NL8202626A - Derivaten van 9-(2-hydroxyethoxymethyl)guanine. - Google Patents
Derivaten van 9-(2-hydroxyethoxymethyl)guanine. Download PDFInfo
- Publication number
- NL8202626A NL8202626A NL8202626A NL8202626A NL8202626A NL 8202626 A NL8202626 A NL 8202626A NL 8202626 A NL8202626 A NL 8202626A NL 8202626 A NL8202626 A NL 8202626A NL 8202626 A NL8202626 A NL 8202626A
- Authority
- NL
- Netherlands
- Prior art keywords
- guanine
- amino acid
- hydroxyethoxymethyl
- sup
- esters
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (13)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL8202626A NL8202626A (nl) | 1982-06-29 | 1982-06-29 | Derivaten van 9-(2-hydroxyethoxymethyl)guanine. |
US06/507,712 US4548819A (en) | 1982-06-29 | 1983-06-23 | Derivatives of 9-(2-hydroxyethoxymethyl) guanine |
DE8383106299T DE3380410D1 (en) | 1982-06-29 | 1983-06-28 | Derivatives of 9-(2-hydroxyethoxymethyl)guanine |
IL69095A IL69095A (en) | 1982-06-29 | 1983-06-28 | 9-(2-hydroxyethoxymethyl)-guanine derivatives,their preparation and pharmaceutical compositions containing them |
EP83106299A EP0099493B1 (en) | 1982-06-29 | 1983-06-28 | Derivatives of 9-(2-hydroxyethoxymethyl)guanine |
GB08317504A GB2122618B (en) | 1982-06-29 | 1983-06-28 | Purine derivatives |
CA000431347A CA1208637A (en) | 1982-06-29 | 1983-06-28 | Derivatives of 9-(2-hydroxyethoxymethyl)guanine |
FI832355A FI76087C (sv) | 1982-06-29 | 1983-06-28 | Förfarande för framställning av terapeutiskt aktiva 9-(2-hydroxietoxim etyl)guaninderivat |
AT83106299T ATE45580T1 (de) | 1982-06-29 | 1983-06-28 | 9-(2-hydroxyethoxymethyl)guanin-derivate. |
JP58116807A JPS5910587A (ja) | 1982-06-29 | 1983-06-28 | グアニン誘導体 |
HU832337A HU189709B (en) | 1982-06-29 | 1983-06-28 | Process for preparing ester derivatives of 9-/2-hydroxy-ethoxy-methyl/-guanine |
DK297483A DK159444C (da) | 1982-06-29 | 1983-06-28 | Analogifremgangsmaade til fremstilling af derivater af 9-(2-hydroxyethoxymethyl)guanin |
MYPI87002887A MY102248A (en) | 1982-06-29 | 1987-10-09 | Derivatives of 9-(2-hydroxyethoxymethyl) guanine |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL8202626A NL8202626A (nl) | 1982-06-29 | 1982-06-29 | Derivaten van 9-(2-hydroxyethoxymethyl)guanine. |
NL8202626 | 1982-06-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
NL8202626A true NL8202626A (nl) | 1984-01-16 |
Family
ID=19839947
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL8202626A NL8202626A (nl) | 1982-06-29 | 1982-06-29 | Derivaten van 9-(2-hydroxyethoxymethyl)guanine. |
Country Status (13)
Country | Link |
---|---|
US (1) | US4548819A (sv) |
EP (1) | EP0099493B1 (sv) |
JP (1) | JPS5910587A (sv) |
AT (1) | ATE45580T1 (sv) |
CA (1) | CA1208637A (sv) |
DE (1) | DE3380410D1 (sv) |
DK (1) | DK159444C (sv) |
FI (1) | FI76087C (sv) |
GB (1) | GB2122618B (sv) |
HU (1) | HU189709B (sv) |
IL (1) | IL69095A (sv) |
MY (1) | MY102248A (sv) |
NL (1) | NL8202626A (sv) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8513460D0 (en) * | 1985-05-29 | 1985-07-03 | Glaxo Group Ltd | Chemical compounds |
GB8719367D0 (en) * | 1987-08-15 | 1987-09-23 | Wellcome Found | Therapeutic compounds |
AP55A (en) * | 1987-08-15 | 1989-09-26 | The Wellcome Foundation Ltd | Therapeutic Acyclic Nucleosides |
GB8725939D0 (en) * | 1987-11-05 | 1987-12-09 | Wellcome Found | Therapeutic compounds |
US4943579A (en) * | 1987-10-06 | 1990-07-24 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Water soluble prodrugs of camptothecin |
IT1223604B (it) * | 1987-12-24 | 1990-09-29 | Co Pharma Corp Srl | Derivati purinici ad azione farmacologica |
GB8800312D0 (en) * | 1988-01-07 | 1988-02-10 | Glaxo Group Ltd | Process |
GB8829571D0 (en) * | 1988-12-19 | 1989-02-08 | Wellcome Found | Antiviral compounds |
AU618436B2 (en) * | 1988-12-19 | 1991-12-19 | Wellcome Foundation Limited, The | Antiviral cytosine and guanine derivatives |
GB8904855D0 (en) * | 1989-03-03 | 1989-04-12 | Beecham Group Plc | Pharmaceutical treatment |
US5451799A (en) * | 1992-12-28 | 1995-09-19 | Matsushita Electric Industrial Co., Ltd. | MOS transistor for protection against electrostatic discharge |
US5831075A (en) * | 1993-06-10 | 1998-11-03 | Rolabo Sl | Amino acid ester of nucleoside analogues |
GB9320316D0 (en) * | 1993-10-01 | 1993-11-17 | Smithkline Beecham Plc | Pharmaceuticals |
TW282470B (sv) * | 1993-11-18 | 1996-08-01 | Ajinomoto Kk | |
EP0665229B1 (en) * | 1994-02-01 | 1999-11-17 | Ajinomoto Co., Inc. | Process for the production of nucleic acid base derivatives |
US5994361A (en) * | 1994-06-22 | 1999-11-30 | Biochem Pharma | Substituted purinyl derivatives with immunomodulating activity |
US5856481A (en) * | 1994-07-28 | 1999-01-05 | Syntex (U.S.A.) Inc. | 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative |
PE32296A1 (es) * | 1994-07-28 | 1996-08-07 | Hoffmann La Roche | Ester de l-monovalina derivado de 2-(2-amino-1,6-dihidro-6-oxo-purin-9-il) metoxi-1,3-propandiol y sus sales farmaceuticamente aceptables |
US5543414A (en) * | 1994-07-28 | 1996-08-06 | Syntex (Usa) Inc. | Achiral amino acid acyl esters of ganciclovir and its derivatives |
US6040446A (en) | 1996-01-26 | 2000-03-21 | Syntex (U.S.A.) Inc. | Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol derivative |
US5756736A (en) * | 1996-01-26 | 1998-05-26 | Syntex (U.S.A.) Inc. | Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative |
ES2180923T5 (es) * | 1996-01-26 | 2005-10-16 | F. Hoffmann-La Roche Ag | Proceso para la preparacion de derivados de purina. |
US5840890A (en) * | 1996-01-26 | 1998-11-24 | Syntex (U.S.A.) Inc. | Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative |
US5700936A (en) * | 1996-01-26 | 1997-12-23 | Syntex (U.S.A.) Inc. | Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol valinate |
US5869493A (en) | 1996-02-16 | 1999-02-09 | Medivir Ab | Acyclic nucleoside derivatives |
US6703394B2 (en) | 1996-02-16 | 2004-03-09 | Medivir Ab | Acyclic nucleoside derivatives |
CN100560073C (zh) | 2001-12-14 | 2009-11-18 | 法玛塞特公司 | 用于治疗病毒感染的n4-酰基胞嘧啶核苷 |
US20070293517A1 (en) * | 2004-06-09 | 2007-12-20 | Ramot At Tel Aviv University Ltd. | Derivatives Of Chemotherapeutic Agents With A Formaldehyde Releasing Moiety |
US7846937B2 (en) * | 2005-05-25 | 2010-12-07 | Eli Lilly And Company | Cyclopropanecarboxylate esters of acyclovir |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1523865A (en) * | 1974-09-02 | 1978-09-06 | Wellcome Found | Purine compunds and salts thereof |
JPS52105195A (en) * | 1976-03-01 | 1977-09-03 | Wellcome Found | Substituted purine |
US4060616A (en) * | 1976-03-01 | 1977-11-29 | Burroughs Wellcome Co. | Purine derivatives with repeating unit |
AU515553B2 (en) * | 1976-03-01 | 1981-04-09 | The Wellcome Foundation Limited | Purine derivatives |
-
1982
- 1982-06-29 NL NL8202626A patent/NL8202626A/nl not_active Application Discontinuation
-
1983
- 1983-06-23 US US06/507,712 patent/US4548819A/en not_active Expired - Lifetime
- 1983-06-28 JP JP58116807A patent/JPS5910587A/ja active Granted
- 1983-06-28 HU HU832337A patent/HU189709B/hu unknown
- 1983-06-28 EP EP83106299A patent/EP0099493B1/en not_active Expired
- 1983-06-28 DK DK297483A patent/DK159444C/da not_active IP Right Cessation
- 1983-06-28 AT AT83106299T patent/ATE45580T1/de not_active IP Right Cessation
- 1983-06-28 FI FI832355A patent/FI76087C/sv not_active IP Right Cessation
- 1983-06-28 IL IL69095A patent/IL69095A/xx not_active IP Right Cessation
- 1983-06-28 CA CA000431347A patent/CA1208637A/en not_active Expired
- 1983-06-28 GB GB08317504A patent/GB2122618B/en not_active Expired
- 1983-06-28 DE DE8383106299T patent/DE3380410D1/de not_active Expired
-
1987
- 1987-10-09 MY MYPI87002887A patent/MY102248A/en unknown
Also Published As
Publication number | Publication date |
---|---|
FI76087B (fi) | 1988-05-31 |
GB2122618B (en) | 1985-11-13 |
FI832355A0 (fi) | 1983-06-28 |
DK297483A (da) | 1983-12-30 |
IL69095A0 (en) | 1983-10-31 |
GB2122618A (en) | 1984-01-18 |
EP0099493B1 (en) | 1989-08-16 |
ATE45580T1 (de) | 1989-09-15 |
EP0099493A1 (en) | 1984-02-01 |
DK159444C (da) | 1991-03-18 |
DK297483D0 (da) | 1983-06-28 |
CA1208637A (en) | 1986-07-29 |
DE3380410D1 (en) | 1989-09-21 |
HU189709B (en) | 1986-07-28 |
MY102248A (en) | 1992-05-15 |
IL69095A (en) | 1985-11-29 |
JPS5910587A (ja) | 1984-01-20 |
FI832355L (fi) | 1983-12-30 |
FI76087C (sv) | 1988-09-09 |
US4548819A (en) | 1985-10-22 |
DK159444B (da) | 1990-10-15 |
GB8317504D0 (en) | 1983-08-03 |
JPH04990B2 (sv) | 1992-01-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A1B | A search report has been drawn up | ||
A85 | Still pending on 85-01-01 | ||
BV | The patent application has lapsed |