 2010-05-18 Iquum, Inc. Sample processing
US7041481B2 (en) 2003-03-14 2006-05-09 The Regents Of The University Of California Chemical amplification based on fluid partitioning
US20040224425A1 (en) * 2003-05-08 2004-11-11 Gjerde Douglas T. Biomolecule open channel solid phase extraction systems and methods
EP1659170A1 (fr) * 2003-07-11 2006-05-24 Taiyo Yuden Co., Ltd. Amplificateur d'acide nucleique et procede d'amplification d'acide nucleique
US7927797B2 (en) * 2004-01-28 2011-04-19 454 Life Sciences Corporation Nucleic acid amplification with continuous flow emulsion
US8293471B2 (en) * 2004-01-28 2012-10-23 Marshall University Research Corporation Apparatus and method for a continuous rapid thermal cycle system
JP5297651B2 (ja) * 2004-02-24 2013-09-25 サーマル グラディエント 熱サイクル装置
US8043849B2 (en) * 2004-02-24 2011-10-25 Thermal Gradient Thermal cycling device
WO2005094981A1 (fr) * 2004-03-29 2005-10-13 Agilent Technologies, Inc. Systeme cyclique d'amplification en chaine par polymerase
US7968287B2 (en) 2004-10-08 2011-06-28 Medical Research Council Harvard University In vitro evolution in microfluidic systems
US7398015B2 (en) * 2004-12-10 2008-07-08 Electronics And Telecommunications Research Institute Apparatus for controlling fluid-heating using polymer disk
US20060246493A1 (en) * 2005-04-04 2006-11-02 Caliper Life Sciences, Inc. Method and apparatus for use in temperature controlled processing of microfluidic samples
AU2006247752B2 (en) 2005-05-11 2012-04-12 Advanced Liquid Logic, Inc. Method and device for conducting biochemical or chemical reactions at multiple temperatures
US20070026439A1 (en) * 2005-07-15 2007-02-01 Applera Corporation Fluid processing device and method
US20100137163A1 (en) 2006-01-11 2010-06-03 Link Darren R Microfluidic Devices and Methods of Use in The Formation and Control of Nanoreactors
US20140193807A1 (en) 2006-04-18 2014-07-10 Advanced Liquid Logic, Inc. Bead manipulation techniques
US9476856B2 (en) 2006-04-13 2016-10-25 Advanced Liquid Logic, Inc. Droplet-based affinity assays
US8980198B2 (en) * 2006-04-18 2015-03-17 Advanced Liquid Logic, Inc. Filler fluids for droplet operations
US10078078B2 (en) 2006-04-18 2018-09-18 Advanced Liquid Logic, Inc. Bead incubation and washing on a droplet actuator
US7439014B2 (en) 2006-04-18 2008-10-21 Advanced Liquid Logic, Inc. Droplet-based surface modification and washing
US8809068B2 (en) 2006-04-18 2014-08-19 Advanced Liquid Logic, Inc. Manipulation of beads in droplets and methods for manipulating droplets
US8389297B2 (en) 2006-04-18 2013-03-05 Duke University Droplet-based affinity assay device and system
WO2007123908A2 (fr) * 2006-04-18 2007-11-01 Advanced Liquid Logic, Inc. Opérations en puits multiples à base de gouttelettes
US9675972B2 (en) 2006-05-09 2017-06-13 Advanced Liquid Logic, Inc. Method of concentrating beads in a droplet
US9562837B2 (en) 2006-05-11 2017-02-07 Raindance Technologies, Inc. Systems for handling microfludic droplets
WO2007133710A2 (fr) 2006-05-11 2007-11-22 Raindance Technologies, Inc. Dispositifs microfluidiques et leurs procédés d'utilisation
US10741034B2 (en) 2006-05-19 2020-08-11 Apdn (B.V.I.) Inc. Security system and method of marking an inventory item and/or person in the vicinity
KR101422572B1 (ko) * 2006-09-05 2014-07-30 삼성전자주식회사 핵산 검출을 위한 원심력 기반의 미세유동장치 및 이를포함하는 미세유동시스템
US8273310B2 (en) * 2006-09-05 2012-09-25 Samsung Electronics Co., Ltd. Centrifugal force-based microfluidic device for nucleic acid extraction and microfluidic system including the microfluidic device
EP3527671A1 (fr) * 2006-10-06 2019-08-21 Applied DNA Sciences Inc. Appareil pour un système à cycle thermique rapide en continu
DE102006053451B4 (de) * 2006-11-11 2008-11-27 Microfluidic Chipshop Gmbh Mikrofluidische Plattform zur Temperierung von Substanzen und/oder zur Durchführung von zu temperierenden Reaktionen
US20080176292A1 (en) * 2007-01-23 2008-07-24 Texas A&M University System Portable buoyancy driven pcr thermocycler
US8772046B2 (en) 2007-02-06 2014-07-08 Brandeis University Manipulation of fluids and reactions in microfluidic systems
EP2111554B1 (fr) 2007-02-09 2013-05-08 Advanced Liquid Logic, Inc. Dispositifs actionneurs de gouttelettes et procédés employant des perles magnétiques
WO2008130623A1 (fr) 2007-04-19 2008-10-30 Brandeis University Manipulation de fluides, composants fluidiques et réactions dans des systèmes microfluidiques
EP2425894B1 (fr) 2007-06-21 2016-12-28 Gen-Probe Incorporated Instruments et procédé pour exposer un récipient à plusieurs zones thermiques
WO2009002920A1 (fr) * 2007-06-22 2008-12-31 Advanced Liquid Logic, Inc. Amplification d'acide nucléique à base de gouttelette dans un gradient de température
US8268246B2 (en) * 2007-08-09 2012-09-18 Advanced Liquid Logic Inc PCB droplet actuator fabrication
GB2451900A (en) * 2007-08-17 2009-02-18 Uniqsis Ltd Flow apparatus
US8702938B2 (en) 2007-09-04 2014-04-22 Advanced Liquid Logic, Inc. Droplet actuator with improved top substrate
US20090263870A1 (en) * 2007-09-10 2009-10-22 Agency For Science, Technology And Research System and method for amplifying a nucleic acid molecule
AU2008345138B2 (en) 2007-12-23 2014-05-29 Advanced Liquid Logic, Inc. Droplet actuator configurations and methods of conducting droplet operations
US8852952B2 (en) 2008-05-03 2014-10-07 Advanced Liquid Logic, Inc. Method of loading a droplet actuator
EP2279405B1 (fr) * 2008-05-13 2013-09-18 Advanced Liquid Logic, Inc. Procédés, systèmes et dispositifs associés à un positionneur de gouttelettes
US20110097763A1 (en) * 2008-05-13 2011-04-28 Advanced Liquid Logic, Inc. Thermal Cycling Method
EP2315629B1 (fr) 2008-07-18 2021-12-15 Bio-Rad Laboratories, Inc. Bibliothèque de gouttelettes
US10512910B2 (en) 2008-09-23 2019-12-24 Bio-Rad Laboratories, Inc. Droplet-based analysis method
US9417190B2 (en) 2008-09-23 2016-08-16 Bio-Rad Laboratories, Inc. Calibrations and controls for droplet-based assays
US9598725B2 (en) 2010-03-02 2017-03-21 Bio-Rad Laboratories, Inc. Emulsion chemistry for encapsulated droplets
US8633015B2 (en) 2008-09-23 2014-01-21 Bio-Rad Laboratories, Inc. Flow-based thermocycling system with thermoelectric cooler
US9156010B2 (en) 2008-09-23 2015-10-13 Bio-Rad Laboratories, Inc. Droplet-based assay system
US8709762B2 (en) 2010-03-02 2014-04-29 Bio-Rad Laboratories, Inc. System for hot-start amplification via a multiple emulsion
US9764322B2 (en) 2008-09-23 2017-09-19 Bio-Rad Laboratories, Inc. System for generating droplets with pressure monitoring
US9492797B2 (en) 2008-09-23 2016-11-15 Bio-Rad Laboratories, Inc. System for detection of spaced droplets
US11130128B2 (en) 2008-09-23 2021-09-28 Bio-Rad Laboratories, Inc. Detection method for a target nucleic acid
US9399215B2 (en) 2012-04-13 2016-07-26 Bio-Rad Laboratories, Inc. Sample holder with a well having a wicking promoter
US9132394B2 (en) 2008-09-23 2015-09-15 Bio-Rad Laboratories, Inc. System for detection of spaced droplets
WO2011120020A1 (fr) 2010-03-25 2011-09-29 Quantalife, Inc. Système de transport de gouttelettes à des fins de détection
US8951939B2 (en) 2011-07-12 2015-02-10 Bio-Rad Laboratories, Inc. Digital assays with multiplexed detection of two or more targets in the same optical channel
WO2011120024A1 (fr) 2010-03-25 2011-09-29 Quantalife, Inc. Génération de gouttelettes pour dosages sur gouttelettes
US8926065B2 (en) 2009-08-14 2015-01-06 Advanced Liquid Logic, Inc. Droplet actuator devices and methods
CA3021714C (fr) * 2009-09-02 2021-03-09 Bio-Rad Laboratories, Inc. Systeme de melange de fluides par coalescence d'emulsions multiples
WO2011057197A2 (fr) 2009-11-06 2011-05-12 Advanced Liquid Logic, Inc. Actionneur de gouttelettes intégré pour électrophorèse sur gel et analyse moléculaire
EP2516669B1 (fr) 2009-12-21 2016-10-12 Advanced Liquid Logic, Inc. Analyses d'enzymes sur un diffuseur à gouttelettes
US9399797B2 (en) 2010-02-12 2016-07-26 Raindance Technologies, Inc. Digital analyte analysis
US8535889B2 (en) 2010-02-12 2013-09-17 Raindance Technologies, Inc. Digital analyte analysis
US10351905B2 (en) 2010-02-12 2019-07-16 Bio-Rad Laboratories, Inc. Digital analyte analysis
US9366632B2 (en) 2010-02-12 2016-06-14 Raindance Technologies, Inc. Digital analyte analysis
CA2767113A1 (fr) 2010-03-25 2011-09-29 Bio-Rad Laboratories, Inc. Systeme de detection pour analyses a base de gouttelettes
EP3447155A1 (fr) 2010-09-30 2019-02-27 Raindance Technologies, Inc. Dosages en sandwich dans des gouttelettes
WO2012061444A2 (fr) 2010-11-01 2012-05-10 Hiddessen Amy L Système de formation d'émulsions
EP3859011A1 (fr) 2011-02-11 2021-08-04 Bio-Rad Laboratories, Inc. Procédés permettant de former des gouttelettes mélangées
WO2012112804A1 (fr) 2011-02-18 2012-08-23 Raindance Technoligies, Inc. Compositions et méthodes de marquage moléculaire
JP2014509865A (ja) 2011-03-18 2014-04-24 バイオ−ラッド・ラボラトリーズ・インコーポレーテッド シグナルの組合せ使用による多重化デジタルアッセイ
WO2012149042A2 (fr) 2011-04-25 2012-11-01 Bio-Rad Laboratories, Inc. Procédés et compositions pour l'analyse d'acide nucléique
WO2012154745A2 (fr) 2011-05-09 2012-11-15 Advanced Liquid Logic, Inc. Rétroaction microfluidique utilisant une détection d'impédance
EP3216872B1 (fr) 2011-06-02 2020-04-01 Bio-Rad Laboratories, Inc. Quantification d'enzyme
AU2012279420A1 (en) 2011-07-06 2014-01-30 Advanced Liquid Logic Inc Reagent storage on a droplet actuator
US9513253B2 (en) 2011-07-11 2016-12-06 Advanced Liquid Logic, Inc. Droplet actuators and techniques for droplet-based enzymatic assays
US8658430B2 (en) 2011-07-20 2014-02-25 Raindance Technologies, Inc. Manipulating droplet size
US9446404B2 (en) 2011-07-25 2016-09-20 Advanced Liquid Logic, Inc. Droplet actuator apparatus and system
EP2737089B1 (fr) 2011-07-29 2017-09-06 Bio-rad Laboratories, Inc. Caractérisation de banque par essai numérique
WO2013078216A1 (fr) 2011-11-21 2013-05-30 Advanced Liquid Logic Inc Dosages de la glucose-6-phosphate déshydrogénase
JP6222671B2 (ja) 2012-06-27 2017-11-01 アドバンスト リキッド ロジック インコーポレイテッドＡｄｖａｎｃｅｄ Ｌｉｑｕｉｄ Ｌｏｇｉｃ， Ｉｎｃ． 泡形成を低減するための技術および液滴アクチュエーターの設計
US20140255270A1 (en) * 2013-02-28 2014-09-11 California Institute Of Technology Removing sacrificial layer to form liquid containment structure and methods of use thereof
US9963740B2 (en) 2013-03-07 2018-05-08 APDN (B.V.I.), Inc. Method and device for marking articles
US9168533B2 (en) * 2013-07-17 2015-10-27 CrackerBio, Inc. Thermal cycler device
US11901041B2 (en) 2013-10-04 2024-02-13 Bio-Rad Laboratories, Inc. Digital analysis of nucleic acid modification
CA2926436A1 (fr) 2013-10-07 2015-04-16 Judith Murrah Lecteur multimode d'image et spectral
US9944977B2 (en) 2013-12-12 2018-04-17 Raindance Technologies, Inc. Distinguishing rare variations in a nucleic acid sequence from a sample
WO2015142990A1 (fr) 2014-03-18 2015-09-24 Apdn (B.V.I.) Inc. Marqueurs optiques cryptés pour applications de sécurité
US10745825B2 (en) 2014-03-18 2020-08-18 Apdn (B.V.I.) Inc. Encrypted optical markers for security applications
JP2015223130A (ja) * 2014-05-28 2015-12-14 セイコーエプソン株式会社 物質増幅反応装置及び物質増幅方法
KR102415232B1 (ko) * 2015-04-20 2022-07-04 한국전자통신연구원 마이크로 가열 장치
US11260386B2 (en) 2015-06-05 2022-03-01 The Emerther Company Component of a device, a device, and a method for purifying and testing biomolecules from biological samples
US10647981B1 (en) 2015-09-08 2020-05-12 Bio-Rad Laboratories, Inc. Nucleic acid library generation methods and compositions
WO2017180302A1 (fr) 2016-04-11 2017-10-19 Apdn (B.V.I.) Inc. Procédé de marquage de produits cellulosiques
US10995371B2 (en) 2016-10-13 2021-05-04 Apdn (B.V.I.) Inc. Composition and method of DNA marking elastomeric material
WO2018156352A1 (fr) 2017-02-21 2018-08-30 Apdn (B.V.I) Inc. Particules submicroniques enrobées d'acide nucléique pour une authentification

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA596284A (en) * 1960-04-19 M. Findlay Jacquelyn Electromagnetic liquid metal pump
DE1887821U (de) * 1964-02-20 Berliner Quarz Schmelze mbH Mainz Durchlauferhitzer 8 62 B
US2698127A (en) * 1949-04-06 1954-12-28 Claude A Bowlus Hydraulic transmission unit, pump, or compressor
US2863922A (en) * 1956-10-02 1958-12-09 Hoffmann La Roche Preparation of ketene
GB823110A (en) * 1957-03-26 1959-11-04 Leslie Reginald Blake Improvements relating to electromagnetic interaction pumps
US2964532A (en) * 1957-04-17 1960-12-13 Du Pont Production of pigments
US3574485A (en) * 1958-11-28 1971-04-13 Broido Louis Method and apparatus for movement of liquids by electromagnetic means
US3108060A (en) * 1960-05-10 1963-10-22 Phillips Petroleum Co Loop reactor and process for sulfonating asphalt
US3354642A (en) * 1965-05-18 1967-11-28 Gen Motors Corp Turbomagnetic pump
US3488152A (en) * 1966-03-16 1970-01-06 United Aircraft Corp Boron production
US3518057A (en) * 1966-04-22 1970-06-30 Huron Road Hospital Method and apparatus for thrombus formation time determinations
US3411884A (en) * 1967-04-11 1968-11-19 Atomic Energy Commission Usa Process for concentrating heavy water
US3613386A (en) * 1970-03-23 1971-10-19 Air Prod & Chem Cryogenic freezer control
US3699004A (en) * 1970-08-31 1972-10-17 Technicon Instr Method and apparatus for sample analysis on a continuous flow basis
US3738815A (en) * 1970-10-09 1973-06-12 Dow Chemical Co Reactor for removing olefins from acetylenic and olefin-containing gaseous hydrocarbon mixtures
US4015943A (en) * 1972-12-15 1977-04-05 Chemische Werke Huls Aktiengesellschaft Apparatus for the esterification of terephthalic acid in the gas phase
US4113435A (en) * 1973-07-16 1978-09-12 Massachusetts Institute Of Technology Cryogenically controlled direct fluorination apparatus
US3933200A (en) * 1974-06-21 1976-01-20 Emerson Electric Co. Temperature conditioning means
FR2311764A1 (fr) * 1975-05-23 1976-12-17 Rhone Poulenc Ind Procede et appareil pour la transformation thermique de gypse
US4095952A (en) * 1976-03-16 1978-06-20 Veb Jenapharm Jena Apparatus for making (DL) pantolactone
US4181576A (en) * 1977-03-29 1980-01-01 Phillips Petroleum Company Fermentation method
US4137966A (en) * 1977-04-19 1979-02-06 The United States Of America As Represented By The Secretary Of The Navy Simulation oven
US4372918A (en) * 1978-11-15 1983-02-08 Woods Verle W Flow through pressure reaction apparatus
US4276174A (en) * 1980-03-26 1981-06-30 Union Carbide Corporation Control of sludge temperature in autothermal sludge digestion
EP0094458A1 (fr) * 1982-05-17 1983-11-23 András Tejfalussy Adaptateur de maintien d'échantillon régulant la distribution de température pour créer les conditions pour le traitement par gradient de température dans les fours de traitement thermique ou fourneaux
DE3421778A1 (de) * 1984-06-12 1986-01-02 Karl Dr. 7800 Freiburg Fritz Mikrowellen-erwaermungsverfahren
FR2555363B1 (fr) * 1983-11-18 1986-02-21 Cit Alcatel Machine de report de composants pour circuits hybrides
US4544025A (en) * 1984-01-17 1985-10-01 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration High gradient directional solidification furnace
IE58568B1 (en) * 1984-11-15 1993-10-06 Suiker Unie Method and device for the carrying out of a microbiological or enzymatic process
US5038852A (en) * 1986-02-25 1991-08-13 Cetus Corporation Apparatus and method for performing automated amplification of nucleic acid sequences and assays using heating and cooling steps
CA1339653C (fr) * 1986-02-25 1998-02-03 Larry J. Johnson Appareil servant a l'amplification automatisee de sequences nucleotidiques et d'essais au moyen de cycle de chauffage et de refroidissement
CA1338457C (fr) * 1986-08-22 1996-07-16 Henry A. Erlich Enzyme thermostable purifiee
JPS63174555A (ja) * 1987-01-12 1988-07-19 Power Reactor & Nuclear Fuel Dev Corp 導電式電磁ポンプ
FI77055C (fi) * 1987-05-15 1989-01-10 Limitek Oy Vaermegradient-inkubator.
JPS6426360A (en) * 1987-07-22 1989-01-27 Hitachi Ltd Superconducting piping device
CA1293217C (fr) * 1987-11-09 1991-12-17 Sooyoung Stanford Lee Fermentation a rythme de croissance controle
FI79342C (fi) * 1987-12-23 1989-12-11 Orion Yhtymae Oy Apparat, del av en apparat och foerfarande foer maongfaldigande av nukleinsyror.
GB8807297D0 (en) * 1988-03-26 1988-04-27 Dean P D G Intelligent heating block
DE8813773U1 (de) * 1988-11-03 1989-01-05 Max-Planck-Gesellschaft zur Förderung der Wissenschaften eV, 37073 Göttingen Gerät zum wahlweisen Einstellen der Temperatur einer Probe auf verschiedene Werte
DE8814398U1 (de) * 1988-11-17 1989-02-16 Max-Planck-Gesellschaft zur Förderung der Wissenschaften eV, 3400 Göttingen Thermostatiergerät

Also Published As

Publication number Publication date
DK185990D0 (da) 1990-08-03
CA2022564A1 (fr) 1991-02-06
ATA163290A (de) 1997-04-15
HK33194A (en) 1994-04-22
IT9021209A0 (it) 1990-08-03
ZA905935B (en) 1991-05-29
GB8917963D0 (en) 1989-09-20
OA09742A (fr) 1993-11-30
GB2238005A (en) 1991-05-22
PT94899A (pt) 1992-04-30
US5176203A (en) 1993-01-05
LU87782A1 (fr) 1990-12-11
GR900100580A (en) 1991-12-30
AR243600A1 (es) 1993-08-31
ES2027111A6 (es) 1992-05-16
AU643225B2 (en) 1993-11-11
CH681431A5 (fr) 1993-03-31
IT9021209A1 (it) 1992-02-03
NZ234736A (en) 1992-12-23
IE65524B1 (en) 1995-11-01
NO903423D0 (no) 1990-08-03
PT94899B (pt) 1997-11-28
BE1004524A3 (fr) 1992-12-08
FR2650657A1 (fr) 1991-02-08
MA21926A1 (fr) 1991-04-01
AU6014890A (en) 1991-02-07
IN177441B (fr) 1997-01-18
CA2022564C (fr) 1996-03-05
IT1243976B (it) 1994-06-28
SE9002566D0 (sv) 1990-08-03
FR2650657B1 (fr) 1997-02-28
JPH0383572A (ja) 1991-04-09
AT403165B (de) 1997-11-25
FI903856A0 (fi) 1990-08-03
DK185990A (da) 1991-02-06
GB9016886D0 (en) 1990-09-12
GR1000653B (el) 1992-09-25
JP3058661B2 (ja) 2000-07-04
IE902813A1 (en) 1991-03-27
MY107255A (en) 1995-10-31
GB2238005B (en) 1993-12-15
DE4024714C2 (de) 1999-04-29
TNSN90110A1 (fr) 1991-03-05
DE4024714A1 (de) 1991-02-07
NO903423L (no) 1991-02-06
SE9002566L (sv) 1991-02-06

Similar Documents

Publication Publication Date Title
NL9001772A (nl) Inrichting voor het herhaald automatisch uitvoeren van een thermische cyclus bij de behandeling van monsters.
USRE48788E1 (en) Chemical amplification based on fluid partitioning
Roper et al. Advances in polymerase chain reaction on microfluidic chips
EP1735458B1 (fr) Amplification d'acide nucleique avec emulsion a flux continu
US8163489B2 (en) Method for a continuous rapid thermal cycle system
EP1663497B1 (fr) Systeme d'analyse microfluide
US20030092172A1 (en) Apparatus for circulating carrier fluid
WO2004073863A2 (fr) Appareil
KR20100070977A (ko) 일회용 멀티플렉스 중합효소 연쇄 반응(ｐｃｒ)용 칩 및 장치
WO2001089692A2 (fr) Amplification et detection d'acides nucleiques et detection a l'aide de structures a base de diffusion microfluidique
US20040096831A1 (en) Method and system for hybridizing biological materials
US20230131184A1 (en) Intermittent warming of a biologic sample including a nucleic acid
US20230018570A1 (en) Chemical amplification based on fluid partitioning
KR20120039565A (ko) Ｐｃｒ 전처리 장치, 칩 및 이를 이용한 시료 전처리 방법
Poser et al. Rapid PCR in flow-through Si chip thermocyclers
Dalton et al. Fluorescent melting curve analysis compatible with a flowing polymerase chain reactor
Wittwer et al. RAPID PCR 50
Peters et al. PCR on a Roller Coaster

Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
BN A decision not to publish the application has become irrevocable