NL8901102A - Antilichamen tegen fibrine; voor de bereiding van de antilichamen geschikte immunogene peptiden, werkwijze voor het bepalen van fibrine en farmaceutisch preparaat op basis van de antilichamen. - Google Patents

Antilichamen tegen fibrine; voor de bereiding van de antilichamen geschikte immunogene peptiden, werkwijze voor het bepalen van fibrine en farmaceutisch preparaat op basis van de antilichamen. Download PDF

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Publication number
NL8901102A
NL8901102A NL8901102A NL8901102A NL8901102A NL 8901102 A NL8901102 A NL 8901102A NL 8901102 A NL8901102 A NL 8901102A NL 8901102 A NL8901102 A NL 8901102A NL 8901102 A NL8901102 A NL 8901102A
Authority
NL
Netherlands
Prior art keywords
fibrin
antibodies
amino acid
peptide
antibody
Prior art date
Application number
NL8901102A
Other languages
English (en)
Dutch (nl)
Original Assignee
Tno
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tno filed Critical Tno
Priority to NL8901102A priority Critical patent/NL8901102A/nl
Priority to AT90201065T priority patent/ATE108833T1/de
Priority to DK90201065.1T priority patent/DK0396188T3/da
Priority to DE69010750T priority patent/DE69010750T2/de
Priority to ES90201065T priority patent/ES2060927T3/es
Priority to EP90201065A priority patent/EP0396188B1/fr
Priority to US07/516,428 priority patent/US5124439A/en
Priority to JP2115711A priority patent/JP2634683B2/ja
Publication of NL8901102A publication Critical patent/NL8901102A/nl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6845—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a cytokine, e.g. growth factors, VEGF, TNF, a lymphokine or an interferon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
NL8901102A 1989-05-01 1989-05-01 Antilichamen tegen fibrine; voor de bereiding van de antilichamen geschikte immunogene peptiden, werkwijze voor het bepalen van fibrine en farmaceutisch preparaat op basis van de antilichamen. NL8901102A (nl)

Priority Applications (8)

Application Number Priority Date Filing Date Title
NL8901102A NL8901102A (nl) 1989-05-01 1989-05-01 Antilichamen tegen fibrine; voor de bereiding van de antilichamen geschikte immunogene peptiden, werkwijze voor het bepalen van fibrine en farmaceutisch preparaat op basis van de antilichamen.
AT90201065T ATE108833T1 (de) 1989-05-01 1990-04-26 Antikörper gegen fibrin, immunogene peptide für die herstellung dieser antikörper, verfahren zur bestimmung von fibrin und pharmazeutische zubereitungen auf der basis dieser antikörper.
DK90201065.1T DK0396188T3 (da) 1989-05-01 1990-04-26 Antistoffer mod fibrin, immunogene peptider til fremstilling af disse antistoffer, fremgangsmåde til bestemmelse af fibrin og farmaceutiske præparater baseret på disse antistoffer
DE69010750T DE69010750T2 (de) 1989-05-01 1990-04-26 Antikörper gegen Fibrin, immunogene Peptide für die Herstellung dieser Antikörper, Verfahren zur Bestimmung von Fibrin und pharmazeutische Zubereitungen auf der Basis dieser Antikörper.
ES90201065T ES2060927T3 (es) 1989-05-01 1990-04-26 Anticuerpos contra la fibrina; peptidos inmunogenos adecuados para preparar los anticuerpos, metodo para determinar fibrina y preparacion farmaceutica basada en los anticuerpos.
EP90201065A EP0396188B1 (fr) 1989-05-01 1990-04-26 Anticorps contre la fibrine, peptides immunogènes convenant à la préparation de ces anticorps, méthode de détermination de fibrine et préparations pharmaceutiques à base de ces anticorps
US07/516,428 US5124439A (en) 1989-05-01 1990-04-30 Antibodies against fibrin; immunogenic peptides suitable for preparing the antibodies, method for determining fibrin and pharmaceutical preparation based on the antibodies
JP2115711A JP2634683B2 (ja) 1989-05-01 1990-05-01 フイブリンに対する抗体；抗体の調製に適当な免疫原ペプチド、フイブリンを決定する方法および抗体に基づく製剤

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL8901102 1989-05-01
NL8901102A NL8901102A (nl) 1989-05-01 1989-05-01 Antilichamen tegen fibrine; voor de bereiding van de antilichamen geschikte immunogene peptiden, werkwijze voor het bepalen van fibrine en farmaceutisch preparaat op basis van de antilichamen.

Publications (1)

Publication Number Publication Date
NL8901102A true NL8901102A (nl) 1990-12-03

Family

ID=19854590

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8901102A NL8901102A (nl) 1989-05-01 1989-05-01 Antilichamen tegen fibrine; voor de bereiding van de antilichamen geschikte immunogene peptiden, werkwijze voor het bepalen van fibrine en farmaceutisch preparaat op basis van de antilichamen.

Country Status (8)

Country Link
US (1) US5124439A (fr)
EP (1) EP0396188B1 (fr)
JP (1) JP2634683B2 (fr)
AT (1) ATE108833T1 (fr)
DE (1) DE69010750T2 (fr)
DK (1) DK0396188T3 (fr)
ES (1) ES2060927T3 (fr)
NL (1) NL8901102A (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994009034A1 (fr) * 1992-10-12 1994-04-28 Agen Limited Anticoagulant ciblant les caillots, ses procedes de fabrication et d'utilisation
DE69435072T2 (de) * 1993-11-02 2009-01-29 Mitsubishi Kagaku Iatron, Inc. Antikörper gegen menschliches lösliches fibrin, hybridome, die sie produzieren und immunmessverfahren
CA2188647A1 (fr) * 1994-05-02 1995-11-09 Stewart Anthony Cederholm-Williams Chaines de fibrine de recombinaison, fibrine et homologues de fibrine
DE19729591A1 (de) * 1997-07-10 1999-02-11 Therasorb Medizinische Systeme Mittel zur Behandlung und/oder Prophylaxe von Mikrozirkulationsstörungen
US9814672B2 (en) 2007-03-09 2017-11-14 Susan T. Laing Echogenic vehicle for clinical delivery of plasminogen activator and other fibrin-binding therapeutics to thrombi

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4916070A (en) * 1986-04-14 1990-04-10 The General Hospital Corporation Fibrin-specific antibodies and method of screening for the antibodies
DE3701812A1 (de) * 1987-01-22 1988-08-04 Max Planck Gesellschaft Fibrinspezifischer antikoerper, verfahren zur seiner herstellung und seine verwendung

Also Published As

Publication number Publication date
DE69010750T2 (de) 1994-12-22
DE69010750D1 (de) 1994-08-25
JPH0348159A (ja) 1991-03-01
DK0396188T3 (da) 1994-08-22
ES2060927T3 (es) 1994-12-01
EP0396188B1 (fr) 1994-07-20
US5124439A (en) 1992-06-23
JP2634683B2 (ja) 1997-07-30
ATE108833T1 (de) 1994-08-15
EP0396188A1 (fr) 1990-11-07

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