DK0396188T3 - Antistoffer mod fibrin, immunogene peptider til fremstilling af disse antistoffer, fremgangsmåde til bestemmelse af fibrin og farmaceutiske præparater baseret på disse antistoffer - Google Patents

Antistoffer mod fibrin, immunogene peptider til fremstilling af disse antistoffer, fremgangsmåde til bestemmelse af fibrin og farmaceutiske præparater baseret på disse antistoffer

Info

Publication number
DK0396188T3
DK0396188T3 DK90201065.1T DK90201065T DK0396188T3 DK 0396188 T3 DK0396188 T3 DK 0396188T3 DK 90201065 T DK90201065 T DK 90201065T DK 0396188 T3 DK0396188 T3 DK 0396188T3
Authority
DK
Denmark
Prior art keywords
antibodies
fibrin
produce
pharmaceutical preparations
immunogenic peptides
Prior art date
Application number
DK90201065.1T
Other languages
Danish (da)
English (en)
Inventor
Willem Nieuwenhuizen
Original Assignee
Tno
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tno filed Critical Tno
Application granted granted Critical
Publication of DK0396188T3 publication Critical patent/DK0396188T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6845—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a cytokine, e.g. growth factors, VEGF, TNF, a lymphokine or an interferon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK90201065.1T 1989-05-01 1990-04-26 Antistoffer mod fibrin, immunogene peptider til fremstilling af disse antistoffer, fremgangsmåde til bestemmelse af fibrin og farmaceutiske præparater baseret på disse antistoffer DK0396188T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8901102A NL8901102A (nl) 1989-05-01 1989-05-01 Antilichamen tegen fibrine; voor de bereiding van de antilichamen geschikte immunogene peptiden, werkwijze voor het bepalen van fibrine en farmaceutisch preparaat op basis van de antilichamen.

Publications (1)

Publication Number Publication Date
DK0396188T3 true DK0396188T3 (da) 1994-08-22

Family

ID=19854590

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90201065.1T DK0396188T3 (da) 1989-05-01 1990-04-26 Antistoffer mod fibrin, immunogene peptider til fremstilling af disse antistoffer, fremgangsmåde til bestemmelse af fibrin og farmaceutiske præparater baseret på disse antistoffer

Country Status (8)

Country Link
US (1) US5124439A (fr)
EP (1) EP0396188B1 (fr)
JP (1) JP2634683B2 (fr)
AT (1) ATE108833T1 (fr)
DE (1) DE69010750T2 (fr)
DK (1) DK0396188T3 (fr)
ES (1) ES2060927T3 (fr)
NL (1) NL8901102A (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA937553B (en) * 1992-10-12 1994-05-03 Agen Ltd Clot directed anticoagulant process for making same and methods of use
JP3517754B2 (ja) * 1993-11-02 2004-04-12 株式会社三菱化学ヤトロン 抗ヒト可溶性フィブリン抗体，ハイブリドーマ及び免疫学的測定法
AU709134B2 (en) * 1994-05-02 1999-08-19 E.R. Squibb & Sons, Inc. Recombinant fibrin chains, fibrin and fibrin-homologs
DE19729591A1 (de) * 1997-07-10 1999-02-11 Therasorb Medizinische Systeme Mittel zur Behandlung und/oder Prophylaxe von Mikrozirkulationsstörungen
US9814672B2 (en) 2007-03-09 2017-11-14 Susan T. Laing Echogenic vehicle for clinical delivery of plasminogen activator and other fibrin-binding therapeutics to thrombi

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4916070A (en) * 1986-04-14 1990-04-10 The General Hospital Corporation Fibrin-specific antibodies and method of screening for the antibodies
DE3701812A1 (de) * 1987-01-22 1988-08-04 Max Planck Gesellschaft Fibrinspezifischer antikoerper, verfahren zur seiner herstellung und seine verwendung

Also Published As

Publication number Publication date
JPH0348159A (ja) 1991-03-01
EP0396188B1 (fr) 1994-07-20
EP0396188A1 (fr) 1990-11-07
DE69010750T2 (de) 1994-12-22
ES2060927T3 (es) 1994-12-01
JP2634683B2 (ja) 1997-07-30
US5124439A (en) 1992-06-23
NL8901102A (nl) 1990-12-03
DE69010750D1 (de) 1994-08-25
ATE108833T1 (de) 1994-08-15

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