NL8005890A - 4,4 digesubstitueerde piperidinobutyrofenonen en zouten daarvan. - Google Patents

4,4 digesubstitueerde piperidinobutyrofenonen en zouten daarvan. Download PDF

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Publication number
NL8005890A
NL8005890A NL8005890A NL8005890A NL8005890A NL 8005890 A NL8005890 A NL 8005890A NL 8005890 A NL8005890 A NL 8005890A NL 8005890 A NL8005890 A NL 8005890A NL 8005890 A NL8005890 A NL 8005890A
Authority
NL
Netherlands
Prior art keywords
compound
formula
group
cyano
salts
Prior art date
Application number
NL8005890A
Other languages
English (en)
Dutch (nl)
Original Assignee
Richardson Merrell Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richardson Merrell Inc filed Critical Richardson Merrell Inc
Publication of NL8005890A publication Critical patent/NL8005890A/nl

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/30Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
    • C07D211/32Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
NL8005890A 1979-10-27 1980-10-27 4,4 digesubstitueerde piperidinobutyrofenonen en zouten daarvan. NL8005890A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8894279A 1979-10-27 1979-10-27
US8894279 1979-10-27

Publications (1)

Publication Number Publication Date
NL8005890A true NL8005890A (nl) 1981-04-29

Family

ID=22214421

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8005890A NL8005890A (nl) 1979-10-27 1980-10-27 4,4 digesubstitueerde piperidinobutyrofenonen en zouten daarvan.

Country Status (12)

Country Link
JP (1) JPS5673061A (ja)
AU (1) AU6369480A (ja)
BE (1) BE885894A (ja)
CA (1) CA1148162A (ja)
DE (1) DE3039974A1 (ja)
ES (1) ES8201550A1 (ja)
FR (1) FR2468592A1 (ja)
GB (1) GB2061937A (ja)
IL (1) IL61340A0 (ja)
IT (1) IT1146198B (ja)
NL (1) NL8005890A (ja)
ZA (1) ZA806501B (ja)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ577114A (en) * 2006-12-19 2011-12-22 Hoffmann La Roche Heteroaryl pyrrolidinyl and piperidinyl ketone derivatives

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE713746C (de) * 1939-03-31 1941-11-18 I G Farbenindustrie Akt Ges Verfahren zur Darstellung von 4-Arylpiperidyl-4-ketonen
US3080372A (en) * 1960-03-25 1963-03-05 Res Lab Dr C Janssen 1-aroylalkyl-4-arylpiperidine derivatives
CH492708A (de) * 1968-01-11 1970-06-30 Geigy Ag J R Verfahren zur Herstellung von neuen Piperidinderivaten
CH498836A (de) * 1968-12-20 1970-11-15 Geigy Ag J R Verfahren zur Herstellung von neuen Piperidinderivaten
US3852455A (en) * 1970-11-27 1974-12-03 Richardson Merrell Inc 4-{8 4({60 hydroxybenzyl)piperidino{9 -4-fluorobutyrophenone derivatives as tranquilizers
ZA717147B (en) * 1970-11-27 1972-07-26 Richardson Merrell Inc 4-(4-(alpha-hydroxybenzyl)piperidino)-4'-fluorobutyrophenone derivatives
US3888867A (en) * 1972-05-03 1975-06-10 Richardson Merrell Inc 4-(4-(alpha-hydroxybenzyl)piperidino)4'-fluorobutyrophenone derivatives
US4101662A (en) * 1973-05-03 1978-07-18 A. H. Robins Company, Incorporated Method for inhibiting emesis and compositions therefor
SE7409245L (ja) * 1973-07-19 1975-01-20 Robins Co Inc A H
GB1535791A (en) * 1975-05-07 1978-12-13 Ferrosan Ab Derivatives of 4-piperidinol
CH602642A5 (ja) * 1975-11-14 1978-07-31 Orgamol Sa
US4335127A (en) * 1979-01-08 1982-06-15 Janssen Pharmaceutica, N.V. Piperidinylalkyl quinazoline compounds, composition and method of use

Also Published As

Publication number Publication date
BE885894A (fr) 1981-02-16
IL61340A0 (en) 1980-12-31
FR2468592A1 (fr) 1981-05-08
ES496204A0 (es) 1981-12-01
JPS5673061A (en) 1981-06-17
DE3039974A1 (de) 1981-05-07
ES8201550A1 (es) 1981-12-01
FR2468592B1 (ja) 1983-08-05
AU6369480A (en) 1981-04-30
IT1146198B (it) 1986-11-12
CA1148162A (en) 1983-06-14
ZA806501B (en) 1981-10-28
GB2061937A (en) 1981-05-20
IT8049998A0 (it) 1980-10-24

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Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
BV The patent application has lapsed